The DOI matches its Crossref record; 72 of the 73 references it cites were found in a registry or an index.
Effects of Plant-Based Diets on Plasma Lipids
Abstract
Dyslipidemia is a primary risk factor for cardiovascular disease, peripheral vascular disease, and stroke. Current guidelines recommend diet as first-line therapy for patients with elevated plasma cholesterol concentrations. However, what constitutes an optimal dietary regimen remains a matter of controversy. Large prospective trials have demonstrated that populations following plant-based diets, particularly vegetarian and vegan diets, are at lower risk for ischemic heart disease mortality. The investigators therefore reviewed the published scientific research to determine the effectiveness of plant-based diets in modifying plasma lipid concentrations. Twenty-seven randomized controlled and observational trials were included. Of the 4 types of plant-based diets considered, interventions testing a combination diet (a vegetarian or vegan diet combined with nuts, soy, and/or fiber) demonstrated the greatest effects (up to 35% plasma low-density lipoprotein cholesterol reduction), followed by vegan and ovolactovegetarian diets. Interventions allowing small amounts of lean meat demonstrated less dramatic reductions in total cholesterol and low-density lipoprotein levels. In conclusion, plant-based dietary interventions are effective in lowering plasma cholesterol concentrations.
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“Additionally, randomized controlled trial evidence showing the protective effect of plant-based diets on intermediate outcomes, including weight change, lipid profile, glycemic control, and blood pressure lends further support to our findings.(35–38)”
From Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults (2017) · cites this paper as [36]
Citations
Cites
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Cited by
Sorted by citations
Satija, A., Bhupathiraju, S. N., Rimm, E. B., Spiegelman, D., Chiuve, S. E., Borgi, L., Willett, W. C., Manson, J. E., Sun, Q., & Hu, F. B. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002039 · Cited by 1,069
Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults
Satija, A., Bhupathiraju, S. N., Spiegelman, D., Chiuve, S. E., Manson, J. E., Willett, W., Rexrode, K. M., Rimm, E. B., & Hu, F. B. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.05.047 · Cited by 991
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Vitamin B12 among Vegetarians: Status, Assessment and Supplementation
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Metadata
- Authors
- Ferdowsian, H. R., & Barnard, N. D.
- Affiliations
- George Washington University (US)
- Corresponding author
- Ferdowsian, Hope R.
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2009-10
- Volume
- 104
- Issue
- 7
- Pages
- 947-956
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W1976331330
- Cited by
- 196
- References
- 73
- Citations by year
- 2025: 9 · 2024: 8 · 2023: 10 · 2022: 6 · 2021: 20 · 2020: 20 · 2019: 11 · 2018: 8 · 2017: 17 · 2016: 9 · 2015: 13 · 2014: 15 · 2013: 12 · 2012: 14
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Physical Sciences › Environmental Science › Ecology › Agriculture Sustainability and Environmental Impact
- Keywords
- plant-based diet, plasma lipids, dyslipidemia, LDL cholesterol, total cholesterol, vegetarian diet, vegan diet, dietary intervention, cardiovascular risk, nuts, soybean, dietary fiber
- MeSH terms
- Cardiovascular Diseases, Coronary Artery Disease, Female, Humans, Hyperlipidemias, Cholesterol, LDL, Male, Phytotherapy, Plants, Prognosis, Diet, Vegetarian, Randomized Controlled Trials as Topic, Treatment Outcome, Risk Assessment, Dietary Supplements
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