Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer’s Disease

Serrano-Pozo, Alberto, Mielke, Matthew L., Gómez-Isla, Teresa, Betensky, Rebecca A., Growdon, John H., Frosch, Matthew P., Hyman, Bradley T.·2011·The American Journal of Pathology

Cited by (487)

Items 101–200 of 487

  1. Neurovascular unit dysregulation, white matter disease, and executive dysfunction: the shared triad of vascular cognitive impairment and Alzheimer disease
    Alexander Levit, Vladimir Hachinski, Shawn Narain Whitehead · 2020 · GeroScience
  2. Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles
    Pascual Sánchez‐Juan, Elizabeth Valeriano-Lorenzo, Alicia Ruiz-González, Ana Belén Pastor, Héctor Rodrigo Lara, Francisco López-González, María Ascensión Zea‐Sevilla, Meritxell Valentí, Belén Frades Payo, Paloma Ruiz et al. · 2024 · Brain
  3. Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer’s disease–related mouse models
    Dutta, Debashis, Jana, Malabendu, Paidi, Ramesh Kumar, Majumder, Moumita, Raha, Sumita, Dasarathy, Sridevi, Pahan, Kalipada · 2023 · Journal of Clinical Investigation
  4. Brain injury-induced dysfunction of the blood brain barrier as a risk for dementia
    Eric E. Abrahamson, Miloš D. Ikonomović · 2020 · Experimental Neurology
  5. Sex-specific effects of microglial activation on Alzheimer’s disease proteinopathy in older adults
    Kaitlin Blackstone Casaletto, Emma L. Nichols, Vahan Aslanyan, Stephanie M. Simone, Jennifer S. Rabin, Renaud La Joie, Adam M. Brickman, Kristen Dams-O’Connor, Priya Palta, Raj G. Kumar et al. · 2022 · Brain
  6. The role of astrocytic α7 nicotinic acetylcholine receptors in Alzheimer disease
    Fontana, Igor C., Kumar, Amit, Nordberg, Agneta · 2023 · Nature Reviews Neurology
  7. Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease
    Yara Yakoub, Nicholas James Ashton, Cherie Strikwerda‐Brown, Laia Montoliu‐Gaya, Thomas K. Karikari, Przemysław Radosław Kac, Fernando González‐Ortiz, Jonathan Gallego-Rudolf, Pierre‐François Meyer, Frédéric St‐Onge et al. · 2023 · Alzheimer s & Dementia
  8. Neuropathological assessment of the Alzheimer spectrum
    K. A. Jellinger · 2020 · Journal of Neural Transmission
  9. An Insight into Cellular and Molecular Mechanisms Underlying the Pathogenesis of Neurodegeneration in Alzheimer’s Disease
    Yashumati Ratan, Aishwarya Rajput, Sushmita Maleysm, Aaushi Pareek, Vivek Kumar Jain, Ashutosh Pareek, Ranjeet Kaur, Gurjit Singh · 2023 · Biomedicines
  10. Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer’s disease
    Xingyu Zhang, Li Tang, Jiaolong Yang, Lanxia Meng, Jiehui Chen, Lingyan Zhou, Jiangyu Wang, Min Xiong, Zhentao Zhang · 2023 · Nature Communications
  11. Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease
    Cho, Hanna, Choi, Jae Yong, Lee, Seung Ha, Lee, Jae Hoon, Choi, Young-Chul, Ryu, Young Hoon, Lee, Myoung Sik, Lyoo, Chul Hyoung · 2017 · Neurobiology of Aging
  12. Tau at the interface between neurodegeneration and neuroinflammation
    Didonna, Alessandro · 2020 · Genes & Immunity
  13. <i>APOE</i> ε4 associates with microglial activation independently of Aβ plaques and tau tangles
    Ferrari-Souza, João Pedro, Lussier, Firoza Z., Leffa, Douglas T., Therriault, Joseph, Tissot, Cécile, Bellaver, Bruna, Ferreira, Pâmela C. L., Malpetti, Maura, Wang, Yi-Ting, Povala, Guilherme et al. · 2023 · Science Advances
  14. Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease
    Sonja Rakić, Yat M. A. Hung, Matthew Smith, Denise So, Hannah Mary Tayler, William Varney, Joe Wild, Scott Harris, Clive Holmes, Seth Love et al. · 2018 · Acta Neuropathologica Communications
  15. The roles of microglia and astrocytes in neuroinflammation of Alzheimer’s disease
    Jialin Han, Zhi Zhang, Pengfei Zhang, Qian Yu, Qian Cheng, Zhiming Lu, Shuai Zong · 2025 · Frontiers in Neuroscience
  16. Studying neurodegenerative diseases in culture models
    Johannes C. M. Schlachetzki, Soraya Wilke Saliba, Antônio Carlos Pinheiro de Oliveira · 2013 · Brazilian Journal of Psychiatry
  17. Does neuroinflammation turn on the flame in Alzheimer's disease? Focus on astrocytes
    Luca Steardo, Maria Rosanna Bronzuoli, Aniello Iacomino, Giuseppe Esposito, Luca Steardo, Caterina Scuderi · 2015 · Frontiers in Neuroscience
  18. Essential Oils as a Potential Neuroprotective Remedy for Age-Related Neurodegenerative Diseases: A Review
    Aswir Abd Rashed, Ahmad Zuhairi Abd Rahman, Devi-Nair Gunasegavan Rathi · 2021 · Molecules
  19. What are activated and reactive glia and what is their role in neurodegeneration?
    Bennett, Mariko L., Viaene, Angela N. · 2021 · Neurobiology of Disease
  20. Oxidative stress in Alzheimer's disease: Primary villain or physiological by-product?
    Greg Trevor Sutherland, Belal Chami, Priscilla Youssef, Paul Kenneth Witting · 2013 · Redox Report
  21. CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease
    Jeremy L. Koppel, Valérie Vingtdeux, Philippe Marambaud, Cristina d’Abramo, Heidy T. Jimenez, Mark Stauber, Rachel Friedman, Peter Davies · 2013 · Molecular Medicine
  22. 3H-Deprenyl and 3H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain
    Marutle, Amelia, Gillberg, Per-Göran, Bergfors, Assar, Yu, Wenfeng, Ni, Ruiqing, Nennesmo, Inger, Voytenko, Larysa, Nordberg, Agneta · 2013 · Journal of Neuroinflammation
  23. The endoplasmic reticulum stress and unfolded protein response in Alzheimer's disease: a calcium dyshomeostasis perspective.
    D. Lim, L. Tapella, Giulia Dematteis, A. Genazzani, Marco Corazzari, A. Verkhratsky · 2023 · Ageing Research Reviews
  24. Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease
    Andrew J. Levine, Jeremy A. Miller, Paul Shapshak, Benjamin B. Gelman, Elyse J. Singer, Charles H. Hinkin, Deborah Commins, Susan Morgello, Igor Grant, Steve Horvath · 2013 · BMC Medical Genomics
  25. Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease
    Lara Wahlster, Muriel Arimon, Navine Nasser‐Ghodsi, Kathryn Leigh Post, Alberto Serrano‐Pozo, Kengo Uemura, Oksana Berezovska · 2012 · Acta Neuropathologica
  26. Altered expression of glutamate transporter‐1 and water channel protein aquaporin‐4 in human temporal cortex with Alzheimer's disease
    Akihiko Hoshi, Ayako Tsunoda, Toshiyuki Yamamoto, Mari Tada, Akiyoshi Kakita, Yoshikazu Ugawa · 2018 · Neuropathology and Applied Neurobiology
  27. A state of delirium: Deciphering the effect of inflammation on tau pathology in Alzheimer's disease
    Matthew Barron, Jane E. Gartlon, Lee A. Dawson, Peter J. Atkinson, Marie‐Christine Pardon · 2016 · Experimental Gerontology
  28. Altered microglia and neurovasculature in the Alzheimer's disease cerebellum
    Malvindar K. Singh‐Bains, Vanessa Linke, Micah D. R. Austria, Adelie Y. S. Tan, Emma L. Scotter, Nasim F. Mehrabi, Richard L. M. Faull, Mike Dragunow · 2019 · Neurobiology of Disease
  29. Systematic review of human post‐mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease
    Viejo, Lucía, Noori, Ayush, Merrill, Emily, Das, Sudeshna, Hyman, Bradley T., Serrano‐Pozo, Alberto · 2022 · Neuropathology and Applied Neurobiology
  30. Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias
    Methasit Jaisa-aad, C. Muñoz-Castro, Molly A. Healey, B. Hyman, A. Serrano-Pozo · 2024 · Acta Neuropathologica
  31. Tau-tubulin kinase
    Seiko Ikezu, Tsuneya Ikezu · 2014 · Frontiers in Molecular Neuroscience
  32. Cellular and Molecular Mediators of Neuroinflammation in Alzheimer Disease
    Seung‐Hoon Yang · 2019 · International Neurourology Journal
  33. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: Sensitivity, Specificity and Potential for Clinical Use
    Cristina d’Abramo, Luciano D'adamio, Luca Giliberto · 2020 · Journal of Personalized Medicine
  34. RETRACTED: Biochemical features and therapeutic potential of α-Mangostin: Mechanism of action, medicinal values, and health benefits
    Manzar Alam, Summya Rashid, Kisa Fatima, Mohd Adnan, Alaa Shafie, Salman Akhtar, A.H. Ganie, Sayed M. Eldin, Asimul Islam, Ilyas Khan et al. · 2023 · Biomedicine & Pharmacotherapy · Retracted
  35. Modifiable, Non-Modifiable, and Clinical Factors Associated with Progression of Alzheimer’s Disease
    David A. Loeffler · 2021 · Journal of Alzheimer s Disease
  36. Neuroinflammation PET imaging of the translocator protein (TSPO) in Alzheimer's disease: An update
    Dominique Gouilly, Laure Saint‐Aubert, Maria João Ribeiro, Anne‐Sophie Salabert, Clovis Tauber, Patrice Péran, Nicolas Arlicot, Jérémie Pariente, Pierre Payoux · 2022 · European Journal of Neuroscience
  37. Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?
    Debby Van Dam, Yannick Vermeiren, Alain D. Dekker, Petrus J.W. Naudé, Peter Paul De Deyn · 2016 · Current Alzheimer Research
  38. How the immune system shapes neurodegenerative diseases
    Hannah D. Mason, Dorian B. McGavern · 2022 · Trends in Neurosciences
  39. Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway
    S. Son, Seokjo Kang, Heesun Choi, I. Mook-Jung · 2015 · Molecular Neurodegeneration
  40. Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2
    Erica Staurenghi, Valentina Cerrato, Paola Gamba, Gabriella Testa, Serena Giannelli, Valerio Leoni, Claudio Caccia, Annalisa Buffo, Wendy J. Noble, Beatriz Gomez Perez‐Nievas et al. · 2020 · Redox Biology
  41. Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive decline
    Débora Elisa Peretti, Cecilia Boccalini, Federica Ribaldi, Max Scheffler, Moira Marizzoni, Nicholas James Ashton, Henrik Zetterberg, Kaj Blennow, Giovanni Battista Frisoni, Valentina Garibotto · 2024 · Brain
  42. TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease
    Tournier, Benjamin B., Tsartsalis, Stergios, Rigaud, Daphney, Fossey, Christine, Cailly, Thomas, Fabis, Frédéric, Pham, Tien, Grégoire, Marie-Claude, Kövari, Eniko, Moulin-Sallanon, Marcelle et al. · 2019 · Neurobiology of Disease
  43. Microglial Activation and Connectivity in Alzheimer Disease and Aging
    Rauchmann, Boris‐Stephan, Brendel, Matthias, Franzmeier, Nicolai, Trappmann, Lena, Zaganjori, Mirlind, Ersoezlue, Ersin, Morenas‐Rodriguez, Estrella, Guersel, Selim, Burow, Lena, Kurz, Carolin et al. · 2022 · Annals of Neurology
  44. Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy
    Henika Patel, Pablo Martínez, Abigail Perkins, Xavier Taylor, Nur Jury, David L. McKinzie, Cristian A. Lasagna‐Reeves · 2021 · Neurobiology of Aging
  45. Alzheimer’s Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy
    Tapan K. Khan, Daniel L. Alkon · 2015 · Journal of Alzheimer s Disease
  46. Impact of aging immune system on neurodegeneration and potential immunotherapies
    Zhanfeng Liang, Yang Zhao, Linhui Ruan, Linnan Zhu, Kunlin Jin, Qichuan Zhuge, Dong‐Ming Su, Yong L. Zhao · 2017 · Progress in Neurobiology
  47. The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
    Chandra, Sidhanth, Di Meco, Antonio, Dodiya, Hemraj B., Popovic, Jelena, Cuddy, Leah K., Weigle, Ian Q., Zhang, Xiaoqiong, Sadleir, Katherine, Sisodia, Sangram S., Vassar, Robert · 2023 · Molecular Neurodegeneration
  48. Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer’s disease
    Appleton, Johanna, Finn, Quentin, Zanotti-Fregonara, Paolo, Yu, Meixiang, Faridar, Alireza, Nakawah, Mohammad O, Zarate, Carlos, Carrillo, Maria C, Dickerson, Bradford C, Rabinovici, Gil D et al. · 2025 · Brain
  49. Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies
    Montgomery, Sara L., Narrow, Wade C., Mastrangelo, Michael A., Olschowka, John A., O'Banion, M. Kerry, Bowers, William J. · 2013 · The American Journal of Pathology
  50. Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer’s Disease
    Melania González-Rodríguez, Sandra Villar‐Conde, Veronica Astillero‐Lopez, Patricia Villanueva‐Anguita, Isabel Úbeda‐Bañón, Alicia Flores‐Cuadrado, Alino Martı́nez-Marcos, Daniel Saiz‐Sánchez · 2021 · International Journal of Molecular Sciences
  51. The Biology of Glial Cells and Their Complex Roles in Alzheimer’s Disease: New Opportunities in Therapy
    S. Nirzhor, R. Khan, S. Neelotpol · 2018 · Biomolecules
  52. Reactive and Senescent Astroglial Phenotypes as Hallmarks of Brain Pathologies
    Andrijana Lazic, Vanda Balint, Danijela Stanisavljević Ninković, Mina Perić, Milena J. Stevanović · 2022 · International Journal of Molecular Sciences
  53. Stable Size Distribution of Amyloid Plaques Over the Course of Alzheimer Disease
    Alberto Serrano‐Pozo, Matthew L. Mielke, Alona Muzitansky, Teresa Gómez‐Isla, John H. Growdon, Brian J. Bacskai, Rebecca A. Betensky, Matthew P. Frosch, Bradley T. Hyman · 2012 · Journal of Neuropathology & Experimental Neurology
  54. Complement cascade functions during brain development and neurodegeneration
    Oluwaseun Fatoba, Takahide Itokazu, Toshihide Yamashita · 2021 · FEBS Journal
  55. Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer’s disease
    Daniel T. Ohm, Angela J. Fought, Adam Martersteck, Christina Coventry, Jaiashre Sridhar, Tamar D. Gefen, Sandra Weıntraub, Eileen H. Bigio, Marsel M. Mesulam, Emily Joy Rogalski et al. · 2020 · Brain Pathology
  56. Synaptic Loss, ER Stress and Neuro-Inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer’s Disease
    Heather M. Buchanan, Murray Mackay, K PALMER, Karolína Tothová, Miroslava Katsur, Bettina Platt, David J. Koss · 2020 · Molecular Neurobiology
  57. Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties
    Aisha Siddiqui, Zahoor Shah, Rao Nargis Jahan, Iekhsan Othman, Yatinesh Kumari · 2021 · Biomedicine & Pharmacotherapy
  58. Alpha-mangostin attenuates brain inflammation induced by peripheral lipopolysaccharide administration in C57BL/6J mice
    Miryam Nava Catorce, Gonzalo Acero, José Pedraza‐Chaverrí, Gladis Fragoso, Tzipe Govezensky, Goar Gevorkian · 2016 · Journal of Neuroimmunology
  59. Blood-Based Biomarkers of Neuroinflammation in Alzheimer’s Disease: A Central Role for Periphery?
    Federica Angiulli, Elisa Conti, C Zoia, Fulvio Da Re, Ildebrando Marco Appollonio, Carlo Ferrarese, Lucio Tremolizzo · 2021 · Diagnostics
  60. A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment
    Mathur, Ryan, Ince, Paul G., Minett, Thais, Garwood, Claire J., Shaw, Pamela J., Matthews, Fiona E., Brayne, Carol, Simpson, Julie E., Wharton, Stephen B., on behalf of the MRC Cognitive Function and Ageing Neuropathology Study Group · 2015 · PLOS ONE
  61. RETRACTED: Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice
    Wei Zhang, Miao Bai, Xi Ye, Jian Hao, Zhuo Zhang, Changjun Su, Gesheng Lei, Jianting Miao, Zhuyi Li · 2012 · Neurobiology of Aging · Retracted
  62. Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation
    Fan, Min, Liu, Sen, Sun, Hui-Min, Ma, Meng-Die, Gao, Ye-Jun, Qi, Cong-Cong, Xia, Qing-Rong, Ge, Jin-Fang · 2022 · Biomedicine &amp; Pharmacotherapy
  63. Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model
    Samantha M. Rossano, Aubrey S. Johnson, Anna P. Smith, Galen Ziaggi, Andrew E. Roetman, Diana Guzman, Amarachukwu Okafor, Julia Klein, Zeljko Tomljanovic, Yaakov Stern et al. · 2024 · Alzheimer s & Dementia
  64. Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins
    Jean Paul Chadarevian, Hayk Davtyan, Alina L Chadarevian, Jasmine Nguyen, Joia Kai Capocchi, Lauren Le, Adrian Escobar, Talar Chadarevian, Khaled Mansour, Ekaterina Deynega et al. · 2025 · Cell stem cell
  65. Ketamine Inhibits Lipopolysaccharide-Induced Astrocytes Activation by Suppressing TLR4/NF-?B Pathway
    Yuqing Wu, Wei Li, Ce Zhou, Fuzhao Lu, Tianhui Gao, Yingchun Liu, Junli Cao, Yong-Mei Zhang, Yongqing Zhang, Chenghua Zhou · 2012 · Cellular Physiology and Biochemistry
  66. Activated Microglia in Cortical White Matter Across Cognitive Aging Trajectories
    Tamar D. Gefen, Garam Kım, Kabriya Bolbolan, Andrew D. Geoly, Daniel T. Ohm, Carly Oboudiyat, Ryan K. Shahidehpour, ALFRED W. RADEMAKER, Sandra Weıntraub, Eileen H. Bigio et al. · 2019 · Frontiers in Aging Neuroscience
  67. The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease
    Sarah Gourmaud, David A. Stewart, David John Irwin, Nicholas Roberts, Aaron J Barbour, Grace Eberwine, William T. O’Brien, Robert J. Vassar, Delia M. Talos, Frances E. Jensen · 2021 · Brain
  68. Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer’s disease
    Serrano-Pozo, Alberto, Li, Zhaozhi, Noori, Ayush, Nguyen, Huong N., Mezlini, Aziz, Li, Liang, Hudry, Eloise, Jackson, Rosemary J., Hyman, Bradley T., Das, Sudeshna · 2021 · Nature Aging
  69. The Role of Amyloid-Beta and Tau in the Early Pathogenesis of Alzheimer’s Disease
    Yin, Xiaomin, Qiu, Yanyan, Zhao, Chenhao, Zhou, Zheng, Bao, Junze, Qian, Wei · 2021 · Medical Science Monitor
  70. Regional and Gender Study of Neuronal Density in Brain during Aging and in Alzheimer's Disease
    Eva Martínez‐Pinilla, Cristina Ordóñez, Eva del Valle, Ana Navarro, Jorge Tolivia · 2016 · Frontiers in Aging Neuroscience
  71. Mulberry Fruit Extract Alleviates Cognitive Impairment by Promoting the Clearance of Amyloid-β and Inhibiting Neuroinflammation in Alzheimer’s Disease Mice
    Dianxun Liu, Dongqing Du · 2020 · Neurochemical Research
  72. Calcium dysregulation in relation to <scp>A</scp>lzheimer‐type pathology in the ageing brain
    Garwood, C., Faizullabhoy, A., Wharton, S. B., Ince, P. G., Heath, P. R., Shaw, P. J., Baxter, L., Gelsthorpe, C., Forster, G., Matthews, F. E. et al. · 2013 · Neuropathology and Applied Neurobiology
  73. Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice
    Christa Løth Myhre, Camilla Thygesen, Birgitte Villadsen, Jeanette Vollerup, Laura Ilkjær, Katrine Tækker Krohn, Manuela Grebing, Shuainan Zhao, Asif Manzoor Khan, Lasse Dissing‐Olesen et al. · 2019 · Frontiers in Cellular Neuroscience
  74. PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Disease
    Nabil Itzi Luna‐Viramontes, B. Berenice Campa-Córdoba, Miguel Ángel Ontiveros‐Torres, Charles R. Harrington, Ignacio Villanueva‐Fierro, Parménides Guadarrama-Ortíz, Linda Garcés‐Ramírez, Fidel de la Cruz, Mario Hernándes‐Alejandro, Sandra Martínez-Robles et al. · 2020 · Frontiers in Cellular Neuroscience
  75. Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection
    Yang, Fangjia, Beltran-Lobo, Paula, Sung, Katherine, Goldrick, Caoimhe, Croft, Cara L., Nishimura, Agnes, Hedges, Erin, Mahiddine, Farah, Troakes, Claire, Golde, Todd E. et al. · 2024 · Science Advances
  76. Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and <i>APOE</i> in Alzheimer's disease
    Das, Sudeshna, Li, Zhaozhi, Wachter, Astrid, Alla, Srinija, Noori, Ayush, Abdourahman, Aicha, Tamm, Joseph A., Woodbury, Maya E., Talanian, Robert V., Biber, Knut et al. · 2024 · Alzheimer's &amp; Dementia
  77. NAD+-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer’s disease via ATF4-dependent mitochondrial UPR
    Xi Xiong, Jia-Long Hou, Yi Zheng, Tao Jiang, Xue-Miao Zhao, Jin-Lai Cai, Jia-Ni Huang, Hai-Jun He, Jia-Xue Xu, Shuang-Jie Qian et al. · 2024 · Cell Death and Disease
  78. Neuronal and Glial Distribution of Tau Protein in the Adult Rat and Monkey
    Kanaan, Nicholas M., Grabinski, Tessa · 2021 · Frontiers in Molecular Neuroscience
  79. Aberrant Wnt signaling: a special focus in CNS diseases
    Mercedes Arnés, Sergio Casas‐Tintó · 2017 · Journal of Neurogenetics
  80. Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease
    Christopher Bi, Stephanie Bi, Bin Li · 2018 · Aging and Disease
  81. Cholesterol Dysmetabolism in Alzheimer’s Disease: A Starring Role for Astrocytes?
    Staurenghi, Erica, Giannelli, Serena, Testa, Gabriella, Sottero, Barbara, Leonarduzzi, Gabriella, Gamba, Paola · 2021 · Antioxidants
  82. Highlighting Immune System and Stress in Major Depressive Disorder, Parkinson’s, and Alzheimer’s Diseases, with a Connection with Serotonin
    Ana Salomé Correia, Armando Cardoso, Nuno Vale · 2021 · International Journal of Molecular Sciences
  83. Neuropathology of the Alzheimer's continuum: an update
    K. A. Jellinger · 2020 · Free Neuropathology
  84. Fungicide Residues Exposure and β-amyloid Aggregation in a Mouse Model of Alzheimer’s Disease
    Pierre‐André Lafon, Yunyun Wang, Margarita Arango-Lievano, Joan Torrent, Lucie Salvador-Prince, Marine Mansuy, Nadine Mestre‐Francés, Laurent Givalois, Jianfeng Liu, Josep Vicent Mercader et al. · 2020 · Environmental Health Perspectives
  85. Neuroinflammation in Alzheimer's disease and beneficial action of luteolin
    Alejandro Delgado, Christos Cholevas, Theoharis Constantin Theoharides · 2021 · BioFactors
  86. Artificial Intelligence Models in the Diagnosis of Adult-Onset Dementia Disorders: A Review
    Gopi Battineni, Nalini Chintalapudi, Mohammad Amran Hossain, Giuseppe Losco, Ciro Ruocco, Getu Gamo Sagaro, Enea Traini, Giulio Nittari, Francesco Amenta · 2022 · Bioengineering
  87. Microglial Depletion, a New Tool in Neuroinflammatory Disorders: Comparison of Pharmacological Inhibitors of the CSF ‐ 1R
    David Guenoun, Nathan Blaise, Alexandre Sellam, Julie Roupret‐Serzec, Alice Jacquens, Juliette Van Steenwinckel, Pierre Gressèns, Cindy Bokobza · 2024 · Glia
  88. Amyloid‐ A β Peptide in Olfactory Mucosa and Mesenchymal Stromal Cells of Mild Cognitive Impairment and A lzheimer's Disease Patients
    Carlos A. Ayala‐Grosso, Rosalinda Pieruzzini, Dylana Diaz‐Solano, Olga Wittig, Ligia Abrante, Leslie Vargas‐Saturno, José E. Cardier · 2014 · Brain Pathology
  89. Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice
    Eun-Jeong Yang, Usman Mahmood, Hyun-Ju Kim, Moonseok Choi, Yunjung Choi, Jean‐Pyo Lee, Joo‐Youn Cho, Jin Won Hyun, Yong Sik Kim, Moon‐Jeong Chang et al. · 2018 · Free Radical Biology and Medicine
  90. Gut microbiota mediated allostasis prevents stress-induced neuroinflammatory risk factors of Alzheimer's disease
    Susan Westfall, Umar Haris Iqbal, Maria Sebastian-Valverde, Giulio Maria Pasinetti · 2019 · Progress in molecular biology and translational science
  91. Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer’s Disease Patients
    Athanasios Metaxas, Camilla Thygesen, Sanne R. R. Briting, Anne Marlene Landau, Sultan Darvesh, Bente R. Finsen · 2019 · Frontiers in Cellular Neuroscience
  92. Acute phase markers in CSF reveal inflammatory changes in Alzheimer’s disease that intersect with pathology, APOE ε4, sex and age
    Scott Ayton, Shorena Janelidze, Blaine Russell Roberts, Sebastian Palmqvist, Pawel Kalinowski, Ibrahima Diouf, Abdel Ali Belaidi, Erik Stomrud, Ashley Ian Bush, Oskar Hansson · 2020 · Progress in Neurobiology
  93. Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease
    Muñoz-Castro, Clara, Noori, Ayush, Magdamo, Colin G., Li, Zhaozhi, Marks, Jordan D., Frosch, Matthew P., Das, Sudeshna, Hyman, Bradley T., Serrano-Pozo, Alberto · 2022 · Journal of Neuroinflammation
  94. Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies
    Finze, Anika, Biechele, Gloria, Rauchmann, Boris-Stephan, Franzmeier, Nicolai, Palleis, Carla, Katzdobler, Sabrina, Weidinger, Endy, Guersel, Selim, Schuster, Sebastian, Harris, Stefanie et al. · 2023 · Molecular Psychiatry
  95. Type-I Interferons in Alzheimer's Disease and Other Tauopathies
    Sophie Sanford, William A. McEwan · 2022 · Frontiers in Cellular Neuroscience
  96. Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes
    Steffi De Meyer, Elena Raluca Blujdea, Jolien M. Schaeverbeke, Mariska Reinartz, Emma Susanne Luckett, Katarzyna Adamczuk, Koen Van Laere, Patrick J. Dupont, Charlotte Elisabeth Teunissen, Rik R. Vandenberghe et al. · 2023 · Brain
  97. Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
    Emre Fertan, Jeff Y. L. Lam, Giulia Albertini, Maarten Dewilde, Yunzhao Wu, Oluwatomi E. S. Akingbade, Dorothea Böken, Elizabeth A. English, Bart De Strooper, David Klenerman · 2025 · Alzheimer s & Dementia
  98. Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry
    Francesca Palombo, Francesco Tamagnini, J. Charles G. Jeynes, Sara Mattana, Imogen J. Swift, Jayakrupakar Nallala, Jane M. Hancock, Jon T. Brown, Andrew D. Randall, Nicholas Stone · 2017 · The Analyst
  99. Blood-brain barrier and innate immunity in the pathogenesis of Alzheimer's disease
    Goran Šimić, Ena Španić, Lea Langer Horvat, Patrick R. Hof · 2019 · Progress in molecular biology and translational science
  100. The role of microbial infection in the pathogenesis of Alzheimer’s disease and the opportunity for protection by anti-microbial peptides
    Feijie Li, Milton T. W. Hearn, Louise E. Bennett · 2021 · Critical Reviews in Microbiology