Cited by 129Parkinson's Disease Mechanisms and TreatmentsHeart Rate Variability and Autonomic ControlCardiovascular Syncope and Autonomic Disorders

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Central control of autonomic function and involvement in neurodegenerative disorders

Maria Graciela Cersosimo, Eduardo Elias Benarroch·2013·Handbook of Clinical Neurology

DOI 10.1016/b978-0-444-53491-0.00005-5

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Abstract

The central autonomic network includes the insular cortex, anterior cingulate cortex, amygdala, hypothalamus, periaqueductal gray, parabrachial nucleus, nucleus of the solitary tract, ventrolateral reticular formation of the medulla, and medullary raphe. These areas: are reciprocally interconnected; receive converging visceral and somatosensory information; generate stimulus-specific patterns of autonomic, endocrine, and motor responses; and are regulated according to the behavioral state, including the sleep-wake cycle. Several components of the central autonomic networks are affected in neurodegenerative disorders characterized by the presence of intracellular inclusions containing α-synuclein. These include multiple system atrophy (MSA), characterized by accumulation of glial cytoplasmic inclusions, and Lewy body disorders, including Parkinson disease (PD), dementia with Lewy bodies, and the so-called "pure" autonomic failure. In MSA, involvement of the rostral ventrolateral medulla may be primarily responsible for orthostatic hypotension; involvement in the pontine micturition area, sacral preganglionic nucleus, and Onuf nucleus is responsible for neurogenic bladder; and involvement of the pre-Bötzinger complex and medullary raphe may contribute to sleep-related respiratory abnormalities. In contrast, Lewy body disorders are characterized by early involvement of the enteric nervous system and cardiac sympathetic ganglia. The dorsal motor nucleus of the vagus is affected b…

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Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H., Cummings, J., Duda, J. E., Lippa, C., Perry, E. K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187889.17253.b1 · Cited by 5,069
Neural regulation of endocrine and autonomic stress responses
Ulrich-Lai, Y. M., & Herman, J. P. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2647 · Cited by 3,318
Second consensus statement on the diagnosis of multiple system atrophy
Gilman, S., Wenning, G. K., Low, P. A., Brooks, D. J., Mathias, C. J., Trojanowski, J. Q., Wood, N. W., Colosimo, C., Dürr, A., Fowler, C. J., et al. (2008) · Neurology · doi:10.1212/01.wnl.0000324625.00404.15 · Cited by 3,140
Interoception: the sense of the physiological condition of the body
(Bud) Craig, A. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00090-4 · Cited by 2,556
The role of the amygdala in fear and anxiety
Davis, M. (1992) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.15.030192.002033 · Cited by 2,357
The sympathetic control of blood pressure
Guyenet, P. G. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1902 · Cited by 1,863
Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
Braak, H., R�b, U., Gai, W. P., & Del Tredici, K. (2003) · Journal of Neural Transmission · doi:10.1007/s00702-002-0808-2 · Cited by 1,683
The neural control of micturition
Fowler, C. J., GRIFFITHS, D. J., & de Groat, W. C. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2401 · Cited by 1,492
The amygdala
LeDoux, J. (2007) · Current Biology · doi:10.1016/j.cub.2007.08.005 · Cited by 1,281
Neural mechanisms of autonomic, affective, and cognitive integration
Critchley, H. D. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20749 · Cited by 1,214
Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence
Critchley, H. D., Mathias, C. J., Josephs, O., O’Doherty, J., Zanini, S., Dewar, B., Cipolotti, L., Shallice, T., & Dolan, R. J. (2003) · Brain · doi:10.1093/brain/awg216 · Cited by 1,201
Descending control of nociception: Specificity, recruitment and plasticity
Heinricher, M. M., Tavares, I., Leith, J. L., & Lumb, B. M. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.12.009 · Cited by 953
B REATHING : Rhythmicity, Plasticity, Chemosensitivity
Feldman, J. L., Mitchell, G. S., & Nattie, E. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131103 · Cited by 851
The central autonomic nervous system: conscious visceral perception and autonomic pattern generation
Saper, C. B. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.032502.111311 · Cited by 837
Efferent projections of the infralimbic cortex of the rat
Hurley, K. M., Herbert, H., Moga, M. M., & Saper, C. B. (1991) · Journal of Comparative Neurology · doi:10.1002/cne.903080210 · Cited by 777
Mapping the functional connectivity of anterior cingulate cortex
Margulies, D. S., Kelly, C. A. M., Uddin, L. Q., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.05.019 · Cited by 777
Three systems of insular functional connectivity identified with cluster analysis
Deen, B., Pitskel, N. B., & Pelphrey, K. A. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq186 · Cited by 716
Stanley Fahn Lecture 2005: the staging procedure for the inclusion body pathology associated with sporadic Parkinson’s disease reconsidered
Braak, H., Bohl, J. R., Müller, C. M., Rüb, U., de Vos, R. A. I., & Del Tredici, K. (2006) · Movement Disorders · doi:10.1002/mds.21065 · Cited by 630
Forebrain emotional asymmetry: a neuroanatomical basis?
Craig, A. D. (. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.10.005 · Cited by 626
A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections
Strack, A. M., Sawyer, W. B., Hughes, J., Platt, K. B., & Loewy, A. D. (1989) · Brain Research · doi:10.1016/0006-8993(89)90098-x · Cited by 591
Central circuits mediating patterned autonomic activity during active vs. passive emotional coping
Bandler, R., Keay, K. A., Floyd, N., & Price, J. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00313-0 · Cited by 582
A PET study on brain control of micturition in humans
Blok, B. F. M. (1997) · Brain · doi:10.1093/brain/120.1.111 · Cited by 507
Brainstem circuits regulating gastric function
Travagli, R. A., Hermann, G. E., Browning, K. N., & Rogers, R. C. (2006) · Annual Review of Physiology · doi:10.1146/annurev.physiol.68.040504.094635 · Cited by 498
Identification of Wake-Active Dopaminergic Neurons in the Ventral Periaqueductal Gray Matter
Lu, J., Jhou, T. C., & Saper, C. B. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2244-05.2006 · Cited by 475
Central control of thermogenesis in mammals
Morrison, S. F., Nakamura, K., & Madden, C. J. (2008) · Experimental Physiology · doi:10.1113/expphysiol.2007.041848 · Cited by 424
Neuropathology of Autonomic Nervous System in Parkinson's Disease
Wakabayashi, K., & Takahashi, H. (2008) · European Neurology · doi:10.1159/000113469 · Cited by 407
Integrative control of the lower urinary tract: preclinical perspective
de Groat, W. C. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706604 · Cited by 406
Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease
Halliday, G. M., Blumbergs, P. C., Cotton, R. G. H., Blessing, W. W., & Geffen, L. B. (1990) · Brain Research · doi:10.1016/0006-8993(90)90733-r · Cited by 379
Circuits and mechanisms governing hypothalamic responses to stress: a tale of two paradigms
Sawchenko, P. E., Li, H.-Y., & Ericsson, A. B. (2000) · Progress in brain research · doi:10.1016/s0079-6123(08)62131-7 · Cited by 353
Cortical Modulation of theCardiovascular System
Verberne, A. J. M., & Owens, N. C. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00056-7 · Cited by 351
Multiple system atrophy: A primary oligodendrogliopathy
Wenning, G. K., Stefanova, N., Jellinger, K. A., Poewe, W. H., & Schlossmacher, M. G. (2008) · Annals of Neurology · doi:10.1002/ana.21465 · Cited by 329
The insular cortex and cardiovascular system: a new insight into the brain-heart axis
Nagai, M., Hoshide, S., & Kario, K. (2010) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2010.05.001 · Cited by 328
Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants
Critchley, H. D. (2009) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2009.01.012 · Cited by 323
Sympathetic Cardioneuropathy in Dysautonomias
Goldstein, D. S., Holmes, C. S., Cannon, R. O., Eisenhofer, G., & Kopin, I. J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199703063361004 · Cited by 322
The dorsomedial hypothalamus: a new player in thermoregulation
DiMicco, J. A., & Zaretsky, D. V. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00498.2006 · Cited by 300
Structural and functional architecture of respiratory networks in the mammalian brainstem
Smith, J. C., Abdala, A. P., Rybak, I. A., & Paton, J. F. R. (2009) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0081 · Cited by 284
Enteric nervous system
Grundy, D., & Schemann, M. (2007) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e3280287a23 · Cited by 283
Paraventricular hypothalamic nucleus: Axonal projections to the brainstem
Geerling, J. C., Shin, J., Chimenti, P. C., & Loewy, A. D. (2010) · Journal of Comparative Neurology · doi:10.1002/cne.22283 · Cited by 273
Are synucleinopathies prion-like disorders?
Angot, E., Steiner, J. A., Hansen, C., Li, J.-Y., & Brundin, P. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70213-1 · Cited by 251
Central respiratory chemoreception
Guyenet, P. G., Stornetta, R. L., & Bayliss, D. A. (2010) · The Journal of Comparative Neurology · doi:10.1002/cne.22435 · Cited by 249
The location of cardiac vagal preganglionic motoneurones in the medulla of the cat.
McAllen, R. M., & Spyer, K. M. (1976) · The Journal of Physiology · doi:10.1113/jphysiol.1976.sp011414 · Cited by 248
Neural structures that mediate sympathoexcitation during hypoxia
Guyenet, P. G. (2000) · Respiration Physiology · doi:10.1016/s0034-5687(00)00125-0 · Cited by 246
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α‐synuclein staging
Kalaitzakis, M. E., Graeber, M. B., Gentleman, S., & Pearce, R. K. B. (2007) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2007.00923.x · Cited by 243
Degeneration of Cardiac Sympathetic Nerve Begins in the Early Disease Process of Parkinson’s Disease
Orimo, S., Takahashi, A., Uchihara, T., Mori, F., Kakita, A., Wakabayashi, K., & Takahashi, H. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2006.00032.x · Cited by 243
A critical reappraisal of current staging of Lewy-related pathology in human brain
Jellinger, K. A. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0406-y · Cited by 240
Cortical regions associated with autonomic cardiovascular regulation during lower body negative pressure in humans
Kimmerly, D. S., O’Leary, D. D., Menon, R. S., Gati, J. S., & Shoemaker, J. K. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.091637 · Cited by 236
Central chemoreception is a complex system function that involves multiple brain stem sites
Nattie, E., & Li, A. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00112.2008 · Cited by 223
Architecture and neurocytology of monkey cingulate gyrus
Vogt, B. A., Vogt, L., Farber, N. B., & Bush, G. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20512 · Cited by 223
A decade of functional brain imaging applied to bladder control
Fowler, C. J., & GRIFFITHS, D. J. (2009) · Neurourology and Urodynamics · doi:10.1002/nau.20740 · Cited by 222
The pontine REM switch: past and present
Fuller, P. M., Saper, C. B., & Lu, J. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.140160 · Cited by 221
Structural characterization of a hypothalamic visceromotor pattern generator network
Thompson, R. H. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00232-1 · Cited by 204
RVLM and raphe differentially regulate sympathetic outflows to splanchnic and brown adipose tissue
Morrison, S. F. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.276.4.r962 · Cited by 200
Bladder dysfunction in Parkinsonism: Mechanisms, prevalence, symptoms, and management
Winge, K., & Fowler, C. J. (2006) · Movement Disorders · doi:10.1002/mds.20867 · Cited by 200
Human forebrain activation by visceral stimuli
King, A. B., Menon, R. S., Hachinski, V., & Cechetto, D. F. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19991101)413:4 · Cited by 200
Central representation of visceral function.
Cechetto, D. F. (1987) · PubMed · Cited by 198
Sleep disorders in multiple system atrophy: a correlative video-polysomnographic study
Vetrugno, R., Provini, F., Cortelli, P., Plazzi, G., Lotti, E. M., Pierangeli, G., Canali, C., & Montagna, P. (2003) · Sleep Medicine · doi:10.1016/j.sleep.2003.07.002 · Cited by 191
Central representation of the sympathetic nervous system in the cerebral cortex
Westerhaus, M. J., & Loewy, A. D. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02453-2 · Cited by 189
Neural control of the gastrointestinal tract: Implications for Parkinson disease
Cersosimo, M. G., & Benarroch, E. E. (2008) · Movement Disorders · doi:10.1002/mds.22051 · Cited by 188
Self-citation
The rat medial frontal cortex projects directly to autonomic regions of the brainstem
Terreberry, R. R., & Neafsey, E. J. (1987) · Brain Research Bulletin · doi:10.1016/0361-9230(87)90050-5 · Cited by 177
Neural control of the lower urinary tract: Peripheral and spinal mechanisms
Birder, L. A., de Groat, W., Mills, I. W., Morrison, J., Thor, K. B., & Drake, M. J. (2009) · Neurourology and Urodynamics · doi:10.1002/nau.20837 · Cited by 174
IV. Current concepts of vagal efferent projections to the gut
Chang, H. Y., Mashimo, H. L., & Goyal, R. K. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00478.2002 · Cited by 172
Paraventricular nucleus, stress response, and cardiovascular disease
Benarroch, E. E. (2005) · Clinical Autonomic Research · doi:10.1007/s10286-005-0290-7 · Cited by 170
Self-citation
Functional Organization of Brain Pathways Subserving the Baroreceptor Reflex: Studies in Conscious Animals Using Immediate Early Gene Expression
Dampney, R. A. L., Polson, J. W., Potts, P. D., Hirooka, Y., & Horiuchi, J. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1025080314925 · Cited by 170
The Midbrain Periaqueductal Gray Control of Respiration
Subramanian, H. H., Balnave, R. J., & Holstege, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4168-08.2008 · Cited by 162
Parallel preoptic pathways for thermoregulation
Yoshida, K., Li, X., Cano, G., Lazarus, M., & Saper, C. B. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2643-09.2009 · Cited by 160
Functional organisation of central cardiovascular pathways: studies using c-fos gene expression
Dampney, R. A. L., & Horiuchi, J. (2003) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2003.11.001 · Cited by 157
Medullary serotonin neurons and central CO2 chemoreception
Corcoran, A. E., Hodges, M. R., Wu, Y., Wang, W., Wylie, C. J., Deneris, E. S., & Richerson, G. B. (2009) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2009.04.014 · Cited by 155
Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model
Kingsbury, A. E., Bandopadhyay, R., Silveira‐Moriyama, L., Ayling, H., Kallis, C., Sterlacci, W., Maeir, H., Poewe, W. H., & Lees, A. J. (2010) · Movement Disorders · doi:10.1002/mds.23305 · Cited by 152
Dissecting axes of autonomic control in humans: insights from neuroimaging
Critchley, H. D., Nagai, Y., Gray, M. A., & Mathias, C. J. (2011) · Autonomic Neuroscience · doi:10.1016/j.autneu.2010.09.005 · Cited by 152
Neuroanatomy of cardiac activity-regulating circuitry: a transneuronal retrograde viral labelling study in the rat
Ter Horst, G. J., Hautvast, R. W. M., De Jongste, M. J. L., & Korf, J. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb00723.x · Cited by 149
Involvement of vagal autonomic nuclei in multiple system atrophy and Lewy body disease
Benarroch, E. E., Schmeichel, A. M., Sandroni, P., Low, P. A., & Parisi, J. E. (2006) · Neurology · doi:10.1212/01.wnl.0000196638.98781.bb · Cited by 146
Self-citation
Vagal control of the heart: central serotonergic (5‐HT) mechanisms
Jordan, D. (2004) · Experimental Physiology · doi:10.1113/expphysiol.2004.029058 · Cited by 145
Micturition and the soul
Holstege, G. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20785 · Cited by 143
Neurocirculatory Abnormalities in Parkinson Disease With Orthostatic Hypotension
Goldstein, D. S., Eldadah, B. A., Holmes, C. S., Pechnik, S., Moak, J. P., Saleem, A., & Sharabi, Y. (2005) · Hypertension · doi:10.1161/01.hyp.0000188052.69549.e4 · Cited by 140
Depletion of catecholaminergic neurons of the rostral ventrolateral medulla in multiple systems atrophy with autonomic failure
Benarroch, E. E., Smithson, I. L., Low, P. A., & Parisi, J. E. (1998) · Annals of Neurology · doi:10.1002/ana.410430205 · Cited by 133
Self-citation
Le noyau du faisceau solitaire : Aspects neuroanatomiques, neurochimiques et fonctionnels
Jean, A. (1991) · Archives of Physiology and Biochemistry · doi:10.3109/13813459109145916 · Cited by 132
Parkinson’s disease and the gut: a well known clinical association in need of an effective cure and explanation
Natale, G., Pasquali, L., Ruggieri, S. A., Paparelli, A., & Fornai, F. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01162.x · Cited by 131
Neurophysiological analysis of target‐related sympathetic pathways – from animal to human: similarities and differences*
Jänig, W., & Häbler, H. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01088.x · Cited by 131
Autonomic Failure in Neurodegenerative Disorders
Kaufmann, H., & Biaggioni, I. (2003) · Seminars in Neurology · doi:10.1055/s-2004-817719 · Cited by 129
Degeneration of cardiac sympathetic nerve can occur in multiple system atrophy
Orimo, S., Kanazawa, T., Nakamura, A., Uchihara, T., Mori, F., Kakita, A., Wakabayashi, K., & Takahashi, H. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0160-y · Cited by 124
Lateral horn cells in progressive autonomic failure
Oppenheimer, D. R. (1980) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(80)90064-7 · Cited by 122
Cortical, thalamic, and hypothalamic responses to cooling and warming the skin in awake humans: A positron-emission tomography study
Egan, G. F., Johnson, J. M., Farrell, M. J., McAllen, R. M., Zamarripa, F., McKinley, M. J., Lancaster, J. L., Denton, D. A., & Fox, P. T. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409753102 · Cited by 118
Hypothalamic mechanisms coordinating cardiorespiratory function during exercise and defensive behaviour
Dampney, R. A. L., Horiuchi, J., & McDowall, L. M. (2008) · Autonomic Neuroscience · doi:10.1016/j.autneu.2008.07.005 · Cited by 116
Depletion of medullary serotonergic neurons in patients with multiple system atrophy who succumbed to sudden death
Tada, M., Kakita, A., Toyoshima, Y., Onodera, O., Ozawa, T., Morita, T., Nishizawa, M., & Takahashi, H. (2009) · Brain · doi:10.1093/brain/awp110 · Cited by 115
The sympathetic nervous system in hypertension
Diedrich, A., Jordan, J., Tank, J., Shannon, J. R., Robertson, R. M., Luft, F. C., Robertson, D., & Biaggioni, I. (2003) · Journal of Hypertension · doi:10.1097/00004872-200309000-00017 · Cited by 113
Ascending noradrenergic projections from the brainstem: Evidence for a major role in the regulation of blood pressure and vasopressin secretion
Lightman, S. L., Todd, K., & Everitt, B. J. (1984) · Experimental Brain Research · doi:10.1007/bf00240508 · Cited by 110
Functional organization of the parabrachial complex and intertrigeminal region in the control of breathing
Chamberlin, N. L. (2004) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2004.03.015 · Cited by 109
Involvement of medullary serotonergic groups in multiple system atrophy
Benarroch, E. E., Schmeichel, A. M., Low, P. A., & Parisi, J. E. (2004) · Annals of Neurology · doi:10.1002/ana.20021 · Cited by 107
Self-citation
Depletion of putative chemosensitive respiratory neurons in the ventral medullary surface in multiple system atrophy
Benarroch, E. E., Schmeichel, A. M., Low, P. A., & Parisi, J. E. (2007) · Brain · doi:10.1093/brain/awl357 · Cited by 106
Self-citation
Dorsal motor nucleus of the vagus nerve: A cyto‐ and chemoarchitectonic study in the human
Huang, X., Törk, I., & Paxinos, G. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903300203 · Cited by 95
Candidate cell populations for respiratory chemosensitive fields in the human infant medulla
Filiano, J. J., Choi, J. C., & Kinney, H. C. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902930308 · Cited by 95
Functional Anatomy of Sympathetic Premotor Cell Groups in the Medulla
McAllen, R. M., May, C. N., & Shafton, A. D. (1995) · Clinical and Experimental Hypertension · doi:10.3109/10641969509087066 · Cited by 93
Real‐time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake subjects
Macefield, V. G., & Henderson, L. A. (2009) · Human Brain Mapping · doi:10.1002/hbm.20885 · Cited by 92
Cortical and brain stem changes in neural activity during static handgrip and postexercise ischemia in humans
Sander, M., Macefield, V. G., & Henderson, L. A. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91539.2008 · Cited by 87
Involvement of medullary regions controlling sympathetic output in Lewy body disease
Benarroch, E. E. (2004) · Brain · doi:10.1093/brain/awh376 · Cited by 85
Self-citation
Sleep disorders in multiple system atrophy
Ghorayeb, I., Bioulac, B. H., & Tison, F. (2005) · Journal of Neural Transmission · doi:10.1007/s00702-005-0348-7 · Cited by 81
Morphological substrate of autonomic failure and neurohormonal dysfunction in multiple system atrophy: impact on determining phenotype spectrum
Ozawa, T. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0254-1 · Cited by 79
Involvement of the ventrolateral medulla in parkinsonism with autonomic failure
Benarroch, E. E., AS, A. M. S., & Parisi, J. E. (2000) · Neurology · doi:10.1212/wnl.54.4.963 · Cited by 79
Self-citation
Human medullary responses to cooling and rewarming the skin: A functional MRI study
McAllen, R. M., Farrell, M. J., Johnson, J. M., Trevaks, D., Cole, L. J., McKinley, M. J., Jackson, G. D., Denton, D. A., & Egan, G. F. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509862103 · Cited by 78
A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome.
Kennedy, P. G. E., & Duchen, L. W. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.11.1103 · Cited by 75
Generalized and neurotransmitter‐selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension
Sharabi, Y., Imrich, R., Holmes, C. S., Pechnik, S., & Goldstein, D. S. (2008) · Movement Disorders · doi:10.1002/mds.22226 · Cited by 74
Cardiovascular and thermal responses evoked from the periaqueductal grey require neuronal activity in the hypothalamus
de Menezes, R. C. A., Zaretsky, D. V., Fontes, M. A. P., & DiMicco, J. A. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.161463 · Cited by 72
Cardiac denervation in patients with Parkinson disease.
Goldstein, D. S. (2007) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.74.suppl_1.s91 · Cited by 72
Lewy bodies in the lower sacral parasympathetic neurons of a patient with Parkinson's disease
Oyanagi, K., Wakabayashi, K., Ohama, E., Takeda, S., Horikawa, Y., Morita, T., & Ikuta, F. (1990) · Acta Neuropathologica · doi:10.1007/bf00294619 · Cited by 68
Clinical and physiological characteristics of autonomic failure with Parkinson's disease
Niimi, Y., Ieda, T., Hirayama, M., Koike, Y., Sobue, G., Hasegawa, Y., & Takahashi, A. (1999) · Clinical Autonomic Research · doi:10.1007/bf02281627 · Cited by 66
Neurochemistry of bulbospinal presympathetic neurons of the medulla oblongata
Stornetta, R. L. (2009) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2009.07.005 · Cited by 62
Iodine-123-MIBG sympathetic imaging in Lewy-body diseases and related movement disorders.
Nakajima, K., Yoshita, M., Matsuo, S., Taki, J., & Kinuya, S. (2008) · PubMed · Cited by 61
Serotonergic and glutamatergic neurons at the ventral medullary surface of the human infant: Observations relevant to central chemosensitivity in early human life
Paterson, D. S., Thompson, E. G., & Kinney, H. C. (2006) · Autonomic Neuroscience · doi:10.1016/j.autneu.2005.12.009 · Cited by 59
Descending Pathways to the Sympathetic Preganglionic Neurons
Loewy, A. D. (1982) · Progress in brain research · doi:10.1016/s0079-6123(08)64133-3 · Cited by 57
New findings on the neuropathology of multiple system atrophy
Benarroch, E. E. (2002) · Autonomic Neuroscience · doi:10.1016/s1566-0702(01)00374-5 · Cited by 56
Self-citation
Sphincter EMG as a diagnostic tool in autonomic disorders
Sakakibara, R., Uchiyama, T., Yamanishi, T., & Kishi, M. (2008) · Clinical Autonomic Research · doi:10.1007/s10286-008-0489-5 · Cited by 55
Morphometric study of nucleus ambiguus in multiple system atrophy presenting with vocal cord abductor paralysis.
Isozaki, E., Matsubara, S., Hayashida, T., Oda, M., & Hirai, S. (2000) · PubMed · Cited by 52
Differential involvement of hypothalamic vasopressin neurons in multiple system atrophy
Benarroch, E. E. (2006) · Brain · doi:10.1093/brain/awl109 · Cited by 51
Self-citation
Suprachiasmatic nucleus in a patient with multiple system atrophy with abnormal circadian rhythm of arginine-vasopressin secretion into plasma
Ozawa, T., Oyanagi, K., Tanaka, H., Horikawa, Y., Takahashi, H., Morita, T., & Tsuji, S. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(97)00210-4 · Cited by 49
Dopamine cell loss in the periaqueductal gray in multiple system atrophy and Lewy body dementia
Benarroch, E. E., Schmeichel, A. M., Dugger, B. N., Sandroni, P., Parisi, J. E., & Low, P. A. (2009) · Neurology · doi:10.1212/wnl.0b013e3181ad53e7 · Cited by 48
Self-citation
Preservation of branchimotor neurons of the nucleus ambiguus in multiple system atrophy
Benarroch, E. E., Schmeichel, A. M., & Parisi, J. E. (2003) · Neurology · doi:10.1212/01.wnl.0000042087.07133.87 · Cited by 46
Self-citation
Maps of cardiovascular and respiratory regions of rat ventral medulla: Focus on the caudal medulla
Goodchild, A. K., & Moon, E. A. (2009) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2009.06.002 · Cited by 43
Respiratory responses elicited by rostral versus caudal dorsal periaqueductal gray stimulation in rats
Zhang, W., Hayward, L. F., & Davenport, P. W. (2007) · Autonomic Neuroscience · doi:10.1016/j.autneu.2007.02.003 · Cited by 43
Lewy bodies in the sinoatrial nodal ganglion: Clinicopathological studies
Okada, Y., Ito, Y., Aida, J., Yasuhara, M., Ohkawa, S.-I., & Hirokawa, K. (2004) · Pathology International · doi:10.1111/j.1440-1827.2004.01680.x · Cited by 43
BLOOD PRESSURE AND VASOPRESSIN IN PROGRESSIVE AUTONOMIC FAILURE: RESPONSE TO POSTURAL STIMULATION, L-DOPA AND NALOXONE
Puritz, R., Lightman, S. L., Wilcox, C. S., Forsling, M. L., & Bannister, R. (1983) · Brain · doi:10.1093/brain/106.2.503 · Cited by 40
Dorsomedial hypothalamus mediates autonomic, neuroendocrine, and locomotor responses evoked from the medial preoptic area
Hunt, J. L., Zaretsky, D. V., Sarkar, S., & DiMicco, J. A. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00574.2009 · Cited by 40
Depletion of corticotrophin‐releasing factor neurons in the pontine micturition area in multiple system atrophy
Benarroch, E. E., & Schmeichel, A. M. (2001) · Annals of Neurology · doi:10.1002/ana.1258 · Cited by 38
Self-citation
Brainstem cells of origin of physiologically identified cardiopulmonary nerves in the rhesus monkey (Macaca mulatta)
Hopkins, D. A., & Armour, J. A. (1998) · Journal of the Autonomic Nervous System · doi:10.1016/s0165-1838(97)00112-4 · Cited by 36
Decreased cardiac MIBG uptake, its correlation with clinical symptoms in dementia with Lewy bodies
Kobayashi, S., Tateno, M., Morii, H., Utsumi, K., & Saito, T. (2009) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2009.02.006 · Cited by 35
Neuropharmacologic Distinction of Neurogenic Orthostatic Hypotension Syndromes
Sharabi, Y., Eldadah, B. A., Li, S., Dendi, R., Pechnik, S., Holmes, C. S., & Goldstein, D. S. (2006) · Clinical Neuropharmacology · doi:10.1097/01.wnf.0000220822.80640.0d · Cited by 34
Differential involvement of the periaqueductal gray in multiple system atrophy
Benarroch, E. E., Schmeichel, A. M., Low, P. A., & Parisi, J. E. (2010) · Autonomic Neuroscience · doi:10.1016/j.autneu.2010.07.009 · Cited by 32
Self-citation
Forebrain regions associated with postexercise differences in autonomic and cardiovascular function during baroreceptor unloading
Kimmerly, D. S., Wong, S. W. H., Salzer, D. A., Menon, R. S., & Shoemaker, J. K. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00044.2007 · Cited by 30
Skin vasomotor reflex responses in two contrasting groups of autonomic failure
Young, T., Asahina, M., Nicotra, A., & Mathias, C. J. (2006) · Journal of Neurology · doi:10.1007/s00415-006-0913-5 · Cited by 30
Brainstem-type Lewy body disease presenting with progressive autonomic failure and lethargy
Hishikawa, N., Hashizume, Y., Hirayama, M., Imamura, K., Washimi, Y., Koike, Y., Mabuchi, C., Yoshida, M., & Sobue, G. (2000) · Clinical Autonomic Research · doi:10.1007/bf02278018 · Cited by 27
Selective vulnerability of urinary Onuf motoneurons in Shy-Drager syndrome
Chalmers, D., & Swash, M. (1987) · Journal of Neurology · doi:10.1007/bf00618262 · Cited by 25
Low myocardial MIBG uptake in multiple system atrophy with incidental Lewy body pathology: An autopsy case report
Nagayama, H., Yamazaki, M., Ueda, M., Nishiyama, Y., Hamamoto, M., Katayama, Y., & Mori, O. (2008) · Movement Disorders · doi:10.1002/mds.22031 · Cited by 24
III. Morphometry of Myelinated Fibers of Rami Communicantes
Low, P. A., & Dyck, P. J. B. (1978) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197811000-00002 · Cited by 21
Abnormal baroreceptor-mediated vasopressin release as possible marker in early diagnosis of multiple system atrophy.
Deguchi, K., Sasaki, I., Touge, T., Tsukaguchi, M., Takeuchi, H., & Kuriyama, S. (2004) · PubMed Central · Cited by 20
Activation of the midbrain periaqueductal gray induces airway smooth muscle relaxation
Haxhiu, M. A., Yamamoto, B. K., Dreshaj, I. A., & Ferguson, D. G. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00752.2001 · Cited by 19
Abnormal suppression of arginine-vasopressin by clonidine in multiple system atrophy
Kimber, J., Watson, L. P. E., & Mathias, C. J. (1999) · Clinical Autonomic Research · doi:10.1007/bf02319457 · Cited by 13
Differential cardiac parasympathetic innervation—what is the functional significance?
Verberne, A. J. M. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00173.2004 · Cited by 6

Research works printed but not linked: 1

Jean, 1991, The nucleus tractus solitarius: neuroanatomic, neurochemical and functional aspects, Arch Int Physiol Biochim Biophys, 99, A3

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See all 129

Authors: Cersosimo, M. G., & Benarroch, E. E.
Affiliations: Universidad de Buenos Aires (AR)
Mayo Clinic (US)
Corresponding author: Eduardo Elias Benarroch
ORCID: Maria Graciela Cersosimo
Eduardo Elias Benarroch
Venue: Handbook of Clinical Neurology
Publisher: Elsevier
Published: 2013
Volume: 117
Pages: 45-57
ISSN: 0072-9752 (ISSN-L)
DOI: 10.1016/b978-0-444-53491-0.00005-5
OpenAlex: W104100557
Cited by: 129
References: 137
Citations by year: 2026: 6 · 2025: 8 · 2024: 9 · 2023: 13 · 2022: 7 · 2021: 18 · 2020: 13 · 2019: 10 · 2018: 6 · 2017: 12 · 2016: 8 · 2015: 12 · 2014: 7
FWCI: 24.87
Type: book chapter
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Handbook of clinical neurology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
Keywords: central autonomic network, autonomic dysfunction, neurodegenerative diseases, alpha-synuclein, multiple system atrophy, Lewy body disease, Parkinson's disease, dementia with Lewy bodies, pure autonomic failure, orthostatic hypotension, neurogenic bladder, dorsal motor nucleus of the vagus, enteric nervous system, rostral ventrolateral medulla, pre-Bötzinger complex, medullary raphe, sleep-wake cycle
MeSH terms: Afferent Pathways, Animals, Autonomic Nervous System, Autonomic Nervous System Diseases, Brain, Humans, Neurodegenerative Diseases

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Central control of autonomic function and involvement in neurodegenerative disorders

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