Cited by 228Pelvic floor disorders treatmentsHernia repair and managementUterine Myomas and Treatments

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Risk factors for mesh/suture erosion following sacral colpopexy

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Cundiff, Geoffrey W., Varner, Edward, Visco, Anthony G., Zyczynski, Halina M., Nager, Charles W., Norton, Peggy A., Schaffer, Joseph, Brown, Morton B., Brubaker, Linda·2008·American Journal of Obstetrics and Gynecology

DOI 10.1016/j.ajog.2008.07.029PMC PMC2859033

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Abstract

Objective The purpose of this study was to identify risks for mesh/suture erosions following abdominal sacral colpopexy (ASC).Study design We analyzed demographic, perioperative variables, and erosion status in 322 participants in the Colpopexy and Urinary Reduction Efforts study 2 years after sacral colpopexy.Results The predominant graft used was synthetic mesh: woven polyester (Mersilene; Ethicon, Inc, Somerville, NJ) (42%) or polypropylene (48%). Twenty subjects (6%) experienced mesh/suture erosion. Unadjusted risk factors for mesh/suture erosion were expanded polytrafluroethylene (ePTFE) mesh (ePTFE 4/21 [19%] vs non-ePTFE 16/301 [5%]; odds ratio [OR], 4.2), concurrent hysterectomy (OR, 4.9), and current smoking (OR, 5.2). Of those with mesh erosion, most affected women (13/17) underwent at least 1 surgery for partial or total mesh removal. Two were completely resolved, 6 had persistent problems, and 5 were lost to follow-up. No resolution was documented in the 4 women who elected observation.Conclusion Expanded PTFE mesh should not be used for sacral colpopexy. Concurrent hysterectomy and smoking are modifiable risks for mesh/suture erosion.

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Authors: Cundiff, G. W., Varner, E., Visco, A. G., Zyczynski, H. M., Nager, C. W., Norton, P. A., Schaffer, J., Brown, M. B., & Brubaker, L.
Affiliations: University of British Columbia (CA)
University of Alabama at Birmingham (US)
University of North Carolina at Chapel Hill (US)
University of Pittsburgh (US)
University of California San Diego (US)
University of Utah (US)
The University of Texas Southwestern Medical Center (US)
University of Michigan (US)
Loyola University Chicago (US)
ORCID: Cundiff, Geoffrey W.
Visco, Anthony G.
Zyczynski, Halina M.
Nager, Charles W.
Brubaker, Linda
Venue: American Journal of Obstetrics and Gynecology
Publisher: Elsevier BV
Published: 2008-12
Volume: 199
Issue: 6
Pages: 688.e1-688.e5
ISSN: 0002-9378 (ISSN-L)
DOI: 10.1016/j.ajog.2008.07.029
PMC: PMC2859033
OpenAlex: W2034559943
Cited by: 228
References: 13
Citations by year: 2026: 5 · 2025: 12 · 2024: 6 · 2023: 5 · 2022: 13 · 2021: 11 · 2020: 18 · 2019: 12 · 2018: 12 · 2017: 16 · 2016: 18 · 2015: 8 · 2014: 19 · 2013: 27 · 2012: 19
FWCI: 6.12
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: American Journal of Obstetrics and Gynecology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (U01DK060380)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10HD041268, U10HD041261, U01HD041249, U10HD041263, U10HD041267, U10HD041248, U10HD041269, U10HD041250, UG1HD041267)
Topics: Health Sciences › Medicine › Urology › Pelvic floor disorders treatments
Health Sciences › Medicine › Surgery › Hernia repair and management
Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
Keywords: sacrocolpopexy, mesh erosion, suture erosion, expanded polytetrafluoroethylene mesh, risk factors, smoking, mesh removal, pelvic organ prolapse surgery
MeSH terms: Adult, Aged, Colposcopy, Female, Follow-Up Studies, Humans, Middle Aged, Prosthesis Design, Prosthesis Failure, Reoperation, Risk Factors, Severity of Illness Index, Gynecologic Surgical Procedures, Surgical Mesh, Sutures, Urinary Incontinence, Stress, Uterine Prolapse

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Risk factors for mesh/suture erosion following sacral colpopexy

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