Cited by 177Dietary Effects on HealthGenetics, Aging, and Longevity in Model OrganismsMemory and Neural Mechanisms

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The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes

STEWART, J, MITCHELL, J, KALANT, N·1989·Neurobiology of Aging

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Abstract

The effect of life-long 60% ad lib food restriction on performance in two tasks involving spatial memory, the eight-arm radial maze and the Morris water maze, was studied in young and aged Fischer 344 rats. Restricted (R) and ad lib (AL) feeding groups were compared at 8, 16, and 24 months of age on both tasks. A 30-month-old R group was also tested in the Morris water maze. In the eight-arm maze, although 24-month-old animals performed more poorly than 8- and 16-month-old animals during the first week of testing, overall accuracy of performance did not vary significantly as a function of age. Twenty-four-month-old animals took longer to make 10 choices than did younger animals, and there was a significant interaction between feeding regimen and age, reflecting the fact that at the two younger ages, R groups performed more quickly than the AL groups. In the Morris water maze, both distance swum and time to find the platform increased with age. Life-long food restriction led to small but significant improvements in performance in the water maze in aged rats. R groups showed evidence for better retention over 24-hour intervals than did AL groups. By 30 months of age, however, R animals showed impaired performance relative to younger R groups. These differential findings on the two tasks, as they were used here, suggest that there was greater impairment with age on the spatial memory task requiring retention of information over long intervals than there was on the task primarily involving working memory within a trial.(ABSTRACT TRUNCATED AT 250 WORDS)

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(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
Place navigation impaired in rats with hippocampal lesions
Morris, R. G. M., Garrud, P., Rawlins, J. N. P., & O'Keefe, J. (1982) · Nature · doi:10.1038/297681a0 · Cited by 6,340
Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.
Barnes, C. A. (1979) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077579 · Cited by 2,088
Remembrance of places passed: Spatial memory in rats.
Olton, D. S., & Samuelson, R. J. (1976) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.2.2.97 · Cited by 1,993
Hippocampal connections and spatial discrimination
Olton, D. S., Walker, J. A., & Gage, F. H. (1978) · Brain Research · doi:10.1016/0006-8993(78)90930-7 · Cited by 840
A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat
Sutherland, R. J., Whishaw, I. Q., & Kolb, B. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90188-2 · Cited by 592
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Barnes, C. A., Nadel, L., & Honig, W. K. (1980) · Canadian Journal of Psychology/Revue Canadienne de Psychologie · doi:10.1037/h0081022 · Cited by 492
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Landfield, P. W., Waymire, J. C., & LYNCH, G. S. (1978) · Science · doi:10.1126/science.715460 · Cited by 491
Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats
Landfield, P. W., McGaugh, J. L., & LYNCH, G. S. (1978) · Brain Research · doi:10.1016/0006-8993(78)90655-8 · Cited by 296

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Tandon, P., Mundy, W. R., Ali, S. F., Nanry, K. P., Rogers, B., & Tilson, H. A. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90254-y · Cited by 31
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Authors: STEWART, J., MITCHELL, J., & KALANT, N.
Affiliations: Concordia University (CA)
Jewish General Hospital (CA)
Venue: Neurobiology of Aging
Publisher: Elsevier BV
Published: 1989-11
Volume: 10
Issue: 6
Pages: 669-675
ISSN: 0197-4580 (ISSN-L)
DOI: 10.1016/0197-4580(89)90003-1
OpenAlex: W2120690437
Cited by: 177
References: 31
Citations by year: 2026: 2 · 2024: 3 · 2023: 2 · 2021: 7 · 2020: 4 · 2019: 3 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 7 · 2014: 2 · 2013: 5 · 2012: 4
FWCI: 2.84
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neurobiology of Aging (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: dietary restriction, spatial memory, aging, eight-arm radial maze, Morris water maze, working memory, long-term retention, age-related cognitive decline, F344 rats, ad libitum feeding
MeSH terms: Aging, Animals, Food Deprivation, Male, Memory, Rats, Inbred F344, Spatial Behavior, Task Performance and Analysis, Time Factors, Rats

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The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes

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