The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression

On the origin of cancer cells

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Cancer genes and the pathways they control

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

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Glycolysis inhibition for anticancer treatment

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

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The multifaceted contributions of mitochondria to cellular metabolism

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How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

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Increased demand for NAD(+) relative to ATP drives aerobic glycolysis

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Cancer as a metabolic disease: implications for novel therapeutics

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Energy metabolism in health and diseases

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The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

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Interconnection between Metabolism and Cell Cycle in Cancer

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Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non‐transformed and cancer cells

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Mitochondrial Channels: Ion Fluxes and More

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An evolutionary perspective on the Crabtree effect

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The Warburg Effect 97 Years after Its Discovery

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Biology of glucose metabolization in cancer cells

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The Warburg effect and drug resistance

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The malate-aspartate shuttle (Borst cycle): how it started and developed into a major metabolic pathway

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SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration

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Cell energy metabolism: An update

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The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate

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Guidelines and recommendations on yeast cell death nomenclature

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Exosome-derived circTRPS1 promotes malignant phenotype and CD8+ T cell exhaustion in bladder cancer microenvironments

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Biotechnological production of ethanol: Biochemistry, processes and technologies

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‘Warburg effect’ controls tumor growth, bacterial, viral infections and immunity – Genetic deconstruction and therapeutic perspectives

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Constrained Allocation Flux Balance Analysis

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Mitochondrial Dysfunction in Diabetic Neuropathy: a Series of Unfortunate Metabolic Events

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2D Layered Double Hydroxide Nanoparticles: Recent Progress toward Preclinical/Clinical Nanomedicine

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Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect

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Benchmarking of commercially available CHO cell culture media for antibody production

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O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle

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Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis

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Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative

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Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes

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Polyphenols as mitochondria-targeted anticancer drugs

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Fructose 2,6-Bisphosphate in Cancer Cell Metabolism

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A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis

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Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells

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Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?

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MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis

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The Warburg Effect Explained: Integration of Enhanced Glycolysis with Heterogeneous Mitochondria to Promote Cancer Cell Proliferation

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The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?

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Osteoblast like MC3T3-E1 cells prefer glycolysis for ATP production but adipocyte like 3T3-L1 cells prefer oxidative phosphorylation

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Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

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Reversing the Warburg Effect as a Treatment for Glioblastoma

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Chromatin-remodeling links metabolic signaling to gene expression

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Kaempferol Can Reverse the 5-Fu Resistance of Colorectal Cancer Cells by Inhibiting PKM2-Mediated Glycolysis

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Impacts of chemical gradients on microbial community structure

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Are cultured human myotubes far from home?

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Glycolysis for Microbiome Generation

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A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels

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On the duration of the microbial lag phase

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Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells

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Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

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Press-pulse: a novel therapeutic strategy for the metabolic management of cancer

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Mitochondrial dysfunction in cancer chemoresistance

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Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death

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Evolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity)

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Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis

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The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources

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Toxicity of CuO Nanoparticles to Yeast Saccharomyces cerevisiae BY4741 Wild-Type and Its Nine Isogenic Single-Gene Deletion Mutants

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Energy metabolism in cancer cells: How to explain the Warburg and Crabtree effects?

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Absence of Complex I Is Associated with Diminished Respiratory Chain Function in European Mistletoe

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L-Methionase: A Therapeutic Enzyme to Treat Malignancies

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O -Linked β- N -Acetylglucosamine Transferase Directs Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension

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Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation

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Metabolic control of signalling pathways and metabolic auto‐regulation

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Neuronal control of astrocytic respiration through a variant of the Crabtree effect

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Value-added biotransformation of cellulosic sugars by engineered Saccharomyces cerevisiae

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The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons

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The pathways related to glutamine metabolism, glutamine inhibitors and their implication for improving the efficiency of chemotherapy in triple-negative breast cancer

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Sugar and Glycerol Transport in Saccharomyces cerevisiae

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Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol

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Selective Tumor Cell Inhibition Effect of Ni–Ti Layered Double Hydroxides Thin Films Driven by the Reversed pH Gradients of Tumor Cells

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LncRNA TUG1 affects cell viability by regulating glycolysis in osteosarcoma cells

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Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States

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Computational Strategies for a System-Level Understanding of Metabolism

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Protein O-GlcNAcylation in cardiovascular diseases

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Monitoring cytosolic H2O2 fluctuations arising from altered plasma membrane gradients or from mitochondrial activity

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miR-4458 suppresses glycolysis and lactate production by directly targeting hexokinase2 in colon cancer cells

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Xylose assimilation enhances the production of isobutanol in engineered Saccharomyces cerevisiae

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Tumor cell energy metabolism and its common features with yeast metabolism

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The Warburg Effect Explained: Integration of Enhanced Glycolysis with Heterogeneous Mitochondria to Promote Cancer Cell Proliferation

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Targeting glycolytic enzymes and mitochondria as novel cancer therapy

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Chicken or the egg: Warburg effect and mitochondrial dysfunction

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The Warburg Effect in Yeast: Repression of Mitochondrial Metabolism Is Not a Prerequisite to Promote Cell Proliferation

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