CoChat
Sign Up
Cited by 76

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Targeted Drug Delivery via the Use of ECM-Mimetic Materials

Hwang, Jeongmin, Sullivan, Millicent O., Kiick, Kristi L.·2020·Frontiers in Bioengineering and Biotechnology
DOI 10.3389/fbioe.2020.00069PMC PMC7040483
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3389/fbioe.2020.00069

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Figures

FIGURE 1 Schematic overview of extracellular matrix components and their cell surface receptors (Theocharis et al., 2016). Copyright 2016. Reproduced with permission from Elsevier Inc. Cells have specific surface receptors, such as integrins, cell surface proteoglycans (ex. syndecans and glypicans), the HA receptor CD44, and DDRs, to bind ECM components for regulation of various cellular functions.
FIGURE 1 Schematic overview of extracellular matrix components and their cell surface receptors (Theocharis et al., 2016). Copyright 2016. Reproduced with permission from Elsevier Inc. Cells have specific surface receptors, such as integrins, cell surface proteoglycans (ex. syndecans and glypicans), the HA receptor CD44, and DDRs, to bind ECM components for regulation of various cellular functions.CC BY · PubMed Central
FIGURE 2 Extracellular matrix-based targeted delivery of particle-based DDS. (A) Schematic of ELP-CLP conjugate-based thermoresponsive nanovesicles (Luo et al., 2017). Copyright 2017. Reproduced with permission from American chemical society. (B) RGD dendrimer peptide modified polyethyleneimine-grafted chitosan for siRNA delivery. In vivo tumor growth of treatment with non-RGD-modified system (PgWSC) and RGD-modified system (RpgWSC), and non-treatment (Y.M. Kim et al., 2017). Copyright 2017. Reproduced with permission from Elsevier Inc. (C) Confocal images of internalization of dendrimer particles (CMCht/PAMAM and YIGSR-CMCht/PAMAM) on HCT-116 cancer cells (red) and L929 fibroblasts (blue) (Carvalho et al., 2019). Copyright Wiley-VCH Verlag GmbH. & Co. KGaA. Reproduced with permission.
FIGURE 2 Extracellular matrix-based targeted delivery of particle-based DDS. (A) Schematic of ELP-CLP conjugate-based thermoresponsive nanovesicles (Luo et al., 2017). Copyright 2017. Reproduced with permission from American chemical society. (B) RGD dendrimer peptide modified polyethyleneimine-grafted chitosan for siRNA delivery. In vivo tumor growth of treatment with non-RGD-modified system (PgWSC) and RGD-modified system (RpgWSC), and non-treatment (Y.M. Kim et al., 2017). Copyright 2017. Reproduced with permission from Elsevier Inc. (C) Confocal images of internalization of dendrimer particles (CMCht/PAMAM and YIGSR-CMCht/PAMAM) on HCT-116 cancer cells (red) and L929 fibroblasts (blue) (Carvalho et al., 2019). Copyright Wiley-VCH Verlag GmbH. & Co. KGaA. Reproduced with permission.CC BY · PubMed Central
FIGURE 3 Simple diffusion of drugs from ECM based matrices. (A) Computed tomography (CT) images for the efficacy of INFUSE® Bone Graft in clinical applications (McKay et al., 2007). Copyright 2007. Reproduced with permission from Springer Nature. (B) The scheme of overall study design. Histologic analysis using H&E, Saf-O/FG, and Gram staining of femurs after treating with hydrogel (UAMS-1), Lysostaphin-delivering hydrogel (UAMS-1 + Lst), and Lysostaphin, and sterilization (Johnson et al., 2018). Copyright 2018. Reproduced with permission from the National Academy of Sciences.
FIGURE 3 Simple diffusion of drugs from ECM based matrices. (A) Computed tomography (CT) images for the efficacy of INFUSE® Bone Graft in clinical applications (McKay et al., 2007). Copyright 2007. Reproduced with permission from Springer Nature. (B) The scheme of overall study design. Histologic analysis using H&E, Saf-O/FG, and Gram staining of femurs after treating with hydrogel (UAMS-1), Lysostaphin-delivering hydrogel (UAMS-1 + Lst), and Lysostaphin, and sterilization (Johnson et al., 2018). Copyright 2018. Reproduced with permission from the National Academy of Sciences.CC BY · PubMed Central
FIGURE 4 Extracellular matrix-based matrices and drug interaction-based delivery systems. (A) Growth factor retention in fibrin matrices with laminin-mimetic peptides (α2PI1–8-LAMA33043–3067 or α2PI1–8-LAMA53417–3436) or without peptide (**p < 0.01) (Ishihara et al., 2018). Copyright 2018. Reproduced with permission from Springer Nature. (B) The scheme of study design. Antimicrobial activity of LL37 and with collagen-binding domains (cCBD-LL37 or fCBD-LL37) on collagen scaffold after 12 h and 14 days (*p < 0.01, **p < 0.001, +p < 0.05) (Lozeau et al., 2017). Copyright 2017. Reproduced with permission from Elsevier Inc.
FIGURE 4 Extracellular matrix-based matrices and drug interaction-based delivery systems. (A) Growth factor retention in fibrin matrices with laminin-mimetic peptides (α2PI1–8-LAMA33043–3067 or α2PI1–8-LAMA53417–3436) or without peptide (**p < 0.01) (Ishihara et al., 2018). Copyright 2018. Reproduced with permission from Springer Nature. (B) The scheme of study design. Antimicrobial activity of LL37 and with collagen-binding domains (cCBD-LL37 or fCBD-LL37) on collagen scaffold after 12 h and 14 days (*p < 0.01, **p < 0.001, +p < 0.05) (Lozeau et al., 2017). Copyright 2017. Reproduced with permission from Elsevier Inc.CC BY · PubMed Central
FIGURE 5 Polyplex immobilized in an ECM-based matrix for gene delivery. (A) Flow-activated cell sorting (FACS) analysis of biotin-functionalized pGFP polyplex immobilized in avidin-modified collagen hydrogel through avidin-biotin interaction (right graph) and avidin-free collagen hydrogel (left) (Orsi et al., 2010). Copyright 2010. Reproduced with permission from Elsevier Inc. (B) pGluc expression for 30 days of cell culture in the presence of immobilized pGluc polyplex on the surface of hyaluronic acid hydrogel through electrostatic interaction, and bolus transfection controls (Truong and Segura, 2018). Copyright 2018. Reproduced with permission from the American Chemical Society. (C) pGluc expression of immobilized GPP-PEI in the collagen hydrogel and free GPP polyplex in hydrogel after a week of pre-incubation in media with and without the presence of metalloproteinase (Urello et al., 2014). Copyright 2014. Reproduced with permission from The Royal Society of Chemistry. (D) Colocalization study of FITC labeled collagen (Green) with Alexa Fluor 350 labeled GPP-PEI (Blue) in NIH3T3 cells after 5 days of pre-incubation in the media (Urello et al., 2017). The scale bar is 25 μm. Copyright 2017. Reproduced with permission from Elsevier Inc.
FIGURE 5 Polyplex immobilized in an ECM-based matrix for gene delivery. (A) Flow-activated cell sorting (FACS) analysis of biotin-functionalized pGFP polyplex immobilized in avidin-modified collagen hydrogel through avidin-biotin interaction (right graph) and avidin-free collagen hydrogel (left) (Orsi et al., 2010). Copyright 2010. Reproduced with permission from Elsevier Inc. (B) pGluc expression for 30 days of cell culture in the presence of immobilized pGluc polyplex on the surface of hyaluronic acid hydrogel through electrostatic interaction, and bolus transfection controls (Truong and Segura, 2018). Copyright 2018. Reproduced with permission from the American Chemical Society. (C) pGluc expression of immobilized GPP-PEI in the collagen hydrogel and free GPP polyplex in hydrogel after a week of pre-incubation in media with and without the presence of metalloproteinase (Urello et al., 2014). Copyright 2014. Reproduced with permission from The Royal Society of Chemistry. (D) Colocalization study of FITC labeled collagen (Green) with Alexa Fluor 350 labeled GPP-PEI (Blue) in NIH3T3 cells after 5 days of pre-incubation in the media (Urello et al., 2017). The scale bar is 25 μm. Copyright 2017. Reproduced with permission from Elsevier Inc.CC BY · PubMed Central

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 8 references

Research works printed but not linked: 190

  1. Aderem, 1999, Mechanisms of phagocytosis in macrophages., Annu. Rev. Immunol., 17, 593, 10.1146/annurev.immunol.17.1.593 · DOI · Paper page
  2. Alam, 2007, The integrin-growth factor receptor duet., J. Cell Physiol., 213, 649, 10.1002/jcp.21278 · DOI
  3. Allen, 2004, Drug delivery systems: entering the mainstream., Science, 303, 1818, 10.1126/science.1095833 · DOI · Paper page
  4. An, 2016, Collagen binding to OSCAR: the odd couple., Blood, 127, 521, 10.1182/blood-2015-12-682476 · DOI
  5. Appel, 2015, Self-assembled hydrogels utilizing polymer-nanoparticle interactions., Nat. Commun., 6, 10.1038/ncomms7295 · DOI
  6. Arap, 1998, Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model., Science, 279, 377, 10.1126/science.279.5349.377 · DOI
  7. Arora, 2013, Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions., Mol. Biol. Cell, 24, 734, 10.1091/mbc.E12-10-0754 · DOI
  8. Belting, 2003, Heparan sulfate proteoglycan as a plasma membrane carrier., Trends Biochem. Sci., 28, 145, 10.1016/S0968-0004(03)00031-8 · DOI · Paper page
  9. Bhakta, 2013, The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formation., Acta Biomater., 9, 9098, 10.1016/j.actbio.2013.07.008 · DOI
  10. Bibby, 2005, Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice., Int. J. Pharm., 293, 281, 10.1016/j.ijpharm.2004.12.021 · DOI
  11. Blanco, 2015, Principles of nanoparticle design for overcoming biological barriers to drug delivery., Nat. Biotechnol., 33, 941, 10.1038/nbt.3330 · DOI · Paper page
  12. Boekhoven, 2014, 25th anniversary article: supramolecular materials for regenerative medicine., Adv. Mater., 26, 1642, 10.1002/adma.201304606 · DOI
  13. Cai, 2014, Designing ECM-mimetic materials using protein engineering., Acta Biomater., 10, 1751, 10.1016/j.actbio.2013.12.028 · DOI
  14. Caliari, 2016, A practical guide to hydrogels for cell culture., Nat. Methods, 13, 405, 10.1038/nmeth.3839 · DOI · Paper page
  15. Carvalho, 2019, Peptide-modified dendrimer nanoparticles for targeted therapy of colorectal cancer., Adv. Ther., 2, 10.1002/adtp.201900132 · DOI
  16. Cervadoro, 2018, Targeting inflammation with nanosized drug delivery platforms in cardiovascular diseases: immune cell modulation in atherosclerosis., Front. Bioeng. Biotechnol., 6, 10.3389/fbioe.2018.00177 · DOI
  17. Chia, 2014, The use of Collatamp G, local gentamicin-collagen sponge, in reducing wound infection., Int. Surg., 99, 565, 10.9738/INTSURG-D-13-00171.1 · DOI
  18. Chowdhury, 2006, Fibronectin-coated nano-precipitates of calcium-magnesium phosphate for integrin-targeted gene delivery., J. Control Release, 116, e68, 10.1016/j.jconrel.2006.09.054 · DOI
  19. Christman, 2011, Protein nanopatterns by oxime bond formation., Langmuir, 27, 1415, 10.1021/la103978x · DOI
  20. Chung, 2010, The effect of surface functionalization of PLGA nanoparticles by heparin- or chitosan-conjugated Pluronic on tumor targeting., J. Control Release, 143, 374, 10.1016/j.jconrel.2010.01.017 · DOI
  21. Cichy, 2003, The liberation of CD44., J. Cell Biol., 161, 839, 10.1083/jcb.200302098 · DOI
  22. Colognato, 2000, Form and function: the laminin family of heterotrimers., Dev. Dyn., 218, 213, 10.1002/(SICI)1097-0177(200006)218:2<213::AID-DVDY1>3.0.CO;2-R · DOI
  23. Coopman, 1996, Integrin alpha 3 beta 1 participates in the phagocytosis of extracellular matrix molecules by human breast cancer cells., Mol. Biol. Cell, 7, 1789, 10.1091/mbc.7.11.1789 · DOI
  24. Crapo, 2011, An overview of tissue and whole organ decellularization processes., Biomaterials, 32, 3233, 10.1016/j.biomaterials.2011.01.057 · DOI · Paper page
  25. Danhier, 2010, To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery., J. Control Release, 148, 135, 10.1016/j.jconrel.2010.08.027 · DOI
  26. Danhier, 2012, RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis., Mol. Pharm., 9, 2961, 10.1021/mp3002733 · DOI
  27. Das, 2017, Characterization of laminin binding integrin internalization in prostate cancer cells., J. Cell Biochem., 118, 1038, 10.1002/jcb.25673 · DOI
  28. de Bruin, 2010, Local application of gentamicin collagen implants in the prophylaxis of surgical site infections following gastrointestinal surgery: a review of clinical experience., Tech. Coloproctol., 14, 301, 10.1007/s10151-010-0593-0 · DOI
  29. De Laporte, 2007, Matrices and scaffolds for DNA delivery in tissue engineering., Adv. Drug Deliv. Rev., 59, 292, 10.1016/j.addr.2007.03.017 · DOI
  30. De Souza, 2010, Polymeric drug delivery systems for localized cancer chemotherapy., Drug Deliv., 17, 365, 10.3109/10717541003762854 · DOI
  31. Dimatteo, 2018, In situ forming injectable hydrogels for drug delivery and wound repair., Adv. Drug Deliv. Rev., 127, 167, 10.1016/j.addr.2018.03.007 · DOI
  32. Dosio, 2016, Hyaluronic acid for anticancer drug and nucleic acid delivery., Adv. Drug Deliv. Rev., 97, 204, 10.1016/j.addr.2015.11.011 · DOI
  33. D’Souza, 2015, Asialoglycoprotein receptor mediated hepatocyte targeting - strategies and applications., J. Control Release, 203, 126, 10.1016/j.jconrel.2015.02.022 · DOI
  34. Dubey, 2010, . Polymeric nanospheres modified with YIGSR peptide for tumor targeting., Drug. Deliv., 17, 541, 10.3109/10717544.2010.490249 · DOI
  35. Dunehoo, 2006, Cell adhesion molecules for targeted drug delivery., J. Pharm. Sci., 95, 1856, 10.1002/jps.20676 · DOI
  36. Duxfield, 2016, . Ocular delivery systems for topical application of anti-infective agents., Drug. Dev. Ind. Pharm., 42, 1, 10.3109/03639045.2015.1070171 · DOI
  37. Elangovan, 2014, The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor., Biomaterials, 35, 737, 10.1016/j.biomaterials.2013.10.021 · DOI
  38. Eliaz, 2001, Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells., Cancer Res., 61, 2592
  39. El-Sayed, 2013, Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis., Mol. Ther., 21, 1118, 10.1038/mt.2013.54 · DOI
  40. Fan, 2013, Ternary complexes with core-shell bilayer for double level targeted gene delivery: in vitro and in vivo evaluation., Pharm. Res., 30, 1215, 10.1007/s11095-012-0960-9 · DOI
  41. Farajzadeh, 2018, Macrophage repolarization using CD44-targeting hyaluronic acid-polylactide nanoparticles containing curcumin., Artif. Cells Nanomed Biotechnol., 46, 2013, 10.1080/21691401.2017.1408116 · DOI
  42. Farrukh, 2017, Bifunctional hydrogels containing the laminin Motif IKVAV promote neurogenesis., Stem Cell Rep., 9, 1432, 10.1016/j.stemcr.2017.09.002 · DOI
  43. Foroozandeh, 2018, Insight into cellular uptake and intracellular trafficking of nanoparticles., Nanoscale Res. Lett., 13, 10.1186/s11671-018-2728-6 · DOI
  44. Freudenberg, 2016, Glycosaminoglycan-based biohybrid hydrogels: a sweet and smart choice for multifunctional biomaterials., Adv. Mater., 28, 8861, 10.1002/adma.201601908 · DOI
  45. Freudenberg, 2015, Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds., J. Control Release, 220, 79, 10.1016/j.jconrel.2015.10.028 · DOI
  46. Garber, 2018, Alnylam launches era of RNAi drugs., Nat. Biotechnol., 36, 777, 10.1038/nbt0918-777 · DOI
  47. Giancotti, 2003, A structural view of integrin activation and signaling., Dev. Cell, 4, 149, 10.1016/S1534-5807(03)00034-0 · DOI
  48. Giancotti, 1999, Integrin signaling., Science, 285, 1028, 10.1126/science.285.5430.1028 · DOI · Paper page
  49. Goebeler, 1996, Migration of highly aggressive melanoma cells on hyaluronic acid is associated with functional changes, increased turnover and shedding of CD44 receptors., J. Cell Sci., 109, 1957, 10.1242/jcs.109.7.1957 · DOI
  50. Goodman, 2012, Integrins as therapeutic targets., Trends Pharmacol. Sci., 33, 405, 10.1016/j.tips.2012.04.002 · DOI
  51. Gospodarowicz, 1986, Heparin protects basic and acidic FGF from inactivation., J. Cell Physiol., 128, 475, 10.1002/jcp.1041280317 · DOI · Paper page
  52. Graf, 1987, Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding., Cell, 48, 989, 10.1016/0092-8674(87)90707-0 · DOI
  53. Guo, 2010, Enhanced angiogenesis of gene-activated dermal equivalent for treatment of full thickness incisional wounds in a porcine model., Biomaterials, 31, 7308, 10.1016/j.biomaterials.2010.06.013 · DOI
  54. Hamano, 2012, Modification of the C16Y peptide on nanoparticles is an effective approach to target endothelial and cancer cells via the integrin receptor., Int. J. Pharm., 428, 114, 10.1016/j.ijpharm.2012.02.006 · DOI
  55. Harburger, 2009, Integrin signalling at a glance., J. Cell Sci., 122, 159, 10.1242/jcs.018093 · DOI
  56. Hendricks, 2017, Supramolecular Assembly of Peptide Amphiphiles., Acc. Chem. Res., 50, 2440, 10.1021/acs.accounts.7b00297 · DOI
  57. Hernandez, 2018, Decellularized extracellular matrix hydrogels as a delivery platform for MicroRNA and extracellular vesicle therapeutics., Adv. Ther., 1
  58. Highley, 2016, Recent advances in hyaluronic acid hydrogels for biomedical applications., Curr. Opin. Biotechnol., 40, 35, 10.1016/j.copbio.2016.02.008 · DOI
  59. Hinderer, 2016, ECM and ECM-like materials - Biomaterials for applications in regenerative medicine and cancer therapy., Adv. Drug. Deliv. Rev., 97, 260, 10.1016/j.addr.2015.11.019 · DOI · Paper page
  60. Hoffman, 2001, Cell type-specific differences in glycosaminoglycans modulate the biological activity of a heparin-binding peptide (RKRLQVQLSIRT) from the G domain of the laminin alpha1 chain., J. Biol. Chem., 276, 22077, 10.1074/jbc.M100774200 · DOI
  61. Hu, 2018, iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery., Nanoscale, 10, 10514, 10.1039/c8nr02534g · DOI
  62. Hu, 2016, Recent advances of cocktail chemotherapy by combination drug delivery systems., Adv. Drug. Deliv. Rev., 98, 19, 10.1016/j.addr.2015.10.022 · DOI · Paper page
  63. Huang, 2018, Hyaluronic acid-based biopharmaceutical delivery and tumor-targeted drug delivery system., J. Control Release, 278, 122, 10.1016/j.jconrel.2018.04.015 · DOI
  64. Hwang, 2016, Failure of investigational drugs in late-stage clinical development and publication of trial results., JAMA Intern. Med., 176, 1826, 10.1001/jamainternmed.2016.6008 · DOI
  65. Ishihara, 2018, Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing., Nat. Commun., 9, 10.1038/s41467-018-04525-w · DOI
  66. Jeong, 2009, Interplay between covalent and physical interactions within environment sensitive hydrogels., Biomacromolecules, 10, 1090, 10.1021/bm801270k · DOI
  67. Jiang, 2011, Hyaluronan as an immune regulator in human diseases., Physiol. Rev., 91, 221, 10.1152/physrev.00052.2009 · DOI · Paper page
  68. Jiao, 2016, Advances in hyaluronic acid-based drug delivery systems., Curr. Drug. Targets, 17, 720, 10.1152/physrev.00052.2009 · DOI · Paper page
  69. Johnson, 2018, Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing., Proc. Natl. Acad. Sci. U.S.A., 115, E4960, 10.1073/pnas.1801013115 · DOI
  70. Kharkar, 2013, Designing degradable hydrogels for orthogonal control of cell microenvironments., Chem. Soc. Rev., 42, 7335, 10.1039/c3cs60040h · DOI · Paper page
  71. Kim, 2011, Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor., J. Endocrinol., 209, 139, 10.1530/JOE-10-0377 · DOI
  72. Kim, 2017, Targeted gene delivery of polyethyleneimine-grafted chitosan with RGD dendrimer peptide in alphavbeta3 integrin-overexpressing tumor cells., Carbohydr. Polym., 174, 1059, 10.1016/j.carbpol.2017.07.035 · DOI
  73. Kohane, 2008, Hydrogels in drug delivery: progress and challenges., polymer, 49, 1993, 10.1016/j.polymer.2008.01.027 · DOI
  74. Kolmel, 2017, Oximes and hydrazones in bioconjugation: mechanism and catalysis., Chem. Rev., 117, 10358, 10.1021/acs.chemrev.7b00090 · DOI
  75. Lallana, 2017, Chitosan/hyaluronic acid nanoparticles: rational design revisited for RNA delivery., Mol. Pharm., 14, 2422, 10.1021/acs.molpharmaceut.7b00320 · DOI
  76. Langer, 1998, Drug delivery and targeting., Nature, 392, 5
  77. Leitinger, 2014, Discoidin domain receptor functions in physiological and pathological conditions., Int. Rev. Cell Mol. Biol., 310, 39, 10.1016/B978-0-12-800180-6.00002-5 · DOI
  78. Leitinger, 2007, Mammalian collagen receptors., Matrix. Biol., 26, 146, 10.1016/j.matbio.2006.10.007 · DOI
  79. Leonoudakis, 2014, Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers., J. Cell Sci., 127, 4894, 10.1242/jcs.152728 · DOI
  80. Li, 2016, Designing hydrogels for controlled drug delivery., Nat. Rev. Mater., 1, 10.1038/natrevmats.2016.71 · DOI
  81. Liang, 2014, Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications., Acta Biomater., 10, 1588, 10.1016/j.actbio.2013.07.031 · DOI
  82. Liu, 2016, The smart drug delivery system and its clinical potential., Theranostics, 6, 1306, 10.7150/thno.14858 · DOI · Paper page
  83. Lobert, 2010, Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes., Dev. Cell, 19, 148, 10.1016/j.devcel.2010.06.010 · DOI
  84. Lohmann, 2017, Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice., Sci. Transl. Med., 9, 10.1126/scitranslmed.aai9044 · DOI
  85. Lozeau, 2017, Collagen tethering of synthetic human antimicrobial peptides cathelicidin LL37 and its effects on antimicrobial activity and cytotoxicity., Acta Biomater., 52, 9, 10.1016/j.actbio.2016.12.047 · DOI
  86. Luo, 2017, Thermoresponsive Elastin-b-Collagen-Like peptide bioconjugate nanovesicles for targeted drug delivery to collagen-containing matrices., Biomacromolecules, 18, 2539, 10.1021/acs.biomac.7b00686 · DOI
  87. Lutolf, 2003, Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics., Proc. Natl. Acad. Sci. U.S.A., 100, 5413, 10.1073/pnas.0737381100 · DOI · Paper page
  88. Madsen, 2011, The non-phagocytic route of collagen uptake: a distinct degradation pathway., J. Biol. Chem., 286, 26996, 10.1074/jbc.M110.208033 · DOI
  89. Mao, 2009, Enhanced angiogenesis of porous collagen scaffolds by incorporation of TMC/DNA complexes encoding vascular endothelial growth factor., Acta Biomater., 5, 2983, 10.1016/j.actbio.2009.04.004 · DOI
  90. Massia, 1992, Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin alpha 4 beta 1., J. Biol. Chem., 267, 14019, 10.1016/S0021-9258(19)49672-5 · DOI · Paper page
  91. Mateen, 2014, Injectable, in situ gelling, cyclodextrin-dextran hydrogels for the partitioning-driven release of hydrophobic drugs., Mater J. Chem. B, 2, 5157, 10.1039/C4TB00631C · DOI
  92. McBrien, 2006, Expression of collagen-binding integrin receptors in the mammalian sclera and their regulation during the development of myopia., Invest. Ophthalmol. Vis. Sci., 47, 4674, 10.1167/iovs.05-1150 · DOI
  93. McKay, 2007, A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft)., Int. Orthop., 31, 729, 10.1007/s00264-007-0418-6 · DOI
  94. Meneghetti, 2015, Heparan sulfate and heparin interactions with proteins., J. R. Soc. Interface, 12, 10.1098/rsif.2015.0589 · DOI
  95. Merino, 2015, Nanocomposite hydrogels: 3D polymer-nanoparticle synergies for on-demand drug delivery., ACS Nano, 9, 4686, 10.1021/acsnano.5b01433 · DOI
  96. Miyazaki, 2018, Hyaluronic acid-based pH-sensitive polymer-modified liposomes for cell-specific intracellular drug delivery systems., Bioconjug Chem., 29, 44, 10.1021/acs.bioconjchem.7b00551 · DOI
  97. Morrison, 2018, Alnylam prepares to land first RNAi drug approval., Nat. Rev. Drug Discov., 17, 156, 10.1038/nrd.2018.20 · DOI
  98. Mould, 1991, The CS5 peptide is a second site in the IIICS region of fibronectin recognized by the integrin alpha 4 beta 1. Inhibition of alpha 4 beta 1 function by RGD peptide homologues., J. Biol. Chem., 266, 3579, 10.1016/S0021-9258(19)67834-8 · DOI
  99. Munsell, 2016, Journey to the Center Of The Cell: Current Nanocarrier Design Strategies Targeting Biopharmaceuticals To The Cytoplasm And Nucleus., Curr. Pharm. Des., 22, 1227, 10.1152/physrev.00052.2009 · DOI · Paper page
  100. Murphy, 2008, Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis., Proc. Natl. Acad. Sci. U.S.A., 105, 9343, 10.1073/pnas.0803728105 · DOI
  101. Mythreye, 2009, Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion., Cell Signal., 21, 1548, 10.1016/j.cellsig.2009.05.001 · DOI
  102. Narayanaswamy, 2019, Hydrogels and their applications in targeted drug delivery., Molecules, 24, 10.3390/molecules24030603 · DOI · Paper page
  103. Ndinguri, 2012, Application of collagen-model triple-helical peptide-amphiphiles for CD44-TARGETED DRUG DELIVERY SYStems., J. Drug. Deliv., 2012, 10.1155/2012/592602 · DOI
  104. Negishi, 2011, Effects of doxorubicin-encapsulating AG73 peptide-modified liposomes on tumor selectivity and cytotoxicity., Results Pharm. Sci., 1, 68, 10.1016/j.rinphs.2011.10.001 · DOI
  105. Negishi, 2019, Laminin-derived peptides: applications in drug delivery systems for targeting., Pharmacol. Ther., 202, 91, 10.1016/j.pharmthera.2019.05.017 · DOI
  106. Negishi, 2010, Preparation and characterization of laminin-derived peptide AG73-coated liposomes as a selective gene delivery tool., Biol. Pharm. Bull, 33, 1766, 10.1248/bpb.33.1766 · DOI
  107. Nielsen, 2017, The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers., Oncotarget, 8, 44605, 10.18632/oncotarget.17883 · DOI
  108. Nieto Gutierrez, 2018, GPCRs: emerging anti-cancer drug targets., Cell Signal., 41, 65, 10.1016/j.cellsig.2017.09.005 · DOI
  109. Nikam, 2018, Journey of siRNA: clinical developments and targeted delivery., Nucleic Acid Ther., 28, 209, 10.1089/nat.2017.0715 · DOI
  110. Oh, 2010, Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives., J. Control Release, 141, 2, 10.1016/j.jconrel.2009.09.010 · DOI
  111. Okur, 2016, Targeting cancer cells via tumor-homing peptide CREKA functional PEG nanoparticles., Coll. Surf. B Biointerf, 147, 191, 10.1016/j.colsurfb.2016.08.005 · DOI · Paper page
  112. Oliva, 2017, Designing hydrogels for on-demand therapy., Acc. Chem. Res., 50, 669, 10.1021/acs.accounts.6b00536 · DOI
  113. Oliviero, 2012, Functional porous hydrogels to study angiogenesis under the effect of controlled release of vascular endothelial growth factor., Acta Biomater., 8, 3294, 10.1016/j.actbio.2012.05.019 · DOI
  114. Ooi, 2017, Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration., Mater. Horizons, 4, 1020, 10.1039/c7mh00373k · DOI
  115. Orsi, 2010, Cell recruitment and transfection in gene activated collagen matrix., Biomaterials, 31, 570, 10.1016/j.biomaterials.2009.09.054 · DOI
  116. Palmese, 2019, Hybrid hydrogels for biomedical applications., Curr. Opin.Chem. Eng., 24, 143, 10.1016/j.coche.2019.02.010 · DOI
  117. Pankov, 2002, Fibronectin at a glance., J. Cell Sci., 115, 3861, 10.1242/jcs.00059 · DOI
  118. Panyam, 2003, Biodegradable nanoparticles for drug and gene delivery to cells and tissue., Adv. Drug Deliv. Rev., 55, 329, 10.1016/S0169-409X(02)00228-4 · DOI
  119. Park, 2000, Type I atelocollagen grafting onto ozone-treated polyurethane films: cell attachment, proliferation, and collagen synthesis., J. Biomed Mater. Res., 52, 669, 10.1002/1097-4636(20001215)52:4<669::AID-JBM11>3.0.CO;2-U · DOI
  120. Park, 2017, Advanced growth factor delivery systems in wound management and skin regeneration., Molecules, 22, 10.3390/molecules22081259 · DOI
  121. Pathak, 2009, Gene expression, biodistribution, and pharmacoscintigraphic evaluation of chondroitin sulfate-PEI nanoconstructs mediated tumor gene therapy., ACS Nano, 3, 1493, 10.1021/nn900044f · DOI
  122. Patterson, 2010, Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2., Biomaterials, 31, 7836, 10.1016/j.biomaterials.2010.06.061 · DOI
  123. Phelps, 2012, Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery., Adv. Mater., 24, 64, 10.1002/adma.201103574 · DOI
  124. Phuc, 2017, Epidermal growth factor enhances cellular uptake of polystyrene nanoparticles by clathrin-mediated endocytosis., Int. J. Mol. Sci., 18, 10.3390/ijms18061301 · DOI
  125. Prasad, 2014, The withdrawal of drugs for commercial reasons: the incomplete story of tositumomab., JAMA Intern. Med., 174, 1887, 10.1001/jamainternmed.2014.5756 · DOI
  126. Prokoph, 2012, Sustained delivery of SDF-1alpha from heparin-based hydrogels to attract circulating pro-angiogenic cells., Biomaterials, 33, 4792, 10.1016/j.biomaterials.2012.03.039 · DOI
  127. Qureshi, 2011, Market withdrawal of new molecular entities approved in the United States from 1980 to 2009., Pharmacoepidemiol. Drug Saf., 20, 772, 10.1002/pds.2155 · DOI
  128. Raab-Westphal, 2017, Integrins as therapeutic targets: successes and cancers., Cancers, 9, 10.3390/cancers9090110 · DOI
  129. Raave, 2018, Chemotherapeutic drug delivery by tumoral extracellular matrix targeting., J. Control Release, 274, 1, 10.1016/j.jconrel.2018.01.029 · DOI · Paper page
  130. Racine, 2012, Hyaluronan endocytosis: mechanisms of uptake and biological functions, Molecular Regulation of Endocytosis, 377
  131. Rainero, 2016, Extracellular matrix endocytosis in controlling matrix turnover and beyond: emerging roles in cancer., Biochem. Soc. Trans., 44, 1347, 10.1042/BST20160159 · DOI
  132. Raja, 2012, Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection following cardiac surgery., Int. J. Surg., 10, S10, 10.1016/j.ijsu.2012.05.018 · DOI
  133. Ramshaw, 2009, Collagens as biomaterials., J. Mater. Sci. Mater. Med., 20, S3, 10.1007/s10856-008-3415-4 · DOI
  134. Reilly, 2012, Polyplexes traffic through caveolae to the Golgi and endoplasmic reticulum en route to the nucleus., Mol. Pharm., 9, 1280, 10.1021/mp200583d · DOI
  135. Rejman, 2005, Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes., Mol. Ther., 12, 468, 10.1016/j.ymthe.2005.03.038 · DOI
  136. Rezler, 2007, Targeted drug delivery utilizing protein-like molecular architecture., J. Am. Chem. Soc., 129, 10.1021/ja066929m · DOI
  137. Roggenbuck, 2012, Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity., Auto Immun. Highlights, 3, 119, 10.1007/s13317-012-0041-4 · DOI
  138. Rosso, 2004, From cell-ECM interactions to tissue engineering., J. Cell Physiol., 199, 174, 10.1002/jcp.10471 · DOI
  139. Ruoslahti, 2002, Drug targeting to specific vascular sites., Drug Discov. Today, 7, 1138, 10.1016/S1359-6446(02)02501-1 · DOI
  140. Ruoslahti, 1986, Arg-Gly-Asp: a versatile cell recognition signal., Cell, 44, 517, 10.1016/0092-8674(86)90259-x · DOI
  141. Ruskowitz, 2018, Photoresponsive biomaterials for targeted drug delivery and 4D cell culture., Nat. Rev. Mater., 3, 1, 10.1038/natrevmats2017.87 · DOI
  142. Sahay, 2010, Endocytosis of nanomedicines., J. Control Release, 145, 182, 10.1016/j.jconrel.2010.01.036 · DOI · Paper page
  143. Sakiyama-Elbert, 2000, Development of fibrin derivatives for controlled release of heparin-binding growth factors., J. Control Release, 65, 389, 10.1016/s0168-3659(99)00221-7 · DOI
  144. Saldin, 2017, Extracellular matrix hydrogels from decellularized tissues: Structure and function., Acta Biomater., 49, 1, 10.1016/j.actbio.2016.11.068 · DOI
  145. Sato, 2018, Peptide supramolecular materials for therapeutics., Chem. Soc. Rev., 47, 7539, 10.1039/c7cs00735c · DOI
  146. Schiffelers, 2004, Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle., Nucleic Acids Res., 32, 10.1093/nar/gnh140 · DOI
  147. Schnittert, 2018, Integrins in wound healing, fibrosis and tumor stroma: high potential targets for therapeutics and drug delivery., Adv. Drug Deliv. Rev., 129, 37, 10.1016/j.addr.2018.01.020 · DOI
  148. Seif-Naraghi, 2012, Injectable extracellular matrix derived hydrogel provides a platform for enhanced retention and delivery of a heparin-binding growth factor., Acta Biomater., 8, 3695, 10.1016/j.actbio.2012.06.030 · DOI
  149. She, 2013, Dendronized heparin-doxorubicin conjugate based nanoparticle as pH-responsive drug delivery system for cancer therapy., Biomaterials, 34, 2252, 10.1016/j.biomaterials.2012.12.017 · DOI
  150. Sheikhpour, 2017, Biomimetics in drug delivery systems: a critical review., J. Control Release, 253, 97, 10.1016/j.jconrel.2017.03.026 · DOI
  151. Shekaran, 2014, Bone regeneration using an alpha 2 beta 1 integrin-specific hydrogel as a BMP-2 delivery vehicle., Biomaterials, 35, 5453, 10.1016/j.biomaterials.2014.03.055 · DOI
  152. Shi, 2008, Caveolin-1-dependent beta1 integrin endocytosis is a critical regulator of fibronectin turnover., J. Cell Sci., 121, 2360, 10.1242/jcs.014977 · DOI
  153. Shing, 1984, Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor., Science, 223, 1296, 10.1126/science.6199844 · DOI
  154. Shukla, 2012, Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer., Proc. Natl. Acad. Sci. U.S.A., 109, 12426, 10.1073/pnas.1121174109 · DOI
  155. Silva, 2004, Selective differentiation of neural progenitor cells by high-epitope density nanofibers., Science, 303, 1352, 10.1126/science.1093783 · DOI
  156. Sood, 2016, Stimuli-responsive hydrogels in drug delivery and tissue engineering., Drug Deliv., 23, 758, 10.3109/10717544.2014.940091 · DOI · Paper page
  157. Storrie, 2007, Supramolecular crafting of cell adhesion., Biomaterials, 28, 4608, 10.1016/j.biomaterials.2007.06.026 · DOI
  158. Tanihara, 2001, Sustained release of basic fibroblast growth factor and angiogenesis in a novel covalently crosslinked gel of heparin and alginate., J. Biomed Mater. Res., 56, 216, 10.1002/1097-4636(200108)56:2<216::AID-JBM1086>3.0.CO;2-N · DOI
  159. Tashiro, 1989, A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth., J. Biol. Chem., 264, 16174, 10.1016/S0021-9258(18)71604-9 · DOI
  160. Tibbitt, 2016, Emerging frontiers in drug delivery., J. Am. Chem. Soc., 138, 704, 10.1021/jacs.5b09974 · DOI
  161. Torchilin, 2014, Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery., Nat. Rev. Drug Discov., 13, 813, 10.1038/nrd4333 · DOI
  162. Tripodo, 2015, Hyaluronic acid and its derivatives in drug delivery and imaging: recent advances and challenges., Eur. J. Pharm. Biopharm., 97, 400, 10.1016/j.ejpb.2015.03.032 · DOI
  163. Truong, 2019, Pathways governing polyethylenimine polyplex transfection in microporous annealed particle scaffolds., Bioconjug Chem., 30, 476, 10.1021/acs.bioconjchem.8b00696 · DOI
  164. Truong, 2018, Sustained transgene expression via hydrogel-mediated gene transfer results from multiple transfection events., ACS Biomater. Sci. Eng, 4, 981, 10.1021/acsbiomaterials.7b00957 · DOI
  165. Tsuji, 2013, Endocytic mechanism of transferrin-conjugated nanoparticles and the effects of their size and ligand number on the efficiency of drug delivery., Microscopy, 62, 341, 10.1093/jmicro/dfs080 · DOI
  166. Tsurkan, 2013, Growth factor delivery from hydrogel particle aggregates to promote tubular regeneration after acute kidney injury., J. Control Release, 2013, 248, 10.1016/j.jconrel.2013.01.030 · DOI
  167. Ulrich, 2014, Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs., Chemistry, 20, 34, 10.1002/chem.201302426 · DOI
  168. Urello, 2016, Integration of growth factor gene delivery with collagen-triggered wound repair cascades using collagen-mimetic peptides., Bioeng Transl. Med., 1, 207, 10.1002/btm2.10037 · DOI
  169. Urello, 2017, ECM turnover-stimulated gene delivery through collagen-mimetic peptide-plasmid integration in collagen., Acta Biomater., 62, 167, 10.1016/j.actbio.2017.08.038 · DOI
  170. Urello, 2014, A CMP-based method for tunable, cell-mediated gene delivery from collagen scaffolds., Mater. J. Chem. B, 8174, 10.1039/c4tb01435a · DOI
  171. Wang, 2014, Design of gene-activated matrix for the repair skin and cartilage., Polym. J., 46, 476, 10.1038/pj.2014.50 · DOI
  172. Wang, 2015, Targeting REDV peptide functionalized polycationic gene carrier for enhancing the transfection and migration capability of human endothelial cells., J. Mater. Chem. B, 3, 3379, 10.1039/C4TB02019G · DOI
  173. Wang, 2018, Programmable hydrogels., Biomaterials, 178, 663, 10.1016/j.biomaterials.2018.03.008 · DOI
  174. Webber, 2010, Development of bioactive peptide amphiphiles for therapeutic cell delivery., Acta Biomater, 6, 3, 10.1016/j.actbio.2009.07.031 · DOI
  175. Wojtowicz, 2010, Coating of biomaterial scaffolds with the collagen-mimetic peptide GFOGER for bone defect repair., Biomaterials, 31, 2574, 10.1016/j.biomaterials.2009.12.008 · DOI
  176. Xu, 2013, Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances., Adv. Drug Deliv Rev., 65, 121, 10.1016/j.addr.2012.09.041 · DOI
  177. Yameen, 2014, Insight into nanoparticle cellular uptake and intracellular targeting., J. Control Release, 190, 485, 10.1016/j.jconrel.2014.06.038 · DOI
  178. Yao, 2017, Laminin: loss-of-function studies., Cell Mol. Life Sci., 74, 1095, 10.1007/s00018-016-2381-0 · DOI
  179. Yigit, 2011, Fabrication and functionalization of hydrogels through click chemistry., Chem. Asian. J., 6, 2648, 10.1002/asia.201100440 · DOI
  180. Yoneda, 2003, Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans., Matrix Biol., 22, 25, 10.1016/S0945-053X(03)00010-6 · DOI · Paper page
  181. Zeltz, 2014, Molecular composition and function of integrin-based collagen glues-introducing COLINBRIs., Biochim. Biophys. Acta, 1840, 2533, 10.1016/j.bbagen.2013.12.022 · DOI
  182. Zhao, 2015, Chondroitin sulfate-based nanocarriers for drug/gene delivery., Carbohydr. Polym., 133, 391, 10.1016/j.carbpol.2015.07.063 · DOI
  183. Zhong, 2018, A comprehensive map of FDA-approved pharmaceutical products., Pharmaceutics, 10, 10.3390/pharmaceutics10040263 · DOI
  184. Zhou, 2016, Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modified PEG-trimethyl chitosan., Biomater. Sci., 4, 849, 10.1039/c5bm00629e · DOI
  185. Zhou, 2019, Bioactive peptide amphiphile nanofiber gels enhance burn wound healing., Burns, 45, 1112, 10.1016/j.burns.2018.06.008 · DOI
  186. Zieris, 2011, Dual independent delivery of pro-angiogenic growth factors from starPEG-heparin hydrogels., J. Control Release, 156, 28, 10.1016/j.jconrel.2011.06.042 · DOI
  187. Zieris, 2010, FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis., Biomaterials, 31, 7985, 10.1016/j.biomaterials.2010.07.021 · DOI · Paper page
  188. Zilberman, 2008, Antibiotic-eluting medical devices for various applications., J. Control Release, 130, 202, 10.1016/j.jconrel.2008.05.020 · DOI · Paper page
  189. Zollinger, 2017, Fibronectin, the extracellular glue., Matrix Biol., 6, 27, 10.1016/j.matbio.2016.07.011 · DOI
  190. Zustiak, 2010, Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties., Biomacromolecules, 11, 1348, 10.1021/bm100137q · DOI

Cited by

Sorted by citations

See all 76

Metadata

Authors
Hwang, J., Sullivan, M. O., & Kiick, K. L.
Venue
Frontiers in Bioengineering and Biotechnology
Publisher
Frontiers Media SA
Published
2020-02-18
Volume
8
ISSN
2296-4185
DOI
10.3389/fbioe.2020.00069
PMC
PMC7040483
Cited by
76
References
8
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
National Institutes of Health (NIH R01 AR067247, NIH R21 AR069778, NIH P30GM110758)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Targeted Drug Delivery via the Use of ECM-Mimetic Materials. https://app.cochat.ai/papers/10.3389/fbioe.2020.00069
The paper
Hwang, J., Sullivan, M. O., & Kiick, K. L. (2020). Targeted Drug Delivery via the Use of ECM-Mimetic Materials. Frontiers in Bioengineering and Biotechnology. https://doi.org/10.3389/fbioe.2020.00069