Cited by 153Memory and Neural MechanismsStress Responses and CortisolNeuroscience and Neuropharmacology Research

Hippocampal pathway to the amygdala and stress ulcer development.

Henke, Peter G.·1990·Brain Research Bulletin

Abstract

The objective of the first study was to localize the reported aggravation of stress ulcers found after large bilateral hippocampal lesions in rats. Lesions in the ventral hippocampus produced a similar increase in the severity of gastric erosions after cold-restraint, as was seen after large bilateral lesions. Dorsal hippocampal damage produced no differential effects. In the second experiment, high-frequency electrical stimulation of the ventral CA1 region of the hippocampus, a procedure known to induce long-term potentiation, increased the evoked potentials in the lateral central nucleus of the amygdala, and in adjacent parts of the lateral and basolateral nuclei. The increase in the efficacy of synaptic transmission in this pathway attenuated stress ulcer development. It was concluded that the ventral hippocampus is part of a coping system, and a strengthening of synaptic connections with the central amygdala increases the coping ability of rats under stress conditions.

Integrity signals

Registry

Crossref · 10.1016/0361-9230(90)90044-z

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Henke, P. G.
Affiliations
St. Francis Xavier University (CA)
Corresponding author
Henke, Peter G.
Venue
Brain Research Bulletin
Publisher
Elsevier BV
Published
1990-11
Volume
25
Issue
5
Pages
691-695
ISSN
0361-9230 (ISSN-L)
OpenAlex
W2027122202
Cited by
153
References
26
Citations by year
2026: 5 · 2025: 9 · 2024: 11 · 2023: 7 · 2022: 9 · 2021: 14 · 2020: 9 · 2019: 13 · 2018: 8 · 2017: 9 · 2016: 9 · 2015: 4 · 2014: 6 · 2013: 7 · 2012: 8
FWCI
1.20
Type
journal article
Language
en
Open access
closed
Locations
  • Brain Research Bulletin (publishedVersion)
  • PubMed (publishedVersion)
Funders
Natural Sciences and Engineering Research Council of Canada
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
stress ulcer, gastric erosions, ventral hippocampus, central amygdala, dorsal hippocampus, hippocampal lesions, cold restraint stress, long-term potentiation, synaptic transmission, coping, stress response
MeSH terms
Amygdala, Animals, Electric Stimulation, Evoked Potentials, Hippocampus, Male, Neural Pathways, Rats, Inbred Strains, Stomach Ulcer, Stress, Physiological, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review