The skin barrier in healthy and diseased state

The function of sterols in membranes

Demel, R. A., & De Kruyff, B. (1976) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(76)90008-3 · Cited by 1,341

Decreased Level of Ceramides in Stratum Corneum of Atopic Dermatitis: An Etiologic Factor in Atopic Dry Skin?

Imokawa, G., Abe, A., Jin, K., Higaki, Y., Kawashima, M., & Hidano, A. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470233 · Cited by 1,041

Physiology, Biochemistry, and Molecular Biology of the Skin

Shelley, W. B. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03490040129042 · Cited by 785

Structural and Lipid Biochemical Correlates of the Epidermal Permeability Barrier

ELIAS, P. M., & MENON, G. K. (1991) · Advances in Lipid Research · doi:10.1016/b978-0-12-024924-4.50005-5 · Cited by 678

Structural Investigations of Human Stratum Corneum by Small-Angle X-Ray Scattering

Bouwstra, J. A., Gooris, G. S., van der Spek, J. A., & Bras, W. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12492217 · Cited by 567

Ceramide and cholesterol composition of the skin of patients with atopic dermatitis

Di Nardo, P. W. (1998) · Acta Dermato-Venereologica · doi:10.1080/00015559850135788 · Cited by 483

Mutations of Keratinocyte Transglutaminase in Lamellar Ichthyosis

Huber, M., Rettler, I., Bernasconi, K., Frenk, E., Lavrijsen, S. P. M., Ponec, M., Bon, A., Lautenschlager, S., Schorderet, D. F., & Hohl, D. (1995) · Science · doi:10.1126/science.7824952 · Cited by 481

Ceramide composition of the psoriatic scale

Motta, S., Monti, M., Sesana, S., Caputo, R., Carelli, S., & Ghidoni, R. (1993) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(93)90135-n · Cited by 435

Presence of Intact Intercellular Lipid Lamellae in the Upper Layers of the Stratum Corneum

Madison, K. C., Swartzendruber, D. C., Wertz, P. W., & Downing, D. T. (1987) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470386 · Cited by 368

Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An x-ray diffraction study

White, S. H., Mirejovsky, D., & King, G. I. (1988) · Biochemistry · doi:10.1021/bi00410a031 · Cited by 355

Evidence That the Corneocyte Has a Chemically Bound Lipid Envelope

Swartzendruber, D. C., Wertz, P. W., Madison, K. C., & Downing, D. T. (1987) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470383 · Cited by 349

Molecular models of the Intercellular Lipid Lamellae in Mammalian Stratum Corneum

Swartzendruber, D. C., Wertz, P. W., Kitko, D. J., Madison, K. C., & Downing, D. T. (1989) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12276794 · Cited by 336

Role of Stratum Corneum Lipid Fluidity in Transdermal Drug Flux

Golden, G. M., McKie, J. E., & Potts, R. O. (1987) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600760108 · Cited by 323

Lipid and protein structures in the permeability barrier of mammalian epidermis.

Downing, D. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41520-2 · Cited by 315

Impaired sphingomyelinase activity and epidermal differentiation in atopic dermatitis

Jensen, J.-M., Fölster-Holst, R., Baranowsky, A., Schunck, M., Winoto-Morbach, S., Neumann, C., Schütze, S., & Proksch, E. (2004) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.22621.x · Cited by 309

Membrane Structures in Normal and Essential Fatty Acid-Deficient Stratum Corneum: Characterization by Ruthenium Tetroxide Staining and X-Ray Diffraction

Hou, S. Y. E., Mitra, A. K., White, S. H., Menon, G. K., Ghadially, R., & Elias, P. M. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12461361 · Cited by 290

Role of ceramide 1 in the molecular organization of the stratum corneum lipids

Bouwstra, J. A., Gooris, G. S., Dubbelaar, F. E. R., Weerheim, A. M., IJzerman, A. P., & Ponec, M. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34214-0 · Cited by 289

Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.

Holleran, W. M., Ginns, E. I., Menon, G. K., Grundmann, J. U., Fartasch, M., McKinney, C. E., Elias, P. M., & Sidransky, E. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117160 · Cited by 285

The Biochemistry and Function of Stratum Corneum Lipids

SCHURER, N. Y., & ELIAS, P. M. (1991) · Advances in Lipid Research · doi:10.1016/b978-0-12-024924-4.50006-7 · Cited by 272

Structure of human stratum corneum as a function of temperature and hydration: A wide-angle X-ray diffraction study

Bouwstra, J. A., Gooris, G. S., Vries, M. A. S.-D., van der Spek, J. A., & Bras, W. (1992) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(92)90158-x · Cited by 271

Evaluation of barrier creams: an in vitro technique on human skin.

Treffel, P., Gabard, B., & Juch, R. (1994) · Acta Dermato-Venereologica · doi:10.2340/000155557416 · Cited by 268

6-Hydroxy-4-sphingenine in human epidermal ceramides.

Robson, K. J., Stewart, M. E., Michelsen, S., Lazo, N. D., & Downing, D. T. (1994) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39952-1 · Cited by 263

Lipid composition of cultured human keratinocytes in relation to their differentiation

Ponec, M., Weerheim, A., Kempenaar, J., Mommaas, A. M., & Nugteren, D. H. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38476-5 · Cited by 255

Examination of Stratum Corneum Barrier Function In Vivo by Infrared Spectroscopy

Bommannan, D., Potts, R. O., & Guy, R. H. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12555503 · Cited by 237

A domain mosaic model of the skin barrier.

Forslind, B. (1994) · Acta Dermato-Venereologica · doi:10.2340/00015555741214 · Cited by 236

Deficiency of Epidermal Protein-Bound ω-Hydroxyceramides in Atopic Dermatitis

Macheleidt, O., Sandhoff, K., & Kaiser, H. W. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01833.x · Cited by 232

High-Expression of Sphingomyelin Deacylase is an Important Determinant of Ceramide Deficiency Leading to Barrier Disruption in Atopic Dermatitis1

Hara, J., Higuchi, K., Okamoto, R., Kawashima, M., & Imokawa, G. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00072.x · Cited by 229

Lateral packing of hydrocarbon chains

Abrahamsson, S., Dahlen, B., Löfgren, H., & Pascher, I. (1978) · Progress in the Chemistry of Fats and other Lipids · doi:10.1016/0079-6832(78)90039-3 · Cited by 228

Aberrant Lipid Organization in Stratum Corneum of Patients with Atopic Dermatitis and Lamellar Ichthyosis

Pilgram, G. S. K., Vissers, D. C. J., van der Meulen, H., Koerten, H. K., Pavel, S., Lavrijsen, S. P. M., & Bouwstra, J. A. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01455.x · Cited by 225

Ceramides Are Bound to Structural Proteins of the Human Foreskin Epidermal Cornified Cell Envelope

Marekov, L. N., & Steinert, P. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.28.17763 · Cited by 217

Phase behavior of isolated skin lipids

Bouwstra, J. A., Gooris, G. S., Cheng, K., Weerheim, A., Bras, W., & Ponec, M. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42010-3 · Cited by 216

New Acylceramide in Native and Reconstructed Epidermis

Ponec, M., Weerheim, A., Lankhorst, P., & Wertz, P. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12103.x · Cited by 212

Abnormal Expression of Sphingomyelin Acylase in Atopic Dermatitis: An Etiologic Factor for Ceramide Deficiency?

Murata, Y., Ogata, J., Higaki, Y., Kawashima, M., Yada, Y., Higuchi, K., Tsuchiya, T., Kawaminami, S., & Imokawa, G. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12348937 · Cited by 211

Role of Ceramides in Barrier Function of Healthy and Diseased Skin

Choi, M. J., & Maibach, H. I. (2005) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200506040-00002 · Cited by 210

Lipid organization in pig stratum corneum.

Bouwstra, J. A., Gooris, G. S., Bras, W., & Downing, D. T. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40054-9 · Cited by 208

Skin Barrier Structure and Function: The Single Gel Phase Model

Norlén, L. (2001) · Journal of Investigative Dermatology · doi:10.1038/jid.2001.1 · Cited by 206

Covalently Bound Lipids of Human Stratum Corneum

Wertz, P. W., Madison, K. C., & Downing, D. T. (1989) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep13071317 · Cited by 205

Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.

Elias, P. M., Williams, M. L., Maloney, M. E., Bonifas, J. A., Brown, B. E., Grayson, S., & Epstein, E. H. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111552 · Cited by 195

The Lipid Organisation in the Skin Barrier

A. Bouwstra, F. E. R. D. (2000) · Acta Dermato-Venereologica · doi:10.1080/000155500750042826 · Cited by 191

Molecular arrangements of sphingolipids. The monolayer behaviour of ceramides

Löfgren, H., & Pascher, I. (1977) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(77)90068-8 · Cited by 171

Phase Behavior of Stratum Corneum Lipid Mixtures Based on Human Ceramides: The Role of Natural and Synthetic Ceramide 1

Bouwstra, J. A., Gooris, G. S., Dubbelaar, F. E. R., & Ponec, M. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01706.x · Cited by 165

Electron Diffraction Provides New Information on Human Stratum Corneum Lipid Organization Studied in Relation to Depth and Temperature

Pilgram, G. S. K., Marjolein Engelsma-van Pelt, A., Koerten, H. K., & Bouwstra, J. A. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00706.x · Cited by 165

Glucosylceramides of pig epidermis: structure determination.

Wertz, P. W., & Downing, D. T. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37896-2 · Cited by 164

Freeze-fracture replication of cells of stratum corneum of human epidermis.

Breathnach, A. S., Goodman, T., Stolinski, C., & Gross, M. (1973) · Europe PMC (PubMed Central) · Cited by 163

Phase behavior of lipid mixtures based on human ceramides: coexistence of crystalline and liquid phases

Bouwstra, J. A., Gooris, G. S., Dubbelaar, F. E. R., & Ponec, M. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31502-9 · Cited by 158

Reduced Skin Barrier Function Parallels Abnormal Stratum Corneum Lipid Organization in Patients with Lamellar Ichthyosis

Lavrijsen, A. P. M., Bouwstra, J. A., Gooris, G. S., Weerheim, A. M., Boddé, H. E., & Ponec, M. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12323752 · Cited by 151

Oriented Structure in Human Stratum Corneum Revealed by X-Ray Diffraction

Garson, J. C., Doucet, J., Lévêque, J., & Tsoucaris, G. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12514716 · Cited by 149

New Aspects of the Skin Barrier Organization

Bouwstra, J. A., Pilgram, G. S. K., Gooris, G. S., Koerten, H. K., & Ponec, M. (2001) · Skin Pharmacology and Physiology · doi:10.1159/000056391 · Cited by 148

Skin lipids and epidermal differentiation in atopic dermatitis

Proksch, E., Jensen, J., & Elias, P. M. (2003) · Clinics in Dermatology · doi:10.1016/s0738-081x(02)00370-x · Cited by 148

Acylglucosylceramides of pig epidermis: structure determination

Wertz, P. W., & Downing, D. T. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37949-9 · Cited by 142

Barrier Characteristics of Different Human Skin Types Investigated with X-Ray Diffraction, Lipid Analysis, and Electron Microscopy Imaging

Schreiner, V., Pfeiffer, S., Lanzendörfer, G., Wenck, H., Diembeck, W., Gooris, G. S., Proksch, E., & Bouwstra, J. A. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00941.x · Cited by 141

Permeability of acetic acid across gel and liquid-crystalline lipid bilayers conforms to free-surface-area theory

Xiang, T., & Anderson, B. D. (1997) · Biophysical Journal · doi:10.1016/s0006-3495(97)78661-2 · Cited by 140

X-ray Diffraction Analysis of Isolated Skin Lipids: Reconstitution of Intercellular Lipid Domains

McIntosh, T. J., Stewart, M. E., & Downing, D. T. (1996) · Biochemistry · doi:10.1021/bi952762q · Cited by 139

Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation

Egberts, F., Heinrich, M., Jensen, J., Winoto‐Morbach, S., Pfeiffer, S., Wickel, M., Schunck, M., Steude, J., Säftig, P., Proksch, E., et al. (2004) · Journal of Cell Science · doi:10.1242/jcs.01075 · Cited by 130

Lamellar bodies as delivery systems of hydrolytic enzymes: Implications for normal and abnormal desquamation

Menon, G. K., Ghadially, R., Williams, M. L. K., et al. (1992) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1992.tb00675.x · Cited by 128

A Novel in Vitro Percutaneous Penetration Model: Evaluation of Barrier Properties with P-Aminobenzoic Acid and Two of Its Derivatives

de Jager, M., Groenink, W., Guivernau, R. B. I., Andersson, E., Angelova, N., Ponec, M., & Bouwstra, J. A. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9909-1 · Cited by 122

Disturbed extruding mechanism of lamellar bodies in dry non-eczematous skin of atopics

FARTASCH, M., Bassukas, I. D., & Diepgen, T. L. (1992) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1992.tb00118.x · Cited by 117

Visualization of diffusion pathways across the stratum corneum of native and in-vitro-reconstructed epidermis by confocal laser scanning microscopy

Simonetti, O., Kempenaar, J., Ponec, M., Hoogstraate, J. A., Bialik, W., Schrijvers, A. H. G. J., & Bodd�, H. E. (1995) · Archives of Dermatological Research · doi:10.1007/bf00373430 · Cited by 113

The role of ceramide composition in the lipid organisation of the skin barrier

Bouwstra, J. A., Dubbelaar, F. E. R., Gooris, G. S., et al. (1999) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(99)00057-7 · Cited by 112

Organization of Skin Stratum Corneum Extracellular Lamellae: Diffraction Evidence for Asymmetric Distribution of Cholesterol

McIntosh, T. J. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74597-4 · Cited by 112

A new 6-hydroxy-4-sphingenine-containing ceramide in human skin

Stewart, M. E., & Downing, D. T. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)33385-x · Cited by 112

Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior

de Jager, M. W., Gooris, G. S., Ponec, M., & Bouwstra, J. A. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500221-jlr200 · Cited by 110

Cholesterol Sulfate Inhibits Proteases that are Involved in Desquamation of Stratum Corneum

Sato, J., Denda, M., Nakanishi, J., Nomura, J., & Koyama, J. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00244.x · Cited by 109

pH, Cholesterol Sulfate, and Fatty Acids Affect the Stratum Corneum Lipid Organization

Bouwstra, J. A., Gooris, G. S., Dubbelaar, F. E. R., Ponec, M., & Weerheim, A. M. (1998) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.1998.17 · Cited by 109

Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers

ten Grotenhuis, E., DEMEL, R. A., Ponec, M., Boer, R., van Miltenburg, J. C., & Bouwstra, J. A. (1996) · Biophysical Journal · doi:10.1016/s0006-3495(96)79341-4 · Cited by 106

Epidermal barrier in disorders of the skin

Fartasch, M. (1997) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19970815)38:4<361::aid-jemt4>3.0.co;2-m · Cited by 102

Quantification of stratum corneum ceramides and lipid envelope ceramides in the hereditary ichthyoses

Paige, D. G., Fisher, N. M., & Harper, J. I. (1994) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1994.tb08452.x · Cited by 97

Epidermal Abnormalities May Distinguish Type 2 from Type 1 and Type 3 of Gaucher Disease

Sidransky, E., Fartasch, M., Lee, R. E., Metlay, L. A., Abella, S., Zimran, A., Gao, W., Elias, P. M., Ginns, E. I., & Holleran, W. M. (1996) · Pediatric Research · doi:10.1203/00006450-199601000-00020 · Cited by 95

Accumulation of protein‐bound epidermal glucosylceramides in β‐glucocerebrosidase deficient type 2 Gaucher mice

Doering, T., Proia, R. L., & Sandhoff, K. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00274-4 · Cited by 91

Molecular arrangements in sphingolipids. Thermotropic phase behaviour of tetracosanoylphytosphingosine

Dahlén, B., & Pascher, I. (1979) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(79)90082-3 · Cited by 87

Dithionite penetration through phospholipid bilayers as a measure of defects in lipid molecular packing

Langner, M., & Hui, S. W. (1993) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(93)90078-h · Cited by 86

Aspects Of Epidermal Ultrastructure

Breathnach, A. S. (1975) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12598018 · Cited by 85

Membrane Structural Abnormalities in the Stratum Corneum of the Autosomal Recessive Ichthyoses

Ghadially, R., Williams, M. L. K., Hou, S. Y. E., & Elias, P. M. (1992) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12614489 · Cited by 79

Effects of essential fatty acid deficiency on epidermal O-acylsphingolipids and transepidermal water loss in young pigs

Melton, J. L., Wertz, P. W., Swartzendruber, D. C., & Downing, D. T. (1987) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(87)90018-x · Cited by 77

Seasonal influences on stratum corneum ceramide 1 fatty acids and the influence of topical essential fatty acids

CONTI, A., Rogers, J. S., Verdejo, P., Harding, C. R., & Rawlings, A. V. (1996) · International Journal of Cosmetic Science · doi:10.1111/j.1467-2494.1996.tb00131.x · Cited by 77

Existence of a lipid gradient in the upper stratum corneum and its possible biological significance

Bonté, F., Saunois, A., Pinguet, P., & Meybeck, A. (1997) · Archives of Dermatological Research · doi:10.1007/s004030050158 · Cited by 77

Analysis of the Cornified Cell Envelope in Lamellar Ichthyosis

Hohl, D. (1993) · Archives of Dermatology · doi:10.1001/archderm.1993.01680260088013 · Cited by 71

Lipids Are Covalently Attached to Rigid Corneocyte Protein Envelopes Existing Predominantly as β-Sheets: A Solid-State Nuclear Magnetic Resonance Study

Lazo, N. D., MEINE, J. G., & Downing, D. T. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12318985 · Cited by 69

Lamellar Granule Extrusion and Stratum Corneum Intercellular Lamellae in Murine Keratinocyte Cultures

Madison, K. C., Swartzendruber, D. C., Wertz, P. W., & Downing, D. T. (1988) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12462065 · Cited by 68

Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis

Okamoto, R., Arikawa, J., Ishibashi, M., Kawashima, M., Takagi, Y., & Imokawa, G. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200225-jlr200 · Cited by 67

X-ray Diffraction Analysis of Stratum Corneum Membrane Couplets

Elias, P. M., Bonar, L. C., Grayson, S., et al. (1983) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12534362 · Cited by 60

Cholesterol and ergosterol superlattices in three-component liquid crystalline lipid bilayers as revealed by dehydroergosterol fluorescence

Liu, F., Sugár, I. P., & Chong, P. L. (1997) · Biophysical Journal · doi:10.1016/s0006-3495(97)78868-4 · Cited by 60

Abnormal Expression of the Novel Epidermal Enzyme, Glucosylceramide Deacylase, and the Accumulation of its Enzymatic Reaction Product, Glucosylsphingosine, in the Skin of Patients with Atopic Dermatitis

Ishibashi, M., Arikawa, J., Okamoto, R., et al. (2003) · Laboratory Investigation · doi:10.1097/01.lab.0000059931.66821.92 · Cited by 49

A Cross-Section Device To Improve Visualization of Fluorescent Probe Penetration into the Skin by Confocal Laser Scanning Microscopy

Kuijk-Meuwissen, M. E. M. J. V., Janssen, J., Cullander, C., Junginger, H. E., & Bouwstra, J. A. (1998) · Pharmaceutical Research · doi:10.1023/a:1011999509448 · Cited by 39

Studies of epidermal lipids using electron microscopy.

Swartzendruber, D. C. (1992) · PubMed · Cited by 35

Novel Mutations of the Transglutaminase 1 Gene in Lamellar Ichthyosis

Yang, J.-M., Ahn, K.-S., Cho, M.-O., Yoneda, K., Lee, C., Lee, J., Lee, E. S., Candi, E., Melino, G., Ahvazi, B., et al. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01429.x · Cited by 29

Lipid Organization of the Skin Barrier

Bouwstra, J. A. (2009) · Basic and clinical dermatology · doi:10.3109/9781420070958.002 · Cited by 26

Liposomes and skin: From drug delivery to model membranes

El Maghraby, G. M., Barry, B. W., & Williams, A. C. (2008) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2008.05.002 · Cited by 623

Cell death by cornification

Eckhart, L., Lippens, S., Tschachler, E., & Declercq, W. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.06.010 · Cited by 515

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

Janssens, M., van Smeden, J., Gooris, G. S., Bras, W., Portale, G., Caspers, P. J., Vreeken, R. J., Hankemeier, T., Kezic, S., Wolterbeek, R., et al. (2012) · Journal of Lipid Research · doi:10.1194/jlr.p030338 · Cited by 488

Permeation enhancers in transdermal drug delivery: benefits and limitations

Kováčik, A., Kopečná, M., & Vávrová, K. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2020.1713087 · Cited by 369

Recent Advances in Lipid-Based Vesicles and Particulate Carriers for Topical and Transdermal Application

Jain, S., Patel, N., Shah, M. K., Khatri, P., & Vora, N. (2017) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2016.10.001 · Cited by 283