Biomarkers for epithelial-mesenchymal transitions

The basics of epithelial-mesenchymal transition

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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

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Fibroblasts in cancer

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Tumors: Wounds That Do Not Heal

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Complex networks orchestrate epithelial–mesenchymal transitions

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Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

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Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

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Epithelial-mesenchymal transition and its implications for fibrosis

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Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

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A molecular signature of metastasis in primary solid tumors

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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Molecular requirements for epithelial–mesenchymal transition during tumor progression

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

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Formation and function of the myofibroblast during tissue repair

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

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The Snail genes as inducers of cell movement and survival: implications in development and cancer

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Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

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BMP-7 counteracts TGF-β1–induced epithelial-to-mesenchymal transition and reverses chronic renal injury

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Direct regulation of TWIST by HIF-1α promotes metastasis

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Fibronectins: multifunctional modular glycoproteins.

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Alveolar epithelial cell mesenchymal transition develops <i>in vivo</i> during pulmonary fibrosis and is regulated by the extracellular matrix

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Diversity, topographic differentiation, and positional memory in human fibroblasts

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Identification and characterization of a fibroblast marker: FSP1.

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Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

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Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

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The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

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Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

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Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

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Different intermediate-sized filaments distinguished by immunofluorescence microscopy.

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Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

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Snail blocks the cell cycle and confers resistance to cell deathPreprint

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Fibroblasts Derive from Hepatocytes in Liver Fibrosis via Epithelial to Mesenchymal Transition

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Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells.

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Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

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The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it

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The Cellular Basis of Kidney Development

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A Wnt–Axin2–GSK3β cascade regulates Snail1 activity in breast cancer cells

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Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

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Mice lacking vimentin develop and reproduce without an obvious phenotype

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Mesenchyme Forkhead 1 ( FOXC2 ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

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FOXC2 Is a Winged Helix Gene that Counteracts Obesity, Hypertriglyceridemia, and Diet-Induced Insulin Resistance

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Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs

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Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

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Early role of Fsp1 in epithelial-mesenchymal transformation

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DIRECT EVIDENCE FOR A ROLE OF β‐CATENIN/LEF‐1 SIGNALING PATHWAY IN INDUCTION OF EMT

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Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

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Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma

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Murine forkhead/winged helix genesFoxc1(Mf1) andFoxc2(Mfh1) are required for the early organogenesis of the kidney and urinary tract

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Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

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Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

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Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

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β-Catenin: A Pivot between Cell Adhesion and Wnt Signalling

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Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family.Preprint

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RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

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Nuclear Overexpression of the Oncoprotein β-Catenin in Colorectal Cancer is Localized Predominantly at the Invasion Front

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Organization of fibroblasts in the heart

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Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily

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The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis.

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Regeneration or scarring: An immunologic perspective

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Laminin-5 With Transforming Growth Factor-β1 Induces Epithelial to Mesenchymal Transition in Hepatocellular Carcinoma

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Cooperation between Snail and LEF-1 Transcription Factors Is Essential for TGF-β1-induced Epithelial-Mesenchymal Transition

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Mesenchymal Stem Cells: Lineage, Plasticity, and Skeletal Therapeutic Potential

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Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers

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Kruppel-Like Factor 8 Induces Epithelial to Mesenchymal Transition and Epithelial Cell Invasion

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Renal Fibrosis

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Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

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HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer

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Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: A clinical and in vitro investigation

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EMT : Present and future in clinical oncology

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Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?

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Epithelial–mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease

Jolly, M. K., Ward, C., Eapen, M. S., Myers, S., Hällgren, O., Levine, H., & Sohal, S. S. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24541 · Cited by 252 · see citing works

The role of EMT and MET in cancer dissemination

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Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling

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Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease

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NF-kappaB: Two Sides of the Same Coin

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Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

Shaykhiev, R., Otaki, F. A., Bonsu, P., Dang, D. T., Teater, M. R., Strulovici‐Barel, Y., Salit, J., Harvey, B., & Crystal, R. G. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0500-x · Cited by 228 · see citing works

Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell–Cancer-Associated Fibroblast Interactions during Collective Invasion

Richardson, A. M., Havel, L. S., Koyen, A. E., Konen, J. M., Shupe, J. A., Wiles, W. G., Martin, W. D., Grossniklaus, H. E., Sica, G., Gilbert‐Ross, M., et al. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-1776 · Cited by 228 · see citing works

Epithelial to mesenchymal transition in head and neck squamous cell carcinoma

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Micro‐RNA signature of the epithelial–mesenchymal transition in endometrial carcinosarcoma

Castilla, M. Á., Moreno‐Bueno, G., Romero‐Pérez, L., de Vijver, K. K. V., Biscuola, M., López‐García, M. Á., Prat, J., Matías‐Guiu, X., Cano, A., Oliva, E., et al. (2010) · The Journal of Pathology · doi:10.1002/path.2802 · Cited by 224 · see citing works

TGF‐β regulates isoform switching of FGF receptors and epithelial–mesenchymal transition

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Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

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Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells

Kikuta, K., Masamune, A., Watanabe, T., Ariga, H., Itoh, H., Hamada, S., Satoh, K., Egawa, S., Unno, M., & Shimosegawa, T. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.11.040 · Cited by 224 · see citing works

Resolved

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Identification of miRs-143 and -145 that Is Associated with Bone Metastasis of Prostate Cancer and Involved in the Regulation of EMT

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Hedgehog Pathway Activation and Epithelial-to-Mesenchymal Transitions During Myofibroblastic Transformation of Rat Hepatic Cells in Culture and Cirrhosis

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Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution

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Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer

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Origin and functional heterogeneity of fibroblasts

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Tissue geometry patterns epithelial–mesenchymal transition via intercellular mechanotransduction

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Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling

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Small Molecule Mesengenic Induction of Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/Stromal Cells

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Plasticity of disseminating cancer cells in patients with epithelial malignancies

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Mesothelial cells in tissue repair and fibrosis

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Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype

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Platelets drive smooth muscle metaplasia and fibrogenesis in endometriosis through epithelial–mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation

Zhang, Q., Duan, J., Liu, X., & Guo, S.-W. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.03.015 · Cited by 211 · see citing works

Astrocytes, the rising stars of the glioblastoma microenvironment

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Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation

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Mitochondrial ROS and cancer drug resistance: Implications for therapy

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Epithelial‐to‐mesenchymal plasticity from development to disease: An introduction to the special issue

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Biomarkers of epithelial mesenchymal transition

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Epithelial–Mesenchymal Plasticity in Cancer: Transcriptional Regulation, Biomarker Challenges, and Emerging Therapeutic Opportunities

Shah, D., & Alavala, R. R. (2026) · Cell Biochemistry and Function · doi:10.1002/cbf.70271

Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries

Corallino, S., Malabarba, M. G., Zobel, M., Fiore, P. P. D., & Scita, G. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00045 · Cited by 54 · see citing works

Validity of Markers for Epithelial Cells and Mesenchymal Cells

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