Different effects of prolonged exercise on the right and left ventricles
Open accessAbstract
To examine the functional consequences of the greater increase in right ventricular work with exercise, the effects of prolonged exercise on the right and left heart chambers were compared in 41 athletes before, at the finish (13 min) and after recovery (28 h) from the Hawaii Ironman Triathlon (3.9 km swim, 180.2 km bike ride, 42.2 km run). Two-dimensional and Doppler echocardiograms were analyzed for left and right atrial and ventricular areas at end-diastole and end-systole, right and left ventricular inflow velocities and mitral and tricuspid regurgitation. After exercise, left ventricular and left and right atrial sizes were reduced, whereas right ventricular size increased (diastole: 21.4 to 24.2 cm2; systole: 15.8 to 18.2 cm2; p less than 0.01). The emptying fraction of all chambers was unchanged. Left but not right ventricular inflow showed an increase in peak velocity of rapid filling, whereas both atrial systolic velocities increased (26 to 38 cm/s tricuspid; 38 to 54 cm/s mitral; both p less than 0.01). Overall, the right ventricular early to atrial velocity ratio was reduced after exercise (1.56 to 1.17; p less than 0.05) and the left ventricular pattern was unchanged. The prevalence of tricuspid regurgitation was statistically unchanged (86% to 52%), although that of mitral regurgitation was greatly reduced (76% to 0%). Changes in all variables returned toward prerace values during recovery. Thus, in highly trained athletes, prolonged exercise causes differing responses of the right and left ventricles. These differences may be due to changes in right ventricular function, shape or compliance.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Right ventricular function may be more profoundly affected by intense endurance exercise than left ventricular function.
“However, right ventricular (RV) function may be more profoundly affected by intense endurance exercise 6 -10”
From Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes (2012) · cites this paper as [10]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Color Doppler assessment of mitral regurgitation with orthogonal planes.
Helmcke, F. R., Nanda, N. C., Hsiung, M. C., Soto, B., Adey, C. K., Goyal, R. G., & Gatewood, R. P. (1987) · Circulation · doi:10.1161/01.cir.75.1.175 · Cited by 1,219 · see citing works
Assessment of right ventricular function using two-dimensional echocardiography
Kaul, S., Tei, C., Hopkins, J. M., & Shah, P. M. (1984) · American Heart Journal · doi:10.1016/0002-8703(84)90095-4 · Cited by 1,038 · see citing works
Comparing the Means of Several Groups
Godfrey, K. (1985) · New England Journal of Medicine · doi:10.1056/nejm198512053132305 · Cited by 740 · see citing works
Preload dependence of doppler-derived indexes of left ventricular diastolic function in humans
Choong, C. Y. P., Herrmann, H. C., Weyman, A. E., & Fifer, M. A. (1987) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(87)80273-5 · Cited by 623 · see citing works
Rokey, R., Kuo, L. C., Zoghbi, W. A., Limacher, M. C., & Quiñones, M. A. (1985) · Circulation · doi:10.1161/01.cir.71.3.543 · Cited by 529 · see citing works
Spirito, P., Maron, B. J., & Bonow, R. O. (1986) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(86)80461-2 · Cited by 424 · see citing works
Miyatake, K., Okamoto, M., Kinoshita, N., Owa, M., Nakasone, I., Sakakibara, H., & Nimura, Y. (1984) · The American Journal of Cardiology · doi:10.1016/0002-9149(84)90035-3 · Cited by 390 · see citing works
Determination of right atrial and right ventricular size by two-dimensional echocardiography.
Bommer, W. J., Weinert, L., Neumann, A., Neef, J., Mason, D. T., & DeMaria, A. N. (1979) · Circulation · doi:10.1161/01.cir.60.1.91 · Cited by 282 · see citing works
Cardiac fatigue after prolonged exercise.
Douglas, P. S., OʼToole, M. L., Hiller, W. D. B., Hackney, K., & Reichek, N. (1987) · Circulation · doi:10.1161/01.cir.76.6.1206 · Cited by 264 · see citing works
Self-citationThe effect of exercise on the cardiac output and circulatory dynamics of normal subjects.
Donald, K. W., BISHOP, J. M., Cumming, G., & Wade, O. L. (1955) · PubMed · Cited by 255 · see citing works
Plasma volume changes following exercise and thermal dehydration.
COSTILL, D. L., & Fink, W. J. (1974) · Journal of Applied Physiology · doi:10.1152/jappl.1974.37.4.521 · Cited by 236 · see citing works
Circulatory response to prolonged severe exercise
Saltin, B., & Stenberg, J. (1964) · Journal of Applied Physiology · doi:10.1152/jappl.1964.19.5.833 · Cited by 199 · see citing works
Diastolic filling dynamics in patients with aortic stenosis.
Murakami, T., Hess, O. M., Gage, J. E., Grimm, J., & Krayenbuehl, H. P. (1986) · Circulation · doi:10.1161/01.cir.73.6.1162 · Cited by 139 · see citing works
Invariant total heart volume in the intact thorax
Hoffman, E. A., & Ritman, E. L. (1985) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1985.249.4.h883 · Cited by 135 · see citing works
Simple Linear Regression in Medical Research
Godfrey, K. (1985) · New England Journal of Medicine · doi:10.1056/nejm198512263132604 · Cited by 134 · see citing works
Evidence of impaired left ventricular performance after an uninterrupted competitive 24 hour run.
Niemelä, K. O., Palatsi, I., Ikäheimo, M. J., Takkunen, J. T., & Vuori, J. J. (1984) · Circulation · doi:10.1161/01.cir.70.3.350 · Cited by 117 · see citing works
Pulsed doppler echocardiographic detection of right-sided valve regurgitation
Waggoner, A. D., Quiñones, M. A., Young, J. B., Brandon, T. A., Shah, A. A., Verani, M. S., & Miller, R. R. (1981) · The American Journal of Cardiology · doi:10.1016/0002-9149(81)90398-2 · Cited by 115 · see citing works
Determinants of ventricular septal motion. Influence of relative right and left ventricular size.
Pearlman, A. S., Clark, C. E., Henry, W. L., Morganroth, J., Itscoitz, S. B., & Epstein, S. E. (1976) · Circulation · doi:10.1161/01.cir.54.1.83 · Cited by 101 · see citing works
Left ventricular dysfunction after prolonged strenuous exercise in healthy subjects
Seals, D. R., Rogers, M. A., Hagberg, J. M., Yamamoto, C., Cryer, P. E., & Ehsani, A. A. (1988) · The American Journal of Cardiology · doi:10.1016/0002-9149(88)90362-1 · Cited by 81 · see citing works
Normal Values for Pulmonary Hemodynamics at Rest and during Exercise in Man
Gurtner, H. P., Walser, P., & F�ssler, B. (2015) · Progress in respiratory research/Progress in research in emphysema and chronic bronchitis/Progress in respiration research · doi:10.1159/000398202 · Cited by 77 · see citing works
The interventricular septum in health and disease
Kaul, S. (1986) · American Heart Journal · doi:10.1016/0002-8703(86)90523-5 · Cited by 68 · see citing works
Effect of brief and prolonged exercise on left ventricular function
Upton, M. T., Rerych, S. K., Roeback, J. R., Newman, G. E., Douglas, J. M., Wallace, A. G., & Jones, R. H. (1980) · The American Journal of Cardiology · doi:10.1016/0002-9149(80)90473-7 · Cited by 50 · see citing works
Echocardiographic assessment of left ventricular performance before and after marathon running
Perrault, H., Péronnet, F., Lebeau, R., & Nadeau, R. A. (1986) · American Heart Journal · doi:10.1016/0002-8703(86)90316-9 · Cited by 42 · see citing works
Trowitzsch, E., Colan, S. D., & Sanders, S. P. (1985) · The American Journal of Cardiology · doi:10.1016/0002-9149(85)90654-x · Cited by 32 · see citing works
The Lesser Circulation during Exercise in Healthy Subjects
Staněk, V., Widimsk�, J., Degr�, S., & Dénolin, H. (2015) · Progress in respiratory research/Progress in research in emphysema and chronic bronchitis/Progress in respiration research · doi:10.1159/000398156 · Cited by 16 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Stanek v, Jebavy P. Hurych J, Widimsky J. Central haemodynamics . . . . ounng supme exercise and pulmonary artery occulsion in normal sub- jects. Bull Physiopath Resp 1973;9:1203-17.
- Miyatake K, Okamoto M, Kinosbita N, et al. Augmentation of atria! contribution of left ventricular inflow with aging as assessed by intracar- metry. Am J Cardiol 1984;53:586-9.
Cited by
Sorted by citations
Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes
La Gerche, A., Burns, A. T., Mooney, D. J., Inder, W. J., Taylor, A. J., Bogaert, J., MacIsaac, A. I., Heidbüchel, H., & Prior, D. L. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr397 · Cited by 776 · see citing works
James, C. A., Bhonsale, A., Tichnell, C., Murray, B., Russell, S. D., Tandri, H., Tedford, R. J., Judge, D. P., & Calkins, H. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.06.033 · Cited by 710 · see citing works
Exercise as Cardiovascular Therapy
Shephard, R. J., & Balady, G. J. (1999) · Circulation · doi:10.1161/01.cir.99.7.963 · Cited by 572 · see citing works
Cardiac arrhythmogenic remodeling in a rat model of long-term intensive exercise training
Benito, B., Gay-Jordi, G., Serrano-Mollar, A., Guasch, E., Shi, Y., Tardif, J.-C., Brugada, J., Nattel, S., & Mont, L. (2011) · Circulation · doi:10.1161/circulationaha.110.938282 · Cited by 478 · see citing works
Franklin, B. A., Thompson, P. D., Al-Zaiti, S. S., Albert, C. M., Hivert, M.-F., Levine, B. D., Lobelo, F., Madan, K., Sharrief, A. Z., Eijsvogels, T. M. H., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000749 · Cited by 410 · see citing works
Spirito, P., Pelliccia, A., Proschan, M. A., Granata, M., Spataro, A., Bellone, P., Caselli, G., Biffi, A., Vecchio, C., & Maron, B. J. (1994) · The American Journal of Cardiology · doi:10.1016/0002-9149(94)90439-1 · Cited by 411 · see citing works
Heidbüchel, H. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00282-3 · Cited by 395 · see citing works
Galderisi, M., Cardim, N. M., D’Andrea, A., Bruder, O., Cosyns, B., Davin, L., Donal, E., Edvardsen, T., Freitas, A., Habib, G., et al. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeu323 · Cited by 258 · see citing works
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy: A Review
Marcus, G. M., & Fontaine, G. H. (1995) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1995.tb06971.x · Cited by 255 · see citing works
Are There Deleterious Cardiac Effects of Acute and Chronic Endurance Exercise?
Eijsvogels, T. M. H., Fernández, A. B., & Thompson, P. D. (2015) · Physiological Reviews · doi:10.1152/physrev.00029.2014 · Cited by 229 · see citing works
Sawant, A. C., Bhonsale, A., te Riele, A. S. J. M., Tichnell, C., Murray, B., Russell, S. D., Tandri, H., Tedford, R. J., Judge, D. P., Calkins, H., et al. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001471 · Cited by 221 · see citing works
Gerche, A. L., Claessen, G., Dymarkowski, S., Voigt, J., Buck, F. D., Vanhees, L., Droogné, W., Cleemput, J. V., Claus, P., & Heidbüchel, H. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv202 · Cited by 202 · see citing works
Acute cardiac effects of marathon running
Trivax, J. E., Franklin, B. A., Goldstein, J. A., Chinnaiyan, K. M., Gallagher, M. J., deJong, A. T., Colar, J. M., Haines, D. E., & McCullough, P. A. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01151.2009 · Cited by 229 · see citing works
Range of right heart measurements in top-level athletes: The training impact
D’Andrea, A., Riegler, L., Golia, E., Cocchia, R., Scarafile, R., Salerno, G., Pezzullo, E., Nunziata, L., Citro, R., Cuomo, S., et al. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.06.058 · Cited by 180 · see citing works
Pulmonary Circulation at Exercise
Naeije, R., & Chesler, N. C. (2012) · Comprehensive physiology · doi:10.1002/cphy.c100091 · Cited by 170 · see citing works
Persistent and reversible cardiac dysfunction among amateur marathon runners
Neilan, T. G., Yoerger, D. M., Douglas, P. S., Marshall, J. E., Halpern, E. F., Lawlor, D., Picard, M. H., & Wood, M. J. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi813 · Cited by 206 · see citing works
Self-citationRelation of Biomarkers and Cardiac Magnetic Resonance Imaging After Marathon Running
Mousavi, N., Czarnecki, A., Kumar, K., Fallah-Rad, N., Lytwyn, M., Han, S.-Y., Francis, A., Walker, J. R., Kirkpatrick, I. D. C., Neilan, T. G., et al. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.01.294 · Cited by 190 · see citing works
Applied Physiology of a Triathlon
TOOLE, M. L. O., Douglas, P. S., & Hiller, W. D. B. (1989) · Sports Medicine · doi:10.2165/00007256-198908040-00002 · Cited by 164 · see citing works
Self-citationDilatation and Dysfunction of the Right Ventricle Immediately After Ultraendurance Exercise
Oxborough, D., Shave, R., Warburton, D. E. R., Williams, K., Oxborough, A., Charlesworth, S. A., Foulds, H. J. A., Hoffman, M. D., Birch, K. M., & George, K. (2011) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.110.961938 · Cited by 161 · see citing works
Ector, J., Ganame, J., van der Merwe, N., Adriaenssens, B., Pison, L., Willems, R., Gewillig, M., & Heidbuchel, H. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehl468 · Cited by 155 · see citing works
Ventricular arrhythmias associated with long-term endurance sports: what is the evidence?
Heidbüchel, H., Prior, D., & Gerche, A. L. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091162 · Cited by 150 · see citing works
Left Ventricular Function Immediately following Prolonged Exercise
Middleton, N., Shave, R., George, K., Whyte, G. P., Hart, E. C., & Atkinson, G. (2006) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000210203.10200.12 · Cited by 148 · see citing works
Caso, P., D’Andrea, A., Galderisi, M., Liccardo, B., Severino, S., Simone, L. D., Izzo, A., D’Andrea, L., & Mininni, N. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00709-8 · Cited by 149 · see citing works
Gerche, A. L., Burns, A., D’hooge, J., MacIsaac, A. I., Heidbüchel, H., & Prior, D. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2011.11.023 · Cited by 148 · see citing works
Applied Physiology of Triathlon
OʼToole, M. L., & Douglas, P. S. (1995) · Sports Medicine · doi:10.2165/00007256-199519040-00003 · Cited by 148 · see citing works
Self-citationD’Andrea, A., Limongelli, G., Caso, P., Sarubbi, B., Pietra, A. D., Brancaccio, P., Cice, G., Scherillo, M., Limongelli, F. M., & Calabrò, R. (2002) · International Journal of Cardiology · doi:10.1016/s0167-5273(02)00194-8 · Cited by 131 · see citing works
Can Intensive Exercise Harm the Heart?
Gerche, A. L., & Heidbüchel, H. (2014) · Circulation · doi:10.1161/circulationaha.114.008141 · Cited by 132 · see citing works
Exercise and the Risk of Sudden Cardiac Death
Corrado, D., Migliore, F., Basso, C., & Thiene, G. (2006) · Herz · doi:10.1007/s00059-006-2885-8 · Cited by 128 · see citing works
What Limits Cardiac Performance during Exercise in Normal Subjects and in Healthy Fontan Patients?
Gerche, A. L., & Gewillig, M. H. M. L. (2010) · International Journal of Pediatrics · doi:10.1155/2010/791291 · Cited by 114 · see citing works
“Exercise‐Induced Cardiac Fatigue”—A Review of the Echocardiographic Literature
Oxborough, D., Birch, K. M., Shave, R., & George, K. (2010) · Echocardiography · doi:10.1111/j.1540-8175.2010.01251.x · Cited by 111 · see citing works
Does the Human Heart Fatigue Subsequent to Prolonged Exercise?
Dawson, E. A., George, K., Shave, R., Whyte, G. P., & Ball, D. R. (2003) · Sports Medicine · doi:10.2165/00007256-200333050-00003 · Cited by 108 · see citing works
Elliott, A. D., & Gerche, A. L. (2014) · British Journal of Sports Medicine · doi:10.1136/bjsports-2014-093895 · Cited by 104 · see citing works
Left Ventricular Myocardial Velocities and Deformation Indexes in Top-Level Athletes
D’Andrea, A., Cocchia, R., Riegler, L., Scarafile, R., Salerno, G., Gravino, R., Golia, E., Pezzullo, E., Citro, R., Limongelli, G., et al. (2010) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2010.09.020 · Cited by 103 · see citing works
Transient Right but Not Left Ventricular Dysfunction After Strenuous Exercise at High Altitude
Dávila‐Román, V. G., Guest, T. M., Tuteur, P. G., Rowe, W. J., Ladenson, J. H., & Jaffe, A. S. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00179-4 · Cited by 99 · see citing works
Athlete's Heart: The Potential for Multimodality Imaging to Address the Critical Remaining Questions
Gerche, A. L., Taylor, A. J., & Prior, D. (2009) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2008.12.011 · Cited by 95 · see citing works
D’Andrea, A., Riegler, L., Morra, S., Scarafile, R., Salerno, G., Cocchia, R., Golia, E., Martone, F., Salvo, G. D., Limongelli, G., et al. (2012) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2012.07.020 · Cited by 90 · see citing works
Right Ventricular Fatigue Developing during Endurance Exercise
Claessen, G., Claus, P., Ghysels, S., Vermeersch, P., Dymarkowski, S., Gerche, A. L., & Heidbüchel, H. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000282 · Cited by 86 · see citing works
D’Ascenzi, F., Pelliccia, A., Solari, M., Piu, P., Loiacono, F., Anselmi, F., Caselli, S., Focardi, M., Bonifazi, M., & Mondillo, S. (2017) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2017.06.013 · Cited by 85 · see citing works
La Gerche, A., Inder, W. J., Roberts, T. J., Brosnan, M. J., Heidbuchel, H., & Prior, D. L. (2015) · PLOS ONE · doi:10.1371/journal.pone.0130031 · Cited by 80 · see citing works
Mocchegiani, R., Badano, L. P., Lestuzzi, C., Nicolosi, G. L., & Zanuttini, D. (1995) · The American Journal of Cardiology · doi:10.1016/s0002-9149(99)80266-5 · Cited by 79 · see citing works
Cardiovascular damage resulting from chronic excessive endurance exercise.
Patil, H., O’Keefe, J. H., Lavie, C. J., Magalski, A., Vogel, R. A., & McCullough, P. A. (2012) · Europe PMC (PubMed Central) · Cited by 78 · see citing works
D’Andrea, A., Caso, P., Bossone, E., Scarafile, R., Riegler, L., Salvo, G. D., Gravino, R., Cocchia, R., Castaldo, F., Salerno, G., et al. (2010) · European Journal of Echocardiography · doi:10.1093/ejechocard/jeq007 · Cited by 77 · see citing works
Right ventricular remodelling induced by exercise training in competitive athletes
D’Ascenzi, F., Pelliccia, A., Corrado, D., Cameli, M., Curci, V., Alvino, F., Natali, B. M., Focardi, M., Bonifazi, M., & Mondillo, S. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jev155 · Cited by 75 · see citing works
Myocardial Adaptation to Short-term High-intensity Exercise in Highly Trained Athletes
Neilan, T. G., Ton-Nu, T.-T., Jassal, D. S., Popović, Z., Douglas, P. S., Halpern, E. F., Marshall, J. E., Thomas, J. D., Picard, M. H., Yoerger, D. M., et al. (2006) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2006.05.001 · Cited by 75 · see citing works
Self-citationHeidbüchel, H., & Gerche, A. L. (2012) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-012-0180-3 · Cited by 74 · see citing works
Does sports activity enhance the risk of sudden cardiac death?
Corrado, D., Basso, C., Schiavon, M., & Thiene, G. (2006) · Journal of Cardiovascular Medicine · doi:10.2459/01.jcm.0000219313.89633.45 · Cited by 73 · see citing works
Regional wall motion abnormalities after prolonged exercise in the normal left ventricle.
Douglas, P. S., OʼToole, M. L., & Woolard, J. (1990) · Circulation · doi:10.1161/01.cir.82.6.2108 · Cited by 73 · see citing works
Self-citationShort-term effects of marathon running: no evidence of cardiac dysfunction
A, A. L., Serratosa, L., Saborido, A., Pardo, J., Boraíta, A., N, M. A. M., S, F. B., AS, A. M., & Chicharro, J. L. (1999) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199910000-00009 · Cited by 71 · see citing works
Right Ventricular Myocardial Adaptation to Different Training Protocols in Top‐Level Athletes
D’Andrea, A., Caso, P., Sarubbi, B., Limongelli, G., Liccardo, B., Cice, G., D’Andrea, L., Scherillo, M., Cotrufo, M. F., & Calabrò, R. (2003) · Echocardiography · doi:10.1046/j.1540-8175.2003.03038.x · Cited by 69 · see citing works
Biventricular myocardial adaptation to different training protocols in competitive master athletes
D’Andrea, A., Caso, P., Scarafile, R., Salerno, G., Corato, G. D., Mita, C., Salvo, G. D., Allocca, F., Colonna, D., Caprile, M., et al. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.03.041 · Cited by 67 · see citing works
The impact of repeated marathon running on cardiovascular function in the aging population
Karlstedt, E., Chelvanathan, A., Silva, M. D., Cleverley, K., Kumar, K., Bhullar, N., Lytwyn, M., Bohonis, S., Oomah, S., Nepomuceno, R. G., et al. (2012) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-14-58 · Cited by 63 · see citing works
Clinical Significance of Cardiac Damage and Changes in Function after Exercise
Whyte, G. P. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318172cefd · Cited by 63 · see citing works
D’Andrea, A., D’Andrea, L., Caso, P., Scherillo, M., Zeppilli, P., & Calabrò, R. (2006) · Echocardiography · doi:10.1111/j.1540-8175.2006.00186.x · Cited by 60 · see citing works
The Impact of Triathlon Training and Racing on Athletes’ General Health
Vleck, V. E., Millet, G. P., & Alves, F. B. (2014) · Sports Medicine · doi:10.1007/s40279-014-0244-0 · Cited by 59 · see citing works
Gerche, A. L., Roberts, T., & Claessen, G. (2014) · Pulmonary Circulation · doi:10.1086/677355 · Cited by 58 · see citing works
D’Andrea, A., Caso, P., Galderisi, M., Maggio, D. D., Cicala, S., D’Andrea, L., Mininni, N., & Calabrò, R. (2001) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)01505-3 · Cited by 56 · see citing works
Right Heart Structural and Functional Remodeling in Athletes
D’Andrea, A., Gerche, A. L., Golia, E., Teske, A. J., Bossone, E., Russo, M. G., Calabrò, R., & Baggish, A. L. (2014) · Echocardiography · doi:10.1111/echo.12226 · Cited by 54 · see citing works
Banks, L., Sasson, Z., Busato, M., & Goodman, J. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00898.2009 · Cited by 53 · see citing works
Oxborough, D., Shave, R., Middleton, N., Whyte, G. P., Forster, J., & George, K. (2006) · Echocardiography · doi:10.1111/j.1540-8175.2006.00282.x · Cited by 53 · see citing works
Poh, K. K., Ton-Nu, T.-T., Neilan, T. G., Tournoux, F., Picard, M. H., & Wood, M. J. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2007.04.051 · Cited by 50 · see citing works
Donaldson, J. A., Wiles, J. D., Coleman, D. A., Papadakis, M., Sharma, R., & O’Driscoll, J. M. (2019) · Sports Medicine · doi:10.1007/s40279-019-01142-5 · Cited by 48 · see citing works
Henriksen, E. (1999) · European Heart Journal · doi:10.1053/euhj.1998.1197 · Cited by 48 · see citing works
D’Andrea, A., Caso, P., Severino, S., Sarubbi, B., Forni, A., Cice, G., Esposito, N., Scherillo, M., Cotrufo, M. F., & Calabrò, R. (2003) · Journal of the American Society of Echocardiography · doi:10.1067/mje.2003.29 · Cited by 47 · see citing works
The effects of prolonged strenuous exercise on left ventricular function: A brief review
McGavock, J., Warburton, D. E. R., Taylor, D. A., Welsh, R. C., Quinney, H. A., & Haykowsky, M. J. (2002) · Heart & Lung · doi:10.1067/mhl.2002.126106 · Cited by 46 · see citing works
Exercise as Cardiovascular Therapy
Koller, A. (2000) · Circulation · doi:10.1161/01.cir.101.14.e164 · Cited by 47 · see citing works
Impact of ethnicity on cardiac adaptation to exercise
Sheikh, N., & Sharma, S. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2014.15 · Cited by 44 · see citing works
Postexercise Changes in Left Ventricular Function
Shave, R., George, K., Whyte, G. P., Hart, E. C., & Middleton, N. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318172cf36 · Cited by 45 · see citing works
Left ventricular performance during prolonged exercise: absence of systolic dysfunction
Goodman, J. M., McLaughlin, P. R., & Liu, P. P. (2001) · Clinical Science · doi:10.1042/cs1000529 · Cited by 45 · see citing works
Ashley, E. A., Kardos, A., Jack, E. S., Habenbacher, W., Wheeler, M. T., Kim, Y. M., Froning, J. N., MYERS, J. N., Whyte, G. P., Froelicher, V. F., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.02.071 · Cited by 44 · see citing works
Self-citationLeft Ventricular Hypertrophy in Athletes: Morphologic Features and Clinical Correlates
Atchley, A. E., & Douglas, P. S. (2007) · Cardiology Clinics · doi:10.1016/j.ccl.2007.06.009 · Cited by 42 · see citing works
Self-citationAcute and Chronic Response to Exercise in Athletes: The “Supernormal Heart”
D’Andrea, A., Formisano, T., Riegler, L., Scarafile, R., America, R., Martone, F., Maio, M. D., Russo, M. G., Bossone, E., Galderisi, M., et al. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-4307-9_2 · Cited by 39 · see citing works
Foury, F., Hu, J., & Vanderstraeten, S. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4220-y · Cited by 37 · see citing works
Esposito, R., Galderisi, M., Schiano-Lomoriello, V., Santoro, A., Palma, D. D., Ippolito, R., Muscariello, R., Santoro, C., Guerra, G., Cameli, M., et al. (2013) · Echocardiography · doi:10.1111/echo.12499 · Cited by 36 · see citing works
Niessner, A., Ziegler, S., Slany, J., Billensteiner, E., Woloszczuk, W., & Geyer, G. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1490555 · Cited by 36 · see citing works
The role of new echocardiographic techniques in athlete’s heart
D’Andrea, A., Bossone, E., Radmilovic, J., Caso, P., Calabrò, R., Russo, M. G., & Galderisi, M. (2015) · F1000Research · doi:10.12688/f1000research.6745.1 · Cited by 35 · see citing works
Right ventricular myocardial performance index and exercise capacity in athletes
Kaşıkçıoğlu, E., Oflaz, H., Akhan, H., & Kayserilioğlu, A. (2005) · Heart and Vessels · doi:10.1007/s00380-005-0824-x · Cited by 35 · see citing works
Tümüklü, M. M., Etikán, Í., & Çınar, C. S. (2007) · International journal of cardiac imaging · doi:10.1007/s10554-007-9218-8 · Cited by 34 · see citing works
Genetics of sudden cardiac death in children and young athletes
Sarquella-Brugada, G., Campuzano, Ó., Iglesias, A., Sánchez-Malagón, J., Guerra-Balic, M., Brugada, J., & Brugada, R. (2012) · Cardiology in the Young · doi:10.1017/s1047951112001138 · Cited by 35 · see citing works
Leischik, R., Dworrak, B., Strauss, M., Horlitz, M., Pareja-Galeano, H., de la Guía-Galipienso, F., Lippi, G., Lavie, C. J., Perez, M. V., & Sanchis‐Gomar, F. (2020) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2020.03.015 · Cited by 34 · see citing works
Grünig, E., Biskupek, J., D’Andrea, A., Ehlken, N., Egenlauf, B., Weidenhammer, J., Marra, A. M., Cittadini, A., Fischer, C., & Bossone, E. (2015) · Respiration · doi:10.1159/000371472 · Cited by 32 · see citing works
Caso, P., Galderisi, M., D’Andrea, A., Maggio, D. D., Simone, L. D., Martiniello, A. R., Mininni, N., Calabrò, R., & Sutherland, G. R. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02453-0 · Cited by 31 · see citing works
Chan-Dewar, F., Oxborough, D., Shave, R., Gregson, W. A., Whyte, G., Noakes, T. D., & George, K. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-009-1264-6 · Cited by 30 · see citing works
The Impact of Ethnicity on Cardiac Adaptation
Ozo, U., & Sharma, S. (2020) · European Cardiology Review · doi:10.15420/ecr.2020.01 · Cited by 28 · see citing works
Lord, R. N., Somauroo, J. D., Stembridge, M. R., Jain, N., Hoffman, M. D., George, K., Jones, H., Shave, R., Haddad, F., Ashley, E. A., et al. (2014) · European Journal of Applied Physiology · doi:10.1007/s00421-014-2995-6 · Cited by 28 · see citing works
Pulmonary Circulation at Exercise
Naeije, R., & Chesler, N. C. (2012) · Comprehensive physiology · doi:10.1002/j.2040-4603.2012.tb00405.x · Cited by 27 · see citing works
Basso, C., Corrado, D., & Thiene, G. (2007) · Cardiology Clinics · doi:10.1016/j.ccl.2007.08.009 · Cited by 27 · see citing works
Goff, Z. D., & Calkins, H. G. (2019) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2019.04.002 · Cited by 25 · see citing works
Cardiac adaptation to acute and chronic participation in endurance sports
George, K., Spence, A. L., Naylor, L. H., Whyte, G., & GREEN, D. J. (2011) · Heart · doi:10.1136/heartjnl-2011-300536 · Cited by 24 · see citing works
The Mystery of Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
Marcus, G. M., & Towbin, J. A. (2006) · Circulation · doi:10.1161/circulationaha.106.653493 · Cited by 24 · see citing works
The arrhythmogenic right ventricular cardiomyopathy in comparison to the athletic heart
Mascia, G., Arbelo, E., Porto, I., Brugada, R., & Brugada, J. (2020) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14526 · Cited by 23 · see citing works
Ljones, K., Ness, H. O., Solvang‐Garten, K., Gaustad, S. E., & Høydal, M. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0173449 · Cited by 23 · see citing works
Physiologic and pathophysiologic changes in the right heart in highly trained athletes
D’Andrea, A., Gerche, A. L., Golia, E., Padalino, R., Calabrò, R., Russo, M. G., & Bossone, E. (2015) · Herz · doi:10.1007/s00059-015-4220-8 · Cited by 21 · see citing works
Displasia arritmogénica del ventrículo derecho
Brugada, J., Mont, L., & Brugada, R. (1997) · Revista Española de Cardiología · doi:10.1016/s0300-8932(97)73261-5 · Cited by 21 · see citing works
George, K., Shave, R., Warburton, D. E. R., Scharhag, J., & Whyte, G. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318172ceec · Cited by 19 · see citing works
Loomba, R. S., Danduran, M., Dixon, J. E., & Rao, R. P. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0817-y · Cited by 19 · see citing works
Sudden Death in Young Athletes
Corrado, D., Basso, C., & Thiene, G. (2007) · Springer eBooks · doi:10.1007/978-88-470-0490-0_23 · Cited by 19 · see citing works
Rojas, A., & Calkins, H. G. (2014) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2014.10.007 · Cited by 18 · see citing works
Comparison of left and right ventricular adaptation in endurance-trained male athletes
Major, Z., Csajági, E., Kneffel, Z., Kováts, T., Szauder, I., Sidó, Z., & Pavlik, G. (2015) · Acta Physiologica Hungarica · doi:10.1556/aphysiol.102.2015.1.2 · Cited by 18 · see citing works
D’Andrea, A., Galderisi, M., Sciomer, S., Nistri, S., Agricola, E., Ballo, P., Buralli, S., D’Errico, A., Losi, M. A., Mele, D., et al. (2009) · PubMed · Cited by 17 · see citing works
Mills, J. D., Moore, G. E., & Thompson, P. D. (1997) · Clinics in Sports Medicine · doi:10.1016/s0278-5919(05)70050-8 · Cited by 17 · see citing works
- Authors
- Douglas, P. S., O'Toole, M. L., Miller, W. D. B., & Reichek, N.
- Affiliations
- Hospital of the University of Pennsylvania (US)
- Baptist Memorial Hospital (US)
- Corresponding author
- Douglas, Pamela S.
- ORCID
- Douglas, Pamela S.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1990-01
- Volume
- 15
- Issue
- 1
- Pages
- 64-69
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2077549315
- Cited by
- 172
- References
- 25
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 4 · 2017: 10 · 2016: 3 · 2015: 12 · 2014: 13 · 2013: 7 · 2012: 9
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- prolonged exercise, right ventricle, left ventricle, right ventricular hypertrophy, athletes, triathlon, cardiac chamber dimensions, mitral regurgitation, tricuspid regurgitation, post-exercise recovery, right ventricular compliance, echocardiography
- MeSH terms
- Adult, Bicycling, Coronary Circulation, Echocardiography, Physical Exertion, Female, Humans, Male, Myocardial Contraction, Physical Endurance, Running, Stroke Volume, Swimming, Echocardiography, Doppler, Ventricular Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
