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Cited by 268

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Material properties in complement activation

Open access
Moghimi, S. Moein, Andersen, Alina J., Ahmadvand, Davoud, Wibroe, Peter P., Andresen, Thomas L., Hunter, A. Christy·2011·Advanced Drug Delivery Reviews

Abstract

Uncontrolled complement activation can induce many inflammatory and life threatening conditions. Accordingly, the role of complement in initiation of adverse reactions to polymers and nanoparticulate drug carriers is receiving increasing attention and has prompted extensive 'structure-immune performance' relationship studies in nanomedicine research at many fronts. The interaction between nanomaterials and the complement system is complex and regulated by inter-related factors that include nanoscale size, morphology and surface characteristics. Each of these parameters may affect complement activation differently and through different sensing molecules and initiation pathways. The importance of material properties in triggering complement is considered and mechanistic aspects discussed. Mechanistic understanding of complement events could provide rational approaches for improved material design and nanoengineering strategies for clinical medicine.

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Crossref · 10.1016/j.addr.2011.06.002

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Metadata

Authors
Moghimi, S. M., Andersen, A. J., Ahmadvand, D., Wibroe, P. P., Andresen, T. L., & Hunter, A. C.
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2011-09
Volume
63
Issue
12
Pages
1000-1007
ISSN
0169-409X (ISSN-L)
OpenAlex
W2066793829
Cited by
268
References
73
FWCI
1.31
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Material properties in complement activation. https://app.cochat.ai/papers/10.1016/j.addr.2011.06.002
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Moghimi, S. M., Andersen, A. J., Ahmadvand, D., Wibroe, P. P., Andresen, T. L., & Hunter, A. C. (2011). Material properties in complement activation. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2011.06.002

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.