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Cited by 361

The DOI matches its Crossref record; 173 of the 173 references it cites were found in a registry or an index.

Role of S100 proteins in health and disease

Open access
Gonzalez, Laura L., Garrie, Karin, Turner, Mark D.·2020·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Abstract

The S100 family of proteins contains 25 known members that share a high degree of sequence and structural similarity. However, only a limited number of family members have been characterized in depth, and the roles of other members are likely undervalued. Their importance should not be underestimated however, as S100 family members function to regulate a diverse array of cellular processes including proliferation, differentiation, inflammation, migration and/or invasion, apoptosis, Ca2+ homeostasis, and energy metabolism. Here we detail S100 target protein interactions that underpin the mechanistic basis to their function, and discuss potential intervention strategies targeting S100 proteins in both preclinical and clinical situations.

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Metadata

Authors
Gonzalez, L. L., Garrie, K., & Turner, M. D.
Venue
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Publisher
Elsevier BV
Published
2020-06
Volume
1867
Issue
6
Pages
118677
ISSN
0167-4889 (ISSN-L)
OpenAlex
W3005706188
Cited by
361
References
173
FWCI
12.24
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Role of S100 proteins in health and disease. https://app.cochat.ai/papers/10.1016/j.bbamcr.2020.118677
The paper
Gonzalez, L. L., Garrie, K., & Turner, M. D. (2020). Role of S100 proteins in health and disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. https://doi.org/10.1016/j.bbamcr.2020.118677

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.