Cited by 49Substance Abuse Treatment and OutcomesAlcohol Consumption and Health EffectsNeurotransmitter Receptor Influence on Behavior

Subjective alcohol effects and drinking behavior: The relative influence of early response and acquired tolerance

Morean, Meghan E., Corbin, William R.·2008·Addictive Behaviors

Abstract

Objectives (1) To establish the reliability and validity of a modified version of the Self-Rating of Alcohol (SRE) form. (2) To differentiate early subjective alcohol response (SR) from acquired tolerance in the prediction of drinking outcomes.Method 353 undergraduates completed an online survey. SR was assessed using the SRE form and a modified SRE including items assessing global stimulant and sedative effects. The Daily Drinking Questionnaire-Revised (DDQ-R), and the Rutgers Alcohol Problems Index (RAPI) assessed alcohol use and problems, respectively.Results The revised version of the SRE showed good internal consistency and incremental validity. Early SR assessed by the modified SRE was consistently associated with use and problems. Acquired tolerance was significantly related to use and problems above and beyond early SR.Conclusions The modified SRE incorporating stimulant and sedative responses demonstrated good psychometric properties and the potential to capture unique variability in drinking outcomes. Differentiating early SR from tolerance showed that each contributes uniquely to drinking behavior and problems. Thus, future studies would benefit from examining the unique contribution of each aspect of SR.

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Crossref · 10.1016/j.addbeh.2008.06.007

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  • Tolerance theory implies that attenuation of subjective alcohol responses over time plays a key role in the development of addiction.

    “Tolerance, a diagnostic criteria for AUD from DSM-III (1980) to DSM-5 (2013)(8), implies that attenuation of subjective alcohol responses over time plays a key role in the development of addiction.”
  • Human studies in this area have been limited to retrospective patient reports, post mortem brain tissue methods, or cross-sectional laboratory paradigms, none of which directly measure alcohol responses in the same individuals over time.

    “Human studies in this area have been limited to retrospective patient reports(23), post mortem brain tissue methods(24), or cross-sectional laboratory paradigms(2, 3, 25–29), none of which directly measure alcohol responses in the same individuals over time.”
  • Previous studies relying on proxy measures of brain-behavior relationships to alcohol response have not been able to address within-person changes or stabilization in alcohol response over time.

    “Previous studies relying on proxy measures of brain-behavior relationships to alcohol response(2, 3, 23–29) have not been able to address within-person changes or stabilization in alcohol response over time.”

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Authors
Morean, M. E., & Corbin, W. R.
Affiliations
Yale University (US)
Corresponding author
Morean, Meghan E.
Venue
Addictive Behaviors
Publisher
Elsevier BV
Published
2008-10
Volume
33
Issue
10
Pages
1306-1313
ISSN
0306-4603 (ISSN-L)
OpenAlex
W1984111667
Cited by
49
References
33
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 5 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 4 · 2014: 3 · 2013: 4 · 2012: 3
FWCI
1.48
Type
journal article
Language
en
Open access
closed
Locations
  • Addictive Behaviors (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
psychometric validation, alcohol consumption, alcohol-related problems, drinking behavior, undergraduate students
MeSH terms
Adolescent, Alcohol Drinking, Alcoholism, Factor Analysis, Statistical, Female, Humans, Male, Surveys and Questionnaires, Regression Analysis, Self-Assessment, Students, Reproducibility of Results, Young Adult

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