The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications
Open accessAbstract
Heparin plays an important role in many biological processes, via its interaction with various proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties such as anticoagulant activity, growth factor binding, as well as antiangiogenic and apoptotic effects, making them great candidates for emerging applications. Accordingly, this review summarizes recent efforts in the preparation of heparin-based hydrogels and formation of nanoparticles, as well as the characterization of their properties and applications. The challenges and future perspectives for heparin-based materials are also discussed. Prospects are promising for heparin-containing polymeric biomaterials in diverse applications ranging from cell carriers for promoting cell differentiation to nanoparticle therapeutics for cancer treatment.
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1 retracted
RETRACTED: Unclicking the Click: Mechanically Facilitated 1,3-Dipolar Cycloreversions
Brantley, J. N., Wiggins, K. M., & Bielawski, C. W. (2011) · Science · doi:10.1126/science.1207934 · Cited by 184
RetractedNanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Nanoparticle therapeutics: an emerging treatment modality for cancer
Davis, M. E., Chen, Z., & Shin, D. M. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2614 · Cited by 4,233
Impact of Nanotechnology on Drug Delivery
Farokhzad, O. C., & Langer, R. (2009) · ACS Nano · doi:10.1021/nn900002m · Cited by 3,348
Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications
Gao, J., Gu, H., & Xu, B. (2009) · Accounts of Chemical Research · doi:10.1021/ar9000026 · Cited by 1,907
Gold Nanoparticles in Biology: Beyond Toxicity to Cellular Imaging
Murphy, C. J., Gole, A. M., Stone, J. W., Sisco, P. N., Alkilany, A. M., Goldsmith, E. C., & Baxter, S. C. (2008) · Accounts of Chemical Research · doi:10.1021/ar800035u · Cited by 1,807
Polymeric system for dual growth factor delivery
Richardson, T. P., Peters, M. C., Ennett, A. B., & Mooney, D. J. (2001) · Nature Biotechnology · doi:10.1038/nbt1101-1029 · Cited by 1,752
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
Kloxin, A. M., Kasko, A. M., Salinas, C. N., & Anseth, K. S. (2009) · Science · doi:10.1126/science.1169494 · Cited by 1,748
Lutolf, M. P., Lauer-Fields, J. L., Schmoekel, H. G., Metters, A. T., Weber, F. E., Fields, G. B., & Hubbell, J. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0737381100 · Cited by 1,508
Future perspectives and recent advances in stimuli-responsive materials
Roy, D., Cambre, J. N., & Sumerlin, B. S. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.10.008 · Cited by 1,474
Cited by
Advancing biomaterials of human origin for tissue engineering
Chen, F.-M., & Liu, X. (2016) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2015.02.004 · Cited by 1,158
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Targeted Drug Delivery via the Use of ECM-Mimetic Materials
Hwang, J., Sullivan, M. O., & Kiick, K. L. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00069 · Cited by 76
Self-citationWang, L., Li, H., Chen, S., Nie, C., Cheng, C., & Zhao, C. (2015) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5b00320 · Cited by 33
Metadata
- Authors
- Liang, Y., & Kiick, K. L.
- Venue
- Acta Biomaterialia
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 10
- Issue
- 4
- Pages
- 1588-1600
- ISSN
- 1742-7061 (ISSN-L)
- OpenAlex
- W1997209259
- Cited by
- 349
- References
- 115
- FWCI
- 8.72
- Type
- journal article
- Language
- en
- Open access
- green
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- Liang, Y., & Kiick, K. L. (2014). Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2013.07.031
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.