Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

Tatemoto, K., Carlquist, M., & Mutt, V. (1982) · Nature · doi:10.1038/296659a0 · Cited by 2,254

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

Clark, J. T., Kalra, P. S., Crowley, W. R., & Kalra, S. P. (1984) · Endocrinology · doi:10.1210/endo-115-1-427 · Cited by 1,276

Neuropeptide Y Distribution in the Rat Brain

Allen, Y. S., Adrian, T. E., Allen, J. M., Tatemoto, K., Crow, T. J., Bloom, S. R., & Polak, J. M. (1983) · Science · doi:10.1126/science.6136091 · Cited by 1,097

The anatomy of neuropeptide-y-containing neurons in rat brain

Chronwall, B. M., DiMaggio, D. A., Massari, V. J., Pickel, V. M., Ruggiero, D. A., & O’Donohue, T. L. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90260-x · Cited by 1,088

Hypothalamic lesions and adiposity in the rat

Hetherington, A. W., & Ranson, S. W. (1940) · The Anatomical Record · doi:10.1002/ar.1090780203 · Cited by 1,028

Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior.

Stanley, B. G., & LEIBOWITZ, S. F. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.11.3940 · Cited by 741

Neuropeptide Y distribution in human brain

Adrian, T. E., Allen, J. M., Bloom, S. R., Ghatei, M. A., Rossor, M. N., Roberts, G. W., Crow, T. J., Tatemoto, K., & Polak, J. M. (1983) · Nature · doi:10.1038/306584a0 · Cited by 701

Neuroreptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus

Stanley, B. G., & LEIBOWITZ, S. F. (1984) · Life Sciences · doi:10.1016/0024-3205(84)90032-8 · Cited by 665

Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus

Sawchenko, P. E., Swanson, L. W., Grzanna, R., Howe, P. R. C., Bloom, S. R., & Polak, J. M. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902410203 · Cited by 663

Paraventricular nucleus: A primary site mediating adrenergic stimulation of feeding and drinking

LEIBOWITZ, S. F. (1978) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(78)90333-7 · Cited by 439

Forebrain and hindbrain involvement of neuropeptide Y in ingestive behaviors of rats

Steinman, J. L., Gunion, M. W., & Morley, J. E. (1994) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(94)90001-9 · Cited by 27

Regulation of neuropeptide Y release from hypothalamic slices by melanocortin-4 agonists and leptin

King, P., Widdowson, P. S., Doods, H. N., & Williams, G. (2000) · Peptides · doi:10.1016/s0196-9781(99)00168-0 · Cited by 27

Neuropeptides and intestinal tract in the control of glucose Homeostasis Hypothalamic regulatory peptides and the regulation of food intake and energy balance: signals or noise?

Williams, G., McKibbin, P. E., & McCarthy, H. D. (1991) · Proceedings of The Nutrition Society · doi:10.1079/pns19910066 · Cited by 27

Viral Mediated Neuropeptide Y Expression in the Rat Paraventricular Nucleus Results in Obesity

Tiesjema, B., la Fleur, S. E., Luijendijk, M. C. M., Brans, M. A. D., Lin, E.-J. D., During, M. J., & Adan, R. A. H. (2007) · Obesity · doi:10.1038/oby.2007.288 · Cited by 26

Cerebrospinal Fluid Neuropeptide Y Levels in Major Depression and Reported Childhood Trauma

Soleimani, L., Oquendo, M. A., Sullivan, G. M., Mathé, A. A., & Mann, J. J. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyu023 · Cited by 26

Differential response to NPY of PVH and dopamine-responsive VMH neurons in overweight rats

Davidowa, H., Li, Y., & Plagemann, A. (2002) · Neuroreport · doi:10.1097/00001756-200208270-00007 · Cited by 26

An Association between Low Levels of Dietary Protein, Elevated NPY Gene Expression in the Basomedial Hypothalamus and Increased Food Intake

White, B. D., Dean, R. G., & Martin, R. J. (1998) · Nutritional Neuroscience · doi:10.1080/1028415x.1998.11747227 · Cited by 26

Anorexia Induced by the Parasitic Nematode, Nippostrongylus brasiliensis: Effects on NPY and CRF Gene Expression in the Rat Hypothalamus

Horbury, S. R., Mercer, J. G., & Chappell, L. H. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00728.x · Cited by 26

Central administration of neuropeptide y induces hypothermia in mice. Possible interaction with central noradrenergic systems

Esteban, J., Chover, A. J., Sánchez, P. A., Micó, J. A., & Gibert‐Rahola, J. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90002-7 · Cited by 26

The (dys)regulation of energy storage in obesity

Levin, B. E., Geary, N., & Lutz, T. A. (2025) · Physiological Reviews · doi:10.1152/physrev.00002.2024 · Cited by 27

Change of the melanocortin system caused by bilateral subthalamic nucleus stimulation in Parkinson’s disease

Sevilla, F. E., Pérez-Navarro, M. J., Muñoz-Pasadas, M., Sáez‐Zea, C., Katati, M. J., Maroto, G. P., Ramírez-Navarro, Á., & Mínguez‐Castellanos, A. (2011) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2010.01469.x · Cited by 26

Molecules affecting hypothalamic control of core body temperature in response to calorie intake

Bartfai, T., & Conti, B. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00184 · Cited by 25

Evidence of Altered Neuropeptide Y Content and Neuropeptide Y1Receptor Gene Expression in the Hypothalamus of Pregnant Transgenic Mice

Oberto, A., Mele, P., Zammaretti, F., Panzica, G., & Eva, C. E. (2003) · Endocrinology · doi:10.1210/en.2003-0197 · Cited by 25

Food intake inhibition and reduction in body weight gain in rats treated with GI264879A, a non-selective NPY-Y1 receptor antagonist

Danielsa, A. J., Chance, W. T., Grizzle, M. K., Heyer, D. O., & Matthews, J. E. (2001) · Peptides · doi:10.1016/s0196-9781(01)00358-8 · Cited by 25

Neuropeptide Y and Somatostatin in the Anterior Piriform Cortex Alter Intake of Amino Acid-deficient Diets

Cummings, S. L., Truong, B. G., & Gietzen, D. W. (1998) · Peptides · doi:10.1016/s0196-9781(97)00468-3 · Cited by 25

Full amino acid sequence of centrally administered NPY required for maximal food intake response

McLaughlin, C. L., Tou, J. S., Rogan, G. J., & Baile, C. A. (1991) · Physiology & Behavior · doi:10.1016/0031-9384(91)90274-r · Cited by 25

Neuropeptide Y: A Novel Peptidergic Signal for the Control of Feeding Behavior

Kalra, S. P., & Kalra, P. S. (1990) · Current topics in neuroendocrinology · doi:10.1007/978-3-642-75837-9_8 · Cited by 25

Appetite and Body Weight Regulation

Vasselli, J. R. (2012) · Wiley eBooks · doi:10.1002/9781394323142.ch8 · Cited by 25

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor

Ando, M., Sato, N., Nagase, T., Nagai, K., Ishikawa, S., Takahashi, H., Ohtake, N., Itô, J., Hirayama, M., Mitobe, Y., et al. (2009) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2009.05.069 · Cited by 24

Methylmercury Affects the Expression of Hypothalamic Neuropeptides That Control Body Weight in C57BL/6J Mice

Ferrer, B., Peres, T. V., dos Santos, A. A., Bornhorst, J., Morcillo, P., Gonçalves, C. L., & Aschner, M. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy052 · Cited by 25

Neurons with diverse phenotypes project from the caudal to the rostral nucleus of the solitary tract

Travers, S. P., Breza, J. M., Harley, J., Zhu, J., & Travers, J. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24501 · Cited by 24

Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?

Henningsen, J. B., & Schéele, C. (2020) · Annual Review of Physiology · doi:10.1146/annurev-physiol-032420-042950 · Cited by 24

Identification of NPY‐induced c‐Fos expression in hypothalamic neurones projecting to the dorsal vagal complex and the lower thoracic spinal cord

Carrasco, M., & Larsen, P. J. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1316 · Cited by 24

Fasting, Leptin Treatment, and Glucose Administration Differentially Regulate Y1 Receptor Gene Expression in the Hypothalamus of Transgenic Mice

Zammaretti, F., Panzica, G., & Eva, C. E. (2001) · Endocrinology · doi:10.1210/endo.142.9.8404 · Cited by 24

An electrophysiological and morphological investigation of the projections of growth hormone-releasing peptide-6-responsive neurons in the rat arcuate nucleus to the median eminence and to the paraventricular nucleus

Honda, K., Bailey, A. R. T., Bull, P. M., Macdonald, L., Dickson, S. L., & Leng, G. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00532-6 · Cited by 24

The effect of obesogenic diets on brain Neuropeptide Y

Gumbs, M. C. R., van den Heuvel, J. K., & la Fleur, S. E. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.04.049 · Cited by 23

Central and peripheral administration of human relaxin‐2 to adult male rats inhibits food intake

McGowan, B. M., MINNION, J. S., Murphy, K. G., White, N. E., Roy, D., Stanley, S. A., Dhillo, W. S., Gardiner, J., Ghatei, M. A., & Bloom, S. R. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01302.x · Cited by 23

Molecular bases of anorexia nervosa, bulimia nervosa and binge eating disorder: shedding light on the darkness

Cuesto, G., Everaerts, C., León, L. G., & Acebes, Á. (2017) · Journal of Neurogenetics · doi:10.1080/01677063.2017.1353092 · Cited by 23

Neuropeptide Y induces gonadotropin-releasing hormone gene expression directly and through conditioned medium from mHypoE-38 NPY neurons

Dhillon, S. S., Gingerich, S., & Belsham, D. D. (2009) · Regulatory Peptides · doi:10.1016/j.regpep.2009.04.005 · Cited by 23

Amphetamine, an appetite suppressant, decreases neuropeptide Y immunoreactivity in rat hypothalamic paraventriculum

Hsieh, Y., Yang, S., & Kuo, D. (2004) · Regulatory Peptides · doi:10.1016/j.regpep.2004.11.007 · Cited by 23

Changes in neuropeptide Y immunoreactivity in the arcuate nucleus during and after food restriction in lactating rats

Abizaid, A. B., Walker, C. D., & Woodside, B. C. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00351-x · Cited by 23

2 Animal models of obesity—theories of aetiology

Proietto, J., & Thorburn, A. W. (1994) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80284-8 · Cited by 23

Role of Melanocortin Signaling in Neuroendocrine and Metabolic Actions of Leptin in Male Rats With Uncontrolled Diabetes

Meek, T. H., Matsen, M. E., Damian, V. M., Cubelo, A., Chua, S. C., & Morton, G. J. (2014) · Endocrinology · doi:10.1210/en.2014-1169 · Cited by 22

Aging and long-term caloric restriction regulate neuropeptide Y receptor subtype densities in the rat brain

Veyrat‐Durebex, C., Quirion, R., Ferland, G., Dumont, Y., & Gaudreau, P. (2013) · Neuropeptides · doi:10.1016/j.npep.2013.01.001 · Cited by 22

BPA Differentially Regulates NPY Expression in Hypothalamic Neurons Through a Mechanism Involving Oxidative Stress

Loganathan, N., McIlwraith, E. K., & Belsham, D. D. (2020) · Endocrinology · doi:10.1210/endocr/bqaa170 · Cited by 22

Lessons from Experimental Disruptions of the Menstrual Cycle in Humans and Monkeys

Williams, N. I. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000084528.13358.67 · Cited by 22

Is decreased appetite for food a physiological consequence of alcohol consumption?

Kokavec, A. (2008) · Appetite · doi:10.1016/j.appet.2008.03.011 · Cited by 22

Neurobiology

Wilding, J. P. H., Widdowson, P. S., & Williams, G. D. (1997) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a011614 · Cited by 22

Evidence for an interaction between neuropeptide Y and the melanocortin-4 receptor on feeding in the rat

Hansen, M. J., & Morris, M. J. (2002) · Neuropharmacology · doi:10.1016/s0028-3908(02)00025-4 · Cited by 22

Increased Hypothalamic Neuropeptide Y Messenger RNA Levels in Two Rat Models of Diabetes

JONES, P. M., Pierson, A. M., Williams, G., Ghatei, M. A., & Bloom, S. R. (1992) · Diabetic Medicine · doi:10.1111/j.1464-5491.1992.tb01719.x · Cited by 22

Effects of N-acetyl- l -cysteine,in vivo, against pathological changes induced by malathion

Lasram, M. M., Douib, I. B., Bouzid, K., Annabi, A. B., Elj, N. E., Dhouib, H., Fazâa, S. E., Abdelmoula, J., & Gharbi, N. (2014) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2014.886003 · Cited by 21

Appetite and Hedonism: Gut Hormones and the Brain

Simpson, K. A., & Bloom, S. R. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.08.001 · Cited by 21

Possible Involvement of Hypothalamic Nucleobindin-2 in Hyperphagic Feeding in Tsumura Suzuki Obese Diabetes Mice

Miyata, S., Yamada, N., & Kawada, T. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00505 · Cited by 21

Sex differences in behavioral and metabolic effects of gene inactivation: The neuropeptide Y and Y receptors in the brain

Eva, C. E., Oberto, A., Longo, A., Palanza, P., & Bertocchi, I. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.020 · Cited by 21

Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study

Katus, U., Villa, I., Ringmets, I., Veidebaum, T., & Harro, J. (2021) · Peptides · doi:10.1016/j.peptides.2021.170524 · Cited by 21

Appetizer administration stimulates food consumption, weight gain and leptin levels in male Wistar rats

Wadikar, D. D., & Premavalli, K. S. (2011) · Appetite · doi:10.1016/j.appet.2011.04.001 · Cited by 21

Physiological endocrine control of energy homeostasis and postprandial blood glucose levels.

Gagliardino, J. J. (2005) · PubMed · Cited by 21

Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform

Rodriguez, M., Audinot, V., Dromaint, S., Macia, C., Lamamy, V., Beauverger, P., Rique, H., Imbert, J., NICOLAS, J. P., Boutin, J. A., et al. (2003) · Biochemical Journal · doi:10.1042/bj20020739 · Cited by 21

Orexins and appetite: The big picture of energy homeostasis gets a little bigger

Schwartz, M. W. (1998) · Nature Medicine · doi:10.1038/nm0498-385 · Cited by 21

Hyperphagia induced by hypoglycemia in rats is independent of leptin and hypothalamic neuropeptide Y (NPY)

Dryden, S. D., Pickavance, L. C., Henderson, L., & Williams, G. (1998) · Peptides · doi:10.1016/s0196-9781(98)00106-5 · Cited by 23

Possible Role of Neuropeptide Y in Experimental Cancer Anorexia

Chance, W. T., Balasubramaniam, A., Sheriff, S., & Fischer, J. E. (1994) · Advances in experimental medicine and biology · doi:10.1007/978-1-4899-0939-8_14 · Cited by 21

Influence of imipramine on neuropeptide Y immunoreactivity in the rat brain

Śmiałowska, M., & Legutko, B. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90366-v · Cited by 21

Reduction in voluntary food intake, but not fasting, stimulates hypothalamic gonadotropin-inhibitory hormone precursor mRNA expression in chicks under heat stress

Bahry, M. A., Yang, H., Tran, P. V., Do, P. H., Han, G., Eltahan, H. M., Chowdhury, V. S., & Furuse, M. (2018) · Neuropeptides · doi:10.1016/j.npep.2018.09.001 · Cited by 20

Increasing association between a neuropeptide Y promoter polymorphism and body mass index during the course of development

Hohmann, S., Buchmann, A. F., Witt, S. H., Rietschel, M., Jennen-Steinmetz, C., Schmidt, M. H., Esser, G., Banaschewski, T., & Laucht, M. (2012) · Pediatric Obesity · doi:10.1111/j.2047-6310.2012.00069.x · Cited by 20

Monoaminergic compensation in the neuropeptide Y deficient mouse brain

Gehlert, D. R., Thompson, L. K., Hemrick-Luecke, S. K., & Shaw, J. (2008) · Neuropeptides · doi:10.1016/j.npep.2007.10.005 · Cited by 20

Current knowledge in the neurophysiologic modulation of obesity

Angelopoulos, N., Goula, A., & Tolis, G. (2005) · Metabolism · doi:10.1016/j.metabol.2005.04.005 · Cited by 20

Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?

Khan, A. M. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00182 · Cited by 22

Intraventricular neuropeptide Y injections stimulate food intake in lean, but not obese Zucker rats

Brief, D. J., Sipols, A. J., & Woods, S. C. (1992) · Physiology & Behavior · doi:10.1016/0031-9384(92)90294-c · Cited by 20

Brain administration of OB protein (leptin) inhibits neuropeptide-Y-induced feeding in ob/ob mice

Smith, F. J., Campfield, L. A., Moschera, J. A., Bailon, P., & Burn, P. (1998) · Regulatory Peptides · doi:10.1016/s0167-0115(98)00099-8 · Cited by 20

The lack of specificity of neuropeptide Y (NPY) antisense oligodeoxynucleotides administered intracerebroventricularly in inhibiting food intake and NPY gene expression in the rat hypothalamus

Dryden, S. D., Pickavance, L., TIDD, D. M., & Williams, G. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1570169 · Cited by 20

Regulation of Pancreatic β-Cell Function by the NPY System

Yang, C.-H., Onda, D.-A., Oakhill, J. S., Scott, J. W., Galić, S., & Loh, K. (2021) · Endocrinology · doi:10.1210/endocr/bqab070 · Cited by 19

Glucagon and the paraventricular hypothalamus: modulation of energy balance

Atrens, D. M., & Menéndez, J. (1993) · Brain Research · doi:10.1016/0006-8993(93)90663-8 · Cited by 19

Obesity genes and the regulation of body fat content

Weigle, D. S., & Kuijper, J. L. (1996) · BioEssays · doi:10.1002/bies.950181105 · Cited by 19

The Regulation of Energy Balance

Seeley, R. J., & Schwartz, M. W. (1997) · Current Directions in Psychological Science · doi:10.1111/1467-8721.ep11512618 · Cited by 19

Elevated Neuropeptide Y Concentrations in the Central Hypothalamus of the Spontaneously Diabetic BB/E Wistar Rat

Williams, G., Lee, Y. C., Ghatei, M. A., Cardoso, H., Ball, J. A., Bone, A. J., BAIRD, J. D., & Bloom, S. R. (1989) · Diabetic Medicine · doi:10.1111/j.1464-5491.1989.tb01236.x · Cited by 19

Further Evidence for a QTL Influencing Body Mass Index on Chromosome 7p from a Genome-wide Scan in Dutch Families

Heijmans, B. T., Beem, A. L., Willemsen, G. A. H. M., Posthuma, D., Slagboom, P. E., & Boomsma, D. I. (2004) · Twin Research · doi:10.1375/136905204323016177 · Cited by 19

Characterization of [Phe13, Tyr19]-MCH analog binding activity to the MCH receptor

Kokkotou, E., Mastaitis, J. W., Qu, D., Hoersch, D., Slieker, L. J., Bonter, K., Tritos, N. A., & Maratos–Flier, E. (2000) · Neuropeptides · doi:10.1054/npep.2000.0821 · Cited by 19

Developmental Aspect of Differences in Hypothalamic Preproneuropeptide Y Messenger Ribonucleic Acid Content in Lean and Genetically Obese Zucker Rats

Sanacora, G., Finkelstein, J. A., & Whitet, J. D. (1992) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1992.tb00179.x · Cited by 19

Effect of Oxytocin on Hunger Discrimination

Head, M. A., Jewett, D. C., Gartner, S. N., Klockars, A., Levine, A. S., & Olszewski, P. K. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00297 · Cited by 18

Postnatal intracerebroventricular exposure to neuropeptide Y causes weight loss in female adult rats

Varma, A., He, J., Weissfeld, L. A., & Devaskar, S. U. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00557.2001 · Cited by 18

Stereological analysis of estrogen receptor expression in the hypothalamic arcuate nucleus of ob/ob and agouti mice

Chakraborty, S., Sachdev, A., Salton, S. R., & Chakraborty, T. R. (2008) · Brain Research · doi:10.1016/j.brainres.2008.04.031 · Cited by 20

Energy Balance, Ingestive Behavior, and Reproductive Success

Schneider, J. E., & Watts, A. G. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50009-3 · Cited by 18

The effect of moxonidine on feeding and body fat in obese Zucker rats: role of hypothalamic NPY neurones

Bing, C., King, P., Pickavance, L. C., Brown, M. J. C., Ziegler, D., Kaan, E. C., & Williams, G. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702494 · Cited by 18

Distribution of cholecystokinin, calcitonin gene‐related peptide, neuropeptide Y, and galanin in the primary gustatory nuclei of the goldfish

Farrell, W., Böttger, B., Ahmadi, F. A., & Finger, T. E. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10317 · Cited by 18

Neuropeptide Y in obese women during treatment with adrenergic modulation drugs.

Zahorska‐Markiewicz, B., Obuchowicz, E., Waluga, M., Tkacz, E., & Herman, Z. S. (2001) · PubMed · Cited by 18

The effect of neuropeptide Y on drinking in mice

Morley, J. E., & Flood, J. F. (1989) · Brain Research · doi:10.1016/0006-8993(89)90151-0 · Cited by 18

Regulation of hypothalamic neuropeptide expression by peripheral metabolism

Berelowitz, M., Bruno, J. F., & White, J. D. (1992) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(92)90101-6 · Cited by 18

Evidence of a role for neuropeptide Y and monoamines in mediating the appetite-suppressive effect of GH

Wang, X., Day, Zhou, Y., Beard, J. L., & VASILATOS-YOUNKEN, R. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1660621 · Cited by 18

Delineating the regulation of energy homeostasis using hypothalamic cell models

Wellhauser, L., Gojska, N. M., & Belsham, D. D. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.09.001 · Cited by 17

Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonists

Sato, N., Jitsuoka, M., Ishikawa, S., Nagai, K., Tsuge, H., Ando, M., Okamoto, O., Iwaasa, H., Gomori, A., Ishihara, A., et al. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.01.101 · Cited by 17

Optimal locations and parameters of gastric electrical stimulation in altering ghrelin and oxytocin in the hypothalamus of rats

Zhang, J., Liu, S.-H., Tang, M., & Chen, J. D. Z. (2008) · Neuroscience Research · doi:10.1016/j.neures.2008.09.004 · Cited by 17

Ventromedial Hypothalamic NPY Y2 Receptor in the Maintenance of Body Weight in Diet-Induced Obesity in Mice

Huang, X., Yu, Y., Li, Y., South, T., Deng, C., & Wang, Q. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9661-5 · Cited by 17

Lipopolysaccharide (LPS) and tumor necrosis factor alpha (TNFα) blunt the response of Neuropeptide Y/Agouti-related peptide (NPY/AgRP) glucose inhibited (GI) neurons to decreased glucose

Hao, L., Sheng, Z., Potian, J. G., Deák, Á., Rohowsky‐Kochan, C., & Routh, V. H. (2016) · Brain Research · doi:10.1016/j.brainres.2016.07.035 · Cited by 19

An Exploratory Study on the Influence of Psychopathological Risk and Impulsivity on BMI and Perceived Quality of Life in Obese Patients

Tambelli, R., Cerniglia, L., Cimino, S., Ballarotto, G., Paciello, M., Lubrano, C., Marchitelli, S., Gnessi, L., & Lenzi, A. (2017) · Nutrients · doi:10.3390/nu9050431 · Cited by 17

An investigation of the neural mechanisms underlying the efficacy of the adjustable gastric band

Stefanidis, A., Forrest, N., Brown, W. A., Dixon, J. B., O’Brien, P. B., Kampe, J., & Oldfield, B. J. (2015) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2015.11.020 · Cited by 17

Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons

Vähätalo, L. H., Ruohonen, S. T., Mäkelä, S., Ailanen, L., Penttinen, A.-M., Stormi, T., Kauko, T., Piscitelli, F., Silvestri, C., Savontaus, E., et al. (2015) · Nutrition and Diabetes · doi:10.1038/nutd.2015.1 · Cited by 18

Dexfenfluramine treatment and hypothalamic neuropeptides in diet-induced obesity in rats

Wilding, J. P. H., Gilbey, S. G., JONES, P. M., Mannan, M. M., Ghatei, M. A., & Bloom, S. R. (1992) · Peptides · doi:10.1016/0196-9781(92)90089-l · Cited by 17

Effect of leptin administration versus re-feeding on hypothalamic neuropeptide gene expression in fasted male rats

McAlister, E. D., & Vugt, D. A. V. (2004) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y04-122 · Cited by 17

Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists

Zimmerman, D. M., Cantrell, B. E., Smith, E. C., Nixon, J. A., Bruns, R. F., Gitter, B. D., Hipskind, P. A., Ornstein, P. L., Zarrinmayeh, H., Britton, T. C., et al. (1998) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(98)00048-1 · Cited by 17

Thermal stability of yeast hydrolysate as a novel anti-obesity material

Park, Y., Kim, J. H., Lee, H.-S., Jung, E. Y., Lee, H., Noh, D. O., & Suh, H. J. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.08.047 · Cited by 16

Orexin A/Hypocretin Modulates Leptin Receptor-Mediated Signaling by Allosteric Modulations Mediated by the Ghrelin GHS-R1A Receptor in Hypothalamic Neurons

Medrano, M., Aguinaga, D., Reyes‐Resina, I., Canela, E. I., Mallol, J., Navarro, G., & Franco, R. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0670-8 · Cited by 16

Gestational 30% and 40% fat diets increase brain GLUT2 and neuropeptide Y immunoreactivity in neonatal Wistar rats

Cerf, M. E., Williams, K. G., van Rooyen, J., Esterhuyse, A. J., Muller, C. J. F., & Louw, J. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.07.226 · Cited by 16

Function of neuropeptide Y and agouti-related protein at weaning: relation to corticosterone, dietary carbohydrate and body weight

LEIBOWITZ, S. F., Sepiashvili, K., Akabayashi, A., Karatayev, O., Davydova, Z., Alexander, J. T., Wang, J., & Chang, G. (2005) · Brain Research · doi:10.1016/j.brainres.2004.12.038 · Cited by 16

Review article: Obesity, waist–hip ratio and hunter–gatherers

Wood, L. (2006) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01070.x · Cited by 16

Past, present and future strategies to study the genetics of body weight regulation

Challis, B. (2002) · Briefings in Functional Genomics and Proteomics · doi:10.1093/bfgp/1.3.290 · Cited by 16

Neuropeptide Y in Relation to Behavior and Psychiatric Disorders

Heilig, M. A. (1993) · Humana Press eBooks · doi:10.1007/978-1-59259-465-8_12 · Cited by 16

Body image changes over the menstrual cycle in normal women

Carr-Nangle, R. E., Johnson, W. G., Bergeron, K. C., & Nangle, D. W. (1994) · International Journal of Eating Disorders · doi:10.1002/1098-108x(199411)16:3 · Cited by 50

Estrogen Reduces Cholecystokinin-Induced c-Fos Expression in the Rat Brain

Flanagan‐Cato, L. M., King, J. L., Blechman, J. G., & O’Brien, M. P. (1998) · Neuroendocrinology · doi:10.1159/000054337 · Cited by 16

Regulatory peptides, the hypothalamus and diabetes

Williams, G., & Bloom, S. R. (1989) · Diabetic Medicine · doi:10.1111/j.1464-5491.1989.tb01213.x · Cited by 16

Neuropeptide Y mediates the short-term hypometabolic effect of estrogen deficiency in mice

Zengin, A., Nguyen, A., Wong, I. P. L., Zhang, L., Enriquez, R., Eisman, J. A., Herzog, H., Baldock, P., & Sainsbury, A. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.71 · Cited by 15

Repeated hypothalamic stimulation with neuropeptide Y increases daily carbohydrate and fat intake and body weight gain in female rats

Stanley, B. G., Anderson, K. C., Grayson, M. H., & LEIBOWITZ, S. F. (1989) · Physiology & Behavior · doi:10.1016/0031-9384(89)90251-5 · Cited by 141

Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism

Raposinho, P., Pierroz, D. D., Broqua, P., White, R. B., Pedrazzini, T., & Aubert, M. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00620-7 · Cited by 143

Neuropeptide Y in normal eating and in genetic and dietary-induced obesity

Beck, B. (2006) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2006.1855 · Cited by 281

Macronutrient type independently of energy intake modulates hypothalamic neuropeptide y in long-evans rats

Beck, B., Stricker‐Krongrad, A., Burlet, A. J., Max, J., Musse, N., Nicolas, J., & Burlet, C. R. (1994) · Brain Research Bulletin · doi:10.1016/0361-9230(94)90002-7 · Cited by 41

Role of hypothalamic neuropeptide Y in feeding and obesity

Gehlert, D. R. (1999) · Neuropeptides · doi:10.1054/npep.1999.0057 · Cited by 209