Cited by 152Aquaculture Nutrition and GrowthAlgal biology and biofuel productionAquaculture disease management and microbiota

The DOI matches its Crossref record; 164 of the 172 references it cites were found in a registry or an index.

Nutritional applications of species of Spirulina and Chlorella in farmed fish: A review

Alagawany, Mahmoud, Taha, Ayman E., Noreldin, Ahmed, El-Tarabily, Khaled A., Abd El-Hack, Mohamed E.·2021·Aquaculture

DOI 10.1016/j.aquaculture.2021.736841

Open this paper in CoChat — free account

Abstract

Microalgae contain 50% crude protein value, which is comparable with the amino acid profile of fish meal, and high levels of polyunsaturated fatty acids make their use in animal feeding and nutrition extremely effective. Owing to the high price of fish meal and fish oil, cheaper suitable alternatives are being sought, and species of Spirulina and Chlorella could be a major plant protein source in farmed fish nutrition. Many studies have assessed the suitability of these microalgae in the diet of various fish species. This review highlights the influence of Spirulina on the growth enhancement of different fish species. Numerous beneficial effects of microalgae supplementation have been reported, including growth promotion in carp (Labeo rohita) and tilapia (Oreochromis niloticus), stimulation of immunity in rainbow trout (Oncorhynchus mykiss) and enhancement of reproductive performance in yellowtail cichlid (Pseudotropheus acei). Novel investigations have concluded that Spirulina could be utilized in the treatment of wastewater containing outflow from fish culture activities because of its effectiveness in eliminating heavy metals and metabolising excess feed present in water outflow. The aquaculture industry could integrate the treatment of water outflow with production of Spirulina as an additive to fish diets.

Integrity signals

Registry

Crossref · 10.1016/j.aquaculture.2021.736841

Cites

164 of 164 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Commercial Applications of Microalgae
Spolaore, P., Joannis-Cassan, C., Duran, E., & Isambert, A. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.101.87 · Cited by 4,285
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707
Effect of aquaculture on world fish supplies.
Naylor, R. L., Goldburg, R. J., Primavera, J. H., Kautsky, N., Beveridge, M. C. M., Clay, J., Folke, C., Lubchenco, J., Mooney, H., & Troell, M. (2000) · Nature · doi:10.1038/35016500 · Cited by 3,063
Environmentally induced oxidative stress in aquatic animals
Lushchak, V. I. (2011) · Aquatic Toxicology · doi:10.1016/j.aquatox.2010.10.006 · Cited by 2,729
Current research status of fish immunostimulants
Sakai, M. (1999) · Aquaculture · doi:10.1016/s0044-8486(98)00436-0 · Cited by 1,345
Effect of broodstock nutrition on reproductive performance of fish
Izquierdo, M. S., Fernández-Palacios, H., & Tacon, A. G. J. (2001) · Aquaculture · doi:10.1016/s0044-8486(01)00581-6 · Cited by 1,083
The Biochemistry of the Carotenoids
Goodwin, T. W. (1984) · Springer eBooks · doi:10.1007/978-94-009-5542-4 · Cited by 1,010
Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
Takatori, H., Kanno, Y., Watford, W. T., Tato, C. M., Weiss, G. E., Ivanov, I. I., Littman, D. R., & O’Shea, J. J. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072713 · Cited by 769
Spirulina, the edible microorganism.
Ciferri, O. (1983) · Microbiological Reviews · doi:10.1128/mmbr.47.4.551-578.1983 · Cited by 745
Spirulina Platensis Arthrospira
(1997) · doi:10.1201/9781482272970 · Cited by 704

Show all 172 references

Research works printed but not linked: 4

Bakir, 1993, Fatty acid composition, lipids and sensory characteristics of white amur (Ctenopharynogodon idella) fed different diets, J. Food Sci., 58, 90
Henriques, 2007, Extraction and quantification of pigments from a marine microalga: a simple and reproducible method. Communicating current research and educational topics and trends in applied microbiology Formataex, Badajoz, 586
Priyadarshani, 2012, Commercial and industrial applications of microalgae a review, J, Algal Biomass, 3, 89
Promya, 2011, The effects of Spirulina platensis and Cladophora algae on the growth performance, meat quality and immunity stimulating capacity of the African Sharptooth catfish (Clarias gariepinus), Int. J. Agric. Biol., 13, 77

Sorted by citations

Effect of environmental factors on growth performance of Nile tilapia (Oreochromis niloticus)
El-Hack, M. E. A., El‐Saadony, M. T., Nader, M. M., Salem, H. M., El-Tahan, A. M., Soliman, S. M., & Khafaga, A. F. (2022) · International Journal of Biometeorology · doi:10.1007/s00484-022-02347-6 · Cited by 227
Functional Properties of Bioactive Compounds from Spirulina spp.: Current Status and Future Trends
Bortolini, D. G., Maciel, G. M., Fernandes, I. D. A. A., Pedro, A. C., Rubio, F. T. V., Branco, I. G., & Haminiuk, C. W. I. (2022) · Food Chemistry: Molecular Sciences · doi:10.1016/j.fochms.2022.100134 · Cited by 201
Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp.
Abreu, A. P., Martins, R., & Nunes, J. (2023) · Bioengineering · doi:10.3390/bioengineering10080955 · Cited by 119
Microalgae trends toward functional staple food incorporation: Sustainable alternative for human health improvement
Gohara-Beirigo, A. K., Matsudo, M. C., Cezare-Gomes, E. A., de Carvalho, J. C. M., & Danesi, E. D. G. (2022) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2022.04.030 · Cited by 100
Overview of single cell protein: Production pathway, sustainability outlook, and digital twin potentials
Aidoo, R., Kwofie, E. M., Adewale, P., Lam, E., & Ngadi, M. O. (2023) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2023.07.003 · Cited by 92
Improvement of fish production and water quality in a recirculating aquaculture pond enhanced with bacteria-microalgae association
Wang, C., Jiang, C., Gao, T., Peng, X., Ma, S., Sun, Q., Xia, B., Xie, X., Bai, Z., Xu, S., et al. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.737420 · Cited by 86
Antiviral Activities of Algal-Based Sulfated Polysaccharides
Panggabean, J. A., Adiguna, S. P., Rahmawati, S. I., Ahmadi, P., Zainuddin, E. N., Bayu, A., & Putra, M. Y. (2022) · Molecules · doi:10.3390/molecules27041178 · Cited by 76
Fishmeal Dietary Replacement Up to 50%: A Comparative Study of Two Insect Meals for Rainbow Trout (Oncorhynchus mykiss)
Melenchón, F., de Mercado, E., Pula, H. J., Cardenete, G., Barroso, F. G., Fabrikov, D., Lourenço, H. M., Pessoa, M. F., Lagos, L. X., Weththasinghe, P., et al. (2022) · Animals · doi:10.3390/ani12020179 · Cited by 69
Effects of fish meal replacement with Chlorella meal on growth performance, pigmentation, and liver health of largemouth bass (Micropterus salmoides)
Xi, L., Lu, Q., Liu, Y., Su, J., Chen, W., Gong, Y., Han, D. H., Yang, Y., Zhang, Z., Jin, J., et al. (2022) · Animal nutrition · doi:10.1016/j.aninu.2022.03.003 · Cited by 69
The Potential of Marine Microalgae for the Production of Food, Feed, and Fuel (3F)
Mahata, C., Das, P., Khan, S., Thaher, M. I., Quadir, M. A., Nagappan, S., & Jabri, H. M. S. J. A. (2022) · Fermentation · doi:10.3390/fermentation8070316 · Cited by 70
Chlorella vulgaris as a food substitute: Applications and benefits in the food industry
Wang, C., Onyeaka, H., Miri, T., & Soltani, F. (2024) · Journal of Food Science · doi:10.1111/1750-3841.17529 · Cited by 65
MicroRNAs mediated environmental stress responses and toxicity signs in teleost fish species
Raza, S. H. A., Abdelnour, S. A., Alotaibi, M. A., AlGabbani, Q., Naiel, M. A. E., Shokrollahi, B., Noreldin, A. E., Jahejo, A. R., Shah, M. A., Alagawany, M. M., et al. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.737310 · Cited by 66
Self-citation
Chlorella in aquaculture: challenges, opportunities, and disease prevention for sustainable development
Aly, S. M., ElBanna, N. I., & Fathi, M. (2023) · Aquaculture International · doi:10.1007/s10499-023-01229-x · Cited by 72
Metabolomics in salmonid aquaculture research: Applications and future perspectives
Lulijwa, R., Alfaro, A. C., & Young, T. (2021) · Reviews in Aquaculture · doi:10.1111/raq.12612 · Cited by 54
Dietary Chlorella vulgaris modulates the performance, antioxidant capacity, innate immunity, and disease resistance capability of Nile tilapia fingerlings fed on plant-based diets
Abdel‐Tawwab, M., Mousa, M. A. A., Mamoon, A., Abdelghany, M. F., Abdel-Hamid, E. A. A., Abdel‐Razek, N., Ali, F. S., Shady, S. H. H., & Gewida, A. G. A. (2021) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2021.115181 · Cited by 54
Removal of nitrate and phosphate from simulated agricultural runoff water by Chlorella vulgaris
Vazirzadeh, A., Jafarifard, K., Ajdari, A., & Yusuf Chisti, B. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.149988 · Cited by 51
Benefits of the microalgae Spirulina and Schizochytrium in fish nutrition: a meta-analysis
Trevi, S., Webster, T. M. U., Consuegra, S., & de Leániz, C. G. (2023) · Scientific Reports · doi:10.1038/s41598-023-29183-x · Cited by 54
Micro-algae: Revolutionizing food production for a healthy and sustainable future
Naik, B., Mishra, R., Kumar, V., Mishra, S., Gupta, U., Rustagi, S., Gupta, A. K., Preet, M. S., Bhatt, S. C., & Rizwanuddin, S. (2024) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2023.100939 · Cited by 65
Growth kinetics and quantification of carbohydrate, protein, lipids, and chlorophyll of Spirulina platensis under aqueous conditions using different carbon and nitrogen sources
Rosero-Chasoy, G., Rodríguez-Jasso, R. M., Aguilar, C. N., Buitrón, G., Chairez, I., & Ruiz, H. A. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2021.126456 · Cited by 44
Microalgae as fishmeal alternatives in aquaculture: current status, existing problems, and possible solutions
Gao, S., Chen, W., Cao, S., Sun, P., & Gao, X. (2024) · Environmental Science and Pollution Research · doi:10.1007/s11356-024-32143-1 · Cited by 52
Effect of Spirulina Meal Supplementation on Growth Performance and Feed Utilization in Fish and Shrimp: A Meta-Analysis
Li, L., Liu, H., & Zhang, P. (2022) · Aquaculture Nutrition · doi:10.1155/2022/8517733 · Cited by 40
Spirulina-enriched Substrate to Rear Black Soldier Fly (Hermetia illucens) Prepupae as Alternative Aquafeed Ingredient for Rainbow Trout (Oncorhynchus mykiss) Diets: Possible Effects on Zootechnical Performances, Gut and Liver Health Status, and Fillet Quality
Ratti, S., Zarantoniello, M., Chemello, G., Giammarino, M., Palermo, F. A., Cocci, P., Mosconi, G., Tignani, M. V., Pascon, G., Cardinaletti, G., et al. (2023) · Animals · doi:10.3390/ani13010173 · Cited by 40
Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus)
Hamed, M., Soliman, H. A. M., Eid, Z., Naggar, Y. A., & Sayed, A. E. H. (2022) · Frontiers in Environmental Science · doi:10.3389/fenvs.2022.869727 · Cited by 38
Protective effects of Chlorella vulgaris as a feed additive on growth performance, immunity, histopathology, and disease resistance against Vibrio parahaemolyticus in the Pacific white shrimp
Eissa, E. H., Aljàrari, R. M., Elfeky, A., El‐Aziz, Y. M. A., Munir, M. B., Jastaniah, S. D. S., Alaidaroos, B. A., Shafi, M. E., El-Hamed, N. N. B. A., AL-Farga, A. M., et al. (2023) · Aquaculture International · doi:10.1007/s10499-023-01298-y · Cited by 40
Effective valorization of Chlorella biomass and Brewers spent grain substituting fish meal and soybean meal in the diet of herbivorous fish Cirrhinus reba for higher growth, digestibility and sustainable cultivation
Chattaraj, S., Behera, B. K., & MOHAPATRA, P. K. D. (2023) · Journal of Applied Phycology · doi:10.1007/s10811-023-03106-9 · Cited by 36
Effects of spirulina (Arthrospira platensis) as a fishmeal replacer in practical diets on growth performance, proximate composition, and amino acids profile of pabda catfish (Ompok pabda)
Akter, T., Hossain, A., Islam, M. R., Hossaın, M. A., Das, M., Rahman, M., Aye, A. T., & Abdel‐Tawwab, M. (2021) · Journal of Applied Aquaculture · doi:10.1080/10454438.2021.1936740 · Cited by 35
Use of rice protein concentrates inOreochromis niloticusdiets and its effect on growth, intestinal morphology, biochemical indices and ghrelin gene expression
Rahman, A. N. A., Maricchiolo, G., El‐fattah, A. H. A., Alagawany, M. M., & Reda, R. M. (2021) · Aquaculture Nutrition · doi:10.1111/anu.13361 · Cited by 33
Self-citation
Effects of Probiotics, Prebiotics, and Synbiotics as an Alternative to Antibiotics on Growth and Blood Profile of Nile Tilapia (Oreochromis niloticus)
Munni, M. J., Akther, K. R., Ahmed, S., Hossain, M. A., & Roy, N. C. (2023) · Aquaculture Research · doi:10.1155/2023/2798279 · Cited by 35
Diets containing Arthrospira platensis increase growth, modulate lipid metabolism, and reduce oxidative stress in pacu (Piaractus mesopotamicus) exposed to ammonia
Carneiro, W. F., Castro, T. F. D., Reichel, T., Uzeda, P. L. D. C., Martínez-Palacios, C. A., & Murgas, L. D. S. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.737402 · Cited by 30
Effect of dietary Spirulina (Arthrospira platensis) on the growth performance, immune‐related gene expression and resistance toVibrio anguillarumin European seabass (Dicentrarchus labrax)
Güroy, B., Güroy, D., Bi̇len, S., Kenanoğlu, O. N., Şahin, I., Terzi, E., Karadal, O., & Mantoğlu, S. (2022) · Aquaculture Research · doi:10.1111/are.15745 · Cited by 29
Physiological response of rainbow trout (Oncorhynchus mykiss) to graded levels of novel Chlorella sorokiniana meal as a single fishmeal alternative or combined with black soldier fly larval meal
Liu, Y., Chang, H., Lv, W., Ma, S., Qiu, G., Lu, S., Han, S., Wang, C., Han, D., Zhang, Y., et al. (2022) · Aquaculture · doi:10.1016/j.aquaculture.2022.738715 · Cited by 27
Growth, carcass criteria, and blood biochemical parameters of growing quails fed Arthrospira platensis as a feed additive
Elzaher, H. A. A., Ibrahim, Z. A., Ahmed, S. A., Salah, A. S., Osman, A., Swelum, A. A., Suliman, G. M., Téllez‐Isaías, G., Alagawany, M. M., & El-Hack, M. E. A. (2023) · Poultry Science · doi:10.1016/j.psj.2023.103205 · Cited by 29
Self-citation
Algae Application for Treating Wastewater Contaminated with Heavy Metal Ions
Beni, A. A., Haghmohammadi, M., Asl, S. D., Hakimzadeh, S. M., & Nezarat, A. (2024) · Environmental science and engineering · doi:10.1007/978-981-97-2371-3_12 · Cited by 28
Effects of varying dietary microalgae levels on performance, egg quality, fertility, and blood biochemical parameters of laying Japanese quails (Coturnix coturnix Japonica)
El-Hack, M. E. A., Majrashi, K. A., Fakiha, K. G., Roshdy, M., Kamal, M., Saleh, R. M., Khafaga, A. F., Othman, S. I., Rudayni, H. A., Allam, A. A., et al. (2024) · Poultry Science · doi:10.1016/j.psj.2024.103454 · Cited by 28
Self-citation
Spirulina Maxima as a Valuable Ingredient: Determination of Broad Fatty Acid and Amino Acid Profiles and Nutritional Quality and Anti-Amylase Capacity
Tavakoli, Z., Kavoosi, G., Siahbalaei, R., & Karimi, J. (2025) · Applied Food Research · doi:10.1016/j.afres.2025.100741 · Cited by 27
High replacement of fishmeal by Chlorella meal affects intestinal microbiota and the potential metabolic function in largemouth bass (Micropterus salmoides)
Zhang, Z., Xi, L., Liu, H., Jin, J., Yang, Y., Zhu, X., Han, D. H., & Xie, S. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1016662 · Cited by 29
Improvement of the probiotic growth-stimulating capacity of microalgae extracts by pulsed electric fields treatment
Ricós-Muñoz, N., Rivas, A., Castagnini, J. M., Moral, R., Barba, F. J., & Pina-Pérez, M. C. (2022) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2022.103256 · Cited by 26
Nanomagnetic approach applied to microalgae biomass harvesting: advances, gaps, and perspectives
Barizão, A. C. D. L., de Oliveira, J. P., Gonçalves, R. F., & Cassini, S. T. A. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-15260-z · Cited by 25
Challenging problems of applying microalgae for aquaculture environment protection and nutrition supplementation: A long road traveled and still a far way to go
Lu, Q., Lu, Y., & Yang, L. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1151440 · Cited by 30
Effects of partial replacement of fishmeal with Spirulina platensis powder and addition of Spirulina platensis polysaccharide on growth, nutrition, antioxidant capacity and gut microbiota of Micropterus salmoides
Zhang, W., Deng, Y., Yang, Z., Kong, Q., Liu, P., Liao, H., & Tang, H. (2024) · Aquaculture · doi:10.1016/j.aquaculture.2024.740802 · Cited by 24
Chlorella vulgaris as unconventional protein source in fish feed: A review
Albaqami, N. M. (2024) · Aquaculture · doi:10.1016/j.aquaculture.2024.741404 · Cited by 25
Enhancing Rearing of European Seabass (Dicentrarchus labrax) in Aquaponic Systems: Investigating the Effects of Enriched Black Soldier Fly (Hermetia illucens) Prepupae Meal on Fish Welfare and Quality Traits
Zarantoniello, M., Oliveira, A., Şahin, T., Freddi, L., Torregiani, M., Tucciarone, I., Chemello, G., Cardinaletti, G., Gatto, E., Parisi, G., et al. (2023) · Animals · doi:10.3390/ani13121921 · Cited by 22
Retrospect of fishmeal substitution in largemouth bass (Micropterus salmoides): a review
Liu, Y., Pu, C., Pei, Z., Zhang, W., Wei, Z., Chen, H., & Huang, Y. (2024) · Fish Physiology and Biochemistry · doi:10.1007/s10695-024-01429-z · Cited by 18
Consumer preference for altered color of rainbow trout (Oncorhynchus mykiss) fillet induced by Spirulina (Arthrospira platensis)
Rosenau, S., Wolgast, T., Altmann, B. A., & Risius, A. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.739522 · Cited by 20
Effect of cheese whey on phycobiliproteins production and FAME profile by Arthrospira platensis (Spirulina): Promoting the concept of a circular bio-economy
Cavallini, A., Torre, S., Usai, L., Casula, M., Fais, G., Nieri, P., Concas, A., & Lutzu, G. A. (2024) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2024.101625 · Cited by 19
Spirulina in fish immunity development: find the black box
Rana, M., Mandal, S., & Kabita, S. (2024) · Reviews in Fish Biology and Fisheries · doi:10.1007/s11160-023-09832-0 · Cited by 19
Environmentally Friendly Technologies for Wastewater Treatment in Food Processing Plants: A Bibliometric Analysis
Zapata-Mendoza, P. C. O., Berrios-Tauccaya, O. J., Tirado-Kulieva, V. A., Gonzales-Malca, J. A., Ricse-Reyes, D. R., Berrios-Zevallos, A. A., & Sanz, R. S. S. (2022) · Sustainability · doi:10.3390/su142214698 · Cited by 16
Nanosynthesis, phycochemical constituents, and pharmacological properties of cyanobacterium Oscillatoria sp.
Bishoyi, A. K., Mandhata, C. P., Sahoo, C. R., Paidesetty, S. K., & Padhy, R. N. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02719-8 · Cited by 15
Combined Dietary Spirulina platensis and Citrus limon Essential Oil Enhances the Growth, Immunity, Antioxidant Capacity and Intestinal Health of Nile Tilapia
Abdo, S. E., Nahas, A. F. E., Abdellatif, R. E., Mohamed, R. A., Helal, M. A., Azzam, M. M., Cerbo, A. D., & El‐Kassas, S. (2024) · Veterinary Sciences · doi:10.3390/vetsci11100474 · Cited by 15
Acrylamide exposure induces growth retardation, neurotoxicity, stress, and immune/antioxidant disruption in Nile tilapia (Oreochromis niloticus): The alleviative effects of Chlorella vulgaris diets
Edrees, A., Shaban, N. S., Hassan, N. E.-H. Y., Abdel‐Daim, A. S. A., Sobh, M. S., & Ibrahim, R. E. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109411 · Cited by 14
Dairy Wastewaters to Promote Mixotrophic Metabolism in Limnospira (Spirulina) platensis: Effect on Biomass Composition, Phycocyanin Content, and Fatty Acid Methyl Ester Profile
Baraldi, L., Usai, L., Torre, S., Fais, G., Casula, M., Dessì, D., Nieri, P., Concas, A., & Lutzu, G. A. (2025) · Life · doi:10.3390/life15020184 · Cited by 14
Amelioration of hypoxia and cold stress in Nile tilapia: comparative effect of Chlorella vulgaris and its nanoparticle dietary supplementation on performance, antioxidant, hepatic functions, and meat quality
Youssuf, H. A., Soror, E. I., Shehab, A., El-daim, A. M., Abo-Gamil, Z., Ahmed-Farid, O. A.-H., Hamad, A. M. A., Edris, S. N., & Matter, A. F. (2024) · Aquaculture International · doi:10.1007/s10499-024-01739-2 · Cited by 13
The Effect of Sargassum siliquastrum Supplementation on Growth Performance, Cecal Fermentation, Intestine Histomorphology, and Immune Response of Japanese Quails
Hafsa, S. A. A., & Hassan, A. (2022) · Animals · doi:10.3390/ani12040432 · Cited by 12
Combined Effects of Spirulina platensis and Pediococcus acidilactici on the Growth Performance, Digestive Enzyme Activity, Antioxidative Status, and Immune Genes in Zebrafish
Ahmadifar, M., Esfahani, D. E., Ahmadifar, E., Sheikhzadeh, N., Mood, S. M., & Moradi, S. Z. (2023) · Annals of Animal Science · doi:10.2478/aoas-2023-0019 · Cited by 12
Spirulina platensis and Chlorella vulgaris in poultry nutrition - a review of current research and potential opportunities
Wlaźlak, S., & Biesek, J. (2025) · Poultry Science · doi:10.1016/j.psj.2025.105456 · Cited by 13
Algae as a sustainable feed resource: revolutionizing animal nutrition
Kazemi, M. (2025) · Aquaculture International · doi:10.1007/s10499-025-02195-2 · Cited by 12
Effects of substituting fish meal with Chlorella meal on growth performance, whole-body composition, pigmentation, and physiological health of marbled eel (Anguilla marmorata)
Huang, K., Liu, X., Ma, R., Wang, B., Ho, S., Chen, J., & Xie, Y. (2024) · Algal Research · doi:10.1016/j.algal.2024.103523 · Cited by 10
Schizochytrium sp. can improve feed utilization, fillet DHA content, and non-specific immunity of juvenile Nile tilapia (Oreochromis niloticus) fed fish oil free diet
Peng, D., Zhang, X., Zhu, F., Wen, H., Dong, L., Tian, J., Zhang, J., Yang, C., Xiao, J., Duan, X., et al. (2024) · Journal of Applied Phycology · doi:10.1007/s10811-024-03334-7 · Cited by 11
Effects of supplementing the rainbow trout (Oncorhynchus mykiss) diet with Spirulina and Chlorella on the tissue's cadmium detoxification capacity, growth performance, fatty acid composition, antioxidant defense system and liver histology
Harmantepe, F. B., Gündoğdu, A., Karslı, Z., & Sağır, D. (2024) · Aquaculture · doi:10.1016/j.aquaculture.2024.741687 · Cited by 13
Toward sustainable food systems: can spirulina (Arthrospira platensis) become a sustainable source of protein to enhance the nutritional benefits of cultured Nile tilapia (Oreochromis niloticus)?
Soma, K., Kals, J., Opiyo, M. A., Ndambi, A., García-Cubero, R., Barbosa, M. J., Rurangwa, E., & Vernooij, A. G. (2024) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2024.1283150 · Cited by 12
Improving the water quality of fish aquaculture effluents after treatment by microalgae
Farrag, M. M. S., Abdelmgeed, A. M., Moustafa, M. A., & Osman, A. G. M. (2024) · Desalination and Water Treatment · doi:10.1016/j.dwt.2024.100155 · Cited by 10
Spirulina (Arthrospira platensis) supplementation: Impact on growth, metabolism, and antioxidant status in zebrafish
Coli, A., Carneiro, W. F., da Silva, K. C. D., Castro, T. F. D., de Oliveira, J. P. L., Martins, M. S. D. A., & Murgas, L. D. S. (2024) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13964 · Cited by 9
Effects of Substituting Fish Meal by Chlorella Meal in Practical Diet on Growth, Feed Utilization, and Flesh Quality of Pacific White Shrimp (Penaeus vannamei)
Li, M., Li, X., Yao, W., Wang, Y., Li, L. M., & Leng, X. (2024) · Aquaculture Nutrition · doi:10.1155/2024/9969518 · Cited by 9
Phycocyanin: A potential bioresource for functional food product development
Chhirang, P., Gahlawat, V. K., & Singh, B. P. (2024) · South African Journal of Botany · doi:10.1016/j.sajb.2024.08.047 · Cited by 8
Unveiling the Potential of Silymarin, Spirulina platensis, and Chlorella vulgaris towards Cardiotoxicity via Modulating Antioxidant Activity, Inflammation, and Apoptosis in Rats
El-Gendy, H. F., Khalifa, H. K., Omran, A., Korany, R. M. S., Selim, S., Hussein, E. A., Alhotan, R. A., Ayyoub, A., & Masoud, S. R. (2024) · Life · doi:10.3390/life14101289 · Cited by 9
Box–Behnken design based statistical modelling to study the effects of spirulina (Arthrospira platensis) incorporation on nutritional standards of vegan snack product
Pandey, V. K., Singh, P., Srivastava, S., Zanwar, S., Dar, A. H., Singh, R., & Lal, A. (2023) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2023.100700 · Cited by 12
Effect of supercritical CO2 extraction as pretreatment to obtain C-phycocyanin from spirulina (Arthrospira maxima)
López-Limón, J. A., Hernández-Cázares, A. S., Hidalgo‐Contreras, J. V., la Vega, G. R.-D., Mellado-Pumarino, R. D. A., & Ríos-Corripio, M. A. (2024) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2024.106428 · Cited by 8
Critical assessment of metabolism and related growth and quality traits in trout fed spirulina-supplemented plant-based diets
Roques, S., Deborde, C., Skiba, S., Cala, O., Marchand, Y., Moing, A., & Fauconneau, B. (2022) · Aquaculture · doi:10.1016/j.aquaculture.2022.738033 · Cited by 8
In Pursuit of Fish-Free Feeds: A Multi-Species Evaluation
Campbell, K. B., McLean, E., & Barrows, F. T. (2022) · Fishes · doi:10.3390/fishes7060336 · Cited by 8
Outbreak simulation of Litopenaeus vannamei recovery rate with oral alginate and spirulina diet supplementation against Vibrio parahaemolyticus AHPND
Azhar, N., & Yudiati, E. (2023) · Aquaculture International · doi:10.1007/s10499-023-01050-6 · Cited by 8
A Study on the Dietary Yeast Polysaccharide Supplementation in Growth Performance, Antioxidant Capacity, and Immunity of Juvenile Largemouth Bass (Micropterus salmoides)
Qin, J., Mi, H., Ren, M., Huang, D., Liang, H., Zhang, L., Teng, T., & Heng, Y. (2025) · Fishes · doi:10.3390/fishes10010026 · Cited by 7
Exploring the biotechnological applications of Spirulina maxima: a comprehensive review
Jacuinde-Ruíz, J. C., & González‐Hernández, J. C. (2024) · Brazilian Journal of Biology · doi:10.1590/1519-6984.287134 · Cited by 7
Spirulina (Arthrospira), as feed additive in finfish and shellfish aquaculture
Ringø, E. (2025) · Aquaculture and Fisheries · doi:10.1016/j.aaf.2025.06.005 · Cited by 9
Live-food enriched with Chlorella vulgaris as a potential supplemental diet to enhance performance and immune response of Tor tambroides larvae (Bleeker 1854)
Joshua, W. J., Zulperi, Z. M., Kamarudin, M. S., Ikhsan, N. F. M., Chin, Y. K., Ina-Salwany, M. Y., & Yusoff, F. M. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.740276 · Cited by 10
Enhanced Photosynthetic Pigment Production Using a Scaled-Up Continuously Circulated Bioreactor
Lee, W.-K., Ryu, Y.-K., Kim, T., Park, A., Lee, Y.-J., Sunwoo, I. Y., Koh, E., Oh, C., Choi, W.-Y., & Kang, D.-H. (2023) · Marine Drugs · doi:10.3390/md21110576 · Cited by 8
Effects of the Replacement of Dietary Fishmeal by the Blend of Tenebrio molitor Meal, Chlorella Meal, Clostridium Autoethanogenum Protein, and Cottonseed Protein Concentrate on Growth, Protein Utilization, and Intestinal Health of Gibel Carp (Carassius gibelio, CAS Ⅴ)
Yu, Y., Wang, X., Jin, J., Han, D. H., Zhu, X., Liu, H., Zhang, Z., Yang, Y., & Xie, S. (2024) · Aquaculture Nutrition · doi:10.1155/2024/5019899 · Cited by 6
Green microbes: Potential solutions for key sustainable development goals
Díaz‐Troya, S., & Huertas, M. J. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.14546 · Cited by 8
Advancements of application of microalgae biotechnology in the aquaculture water quality control
Qian, J., Chen, F., & Zhou, W. (2022) · Advances in bioenergy · doi:10.1016/bs.aibe.2022.05.002 · Cited by 7
Valorisation of white grape pomace sugars for optimized heterotrophic cultivation of Auxenochlorella protothecoides: A sustainable food ingredient
Manso, M., Ibarruri, J., de Marañón, Í. M., & Cebrían, M. (2024) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2024.103906 · Cited by 6
Microalgae as superfood
Schneider, A. T., Deprá, M. C., Dias, R. R., Zepka, L. Q., & Lopes, E. J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18816-9.00023-x · Cited by 8
Effects of Fishmeal Replacement with Spirulina ( Arthrospira platensis ) and Sargassum ilicifolium Meal on Growth and Health Indices of Asian Seabass ( Lates calcarifer ) Juveniles
Mohammadian, T., Mozanzadeh, M. T., Mousavi, P. S. S. M. M. S., Mesbah, M., & Khosravi, M. (2024) · Annals of Animal Science · doi:10.2478/aoas-2024-0099 · Cited by 6
Applications of microalgae and microalgal nanostructures in environment and healthcare
Chopra, S., Kaur, S., Kumar, V., & Guleria, P. (2024) · Next research. · doi:10.1016/j.nexres.2024.100058 · Cited by 6
Future foods: Global trends, opportunities, and sustainability challenges
Pradhan, A., Saha, D., Sarkar, A., & Rout, R. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-31652-4.00004-0 · Cited by 6
The protein transition—environmental footprints of farmed fish, microalgae and chicken for food, a case study in Kenya
Hu, X., Soma, K., Odinga, B., Obwanga, B., Agricola, H. J., & Kanyuguto, C. M. (2024) · Environment Development and Sustainability · doi:10.1007/s10668-024-05574-6 · Cited by 8
Biocomposites from Microalgae
Ibrahim, N. N., Ahmad, I., Abdullah, N., Koji, I., Mohamad, S. E., & Akhir, F. N. M. (2023) · Composites science and technology · doi:10.1007/978-981-19-5327-9_5 · Cited by 5
Does Genetic Background of Rainbow Trout Impact Growth and Feed Utilisation following Fishmeal Substitution by Partly Defatted Insect Meal (Hermetia illucens) or Microalgae Powder (Arthrospira platensis)?
Dietz, C., Wessels, S., Sünder, A., Sharifi, A. R., Gährken, J., & Liebert, F. (2023) · Aquaculture Research · doi:10.1155/2023/4774048 · Cited by 5
Recovery of nutrients from fish sludge to enhance the growth of microalga Chlorella sorokiniana CMBB276
Lian, J., He, Y., Wang, L., Liu, Y., Wang, K., Sunde, J., Rebours, C., Liu, H., Zhu, X., Han, D., et al. (2024) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2024.116421 · Cited by 4
A Pretty Kettle of Fish: A Review on the Current Challenges in Mediterranean Teleost Reproduction
Lombó, M., Giommi, C., Zarantoniello, M., & Chemello, G. (2024) · Animals · doi:10.3390/ani14111597 · Cited by 4
Dietary Chlorella vulgaris and Saccharomyces cerevisiae enhanced the growth performance, blood biomarkers, and antioxidative capacity of common carp (Cyprinus carpio)
El-Mashtoly, M., Magouz, F. I., Darwish, S., Amer, A. A., Zaineldin, A. I., Gewaily, M. S., & Dawood, M. A. O. (2024) · Scientific African · doi:10.1016/j.sciaf.2024.e02407 · Cited by 4
Replacing Fish Meal with Spirulina (Arthrospira platensis): Nutrigenomic Modulation of Growth, Reproductive Performance, and Metabolism in Zebrafish
Carneiro, W. F., Navarrete‐Ramírez, P., Castro, T. F. D., Leão, E. R., Martínez‐Chávez, C. C., Martínez-Palacios, C. A., & Murgas, L. D. S. (2025) · Animals · doi:10.3390/ani15172552 · Cited by 5
Possibilities of using 5‐Fluoro‐2'‐deoxyuridine in controlling rotifer contamination in cultivation of Spirulina platensis
Lian, H., Li, R., Chai, Y., Zhang, Y., Lu, Y., Pan, Z., Zhang, R., Yang, J., & Han, C. (2022) · Aquaculture Research · doi:10.1111/are.15858 · Cited by 4
The use of biologically active substances in poultry feeding (review)
Михайловна, К. Н., Шарипович, К. К., & Duskaev, G. K. (2024) · Agrarian Bulletin of the · doi:10.32417/1997-4868-2024-24-08-1037-1044 · Cited by 3
Nutritional strategies for enhancing the quality of animal-derived food products
Kazemi, M., & Valizadeh, Ř. (2025) · Discover Food · doi:10.1007/s44187-025-00759-y · Cited by 5
Effect of replacing fishmeal with spirulina ( Arthrospira platensis ) powder on growth, survival, body coloration, and meat quality in the freshwater prawn Macrobrachium caementarius
Mimbela‐Ipanaque, R., Narváez‐Rodríguez, D., & Reyes-Avalos, W. (2025) · Journal of the World Aquaculture Society · doi:10.1111/jwas.70066 · Cited by 3
Biotechnological Applications of Cyanobacteria: Synechocystis and Synechococcus Strains
Bolay, P., Toepel, J., & Bühler, B. (2025) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2025_282 · Cited by 4
Comprehensive Analysis of Chlorella vulgaris and Arthrospira platensis: Algae for Food Well-Being and Sustainable Agriculture
Čmiková, N., Vukić, M., Vuković, N. L., Havlík, J., Noguera‐Artiaga, L., Carbonell-Barrachina, Á. A., Jančo, I., Vinciguerra, V., Garzoli, S., & Kačániová, M. (2025) · ACS Food Science & Technology · doi:10.1021/acsfoodscitech.5c00309 · Cited by 3
The Blue-Green Microalga (Spirulina) in the Fishery: A Mini Review
al., M. M. E.-S. E. (2023) · Egyptian Journal of Aquatic Biology and Fisheries · doi:10.21608/ejabf.2023.307318 · Cited by 5
Growth, intestinal health, body composition, and molecular mechanism of the hybrid grouper, E. lanceolatus♂ × E. fuscoguttatus♀juveniles reared with microalgae Chlorella pyrenoidosa
Zhang, W. H., Lau, C. C., Sung, Y. Y., Zhou, W., Gao, J. W., Jiang, Z. F., Chen, S., & Mok, W. J. (2023) · Aquaculture International · doi:10.1007/s10499-023-01327-w · Cited by 3
Impact of Arthrospira maxima Feed Supplementation on Gut Microbiota and Growth Performance of Tilapia Fry (Oreochromis niloticus)
Rojas-Villalta, D., Gómez-Espinoza, O., Guillén-Watson, R., Murillo-Vega, F., Villalta-Romero, F., Vaquerano-Pineda, F., Chicas-Romero, M., Guerrero, M., & Núñez-Montero, K. (2024) · Fishes · doi:10.3390/fishes9100374 · Cited by 5
Spirulina plantesis flour supplementation to increase the growth and brightness of the color of Betta fish (Betta splendens) Regan, 1910
Sutarjo, G. A., Prasetyo, D., Handajani, H., & Diba, D. F. (2024) · BIO Web of Conferences · doi:10.1051/bioconf/202414302004 · Cited by 3

Authors: Alagawany, M., Taha, A. E., Noreldin, A., El-Tarabily, K. A., & Abd El-Hack, M. E.
Affiliations: Zagazig University (EG)
Alexandria University (EG)
Damanhour University (EG)
Murdoch University (AU)
Corresponding author: Alagawany, Mahmoud
El-Tarabily, Khaled A.
ORCID: Alagawany, Mahmoud
Taha, Ayman E.
Noreldin, Ahmed
El-Tarabily, Khaled A.
Abd El-Hack, Mohamed E.
Venue: Aquaculture
Publisher: Elsevier BV
Published: 2021-09
Volume: 542
Pages: 736841
ISSN: 0044-8486 (ISSN-L)
DOI: 10.1016/j.aquaculture.2021.736841
OpenAlex: W3157582944
Cited by: 152
References: 172
Citations by year: 2026: 20 · 2025: 20 · 2024: 47 · 2023: 29 · 2022: 25 · 2021: 11
FWCI: 2.55
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Aquaculture (publishedVersion)
Murdoch University Research Portal (submittedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
Keywords: Spirulina, Chlorella, microalgae, fish nutrition, fish meal replacement, plant proteins, polyunsaturated fatty acids, fish growth promotion, immunostimulation, reproductive performance, Labeo rohita, Oreochromis niloticus, rainbow trout, heavy metal removal, wastewater treatment, aquaculture wastewater, feed additives

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nutritional applications of species of Spirulina and Chlorella in farmed fish: A review

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks