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Cited by 257Nutritional Studies and DietLipoproteins and Cardiovascular HealthAgriculture Sustainability and Environmental Impact

The Role of Specific Components of a Plant-Based Diet in Management of Dyslipidemia and the Impact on Cardiovascular Risk

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Trautwein, Elke A., McKay, Sue·2020·Nutrients
DOI 10.3390/nu12092671PMC PMC7551487
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Abstract

Convincing evidence supports the intake of specific food components, food groups, or whole dietary patterns to positively influence dyslipidemia and to lower risk of cardiovascular diseases (CVD). Specific macro- and micro-components of a predominantly plant-based dietary pattern are vegetable fats, dietary fibers, and phytonutrients such as phytosterols. This review summarizes the current knowledge regarding effects of these components on lowering blood lipids, i.e., low-density lipoprotein cholesterol (LDL-C) and on reducing CVD risk. The beneficial role of a plant-based diet on cardiovascular (CV) health has increasingly been recognized. Plant-based dietary patterns include a Mediterranean and Nordic diet pattern, the dietary approaches to stop hypertension (DASH), and Portfolio diet, as well as vegetarian- or vegan-type diet patterns. These diets have all been found to lower CVD-related risk factors like blood LDL-C, and observational study evidence supports their role in lowering CVD risk. These diet patterns are not only beneficial for dyslipidemia management and prevention of CVD but further contribute to reducing the impact of food choices on environmental degradation. Hence, the CV health benefits of a predominantly plant-based diet as a healthy and environmentally sustainable eating pattern are today recommended by many food-based dietary as well as clinical practice guidelines.

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  • Legume seeds, such as chickpeas, are a rich source of resistant starch and have a low glycemic index.

    “Legume seeds, such as chickpeas, are a rich source of resistant starch (RS) and have a low glycemic index (GI).”

    From The Effect of Cooking and Cooling Chickpea Pasta on Resistant Starch Content, Glycemic Response, and Glycemic Index in Healthy Adults (2024) · cites this paper as [7]

    Section 3.1 (page unavailable) identifies legumes as a source of soluble dietary fiber, but does not identify chickpeas as rich in resistant starch or describe their glycemic index. Searches for “resistant starch,” “glycemic index,” and “chickpeas” found no passage addressing those claims. (LLM, conf=0.76)

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  1. [2]Mach F. Baigent C. Catapano A.L. Koskinas K.C. Casula M. Badimon L. Chapman M.J. De Backer G.G. Delgado V. Ference B.A. ESC Scientific Document Group. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk Eur. Heart J. 2020 41 111 188 10.1093/eurheartj/ehz455 31504418 · DOI · Paper page
  2. [3]Ference B.A. Ginsberg H.N. Graham I. Ray K.K. Packard C.J. Bruckert E. Hegele R.A. Krauss R.M. Raal F.J. Schunkert H. Low density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel Eur. Heart J. 2017 38 2459 2472 10.1093/eurheartj/ehx144 28444290 PMC5837225 · DOI · Paper page
  3. [5]Hu F.B. Willet W. C Optimal diets for prevention of coronary heart disease JAMA 2002 288 2569 2578 10.1001/jama.288.20.2569 12444864 · DOI · Paper page
  4. [6]Dalen J.-E. Devries S. Diets to Prevent Coronary Heart Disease 1957–2013: What Have We Learned? Am. J. Med. 2014 127 364 369 10.1016/j.amjmed.2013.12.014 24384466 · DOI · Paper page
  5. [7]Yu E. Malik V.S. Hu F.B. Cardiovascular Disease Prevention by Diet Modification. JACC Health Promotion Series J. Am. Coll. Cardiol. 2018 72 914 926 10.1016/j.jacc.2018.02.085 30115231 PMC6100800 · DOI
  6. [9]Bechthold A. Boeing H. Tetens I. Schwingshackl L. Nothlings U. Perspective: Food-based dietary guidelines in Europe. Scientific concepts, current status, and perspectives Adv. Nutr. 2018 9 544 560 10.1093/advances/nmy033 30107475 PMC6140433 · DOI
  7. [10]Clark M.A. Springmann M. Hill J. Tilman D. Multiple health and environmental impacts of foods PNAS 2019 116 23357 23362 10.1073/pnas.1906908116 31659030 PMC6859310 · DOI
  8. [11]Eilander A. Harika R.K. Zock P.L. Intake and sources of dietary fatty acids in Europe: Are current population intakes of fats aligned with dietary recommendations? Eur. J. Lipid Sci. Technol 2015 117 1370 1377 10.1002/ejlt.201400513 26877707 PMC4736684 · DOI
  9. [12]Mensink R.P. Katan M.B. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects N. Engl. J. Med. 1990 323 439 445 10.1056/NEJM199008163230703 2374566 · DOI
  10. [13]Zock P.L. Blom W.A.M. Nettleton J.A. Hornstra G. Progressing Insights into the Role of Dietary Fats in the Prevention of Cardiovascular Disease Curr. Cardiol. Rep. 2016 18 111 10.1007/s11886-016-0793-y 27650783 PMC5030225 · DOI
  11. [14]Harika R.K. Eilander A. Alssema M. Osendarp S.J. Zock P.L. Intake of fatty acids in general populations worldwide does not meet dietary recommendations to prevent coronary heart disease: A systematic review of data from 40 countries Ann. Nutr. Metab. 2013 63 229 238 10.1159/000355437 24192557 · DOI
  12. [15]Mensink R.P. Effects of Saturated Fatty Acids on Serum Lipids and Lipoproteins: A Systematic Review and Regression Analysis World Health Organization Geneva, Switzerland 2016
  13. [16]Schwingshackl L. Bogensberger B. Benčič A. Knüppel S. Boeing H. Hoffmann G. Effects of oils and solid fats on blood lipids: A systematic review and network meta-analysis J. Lipid Res. 2018 59 1771 1782 10.1194/jlr.P085522 30006369 PMC6121943 · DOI
  14. [18]Zong G. Li Y. Sampson L. Dougherty L.W. Willett W.C. Wanders A.J. Alssema M. Zock P.L. Hu F.B. Sun Q. Monounsaturated fats from plant and animal sources in relation to risk of coronary heart disease among US men and women Am. J. Clin. Nutr. 2018 107 445 453 10.1093/ajcn/nqx004 29566185 PMC5875103 · DOI
  15. [19]Guasch-Ferré M. Liu G. Li Y. Sampson L. Manson J.E. Salas-Salvadó J. Martínez-González M.A. Stampfer M.J. Willett W.C. Sun Q. Olive Oil Consumption and Cardiovascular Risk in U.S Adults. J. Am. Coll. Cardiol. 2020 75 S0735 S1097 10.1016/j.jacc.2020.02.036 PMC7233327 32147453 · DOI
  16. [21]Innes J.K. Calder P.C. Marine Omega-3 (N-3) Fatty Acids for Cardiovascular Health: An Update for 2020 Int. J. Mol. Sci. 2020 21 1362 10.3390/ijms21041362 PMC7072971 32085487 · DOI
  17. [22]Li Y. Hruby A. Bernstein A.M. Ley S.H. Wang D.D. Chiuve S.E. Sampson L. Rexrode K.M. Rimm E.B. Willett W.C. Saturated fats compared with unsaturated fats and sources of carbohydrates in relation to risk of coronary heart disease: A Prospective Cohort Study J. Am. Coll. Cardiol. 2015 66 1538 1548 10.1016/j.jacc.2015.07.055 26429077 PMC4593072 · DOI · Paper page
  18. [23]Neelakantan N. Seah J.Y.H. van Dam R.M. The Effect of Coconut Oil Consumption on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Clinical Trials Circulation 2020 141 803 814 10.1161/CIRCULATIONAHA.119.043052 31928080 · DOI
  19. [24]Eyres L. Eyres M.F. Chisholm A. Brown R.C. Coconut oil consumption and cardiovascular risk factors in humans Nutr. Rev. 2016 74 267 280 10.1093/nutrit/nuw002 26946252 PMC4892314 · DOI · Paper page
  20. [26]Vannice G. Rasmussen H. Position of the academy of nutrition and dietetics: Dietary fatty acids for healthy adults J. Acad. Nutr. Diet. 2014 114 136 153 10.1016/j.jand.2013.11.001 24342605 · DOI
  21. [28]Sacks F.M. Lichtenstein A.H. Wu J.H.Y. Appel L.J. Creager M.A. Kris-Etherton P.M. Miller M. Rimm E.B. Rudel L.L. Robinson J.G. Dietary Fats and Cardiovascular Disease. A Presidential Advisory from the American Heart Association Circulation 2017 136 e1 e23 10.1161/CIR.0000000000000510 28620111 · DOI · Paper page
  22. [29]Mozaffarian D. Aro A. Willett W.C. Health effects of trans-fatty acids: Experimental and observational evidence Eur. J. Clin. Nutr. 2009 63 S5 S21 10.1038/sj.ejcn.1602973 19424218 · DOI · Paper page
  23. [30]Rimm E.B. Appel L.J. Chiuve S.E. Djoussé L. Engler M.B. Kris-Etherton P.M. Mozaffarian D. Siscovick D.S. Lichtenstein A.H. American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Epidemiology and Prevention; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology. Seafood Long-Chain n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: A Science Advisory from the American Heart Association Circulation 2018 138 e35 e47 29773586 PMC6903778
  24. [31]Evans C.E.L. Dietary fibre and cardiovascular health: A review of current evidence and policy Proc. Nutr. Soc. 2020 79 61 67 10.1017/S0029665119000673 31266545 · DOI
  25. [32]Anderson J.W. Baird P. Davis R.H.J. Ferreri S. Knudtson M. Koraym A. Waters V. Williams C.L. Health benefits of dietary fiber Nutr. Rev. 2009 67 188 205 10.1111/j.1753-4887.2009.00189.x 19335713 · DOI · Paper page
  26. [34]Stephen A.M. Champ M.M. Cloran S.J. Fleith M. van Lieshout L. Mejborn H. Burley V.J. Dietary fibre in Europe: Current state of knowledge on definitions, sources, recommendations, intakes and relationships to health Nutr. Res. Rev. 2017 30 149 190 10.1017/S095442241700004X 28676135 · DOI · Paper page
  27. [35]Brown L. Rosner B. Willett W.C. Sacks F.M. Cholesterol-lowering effects of dietary fiber: A meta-analysis Am. J. Clin. Nutr. 1999 69 30 42 10.1093/ajcn/69.1.30 9925120 · DOI · Paper page
  28. [36]Harley L. May M.D. Loveman E. Colquitt J.L. Rees K. Dietary fibre for the primary prevention of cardiovascular disease Cochrane Database Syst. Rev. 2016 7 CD011472 PMC7032538 26758499
  29. [37]Ho H.V. Sievenpiper J.L. Zurbau A. Blanco Mejia S. Jovanovski E. Au-Yeung F. Jenkins A.L. Vuksan V. The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: A systematic review and meta-analysis of randomised-controlled trials Br. J. Nutr. 2016 116 1369 1382 10.1017/S000711451600341X 27724985 · DOI
  30. [38]Whitehead A. Beck E.J. Tosh S. Wolever T.M. Cholesterol lowering effects of oat beta-glucan: A meta-analysis of randomized controlled trials Am. J. Clin. Nutr 2014 100 1413 1421 10.3945/ajcn.114.086108 25411276 PMC5394769 · DOI
  31. [39]Ho H.V. Sievenpiper J.L. Zurbau A. Blanco Mejia S. Jovanovski E. Au-Yeung F. Jenkins A.L. Vuksan V. A systematic review and meta-analysis of randomized controlled trials of the effect of barley β-glucan on LDL-C, non-HDL-C and apoB for cardiovascular disease risk reduction Eur. J. Clin. Nutr. 2016 70 1239 1245 Erratum in Eur J. Clin. Nutr. 2016, 70(11), 1340 27273067
  32. [41]Jovanovski E. Yashpal S. Komishon A. Zurbau A. Blanco Mejia S. Ho H.V.T. Li D. Sievenpiper J. Duvnjak L. Vuksan V. Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: A systematic review and meta-analysis of randomized controlled trials Am. J. Clin. Nutr. 2018 108 922 932 10.1093/ajcn/nqy115 30239559 · DOI
  33. [42]Ho H.V.T. Jovanovski E. Zurbau A. Blanco Mejia S. Sievenpiper J.L. Au-Yeung F. Jenkins A.L. Duvnjak L. Leiter L. Vuksan V. A systematic review and meta-analysis of randomized controlled trials of the effect of konjac glucomannan, a viscous soluble fiber, on LDL cholesterol and the new lipid targets non-HDL cholesterol and apolipoprotein B Am. J. Clin. Nutr. 2017 105 1239 1247 10.3945/ajcn.116.142158 28356275 · DOI
  34. [43]Theuwissen E. Mensink R.P. Water-soluble dietary fibers and cardiovascular disease Physiol. Behav. 2008 94 285 292 10.1016/j.physbeh.2008.01.001 18302966 · DOI · Paper page
  35. [45]Threapleton D.E. Greenwood D.C. Evans C.E. Cleghorn C.L. Nykjaer C. Woodhead C. Cade J.E. Gale C.P. Burley V.J. Dietary fibre intake and risk of cardiovascular disease: Systematic review and meta-analysis BMJ 2013 347 f6879 10.1136/bmj.f6879 24355537 PMC3898422 · DOI · Paper page
  36. [46]Partula V. Deschasaux M. Druesne-Pecollo N. Latino-Martel P. Desmetz E. Chazelas E. Kesse-Guyot E. Julia C. Fezeu L.K. Galan P. Associations between consumption of dietary fibers and the risk of cardiovascular diseases, cancers, type 2 diabetes, and mortality in the prospective NutriNet-Santé cohort Am. J. Clin. Nutr. 2020 112 195 207 10.1093/ajcn/nqaa063 32369545 · DOI · Paper page
  37. [47]Trautwein E.A. Vermeer M.A. Hiemstra H. Ras R.T. LDL-cholesterol lowering of plant sterols and stanols-which factors influence their efficacy? Nutrients 2018 10 1262 10.3390/nu10091262 30205492 PMC6163911 · DOI
  38. [48]Ras R.T. van der Schouw Y.T. Trautwein E.A. Sioen I. Dalmeijer G.W. Zock P.L. Beulens J.W. Intake of phytosterols from natural sources and risk of cardiovascular disease in the European prospective investigation into cancer and nutrition-the Netherlands (epic-nl) population Eur. J. Prev. Cardiol. 2015 22 1067 1075 10.1177/2047487314554864 25305273 · DOI
  39. [49]Jaceldo-Siegl K. Lutjohann D. Sirirat R. Mashchak A. Fraser G.E. Haddad E. Variations in dietary intake and plasma concentration of plant sterols across plant-based diets among north American adults Mol. Nutr. Food Res. 2017 61 10.1002/mnfr.201600828 PMC5533645 28130879 · DOI
  40. [50]Appel L.J. Moore T.J. Obarzanek E. Vollmer W.M. Svetkey L.P. Sacks F.M. Bray G.A. Vogt T.M. Cutler J.A. Windhauser M.M. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group N. Engl. J. Med. 1997 336 1117 1124 10.1056/NEJM199704173361601 9099655 · DOI · Paper page
  41. [51]Jenkins D.J. Kendall C.W. Marchie A. Faulkner D.A. Wong J.M. de Souza R. Emam A. Parker T.L. Vidgen E. Trautwein E.A. Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants Am. J. Clin. Nutr. 2005 81 380 387 10.1093/ajcn.81.2.380 15699225 · DOI
  42. [52]Pollak O.J. Reduction of blood cholesterol in man Circulation 1953 7 702 706 10.1161/01.CIR.7.5.702 13042924 · DOI
  43. [53]Katan M.B. Grundy S.M. Jones P. Law M. Miettinen T.A. Paoletti R. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels Mayo Clin. Proc. 2003 78 965 978 10.1016/S0025-6196(11)63144-3 12911045 · DOI
  44. [54]Demonty I. Ras R.T. Van der Knaap H.C.M. Duchateau G.S.M.J. Meijer L. Zock P.L. Geleijnse J.M. Trautwein E.A. Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake J. Nutr. 2009 139 271 284 10.3945/jn.108.095125 19091798 · DOI
  45. [57]Ghaedi E. Kord-Varkaneh H. Mohammadi H. Askarpour M. Miraghajani M. Phytosterol Supplementation Could Improve Atherogenic and Anti-Atherogenic Apolipoproteins: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials J. Am. Coll. Nutr. 2020 39 82 92 10.1080/07315724.2019.1605313 31074692 · DOI
  46. [58]Plat J. Mackay D. Baumgartner S. Clifton P.M. Gylling H. Jones P.J. Progress and prospective of plant sterol and plant stanol research: Report of the Maastricht meeting Atherosclerosis 2012 225 521 533 10.1016/j.atherosclerosis.2012.09.018 23083678 · DOI
  47. [59]Trautwein E.A. Koppenol W.P. de Jong A. Hiemstra H. Vermeer M.A. Noakes M. Luscombe-Marsh N.D. Plant sterols lower LDL-cholesterol and triglycerides in dyslipidemic individuals with or at risk of developing type 2 diabetes; a randomized, double-blind, placebo-controlled study Nutr. Diabetes 2018 8 30 10.1038/s41387-018-0039-8 29795368 PMC5968034 · DOI
  48. [60]De Smet E. Mensink R.P. Plat J. Effects of plant sterols and stanols on intestinal cholesterol metabolism: Suggested mechanisms from past to present Mol. Nutr. Food Res. 2012 56 1058 1072 10.1002/mnfr.201100722 22623436 · DOI
  49. [63]Gomes G.B. Zazula A.D. Shigueoka L.S. Fedato R.A. da Costa A.B. Guarita-Souza L.C. Baena C.P. Olandoski M. Faria-Neto J.R. A Randomized Open-Label Trial to Assess the Effect of Plant Sterols Associated with Ezetimibe in Low-Density Lipoprotein Levels in Patients with Coronary Artery Disease on Statin Therapy J. Med. Food 2017 20 30 36 10.1089/jmf.2016.0042 28098515 · DOI
  50. [65]Expert Dyslipidemia Panel of the International Atherosclerosis Society An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia—Full report J. Clin. Lipidol 2014 8 29 60 10.1016/j.jacl.2013.12.005 24528685 · DOI
  51. [66]Ferguson J.J. Stojanovski E. MacDonald-Wicks L. Garg M.L. High molecular weight oat β-glucan enhances lipid-lowering effects of phytosterols. A randomised controlled trial Clin. Nutr. 2020 39 80 89 10.1016/j.clnu.2019.02.007 30792143 · DOI
  52. [67]Shrestha S. Volek J.S. Udani J. Wood R.J. Greene C.M. Aggarwal D. Contois J.H. Kavoussi B. Fernandez M.L. A combination therapy including psyllium and plant sterols lowers LDL cholesterol by modifying lipoprotein metabolism in hypercholesterolemic individuals J. Nutr. 2006 136 2492 2497 10.1093/jn/136.10.2492 16988115 · DOI
  53. [68]Chen S.C. Judd J.T. Kramer M. Meijer G.W. Clevidence B.A. Baer D.J. Phytosterol intake and dietary fat reduction are independent and additive in their ability to reduce plasma LDL cholesterol Lipids 2009 44 273 281 10.1007/s11745-008-3278-y 19145455 · DOI
  54. [70]Blom W.A.M. Koppenol W.P. Hiemstra H. Stojakovic T. Scharnagl H. Trautwein E.A. A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia Eur. J. Nutr. 2019 58 1615 1624 10.1007/s00394-018-1706-1 29725824 PMC6561982 · DOI
  55. [71]Hu F.B. Dietary pattern analysis: A new direction in nutritional epidemiology Curr. Opin. Lipidol. 2002 13 3 9 10.1097/00041433-200202000-00002 11790957 · DOI · Paper page
  56. [72]Zampelas A. Magriplis E. Dietary patterns and risk of cardiovascular diseases: A review of the evidence Proc. Nutr. Soc. 2020 79 68 75 10.1017/S0029665119000946 31250769 · DOI
  57. [74]Hemler E.C. Hu F.B. Plant-Based Diets for Cardiovascular Disease Prevention: All Plant Foods Are Not Created Equal Curr. Atheroscler. Rep. 2019 21 18 10.1007/s11883-019-0779-5 30895476 · DOI
  58. [75]Shen J. Wilmot K.A. Ghasemzadeh N. Molloy D.L. Burkman G. Mekonnen G. Gongora M.C. Quyyumi A.A. Sperling L.S. Mediterranean Dietary Patterns and Cardiovascular Health Annu. Rev. Nutr. 2015 35 425 449 10.1146/annurev-nutr-011215-025104 25974696 · DOI
  59. [76]Bere E. Brug J. Towards health-promoting and environmentally friendly regional diets-a Nordic example Public Health Nutr. 2009 12 91 96 10.1017/S1368980008001985 18339225 · DOI
  60. [77]Adamsson V. Reumark A. Cederholm T. Vessby B. Risérus U. Johansson G. What is a healthy Nordic diet? Foods and nutrients in the NORDIET study Food Nutr. Res. 2012 56 18189 10.3402/fnr.v56i0.18189 22761599 PMC3386552 · DOI
  61. [78]Magkos F. Tetens I. Bügel S.G. Felby C. Schacht S.R. Hill J.O. Ravussin E. Astrup A. A Perspective on the Transition to Plant-Based Diets: A Diet Change May Attenuate Climate Change, but Can It Also Attenuate Obesity and Chronic Disease Risk? Adv. Nutr. 2020 11 1 9 10.1093/advances/nmz090 31504086 PMC7442415 · DOI · Paper page
  62. [80]Glenn A.J. Viguiliouk E. Seider M. Boucher B.A. Khan T.A. Blanco Mejia S. Jenkins D.J.A. Kahleová H. Raheli´c D. Salas-Salvadó J. Relation of Vegetarian Dietary Patterns with Major Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies Front. Nutr. 2019 6 80 10.3389/fnut.2019.00080 31263700 PMC6585466 · DOI
  63. [82]Ramezani-Jolfaie N. Mohammadi M. Salehi-Abargouei A. The effect of healthy Nordic diet on cardio-metabolic markers: A systematic review and meta-analysis of randomized controlled clinical trials Eur. J. Nutr. 2018 58 2159 2174 10.1007/s00394-018-1804-0 30128767 · DOI
  64. [83]Kahleova H. Salas-Salvadó J. Rahelić D. Kendall C.W. Rembert E. Sievenpiper J.L. Dietary Patterns and Cardiometabolic Outcomes in Diabetes: A Summary of Systematic Reviews and Meta-Analyses Nutrients 2019 11 2209 10.3390/nu11092209 PMC6770579 31540227 · DOI · Paper page
  65. [84]Rees K. Takeda A. Martin N. Ellis L. Wijesekara D. Vepa A. Das A. Hartley L. Stranges S. Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease Cochrane Database Syst. Rev. 2019 3 10.1002/14651858.CD009825.pub3 PMC6414510 30864165 · DOI
  66. [86]Yokoyama Y. Levin S.M. Barnard N.D. Association between plant-based diets and plasma lipids: A systematic review and meta-analysis Nutr. Rev. 2017 75 683 698 10.1093/nutrit/nux030 28938794 PMC5914369 · DOI
  67. [87]Rosato V. Temple N.J. La Vecchia C. Castellan G. Tavani A. Guercio V. Mediterranean diet and cardiovascular disease: A systematic review and meta-analysis of observational studies Eur. J. Nutr. 2019 58 173 191 10.1007/s00394-017-1582-0 29177567 · DOI · Paper page
  68. [88]Becerra-Tomás N. Mejía S.B. Viguiliouk E. Khan T. Kendall C.W. Kahleova H. Raheli´c D. Sievenpiper J.L. Salas-Salvadó J. Mediterranean diet, cardiovascular disease and mortality in diabetes: A systematic review and meta-analysis of prospective cohort studies and randomized clinical trials Crit. Rev. Food Sci. Nutr. 2019 1 21 10.1080/10408398.2019.1565281 30676058 · DOI · Paper page
  69. [89]Gunge V.B. Andersen I. Kyrø C. Hansen C.P. Dahm C.C. Christensen J. Tjønneland A. Olsen A. Adherence to a healthy Nordic food index and risk of myocardial infarction in middle-aged Danes: The diet, cancer and health cohort study Eur. J. Clin. Nutr. 2017 71 652 658 10.1038/ejcn.2017.1 28247857 · DOI
  70. [90]Hansen C.P. Overvad K. Kyrø C. Olsen A. Tjønneland A. Johnsen S.P. Jakobsen M.U. Dahm C.C. Adherence to a Healthy Nordic Diet and Risk of Stroke: A Danish Cohort Study Stroke 2017 48 259 264 10.1161/STROKEAHA.116.015019 28049735 · DOI
  71. [91]Roswall N. Sandin S. Scragg R. Löf M. Skeie G. Olsen A. Adami H.O. Weiderpass E. No association between adherence to the healthy Nordic food index and cardiovascular disease amongst Swedish women: A cohort study J. Intern. Med. 2015 278 531 541 10.1111/joim.12378 25991078 · DOI
  72. [92]Dinu M. Abbate R. Gensini G.F. Casini A. Sofi F. Vegetarian, vegan diets and multiple health outcomes: A systematic review with meta-analysis of observational studies Crit. Rev. Food Sci. Nutr. 2017 57 3640 3649 10.1080/10408398.2016.1138447 26853923 · DOI · Paper page
  73. [93]Nelson M.E. Hamm M.W. Hu F.B. Abrams S.A. Griffin T.S. Alignment of healthy dietary patterns and environmental sustainability: A systematic review Adv. Nutr. 2016 7 1005 1025 10.3945/an.116.012567 28140320 PMC5105037 · DOI · Paper page
  74. [94]Springmann M. Wiebe K. Mason-D’Croz D. Sulser T.B. Rayner M. Scarborough P. Health and nutritional aspects of sustainable diet strategies and their association with environmental impacts: A global modelling analysis with country-level detail Lancet Planet. Health 2018 2 e451 e61 10.1016/S2542-5196(18)30206-7 30318102 PMC6182055 · DOI
  75. [99]Corrin T. Papadopoulos A. Understanding the attitudes and perceptions of vegetarian and plant-based diets to shape future health promotion programs Appetite 2017 109 40 47 10.1016/j.appet.2016.11.018 27871943 · DOI
  76. [100]Fehér A. Gazdecki M. Véha M. Szakály M. Szakály Z. A Comprehensive Review of the Benefits of and the Barriers to the Switch to a Plant-Based Diet Sustainability 2020 12 4136

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Authors
Trautwein, E. A., & McKay, S.
Affiliations
  • Trautwein (Germany) (DE)
  • Upfield Research & Development, 3071 JL Rotterdam, The Netherlands
Corresponding author
Trautwein, Elke A.
Venue
Nutrients
Publisher
MDPI AG
Published
2020-09-01
Volume
12
Issue
9
Pages
2671
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu12092671
PMC
PMC7551487
OpenAlex
W3082113448
Cited by
257
References
20
Citations by year
2026: 25 · 2025: 49 · 2024: 59 · 2023: 58 · 2022: 39 · 2021: 21 · 2020: 5
FWCI
5.14
Type
journal article
Language
en
Open access
Licence
Locations
  • Nutrients (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
  • Physical Sciences › Environmental Science › Ecology › Agriculture Sustainability and Environmental Impact
Keywords
plant-based diet, dyslipidemia, cardiovascular risk, LDL cholesterol, vegetable fats, dietary fiber, phytosterols, phytochemicals, Mediterranean diet, DASH diet, Portfolio diet, vegetarian diet, vegan diet, cardiovascular disease prevention, environmental sustainability of diets
MeSH terms
Diet, Healthy, Heart Disease Risk Factors, Cardiovascular Diseases, Humans, Cholesterol, LDL, Diet, Vegetarian, Dyslipidemias

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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