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The sequence of the human genome

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A multidrug resistance transporter from human MCF-7 breast cancer cells

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

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Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

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The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

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Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

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The superfamily of organic anion transporting polypeptides

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

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Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells

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Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

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Molecular Identification and Characterization of Novel Members of the Human Organic Anion Transporter (OATP) Family

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OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

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MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

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Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney

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Identification and characterization of limbal stem cells

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The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology

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The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

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Characterization of Putative Stem Cell Phenotype in Human Limbal Epithelia

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Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6

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Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta

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Role of the breast cancer resistance protein (ABCG2) in drug transport

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Folate-targeted, Anionic Liposome-entrapped Polylysine-condensed DNA for Tumor Cell-specific Gene Transfer

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Role of membrane transport in metabolism and function of glutathione in mammals

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Pharmacological and Physiological Functions of the Polyspecific Organic Cation Transporters: OCT1, 2, and 3 (SLC22A1-3)

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Function and structure of heterodimeric amino acid transporters

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Cytotoxicity of Antiviral Nucleotides Adefovir and Cidofovir Is Induced by the Expression of Human Renal Organic Anion Transporter 1

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The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1

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Inhibition of Transporter-Mediated Hepatic Uptake as a Mechanism for Drug-Drug Interaction between Cerivastatin and Cyclosporin A

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The structural basis of the blood-ocular barriers

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ABCG2 Transporter Identifies a Population of Clonogenic Human Limbal Epithelial Cells

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Valacyclovir: A Substrate for the Intestinal and Renal Peptide Transporters PEPT1 and PEPT2

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Cyclosporine Interacts with Mycophenolic Acid by Inhibiting the Multidrug Resistance-Associated Protein 2

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Molecular Characterization and Inhibition of Amanitin Uptake into Human Hepatocytes

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System L: heteromeric exchangers of large, neutral amino acids involved in directional transport

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Glutamate receptors and circuits in the vertebrate retina

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Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine

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Targeted prodrug design to optimize drug delivery

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Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Antiviral Transport

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Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters

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Coincidence of L‐glutamate/L‐aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: Evidence for coupling of GLAST and GS in transmitter clearance

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Permeability of Retinal Pigment Epithelium: Effects of Permeant Molecular Weight and Lipophilicity

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ATP‐ and glutathione‐dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1

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MRP8, ATP-binding Cassette C11 (ABCC11), Is a Cyclic Nucleotide Efflux Pump and a Resistance Factor for Fluoropyrimidines 2′,3′-Dideoxycytidine and 9′-(2′-Phosphonylmethoxyethyl)adenine

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The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites

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(Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Mammalian Nucleoside Transporters

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Cyclosporin A Is a Broad-Spectrum Multidrug Resistance Modulator

Qadir, M., O'Loughlin, K. L., Fricke, S. M., Williamson, N. A., Greco, W. R., Minderman, H., & Baer, M. R. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-1725 · Cited by 236

Active Secretion of Drugs from the Small Intestinal Epithelium in Rats by P-Glycoprotein Functioning as an Absorption Barrier

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Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)

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Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells

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The active transport of fluorescein by the retinal vessels and the retina

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Pharmacogenetics/genomics and personalized medicine

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Transporters and Renal Drug Elimination

Lee, W., & Kim, R. B. (2004) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121856 · Cited by 222

Molecular Features, Regulation, and Function of Monocarboxylate Transporters: Implications for Drug Delivery

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Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir

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The blood–retinal barriers system. Basic concepts and clinical evaluation

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The glutamate and neutral amino acid transporter family: physiological and pharmacological implications

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Isolation of a Family of Organic Anion Transporters from Human Liver and Kidney

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Human limbal epithelium contains side population cells expressing the ATP‐binding cassette transporter ABCG2

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Ocular Pharmacokinetics

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Intestinal Transport of β-Lactam Antibiotics: Analysis of the Affinity at the H+/Peptide Symporter (PEPT1), the Uptake into Caco-2 Cell Monolayers and the Transepithelial Flux

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BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION

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Polyspecific organic cation transporters: their functions and interactions with drugs

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The Organic Anion Transporter (OATP) Family

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Interactions of Human Organic Anion Transporters and Human Organic Cation Transporters with Nonsteroidal Anti-Inflammatory Drugs

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Corneal Penetration Behavior of β-Blocking Agents II: Assessment of Barrier Contributions

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Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE

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Lactate transport and transporters: General principles and functional roles in brain cells

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Polarized Expression of Monocarboxylate Transporters in Human Retinal Pigment Epithelium and ARPE-19 Cells

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Functional Characterization and Comparison of the Outer Blood–Retina Barrier and the Blood–Brain Barrier

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Expression and Differential Polarization of the Reduced-folate Transporter-1 and the Folate Receptor α in Mammalian Retinal Pigment Epithelium

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Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver.

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Mechanistic Studies on Transcorneal Permeation of Pilocarpine

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p-Aminohippuric Acid Transport at Renal Apical Membrane Mediated by Human Inorganic Phosphate Transporter NPT1

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Identification of a Unique Monocarboxylate Transporter (MCT3) in Retinal Pigment Epithelium

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Nonsteroidal Anti-Inflammatory Drugs Efficiently Reduce the Transport and Cytotoxicity of Adefovir Mediated by the Human Renal Organic Anion Transporter 1

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Transport of Amino Acid-Based Prodrugs by the Na+- and Cl--Coupled Amino Acid Transporter ATB0,+ and Expression of the Transporter in Tissues Amenable for Drug Delivery

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Breast Cancer Resistance Protein (BCRP/ABCG2) Induces Cellular Resistance to HIV-1 Nucleoside Reverse Transcriptase Inhibitors

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Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells

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Advances in the Cell Biology of Transport via the Inner Blood-Retinal Barrier: Establishment of Cell Lines and Transport Functions

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Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain

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Localization of the glutamate transporter protein GLAST in rat retina

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Ocular surface epithelial and stem cell development

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P-glycoprotein expression in human retinal pigment epithelium.

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A comparison of rhodamine 123 accumulation and efflux in cells with P-glycoprotein-mediated and MRP-associated multidrug resistance phenotypes

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Isolated microvessels: the blood-brain barrier in vitro.

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Membrane transporters

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Molecular Evidence and Functional Expression of P-Glycoprotein (MDR1) in Human and Rabbit Cornea and Corneal Epithelial Cell Lines

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Rat Multispecific Organic Anion Transporter 1 (rOAT1) Transports Zidovudine, Acyclovir, and Other Antiviral Nucleoside Analogs

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Cloning and Functional Characterization of a New Multispecific Organic Anion Transporter, OAT-K2, in Rat Kidney

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