Food restriction enhances visual cortex plasticity in adulthood
Open accessAbstract
Neural circuits display a heightened sensitivity to external stimuli during well-established windows in early postnatal life. After the end of these critical periods, brain plasticity dramatically wanes. The visual system is one of the paradigmatic models for studying experience-dependent plasticity. Here we show that food restriction can be used as a strategy to restore plasticity in the adult visual cortex of rats. A short period of food restriction in adulthood is able both to reinstate ocular dominance plasticity and promote recovery from amblyopia. These effects are accompanied by a reduction of intracortical inhibition without modulation of brain-derived neurotrophic factor expression or extracellular matrix structure. Our results suggest that food restriction could be investigated as a potential way of modulating plasticity.
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In rats with spinal cord lesions, iPlasticity from ChABC or fluoxetine improves recovery.
“In rats, iPlasticity induced either by ChABC or fluoxetine improves recovery from spinal cord lesion189,201.”
From Neuronal plasticity and neurotrophic factors in drug responses (2017) · cites this paper as [201]
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Cellular and Molecular Mechanisms of Pain
Basbaum, A. I., Bautista, D. M., Scherrer, G., & Julius, D. (2009) · Cell · doi:10.1016/j.cell.2009.09.028 · Cited by 4,344 · see citing works
The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
Walf, A. A., & Frye, C. A. (2007) · Nature Protocols · doi:10.1038/nprot.2007.44 · Cited by 3,035 · see citing works
Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex
Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science · doi:10.1126/science.1072699 · Cited by 1,679 · see citing works
Self-citationRecovery of learning and memory is associated with chromatin remodelling
Fischer, A., Sananbenesi, F., Wang, X., Dobbin, M., & Tsai, L.-H. (2007) · Nature · doi:10.1038/nature05772 · Cited by 1,227 · see citing works
Huang, Z. J., Kirkwood, A., Pizzorusso, T., Porciatti, V., Morales, B., Bear, M. F., Maffei, L., & Tonegawa, S. (1999) · Cell · doi:10.1016/s0092-8674(00)81509-3 · Cited by 1,198 · see citing works
Self-citationLee, J., Duan, W., & Mattson, M. P. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01085.x · Cited by 975 · see citing works
Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex
Hensch, T. K., Fagiolini, M., Mataga, N., Stryker, M. P., Baekkeskov, S., & Kash, S. F. (1998) · Science · doi:10.1126/science.282.5393.1504 · Cited by 910 · see citing works
The antidepressant fluoxetine restores plasticity in the adult visual cortex
Vetencourt, J. F. M., Sale, A., Viegi, A., Baroncelli, L., De Pasquale, R., F. O'Leary, O., Castrén, E., & Maffei, L. (2008) · Science · doi:10.1126/science.1150516 · Cited by 890 · see citing works
Self-citationDiamond, D. M., Bennett, M. C., Fleshner, M., & Rose, G. M. (1992) · Hippocampus · doi:10.1002/hipo.450020409 · Cited by 688 · see citing works
Two isoforms of glutamate decarboxylase: why?
Soghomonian, J., & Martin, D. L. (1998) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(98)01270-x · Cited by 643 · see citing works
Rattan, S. I. S. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.03.002 · Cited by 498 · see citing works
Sale, A., Maya Vetencourt, J. F., Medini, P., Cenni, M. C., Baroncelli, L., De Pasquale, R., & Maffei, L. (2007) · Nature Neuroscience · doi:10.1038/nn1899 · Cited by 492 · see citing works
Self-citationCritical periods during sensory development
Berardi, N., Pizzorusso, T., & Maffei, L. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)00047-1 · Cited by 490 · see citing works
Self-citationModification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior
Mattson, M. P., Chan, S. L., & Duan, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00004.2002 · Cited by 438 · see citing works
Corticosteroid effects in the brain: U-shape it
Joëls, M. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.03.007 · Cited by 408 · see citing works
Lee, J., Duan, W., Long, J. M., Ingram, D. K., & Mattson, M. P. (2000) · Journal of Molecular Neuroscience · doi:10.1385/jmn:15:2:99 · Cited by 407 · see citing works
Reducing Intracortical Inhibition in the Adult Visual Cortex Promotes Ocular Dominance Plasticity
Harauzov, A., Spolidoro, M., DiCristo, G., De Pasquale, R., Cancedda, L., Pizzorusso, T., Viegi, A., Berardi, N., & Maffei, L. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2233-09.2010 · Cited by 319 · see citing works
Self-citationModulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine
Kirkwood, A., Rozas, C., Kirkwood, J., Perez, F., & Bear, M. F. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-05-01599.1999 · Cited by 315 · see citing works
Nucleosome displacement in transcription: Figure 1.Preprint
Workman, J. L. (2006) · Genes & Development · doi:10.1101/gad.1435706 · Cited by 303 · see citing works
Mattson, M. P., Duan, W., & Guo, Z. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01586.x · Cited by 288 · see citing works
Sabatino, F., Masoro, E. J., McMahan, C. A., & Kuhn, R. W. (1991) · Journal of Gerontology · doi:10.1093/geronj/46.5.b171 · Cited by 253 · see citing works
Masoro, E. J. (1993) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1993.tb06767.x · Cited by 242 · see citing works
Trachtenberg, J. T., Trepel, C., & Stryker, M. P. (2000) · Science · doi:10.1126/science.287.5460.2029 · Cited by 235 · see citing works
Putignano, E., Lonetti, G., Cancedda, L., Ratto, G., Costa, M., Maffei, L., & Pizzorusso, T. (2007) · Neuron · doi:10.1016/j.neuron.2007.02.007 · Cited by 196 · see citing works
Self-citationCaloric restriction prevents age-related deficits in LTP and in NMDA receptor expression
Eckles-Smith, K., Clayton, D. A., Bickford, P. C., & Browning, M. D. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00088-7 · Cited by 194 · see citing works
Brain‐derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice
Duan, W., Guo, Z., & Mattson, M. P. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00071.x · Cited by 187 · see citing works
Duan, W., Lee, J., Guo, Z., & Mattson, M. P. (2001) · Journal of Molecular Neuroscience · doi:10.1385/jmn:16:1:1 · Cited by 183 · see citing works
STEWART, J., MITCHELL, J., & KALANT, N. (1989) · Neurobiology of Aging · doi:10.1016/0197-4580(89)90003-1 · Cited by 177 · see citing works
Dynamic nucleosomes and gene transcription
Mellor, J. (2006) · Trends in Genetics · doi:10.1016/j.tig.2006.03.008 · Cited by 168 · see citing works
Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex
Baroncelli, L., Sale, A., Viegi, A., Maya‐Vetencourt, J. F., Pasquale, R. D., Baldini, S., & Maffei, L. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.08.009 · Cited by 145 · see citing works
Self-citationVetencourt, J. F. M., Tiraboschi, E., Spolidoro, M., Castrén, E., & Maffei, L. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07488.x · Cited by 138 · see citing works
Self-citationZhao, Y., Sun, H., Lü, J., Li, X., Chen, X., Tao, D., Huang, W., & Huang, B. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01439 · Cited by 125 · see citing works
Ciucci, F., Putignano, E., Baroncelli, L., Landi, S., Berardi, N., & Maffei, L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000475 · Cited by 119 · see citing works
Self-citationGABAergic inhibition in visual cortical plasticity
Sale, A. (2010) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2010.00010 · Cited by 116 · see citing works
Dietary restriction started after spinal cord injury improves functional recovery
Plunet, W. T., Streijger, F., Lam, C. K., Lee, J. H. T., Liu, J., & Tetzlaff, W. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.04.011 · Cited by 116 · see citing works
The glucocorticoid paradox of caloric restriction in slowing brain aging
PATEL, N., & Finch, C. E. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00017-9 · Cited by 115 · see citing works
Plasticity in the adult brain: lessons from the visual system
Spolidoro, M., Sale, A., Berardi, N., & Maffei, L. (2009) · Experimental Brain Research · doi:10.1007/s00221-008-1509-3 · Cited by 111 · see citing works
Self-citationCatalani, A., Alemà, G., Cinque, C., Zuena, A. R., & Casolini, P. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.017 · Cited by 106 · see citing works
de Groote, L., & Linthorst, A. C. E. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.06.030 · Cited by 100 · see citing works
Silingardi, D., Scali, M., Belluomini, G., & Pizzorusso, T. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07261.x · Cited by 96 · see citing works
Idrobo, F., Nandy, K., Mostofsky, D. I., Blatt, L., & Nandy, L. (1987) · Archives of Gerontology and Geriatrics · doi:10.1016/0167-4943(87)90014-8 · Cited by 92 · see citing works
Rozas, C., Frank, H., Heynen, A. J., Morales, B., Bear, M. F., & Kirkwood, A. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-17-06791.2001 · Cited by 90 · see citing works
The Role of Hormesis in Life Extension by Dietary Restriction
Masoro, E. J. (2006) · KARGER eBooks · doi:10.1159/000096552 · Cited by 84 · see citing works
Masoro, E. J. (2001) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.11.s1.s218 · Cited by 81 · see citing works
Long-term potentiation is lost in aged rats but preserved by calorie restriction
Hori, N., Hirotsu, I., Davis, P. J., & Carpenter, D. O. (1992) · Neuroreport · doi:10.1097/00001756-199212000-00013 · Cited by 76 · see citing works
Resilience and vulnerability are dose-dependently related to neonatal stressors in mice
Macrı̀, S., Granstrem, O., Shumilina, M. V., Santos, F. J., Berry, A., Saso, L., & Giovanni Laviola, A. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.07.006 · Cited by 64 · see citing works
Stamp, J. A., Rahia Mashoodh, A., Kampen, J. M. V., & Robertson, H. A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.02.019 · Cited by 56 · see citing works
Han, E.-S., Levin, N. W., Bengani, N., Roberts, J. L., Sun, Y., Karelus, K., & Nelson, J. F. (1995) · The Journals of Gerontology Series A · doi:10.1093/gerona/50a.5.b288 · Cited by 43 · see citing works
Transmitter Release Associated with Long‐term Synaptic Depression in Rat Corticostriatal Slices
Calabresi, P., Fedele, E., Pisani, A., Fontana, G. A., Mercuri, N. B., Bernardi, G., & Raiteri, M. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00710.x · Cited by 40 · see citing works
Casolini, P., Domenici, M. R., Cinque, C., Alemà, G., Chiodi, V., Galluzzo, M., Musumeci, M., Mairesse, J., Zuena, A. R., Matteucci, P., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1074-07.2007 · Cited by 38 · see citing works
Maggio, N., & Segal, M. (2010) · Hippocampus · doi:10.1002/hipo.20893 · Cited by 37 · see citing works
Holliday, R. (2006) · Biogerontology · doi:10.1007/s10522-006-9012-3 · Cited by 21 · see citing works
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Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex
McEwen, B. S., Nasca, C., & Gray, J. D. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.171 · Cited by 1,574 · see citing works
Brain on stress: how the social environment gets under the skin
McEwen, B. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121254109 · Cited by 1,200 · see citing works
The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course
McEwen, B. S., & Morrison, J. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.028 · Cited by 1,079 · see citing works
Social influences on neuroplasticity: stress and interventions to promote well-being
Davidson, R. J., & McEwen, B. S. (2012) · Nature Neuroscience · doi:10.1038/nn.3093 · Cited by 892 · see citing works
Psychobiological allostasis: resistance, resilience and vulnerability
Karatsoreos, I. N., & McEwen, B. S. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.10.005 · Cited by 458 · see citing works
Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
Mattson, M. P. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.08.012 · Cited by 434 · see citing works
Environment and Brain Plasticity: Towards an Endogenous Pharmacotherapy
Sale, A., Berardi, N., & Maffei, L. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2012 · Cited by 402 · see citing works
Self-citationIn pursuit of resilience: stress, epigenetics, and brain plasticity
McEwen, B. S. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13020 · Cited by 299 · see citing works
Recognizing resilience: Learning from the effects of stress on the brain
McEwen, B. S., Gray, J. D., & Nasca, C. (2015) · Neurobiology of Stress · doi:10.1016/j.ynstr.2014.09.001 · Cited by 292 · see citing works
Neuronal plasticity and neurotrophic factors in drug responses
Castrén, E., & Antila, H. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.61 · Cited by 284 · see citing works
Gray, J. D., Milner, T. A., & McEwen, B. S. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.08.034 · Cited by 242 · see citing works
Karatsoreos, I. N., & McEwen, B. S. (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12054 · Cited by 236 · see citing works
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Castrén, E. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.1 · Cited by 190 · see citing works
McEwen, B. S. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.029 · Cited by 171 · see citing works
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Toyoizumi, T., Miyamoto, H., Yazaki-Sugiyama, Y., Atapour, N., Hensch, T. K., & Miller, K. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.07.022 · Cited by 158 · see citing works
New concepts concerning the neural mechanisms of amblyopia and their clinical implications
WONG, A. M. F. (2012) · Canadian Journal of Ophthalmology · doi:10.1016/j.jcjo.2012.05.002 · Cited by 138 · see citing works
Baroncelli, L., Bonaccorsi, J., Milanese, M., Bonifacino, T., Giribaldi, F., Manno, I., Cenni, M. C., Berardi, N., Bonanno, G., Maffei, L., et al. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.02.010 · Cited by 117 · see citing works
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Padamsey, Z., Katsanevaki, D., Dupuy, N., & Rochefort, N. L. (2021) · Neuron · doi:10.1016/j.neuron.2021.10.024 · Cited by 89 · see citing works
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Karatsoreos, I. N., & McEwen, B. S. (2013) · F1000Prime Reports · doi:10.12703/p5-13 · Cited by 84 · see citing works
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Umemori, J., Winkel, F., Didio, G., Llach Pou, M., & Castrén, E. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12683 · Cited by 80 · see citing works
Baroncelli, L., Maffei, L., & Sale, A. (2011) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2011.00025 · Cited by 77 · see citing works
Self-citationBízik, G., Picard, M., Nijjar, R., Tourjman, V., McEwen, B., Lupien, S., & Juster, R. (2013) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000012 · Cited by 70 · see citing works
Neuroplasticity of the visual cortex: in sickness and in health
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Self-citationPopov, A., Denisov, P., Bychkov, M. L., Brazhe, A., Lyukmanova, E. N., Shenkarev, Z. O., Lazareva, N. B., Verkhratsky, A., & Semyanov, A. V. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2406-3 · Cited by 68 · see citing works
IGF-1 Restores Visual Cortex Plasticity in Adult Life by Reducing Local GABA Levels
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Self-citationExperience‐dependent expression of NPAS4 regulates plasticity in adult visual cortex
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Self-citationScheyltjens, I., & Arckens, L. (2016) · Neural Plasticity · doi:10.1155/2016/8723623 · Cited by 60 · see citing works
Visual Cortex Plasticity: A Complex Interplay of Genetic and Environmental Influences
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Зуева, М. В. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00135 · Cited by 39 · see citing works
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Self-citationPinto, J. G. A., Jones, D. G., Williams, C. K., & Murphy, K. M. (2015) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00003 · Cited by 35 · see citing works
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Hugenschmidt, C. E., Leng, X., Lyles, M. F., Michael, L., Dougherty, A. M., Babcock, P., Baker, L. D., Brinkley, T. E., & Nicklas, B. J. (2019) · Obesity · doi:10.1002/oby.22525 · Cited by 22 · see citing works
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Self-citationPoh, E. Z., Harvey, A. R., Makowiecki, K., & Rodger, J. (2018) · eNeuro · doi:10.1523/eneuro.0163-17.2018 · Cited by 20 · see citing works
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Lagas, A. K., Black, J. M., Russell, B. R., Kydd, R. R., & Thompson, B. S. (2019) · Neural Plasticity · doi:10.1155/2019/5857243 · Cited by 19 · see citing works
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McEwen, B. S. (2013) · Science · doi:10.1126/science.1233713 · Cited by 18 · see citing works
Social experience modulates ocular dominance plasticity differentially in adult male and female mice
Balog, J., Matthies, U., Naumann, L., Voget, M., Winter, C., & Lehmann, K. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.08.040 · Cited by 16 · see citing works
Yang, J., Wang, Q., He, F., Ding, Y., Sun, Q., Hua, T., & Xi, M.-M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149004 · Cited by 16 · see citing works
Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry
Berman, Z., Assaf, Y., Tarrasch, R., & Joel, D. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy044 · Cited by 16 · see citing works
Running towards amblyopia recovery
Sansevero, G., Torelli, C., Mazziotti, R. M., Consorti, A., Pizzorusso, T., Berardi, N., & Sale, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-69630-7 · Cited by 16 · see citing works
Restani, L., & Caleo, M. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2016.00086 · Cited by 16 · see citing works
Refinement but Not Maintenance of Visual Receptive Fields Is Independent of Visual Experience
Balmer, T. S., & Pallas, S. L. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht281 · Cited by 14 · see citing works
Smith, M. R., Glicksberg, B. S., Li, L., Chen, R., Morishita, H., & Dudley, J. T. (2017) · Pacific Symposium on Biocomputing (PSB) · doi:10.1142/9789813235533_0007 · Cited by 13 · see citing works
Huang, S. S. Y., Makhlouf, M., AbouMoussa, E. H., Segura, M. L. R. T., Mathew, L. S., Wang, K., Leung, M. C., Chaussabel, D., Logan, D. W., Scialdone, A., et al. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101038 · Cited by 11 · see citing works
Effects of Stress Throughout the Lifespan on the Brain and Behavior
Nasca, C., Davis, E. P., Bigio, B., Sandi, C., & McEwen, B. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00111-5 · Cited by 10 · see citing works
Skirzewski, M., Molotchnikoff, S., Hernandez, L. F., & Maya‐Vetencourt, J. F. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.806376 · Cited by 9 · see citing works
Self-citationEffect of fasting on short‐term visual plasticity in adult humans
Animali, S., Steinwurzel, C., Dardano, A., Sancho‐Bornez, V., Prato, S. D., Morrone, M. C., Daniele, G., & Binda, P. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15873 · Cited by 9 · see citing works
Resilience of the Brain and Body
McEwen, B. S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813146-6.00002-3 · Cited by 9 · see citing works
Visual deprivation independent shift of ocular dominance induced by cross-modal plasticity
Teichert, M., Isstas, M., Liebmann, L., Hübner, C. A., Wieske, F., Winter, C., Lehmann, K., & Bolz, J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213616 · Cited by 9 · see citing works
Long-term intermittent feeding restores impaired GR signaling in the hippocampus of aged rat
Tešić, V., Perović, M., Lazić, D., Kojić, S., Smiljanić, K., Ruždijić, S., Rakić, L., & Kanazir, S. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.01.013 · Cited by 8 · see citing works
Bi, A.-L., Zhang, Y., Lu, Z.-Y., Tang, H., Zhang, X., Zhang, Z., Li, B., Guo, D., Gong, S., Li, Q., et al. (2021) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.62.7.20 · Cited by 6 · see citing works
Social hierarchy regulates ocular dominance plasticity in adult male mice
Balog, J., Hintz, F., Isstas, M., Teichert, M., Winter, C., & Lehmann, K. (2019) · Brain Structure and Function · doi:10.1007/s00429-019-01959-w · Cited by 5 · see citing works
The Brain on Stress: The Good and the Bad
McEwen, B. S. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1056-4_1 · Cited by 5 · see citing works
Khlaifia, A., Matias, I., Cota, D., & Tell, F. (2017) · The Journal of Physiology · doi:10.1113/jp273484 · Cited by 4 · see citing works
Teichert, M., Isstas, M., Wieske, F., Winter, C., & Bolz, J. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.09.040 · Cited by 4 · see citing works
Evaluation of nutritional status in children with amblyopia
Subasi, S., Altıntaş, Ö., Mercan, S., Çizmecioğlu, F., Toprak, M., & Emre, E. (2019) · Arquivos Brasileiros de Oftalmologia · doi:10.5935/0004-2749.20190022 · Cited by 4 · see citing works
Park, S. B., & Lür, G. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100660 · Cited by 3 · see citing works
Non-invasive light flickering reinstates visual plasticity in adult mice via lipocalin 2
Ma, C., Wang, Z., Wu, W., Ma, X., Wang, L., Zhang, X., Chen, W., Kuang, X., Li, Y., Miao, Y., et al. (2025) · BMC Biology · doi:10.1186/s12915-025-02360-2 · Cited by 3 · see citing works
McEwen, B. S. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-398270-4.00034-3 · Cited by 2 · see citing works
Neuroproteomics applied to the study of visual cortex plasticity
Rossi, F., & Pizzorusso, T. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.04.021 · Cited by 2 · see citing works
The changing face of Amblyopia
Thompson, B. S. (2012) · Canadian Journal of Ophthalmology · doi:10.1016/j.jcjo.2012.08.009 · Cited by 2 · see citing works
Basic mechanisms of, and treatment targets for, stress-related disorders
McEwen, B. S. (2020) · doi:10.1093/med/9780198713005.003.0079 · Cited by 2 · see citing works
Inhibition of Cdk5 in PV Neurons Reactivates Experience-Dependent Plasticity in Adult Visual Cortex
Zhang, X., Tang, H., Li, S., Liu, Y., Wu, W., Li, Y., Ma, C., Ma, X., Chen, L., & Yang, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010186 · Cited by 1 · see citing works
Insights into Visual Cortex Plasticity: Interaction Between Genes and Sensory Experience
Fernando, J. B., & Caleo, M. (2012) · InTech eBooks · doi:10.5772/50721 · Cited by 1 · see citing works
Meaney, M. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85654-6.00059-9 · Cited by 1 · see citing works
Scarlatti, F. (2023) · doi:10.31234/osf.io/gfuet · Cited by 1 · see citing works
Pengehadan Kalori, Fungsi Kognitif dan Penuaan: Peranan terhadap Sistem Biologi
Meramat, A. A., Rajab, N. F., Shahar, S. N., & Sharif, R. (2017) · Sains Malaysiana · doi:10.17576/jsm-2017-4609-35
(2014) · Society for Neuroscience eBooks · doi:10.1523/hon.008005
Mechanisms of Experience-dependent Prevention of Plasticity in Visual Circuits
Balmer, T. S. (2022) · Digital Archive @ GSU · doi:10.57709/5814205
Oruç, D., & Işık, S. (2025) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.1571616
Dapueto, A., Hayek, E., Acuña, A., Pannunzio, B., Gómez‐Sena, L., & Rossi, F. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.01.003
Arsène, S., Audren, F., Benso-Layoun, C., Quoc, E. B., Denis, D., Matonti, F., Péchereau, A., Sekfali, R., & ZANIN, E. (2013) · Elsevier eBooks · doi:10.1016/b978-2-294-73838-8.50015-5
- Authors
- Spolidoro, M., Baroncelli, L., Putignano, E., Maya-Vetencourt, J. F., Viegi, A., & Maffei, L.
- Affiliations
- Neuroscience Institute (IT)
- Scuola Normale Superiore (IT)
- Corresponding author
- Spolidoro, Maria
- Venue
- Nature Communications
- Published
- 2011-05-17
- Volume
- 2
- Issue
- 1
- Pages
- 320-320
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2037043502
- Cited by
- 91
- References
- 52
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 5 · 2019: 7 · 2018: 8 · 2017: 5 · 2016: 8 · 2015: 6 · 2014: 7 · 2013: 13 · 2012: 14
- FWCI
- 5.84
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Communications (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- CINECA IRIS Institutial research information system (University of Pisa) (submittedVersion)
- Scuola Normale Superiore di Pisa (submittedVersion)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- dietary restriction, visual cortex plasticity, ocular dominance plasticity, intracortical inhibition, brain-derived neurotrophic factor, extracellular matrix, experience-dependent plasticity, critical period, caloric restriction, adult neuroplasticity
- MeSH terms
- Age Factors, Amblyopia, Animals, Disease Models, Animal, Female, Humans, Male, Neuronal Plasticity, Visual Cortex, Vision, Monocular, Rats, Long-Evans, Dominance, Ocular, Caloric Restriction, Rats
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