The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Lipid droplet functions beyond energy storage
Open accessAbstract
Lipid droplets are cytoplasmic organelles that store neutral lipids and are critically important for energy metabolism. Their function in energy storage is firmly established and increasingly well characterized. However, emerging evidence indicates that lipid droplets also play important and diverse roles in the cellular handling of lipids and proteins that may not be directly related to energy homeostasis. Lipid handling roles of droplets include the storage of hydrophobic vitamin and signaling precursors, and the management of endoplasmic reticulum and oxidative stress. Roles of lipid droplets in protein handling encompass functions in the maturation, storage, and turnover of cellular and viral polypeptides. Other potential roles of lipid droplets may be connected with their intracellular motility and, in some cases, their nuclear localization. This diversity highlights that lipid droplets are very adaptable organelles, performing different functions in different biological contexts.
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Cites
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Lipid droplet biogenesis and functions in health and disease
Zadoorian, A., Du, X., & Yang, H. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00845-0 · Cited by 617
More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond Chemotaxis
Gschwandtner, M., Derler, R., & Midwood, K. S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02759 · Cited by 611
Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death
Danielli, M., Perne, L., Jarc Jovičić, E., & Petan, T. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1104725 · Cited by 180
Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation
Farmer, B., Kluemper, J., & Johnson, L. (2019) · Cells · doi:10.3390/cells8020182 · Cited by 164
Lipid Droplets Mediate Salt Stress Tolerance in Parachlorella kessleri 1
You, Z., Zhang, Q., Peng, Z., & Miao, X. (2019) · Plant Physiology · doi:10.1104/pp.19.00666 · Cited by 87
Metadata
- Authors
- Welte, M. A., & Gould, A. P.
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 1862
- Issue
- 10
- Pages
- 1260-1272
- ISSN
- 1388-1981 (ISSN-L)
- OpenAlex
- W2739293386
- Cited by
- 577
- References
- 12
- FWCI
- 17.06
- Type
- journal article
- Language
- en
- Open access
- green
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- Welte, M. A., & Gould, A. P. (2017). Lipid droplet functions beyond energy storage. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. https://doi.org/10.1016/j.bbalip.2017.07.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
