Cited by 34Lipid metabolism and biosynthesisSteroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Alterations in Rat Lipid Metabolism Following Ecdysterone Treatment

Catalán, R.E., Martinez, A.M., Aragones, M.D., Miguel, B.G., Robles, A., Godoy, J.E.·1985·Comparative Biochemistry and Physiology Part B Comparative Biochemistry

Abstract

The influence of ecdysterone on the lipid metabolism in liver and adipose tissue from rat was investigated using 14C-acetate and 32P-orthophosphate as precursors. Ecdysterone produced an increase in 14C-acetate incorporation into triglycerides. A concomitant decrease in free fatty acids and diglycerides was observed. The effect of ecdysterone on triglyceride lipase activity was investigated and a significant decrease was found. Ecdysterone produced a significant increase in the specific activity of phosphatidylethanolamine and phosphatidylserine in liver. On the contrary, the specific activity of phosphatidylcholine was reduced. In adipose tissue, the most evident effect observed was the increase of specific activity of phosphatidylcholine. These results contribute to knowledge of the heterophylic action of ecdysterone.

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Crossref · 10.1016/0305-0491(85)90403-1

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17 of 17 references verified0 citation errors · 0 not checkable

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Authors
Catalán, R. E., Martinez, A. M., Aragones, M. D., Miguel, B. G., Robles, A., & Godoy, J. E.
Affiliations
Consejo Superior de Investigaciones Científicas (ES)
Corresponding author
Catalán, R.E.
Venue
Comparative Biochemistry and Physiology Part B Comparative Biochemistry
Publisher
Elsevier BV
Published
1985
Volume
81
Issue
3
Pages
771-775
ISSN
0305-0491 (ISSN-L)
OpenAlex
W2045291424
Cited by
34
References
16
Citations by year
2025: 2 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
FWCI
0.22
Type
journal article
Language
en
Open access
closed
Locations
  • Comparative Biochemistry and Physiology Part B Comparative Biochemistry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
  • Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
Keywords
20-hydroxyecdysone, lipid metabolism, liver, adipose tissue, triglyceride synthesis, triacylglycerol lipase, free fatty acids, diacylglycerol, phospholipids, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, insect hormones
MeSH terms
Acetates, Adipose Tissue, Animals, Carbon Radioisotopes, Diglycerides, Ecdysterone, Fatty Acids, Nonesterified, Liver, Male, Phosphates, Phospholipids, Phosphorus Radioisotopes, Protein Kinases, Rats, Inbred Strains, Triglycerides, Acetic Acid, Lipid Metabolism, Rats

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