Role of the Blood–Brain Barrier in Multiple Sclerosis

Reactive Oxygen Species and the Central Nervous System

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Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

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Drug Transport across the Blood–Brain Barrier

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Mfsd2a is critical for the formation and function of the blood-brain barrier

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Nitric Oxide Production and Signaling in Inflammation

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Nitric oxide and redox mechanisms in the immune response

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Free Radical Pathways in CNS Injury

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Blood-Brain Barrier: From Physiology to Disease and Back

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Multiple sclerosis

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Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology

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The blood-brain barrier in aging and neurodegeneration

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Identification of tissue-specific cell death using methylation patterns of circulating DNA

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Macrophage polarization: an important role in inflammatory diseases

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Microglia–blood vessel interactions: a double-edged sword in brain pathologies

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A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

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Selenium, selenoproteins and neurodegenerative diseases

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Exercise as Medicine in Multiple Sclerosis—Time for a Paradigm Shift: Preventive, Symptomatic, and Disease-Modifying Aspects and Perspectives

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Leaky Gut, Leaky Brain?

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Brain and Retinal Pericytes: Origin, Function and Role

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WNT-β Catenin Signaling as a Potential Therapeutic Target for Neurodegenerative Diseases: Current Status and Future Perspective

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The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics

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Vascular Endothelial Cells: Heterogeneity and Targeting Approaches

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Pericytes regulate vascular immune homeostasis in the CNS

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Reviewing the Significance of Blood–Brain Barrier Disruption in Multiple Sclerosis Pathology and Treatment

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Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders

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Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis

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Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology

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Blood brain barrier: A review of its anatomy and physiology in health and disease

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Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

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Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders

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Breaking the Barrier: The Role of Proinflammatory Cytokines in BBB Dysfunction

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Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

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Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model

Shigemoto‐Mogami, Y., Hoshikawa, K., & Sato, K. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00494 · Cited by 118

Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders

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Therapeutic potential of curcumin for multiple sclerosis

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The action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis

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Blood–brain barrier and its function during inflammation and autoimmunity

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Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease pathology

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Efficacy of Melatonin on Serum Pro-inflammatory Cytokines and Oxidative Stress Markers in Relapsing Remitting Multiple Sclerosis

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TIMP1 preserves the blood–brain barrier through interacting with CD63/integrin 1 complex and regulating downstream FAK/RhoA signaling

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Kv1.3 Channel as a Key Therapeutic Target for Neuroinflammatory Diseases: State of the Art and Beyond

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Neuroinflammation: A Signature or a Cause of Epilepsy?

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A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches

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Sex differences in the blood–brain barrier and neurodegenerative diseases

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Brain drug delivery and neurodegenerative diseases: Polymeric PLGA-based nanoparticles as a forefront platform

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Astrocytes contribute to Aβ‐induced blood–brain barrier damage through activation of endothelial MMP 9

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S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis

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From Neurodevelopmental to Neurodegenerative Disorders: The Vascular Continuum

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Nanocarrier-mediated brain delivery of bioactives for treatment/prevention of neurodegenerative diseases

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Blood–Brain Barrier Breakdown in Neuroinflammation: Current In Vitro Models

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Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke

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Korean Red Ginseng and Ginsenoside-Rb1/-Rg1 Alleviate Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells and Upregulating Regulatory T Cells

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Exercise and Neuroinflammation in Health and Disease

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Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis

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Blood–Brain Barrier Disruption in Neuroimmunological Disease

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Neurofilament levels are associated with blood–brain barrier integrity, lymphocyte extravasation, and risk factors following the first demyelinating event in multiple sclerosis

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Lipid nanocapsules to enhance drug bioavailability to the central nervous system

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Promising Nanotechnology Approaches in Treatment of Autoimmune Diseases of Central Nervous System

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Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis

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The restorative role of annexin A1 at the blood–brain barrier

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Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders

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Protective associations of HDL with blood-brain barrier injury in multiple sclerosis patients

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Biosensors Integration in Blood–Brain Barrier-on-a-Chip: Emerging Platform for Monitoring Neurodegenerative Diseases

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Heterogeneous astrocytes: Active players in CNS

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IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier

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Exercise-induced changes in neurotrophic factors and markers of blood-brain barrier permeability are moderated by weight status in multiple sclerosis.

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Rituximab in Multiple Sclerosis: Are We Ready for Regulatory Approval?

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Immune Regulation of Antibody Access to Neuronal Tissues

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A Comprehensive View on MRI Techniques for Imaging Blood-Brain Barrier Integrity.

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Blood-brain barrier models: Rationale for selection

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The potential therapeutic effect of statins in multiple sclerosis: beneficial or detrimental effects

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A strocyte disruption of neurovascular communication is linked to cortical damage in an animal model of multiple sclerosis

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The interplay between T helper cells and brain barriers in the pathogenesis of multiple sclerosis

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Application of nanomedicine for crossing the blood–brain barrier: Theranostic opportunities in multiple sclerosis

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Regulatory T cell therapy for multiple sclerosis: Breaching (blood-brain) barriers

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Altered astrocytic function in experimental neuroinflammation and multiple sclerosis

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Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing–remitting multiple sclerosis

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A human-on-a-chip approach to tackling rare diseases

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Pericytes Across the Lifetime in the Central Nervous System

Bennett, H. C., & Kim, Y. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.627291 · Cited by 49

Barrier-on-a-Chip with a Modular Architecture and Integrated Sensors for Real-Time Measurement of Biological Barrier Function

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Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM

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Dietary Polyphenols as a Protection against Cognitive Decline: Evidence from Animal Experiments; Mechanisms and Limitations

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Implicating neuroinflammation in hippocampus, prefrontal cortex and amygdala with cognitive deficit: a narrative review

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Flavonoids, the compounds with anti-inflammatory and immunomodulatory properties, as promising tools in multiple sclerosis (MS) therapy: A systematic review of preclinical evidence

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miR-27a-3p regulates expression of intercellular junctions at the brain endothelium and controls the endothelial barrier permeability

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IL-21 and IL-21 receptor in the immunopathogenesis of multiple sclerosis

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Mfsd2a-based pharmacological strategies for drug delivery across the blood–brain barrier

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BDNF and Tau as Biomarkers of Severity in Multiple Sclerosis

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siRNA Therapeutics: Future Promise for Neurodegenerative Diseases

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Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis

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