Cited by 186Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

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Lipids in Alzheimer’s disease: A century-old story

Foley, Paul·2010·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

DOI 10.1016/j.bbalip.2010.05.004

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Abstract

Three neuropathological features attracted the attention of Alzheimer in his examination of the brain of Auguste Deter: abnormal fibrillary structures, cortical depositions now termed "plaques," and glial proliferation, whereby he noted remarkable lipid granule accumulation in the glia. These features were also recorded by Perusini and Kraepelin, but by 1930 the lipoid deposits were no longer regarded by neuropathologists with great interest.

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Authors: Foley, P.
Affiliations: Neuroscience Research Australia (AU)
Corresponding author: Foley, Paul
Venue: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Publisher: Elsevier BV
Published: 2010-08
Volume: 1801
Issue: 8
Pages: 750-753
ISSN: 1388-1981 (ISSN-L)
DOI: 10.1016/j.bbalip.2010.05.004
OpenAlex: W2040912634
Cited by: 186
References: 12
Citations by year: 2026: 8 · 2025: 24 · 2024: 20 · 2023: 10 · 2022: 15 · 2021: 12 · 2020: 28 · 2019: 9 · 2018: 10 · 2017: 6 · 2016: 10 · 2015: 9 · 2014: 10 · 2013: 8 · 2012: 3
FWCI: 3.25
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: Alzheimer's disease, lipids, lipid granules, glial cell proliferation, amyloid plaques, neurofibrillary tangles, history of Alzheimer's disease, neuropathology
MeSH terms: Alzheimer Disease, Brain, Humans, Lipids, History, 20th Century, History, 21st Century, Lipid Metabolism

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Lipids in Alzheimer’s disease: A century-old story

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