Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

Catterall, W. A., Chandy, K. G., Clapham, D. E., Gutman, G. A., Hofmann, F., Harmar, A. J., Abernethy, D. R., & Spedding, M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.4.5 · Cited by 7,126 · see citing works

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

da Luz, A. C. D. D. S., Dias, G. P., Bevilaqua, M. C. D. N., Cocks, G. D., Gardino, P. F., Thuret, S., & Nardi, A. E. (2013) · Neuropsychobiology · doi:10.1159/000353269 · Cited by 4,012 · see citing works

Chemokines

Zlotnik, A., & Yoshie, O. (2000) · Immunity · doi:10.1016/s1074-7613(00)80165-x · Cited by 3,859 · see citing works

Chemokines — Chemotactic Cytokines That Mediate Inflammation

Luster, A. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380706 · Cited by 3,634 · see citing works

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

Zou, Y.-R., Kottmann, A. H., Kuroda, M., Taniuchi, I., & Littman, D. R. (1998) · Nature · doi:10.1038/31269 · Cited by 2,494 · see citing works

International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors

Murphy, P. M., Baggiolini, M., Charo, I. F., Hébert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., & Power, C. A. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01439-x · Cited by 1,817 · see citing works

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

Ma, Q., Jones, D., Borghesani, P. R., Segal, R. A., Nagasawa, T., Kishimoto, T., Bronson, R. T., & Springer, T. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9448 · Cited by 1,683 · see citing works

Chemokines and disease

Gerard, C., & Rollins, B. J. (2001) · Nature Immunology · doi:10.1038/84209 · Cited by 1,357 · see citing works

Long-Lasting Neurotrophin-Induced Enhancement of Synaptic Transmission in the Adult Hippocampus

Kang, H., & Schuman, E. M. (1995) · Science · doi:10.1126/science.7886457 · Cited by 1,354 · see citing works

Abnormalities in Monocyte Recruitment and Cytokine Expression in Monocyte Chemoattractant Protein 1–deficient Mice

Lu, B., RUTLEDGE, B. J., Gu, L., Fiorillo, J., Lukacs, N. W., Kunkel, S. L., North, R. J., Gerard, C. J., & Rollins, B. J. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.4.601 · Cited by 1,017 · see citing works

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

Gerlai, R. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)20020-7 · Cited by 881 · see citing works

Sickness behavior as a new target for drug development

Kent, S., Bluthé, R.-M., Kelley, K. W., & Dantzer, R. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90012-u · Cited by 863 · see citing works

Chemokines in pathology and medicine

Baggiolini, M. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00867.x · Cited by 710 · see citing works

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

Kuziel, W. A., Morgan, S. J., Dawson, T. C., Griffin, S., Smithies, O., Ley, K. F., & Maeda, N. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.22.12053 · Cited by 709 · see citing works

Requirement of Mip-1α for an Inflammatory Response to Viral Infection

Cook, D. N., Beck, M. A., Coffman, T. M., Kirby, S. L., Sheridan, J. F., Pragnell, L. B., & Smithies, O. (1995) · Science · doi:10.1126/science.7667639 · Cited by 616 · see citing works

Voluntary consumption of ethanol in 15 inbred mouse strains

Belknap, J. K., Crabbe, J. C., & Young, E. R. (1993) · Psychopharmacology · doi:10.1007/bf02244901 · Cited by 565 · see citing works

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases

Cartier, L., Hartley, O., Dubois‐Dauphin, M., & Krause, K. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.07.021 · Cited by 507 · see citing works

Ethanol consumption and resistance are inversely related to neuropeptide Y levels

Thiele, T. E., Marsh, D. J., Marie, L. S., Bernstein, I. L., & Palmiter, R. D. (1998) · Nature · doi:10.1038/24614 · Cited by 468 · see citing works

CONSEQUENCES OF ALCOHOL CONSUMPTION ON HOST DEFENCE

Szabó, G. (1999) · Alcohol and Alcoholism · doi:10.1093/alcalc/34.6.830 · Cited by 449 · see citing works

Regulation of oligodendrocyte development in the vertebrate CNS.

Miller, R. (2002) · Progress in neurobiology · doi:10.1016/s0301-0082(02)00058-8 · Cited by 426 · see citing works

Chemokines

Laing, K. J. (2003) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2003.09.006 · Cited by 418 · see citing works

The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)

Mahad, D., & Ransohoff, R. M. (2002) · Seminars in Immunology · doi:10.1016/s1044-5323(02)00125-2 · Cited by 412 · see citing works

CXC chemokines: the regulatory link between inflammation and angiogenesis

Romagnani, P., Lasagni, L., Annunziato, F., Serio, M., & Romagnani, S. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.02.006 · Cited by 410 · see citing works

The chemokine SDF1 regulates migration of dentate granule cells

Bagri, A., Gurney, T. A., He, X., Zou, Y.-R., Littman, D. R., Tessier‐Lavigne, M., & Pleasure, S. J. (2002) · Development · doi:10.1242/dev.129.18.4249 · Cited by 387 · see citing works

Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex

Lewohl, J. M., Wang, L., Miles, M. F., Zhang, L., Dodd, P. R., & Harris, R. A. (2000) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2000.tb01993.x · Cited by 379 · see citing works

Chemokine receptors

Horuk, R. (2001) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(01)00014-4 · Cited by 348 · see citing works

Chemokines in the CNS: plurifunctional mediators in diverse states

Asensio, V. C., & Campbell, I. L. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01453-8 · Cited by 346 · see citing works

Characterization of chemokines and their receptors in the central nervous system: physiopathological implications

Bajetto, A., Bonavia, R., Barbero, S., & Schettini, G. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01091.x · Cited by 318 · see citing works

Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics

Mayfield, R. D., Lewohl, J. M., Dodd, P. R., Herlihy, A. H., Liu, J., & Harris, R. A. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00860.x · Cited by 312 · see citing works

Increased plasma interleukin-8 concentrations in alcoholic hepatitis

Hill, D. B., Marsano, L. S., & McClain, C. J. (1993) · Hepatology · doi:10.1002/hep.1840180316 · Cited by 303 · see citing works

Cytokines and Sickness Behavior

Dantzer, R., Bluthé, R.-M., Layé, S., Bret-Dibat, J. L., Parnet, P., & KELLEY, K. W. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09597.x · Cited by 303 · see citing works

The Alcohol Hangover

Wiese, J. G., Shlipak, M. G., & Browner, W. S. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-132-11-200006060-00008 · Cited by 285 · see citing works

Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine

Andres, P. G., Beck, P. L., Mizoguchi, E., Mizoguchi, A., Bhan, A. K., Dawson, T. C., Kuziel, W. A., Maeda, N., MacDermott, R. P., Podolsky, D. K., et al. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.12.6303 · Cited by 255 · see citing works

Molecular Basis of Sickness Behavior^a

DANTZER, R., BLUTHÉ, R., GHEUSI, G., CREMONA, S., LAYÉ, S., PARNET, P., & KELLEY, K. W. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb08321.x · Cited by 249 · see citing works

Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons

Zhu, Y., Yu, T., Zhang, X.-C., Nagasawa, T., Wu, J. Y., & Rao, Y. (2002) · Nature Neuroscience · doi:10.1038/nn881 · Cited by 235 · see citing works

Recent Insights into the Role of the Innate Immune System in the Development of Alcoholic Liver Disease

Nagy, L. E. (2003) · Experimental Biology and Medicine · doi:10.1177/153537020322800803 · Cited by 227 · see citing works

Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis.

Karpus, W. J., & Ransohoff, R. M. (1998) · PubMed · Cited by 224 · see citing works

Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin

Maier, S. F., Wiertelak, E. P., Martin, D., & Watkins, L. R. (1993) · Brain Research · doi:10.1016/0006-8993(93)91446-y · Cited by 210 · see citing works

Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons

Coughlan, C. M., McManus, C. M., Sharron, M. P., Gao, Z., Murphy, D., Jaffer, S., Choe, W., Chen, W., Hesselgesser, J., Gaylord, H., et al. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00024-5 · Cited by 202 · see citing works

Astrocytes express functional chemokine receptors

Dorf, M. E., Berman, M. A., Tanabe, S., Heesen, M. A., & Luo, Y. (2000) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(00)00371-4 · Cited by 193 · see citing works

Stromal cell‐derived factor‐1α induces astrocyte proliferation through the activation of extracellular signal‐regulated kinases 1/2 pathway

Bajetto, A., Barbero, S., Bonavia, R., Piccioli, P., Pirani, P., Florio, T., & Schettini, G. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00350.x · Cited by 186 · see citing works

Relationship of Alcohol Intake With Inflammatory Markers and Plasminogen Activator Inhibitior-1 in Well-Functioning Older Adults: The Health, Aging, and Body Composition Study

Volpato, S., Pahor, M., Ferrucci, L., Simonsick, E. M., Guralnik, J. M., Kritchevsky, S. B., Fellin, R., & Harris, T. B. (2004) · Circulation · doi:10.1161/01.cir.0000109503.13955.00 · Cited by 176 · see citing works

Chronic Alcohol Intoxication Induces Hepatic Injury Through Enhanced Macrophage Inflammatory Protein–2 Production and Intercellular Adhesion Molecule–1 Expression in the Liver

Bautista, A. P., Jr. (1997) · Hepatology · doi:10.1002/hep.510250214 · Cited by 174 · see citing works

Fast actions of neurotrophic factors

Berninger, B., & Poo, M.-M. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80115-2 · Cited by 173 · see citing works

CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice

Kuziel, W. A., Dawson, T. C., Quinones, M. P., Garavito, É., Chenaux, G., Ahuja, S. S., Reddick, R. L., & Maeda, N. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(02)00382-9 · Cited by 164 · see citing works

High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption

Metten, P., Phillips, T. J., Crabbe, J. C., Tarantino, L. M., McClearn, G. E., Plomin, R. J., Erwin, V. G., & Belknap, J. K. (1998) · Mammalian Genome · doi:10.1007/s003359900911 · Cited by 158 · see citing works

Differential signalling of the chemokine receptor CXCR4 by stromal cell‐derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes

Lazarini, F., Casanova, P., Tham, T. N., Clercq, E. D., Arenzana‐Seisdedos, F., Baleux, F., & Dubois-Dalcq, M. E. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00894.x · Cited by 157 · see citing works

Differential Roles of CC Chemokine Ligand 2/Monocyte Chemotactic Protein-1 and CCR2 in the Development of T1 Immunity

Traynor, T. R., Herring, A. C., Dorf, M. E., Kuziel, W. A., Toews, G. B., & Huffnagle, G. B. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.9.4659 · Cited by 154 · see citing works

Complications associated with genetic background effects in research using knockout mice

Phillips, T. J., Hen, R., & Crabbe, J. C. (1999) · Psychopharmacology · doi:10.1007/s002130051128 · Cited by 154 · see citing works

CXC chemokines interleukin-8 (IL-8) and growth-related gene product α (GROα) modulate Purkinje neuron activity in mouse cerebellum

Giovannelli, A., Limatola, C., Ragozzino, D., Mileo, A. M., Ruggieri, A., Ciotti, M. T., Mercanti, D., Santoni, A., & Eusebi, F. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00192-1 · Cited by 150 · see citing works

Enhanced Pulmonary Allergic Responses to Aspergillus in CCR2−/− Mice

Blease, K., Mehrad, B., Standiford, T. J., Lukacs, N. W., Gosling, J., Boring, L. F., Charo, I. F., Kunkel, S. L., & Hogaboam, C. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.5.2603 · Cited by 145 · see citing works

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

Turner, L., Ward, S. G., & Westwick, J. K. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.5.2437 · Cited by 145 · see citing works

Short-Term Selective Breeding as a Tool for QTL Mapping: Ethanol Preference Drinking in Mice

Belknap, J. K., Richards, S. P., O’Toole, L. A., Helms, M. L., & Phillips, T. J. (1997) · Behavior Genetics · doi:10.1023/a:1025615409383 · Cited by 142 · see citing works

Pharmacologic and Behavioral Responses of Inbred C57BL/6J and Strain 129/SvJ Mouse Lines

Homanics, G. E., Quinlan, J. J., & Firestone, L. L. (1999) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(98)00232-9 · Cited by 134 · see citing works

Ethanol‐Induced Conditioned Taste Aversion in BXD Recombinant Inbred Mice

Risinger, F. O., & Cunningham, C. L. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03904.x · Cited by 127 · see citing works

Confirmation of Quantitative Trait Loci for Alcohol Preference in Mice

Tarantino, L. M., McClearn, G. E., Rodriguez, L. A., & Plomin, R. J. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03707.x · Cited by 125 · see citing works

Potassium Channels as Targets for Ethanol: Studies of G-Protein-Coupled Inwardly Rectifying Potassium Channel 2 (GIRK2) Null Mutant Mice

Blednov, Y. A., Stoffel, M., Chang, S., & Harris, R. A. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29410-6 · Cited by 122 · see citing works

Chronic Ethanol Consumption Induces the Production of Tumor Necrosis Factor‐α and Related Cytokines in Liver and Adipose Tissue

Lin, H., Yang, S., Zeldin, G. A., & Diehl, A. M. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb04008.x · Cited by 120 · see citing works

Expression Profiling of Neural Cells Reveals Specific Patterns of Ethanol-Responsive Gene Expression

Thibault-Carpentier, C., Lai, C., Wilke, N., Duong, B. H., Olive, M. F., Rahman, S., Dong, H., Hodge, C. W., Lockhart, D. J., & Miles, M. F. (2000) · Molecular Pharmacology · doi:10.1124/mol.58.6.1593 · Cited by 117 · see citing works

Chemokine levels in human liver homogenates: Associations between GRO alpha and histopathological evidence of alcoholic hepatitis

Maltby, J. (1996) · Hepatology · doi:10.1053/jhep.1996.v24.pm0008903391 · Cited by 116 · see citing works

Genes on mouse Chromosomes 2 and 9 determine variation in ethanol consumption

Phillips, T. J. (1998) · Mammalian Genome · doi:10.1007/s003359900903 · Cited by 108 · see citing works

Gene-targeting studies: new methods, old problems

Crusio, W. E. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)20023-2 · Cited by 107 · see citing works

Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges.

Trebst, C., & Ransohoff, R. M. (2001) · PubMed · doi:10.1001/archneur.58.12.1975 · Cited by 106 · see citing works

Chemokines in the brain: neuroimmunology and beyond

Biber, K. P. H. (2002) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(01)00122-9 · Cited by 104 · see citing works

Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1α in alcoholic liver disease

Fisher, N. C., Neil, D., Williams, A., & Adams, D. (1999) · Gut · doi:10.1136/gut.45.3.416 · Cited by 103 · see citing works

Ethanol-induced conditioned taste aversion in 15 inbred mouse strains.

Broadbent, J., Muccino, K. J., & Cunningham, C. L. (2002) · Behavioral Neuroscience · doi:10.1037/0735-7044.116.1.138 · Cited by 102 · see citing works

Chemokine-Chemokine Receptor Network in Immune Cell Trafficking

Kim, C. H. (2004) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568008043339712 · Cited by 95 · see citing works

Chemokines and Alzheimer's disease

Streit, W. (2001) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00290-1 · Cited by 94 · see citing works

Nuclear Factor-κB Activation by the CXC Chemokine Melanoma Growth-stimulatory Activity/Growth-regulated Protein Involves the MEKK1/p38 Mitogen-activated Protein Kinase Pathway

Wang, D., & Richmond, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006115200 · Cited by 93 · see citing works

Effects of alcohol hangover on cytokine production in healthy subjects

Kim, D., Kim, W. K., Yoon, S. J., Choi, B., Kim, J. S., Go, H. J., Kim, Y., & Jeong, J. (2003) · Alcohol · doi:10.1016/j.alcohol.2003.09.003 · Cited by 91 · see citing works

Reduction of exploratory behavior by intraperitoneal injection of interleukin-1 involves brain corticotropin-releasing factor

Dunn, A. J., Antoon, M., & Chapman, Y. (1991) · Brain Research Bulletin · doi:10.1016/0361-9230(91)90092-x · Cited by 89 · see citing works

Diverse regulation of NF-κB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver

Romics, L., Kodys, K., Dolganiuc, A., Graham, L. S., Velayudham, A., Mandrekar, P., & Szabó, G. (2004) · Hepatology · doi:10.1002/hep.20304 · Cited by 87 · see citing works

Mast Cell Cytokine and Chemokine Responses to Bacterial and Viral Infection

Marshall, J. S., King, C. A., & McCurdy, J. D. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033392413 · Cited by 81 · see citing works

Developmental expression of monocyte chemoattractant protein-1 in the human cerebellum and brainstem

Meng, S. Z., Oka, A., & Takashima, S. (1999) · Brain and Development · doi:10.1016/s0387-7604(98)00065-5 · Cited by 80 · see citing works

Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice

Yang, R., Han, X., Delude, R. L., & Fink, M. P. (2003) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(03)00138-0 · Cited by 76 · see citing works

Modulation of the neurotransmitter release in rat cerebellar neurons by GROβ

Ragozzino, D., Giovannelli, A., Mileo, A. M., Limatola, C., Santoni, A., & Eusebi, F. (1998) · Neuroreport · doi:10.1097/00001756-199811160-00011 · Cited by 76 · see citing works

Involvement of chemokines in pain

Boddeke, E. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01311-5 · Cited by 74 · see citing works

Ethanol Tolerance and Withdrawal Responses in GABAA Receptor Alpha 6 Subunit Null Allele Mice and in Inbred C57BL/6J and Strain 129/SvJ Mice

Homanics, G. E., Le, N. Q., Kist, F., Mihalek, R., Hart, A. R., & Quinlan, J. J. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03647.x · Cited by 71 · see citing works

Analysis of G-protein-coupled receptor dimerization following chemokine signaling

Mellado, M., Martínez‐A, C., & Rodrı́guez-Frade, J. M. (2002) · Methods · doi:10.1016/s1046-2023(02)00093-2 · Cited by 67 · see citing works

Chronic Ethanol Consumption Enhances Interleukin‐1‐Mediated Signal Transduction in Rat Liver and in Cultured Hepatocytes

Vallés, S. L., Blanco, A. M. A., Azorı́n, I., Guasch, R. M., Pascual, M., Gómez-Lechón, M. J., Renau‐Piqueras, J., & Guerri, C. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000099261.87880.21 · Cited by 64 · see citing works

Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease

Bautista, A. P. (2000) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.2000.02174.x · Cited by 62 · see citing works

ALCOHOL INTAKE, TUMOUR NECROSIS FACTOR-alpha, LEPTIN AND CRAVING: FACTORS OF A POSSIBLY VICIOUS CIRCLE?

Kiefer, F. (2002) · Alcohol and Alcoholism · doi:10.1093/alcalc/37.4.401 · Cited by 44 · see citing works

Reciprocal Congenics Defining Individual Quantitative Trait Loci for Sedative/Hypnotic Sensitivity to Ethanol

Bennett, B., Beeson, M., Gordon, L., & Johnson, T. E. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02519.x · Cited by 43 · see citing works

Chemokine blockade: a new era in the treatment of rheumatoid arthritis?

Haringman, J. J., & Tak, P. P. (2004) · Arthritis Research · doi:10.1186/ar1172 · Cited by 35 · see citing works

Limited importance of a learned aversion in the hypophagic effect of interleukin-1β

Bauer, C., Weingarten, S., Senn, M., & Langhans, W. (1995) · Physiology & Behavior · doi:10.1016/0031-9384(94)00379-j · Cited by 27 · see citing works

The Production of Tumor Necrosis Factor‐α by Macrophages in Rats With Acute Alcohol Loading

Kitazawa, T., Nakatani, Y., Fujimoto, M., Tamura, N., Uemura, M., & Fukui, H. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000078611.55696.f0 · Cited by 26 · see citing works

Alcohol, But Not Lipopolysaccharide-Induced Liver Apoptosis Involves Changes in Intracellular Compartmentalization of Apoptotic Regulators

Deaciuc, I. V., D'Souza, N. B., Burikhanov, R., Nasser, M. S., Voskresensky, I. V., de Villiers, W. J. S., & McClain, C. J. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2004.tb02981.x · Cited by 19 · see citing works

Effects of peripheral administration of recombinant human Interleukin-1 beta on feeding behavior of the rat

Shimomura, Y., Shimizu, H., Takahashi, M., Uehara, Y., Negishi, M., Sato, N., Inukai, T., Kobayashi, I., & KOBAYASHI, S. (1990) · Life Sciences · doi:10.1016/0024-3205(90)90148-k · Cited by 19 · see citing works

HIV-1 Infection and Chemokine Receptor Modulation

Ruibal-Ares, B., Belmonte, L., Baré, P., Parodi, C. M., Massud, I., & de Bracco, M. M. E. (2004) · Current HIV Research · doi:10.2174/1570162043484997 · Cited by 19 · see citing works

Antiviral potential of chemokines

Mahalingam, S., Clark, K. P., MATTHAEI, K. I., & Foster, P. S. (2001) · BioEssays · doi:10.1002/bies.1061 · Cited by 15 · see citing works

Impulsivity, frontal lobes and risk for addiction

Crews, F. T., & Boettiger, C. A. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.04.018 · Cited by 679 · see citing works

Increased MCP-1 and microglia in various regions of the human alcoholic brain

He, J., & Crews, F. T. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.11.017 · Cited by 516 · see citing works

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis

Mulligan, M. K., Ponomarev, I., HITZEMANN, R. J., Belknap, J. K., Tabakoff, B., Harris, R. A., Crabbe, J. C., Blednov, Y. A., Grahame, N. J., Phillips, T. J., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510188103 · Cited by 347 · see citing works

The role of neuroimmune signaling in alcoholism

Crews, F. T., Lawrimore, C. J., Walter, T. J., & Coleman, L. G. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.01.031 · Cited by 321 · see citing works

Induction of innate immune genes in brain create the neurobiology of addiction

Crews, F. T., Zou, J., & Qin, L. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.03.003 · Cited by 313 · see citing works

Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies

Blednov, Y. A., Ponomarev, I., Geil, C., Bergeson, S., Koob, G. F., & Harris, R. A. (2012) · Addiction Biology · doi:10.1111/j.1369-1600.2010.00284.x · Cited by 251 · see citing works

Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice

Blednov, Y. A., Benavidez, J. M., Geil, C., Perra, S., Morikawa, H., & Harris, R. A. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.01.008 · Cited by 241 · see citing works

Mechanisms of neuroimmune gene induction in alcoholism

Crews, F. T., & Vetreno, R. P. (2016) · Psychopharmacology · doi:10.1007/s00213-015-3906-1 · Cited by 232 · see citing works

Neuroimmune signaling in alcohol use disorder

Erickson, E. K., Grantham, E. K., Warden, A. S., & Harris, R. A. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.12.007 · Cited by 224 · see citing works

Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence

Coller, J. K., & Hutchinson, M. R. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.01.008 · Cited by 186 · see citing works

Impact of the Innate Immune Response in the Actions of Ethanol on the Central Nervous System

Montesinos, J., Alfonso‐Loeches, S., & Guerri, C. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13208 · Cited by 184 · see citing works

The link between inflammation, bugs, the intestine and the brain in alcohol dependence

Leclercq, S., de Timary, P., Delzenne, N. M., & Stärkel, P. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.15 · Cited by 174 · see citing works

Neuroimmune Mechanisms of Alcohol and Drug Addiction

Cui, C., Shurtleff, D., & Harris, R. A. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801284-0.00001-4 · Cited by 163 · see citing works

Induction of Innate Immune Gene Expression Cascades in Brain Slice Cultures by Ethanol: Key Role of NF‐κB and Proinflammatory Cytokines

Zou, J., & Crews, F. T. (2010) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01150.x · Cited by 158 · see citing works

Toll-like receptor signaling and stages of addiction

Crews, F. T., Walter, T. J., Coleman, L. G., & Vetreno, R. P. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4560-6 · Cited by 159 · see citing works

Genetic studies of alcohol dependence in the context of the addiction cycle

Reilly, M. T., Noronha, A., Goldman, D. A., & Koob, G. F. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.01.017 · Cited by 155 · see citing works

Minocycline reduces ethanol drinking

Agrawal, R. G., Hewetson, A., George, C. M., Syapin, P. J., & Bergeson, S. E. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.03.002 · Cited by 142 · see citing works

Involvement of TLR4 in the long-term epigenetic changes, rewarding and anxiety effects induced by intermittent ethanol treatment in adolescence

Montesinos, J., Pascual, M., Rodríguez‐Arias, M., Miñarro, J., & Guerri, C. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.12.006 · Cited by 141 · see citing works

Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking

Vetreno, R. P., Qin, L., & Crews, F. T. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.07.002 · Cited by 132 · see citing works

Effects of Ethanol on Immune Response in the Brain: Region-Specific Changes in Adolescent Versus Adult Mice

Kane, C. J. M., Phelan, K. D., Douglas, J. C., Wagoner, G., Johnson, J. W., Xu, J., Phelan, P. S., & Drew, P. D. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12244 · Cited by 131 · see citing works

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

Lowe, P., Morel, C., Ambade, A., Iracheta‐Vellve, A., Kwiatkowski, E. R., Satishchandran, A., Fűri, I., Cho, Y., Gyöngyösi, B., Catalano, D. E., et al. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01972-5 · Cited by 114 · see citing works

Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption

Bell, R. L., Kimpel, M. W., McClintick, J. N., Strother, W. N., Carr, L. G., Liang, T., Rodd, Z. A., Mayfield, R. D., Edenberg, H. J., & McBride, W. J. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.07.019 · Cited by 112 · see citing works

HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions

Persidsky, Y., Ho, W., Ramirez, S. H., Potula, R., Abood, M. E., Unterwald, E. M., & Tuma, R. F. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.03.001 · Cited by 106 · see citing works

Neuroimmune Pathways in Alcohol Consumption: Evidence from Behavioral and Genetic Studies in Rodents and Humans

Robinson, G., Most, D., Ferguson, L. B., Mayfield, J., Harris, R. A., & Blednov, Y. A. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801284-0.00002-6 · Cited by 96 · see citing works

Increased expression of M1 and M2 phenotypic markers in isolated microglia after four-day binge alcohol exposure in male rats

Peng, H., Geil, C., Chen, K. Y., McClain, J. A., & Nixon, K. (2017) · Alcohol · doi:10.1016/j.alcohol.2017.02.175 · Cited by 95 · see citing works

Innate Immune Signaling and Alcohol Use Disorders

Coleman, L. G., & Crews, F. T. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_92 · Cited by 90 · see citing works

Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity

Henriques, J. F., Portugal, C. C., Canedo, T., Relvas, J. B., Summavielle, T., & Socodato, R. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2017.11.002 · Cited by 89 · see citing works

Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure

Doremus‐Fitzwater, T. L., Gano, A., Paniccia, J. E., & Terrence Deak, B. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.02.032 · Cited by 88 · see citing works

Intoxication‐ and Withdrawal‐Dependent Expression of Central and Peripheral Cytokines Following Initial Ethanol Exposure

Doremus‐Fitzwater, T. L., Buck, H. M., Bordner, K. A., Richey, L., Jones, M. E., & Terrence Deak, B. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12481 · Cited by 85 · see citing works

Fetal Alcohol Spectrum Disorders and Neuroimmune Changes

Drew, P. D., & Kane, C. J. M. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801284-0.00003-8 · Cited by 78 · see citing works

Potential of Glial Cell Modulators in the Management of Substance Use Disorders

Jones, J. D. (2020) · CNS Drugs · doi:10.1007/s40263-020-00721-9 · Cited by 78 · see citing works

Inhibiting the TLR4‐MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol‐induced sedation and motor impairment in mice

Wu, Y. H., Lousberg, E. L., Moldenhauer, L. M., Hayball, J. D., Coller, J. K., Rice, K. C., Watkins, L. R., Somogyi, A. A., & Hutchinson, M. R. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01572.x · Cited by 76 · see citing works

Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice

Blednov, Y. A., Benavidez, J. M., Black, M., & Harris, R. A. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00129 · Cited by 75 · see citing works

Ethanol, TLR 3, and TLR 4 Agonists Have Unique Innate Immune Responses in Neuron‐Like SH ‐ SY 5Y and Microglia‐Like BV 2

Lawrimore, C. J., & Crews, F. T. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13368 · Cited by 73 · see citing works

Role of the innate immune system in the neuropathological consequences induced by adolescent binge drinking

Pascual, M., Montesinos, J., & Guerri, C. (2018) · Journal of Neuroscience Research · doi:10.1002/jnr.24203 · Cited by 71 · see citing works

Current hypotheses on the mechanisms of alcoholism

Vetreno, R. P., & Crews, F. T. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-62619-6.00027-6 · Cited by 71 · see citing works

Role of MCP-1 and CCR2 in alcohol neurotoxicity

Zhang, K., & Luo, J. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.11.030 · Cited by 68 · see citing works

Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats

Ehrlich, D., Pirchl, M., & Humpel, C. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2011.12.054 · Cited by 65 · see citing works

Ethanol and Cytokines in the Central Nervous System

Roberto, M., Patel, R. R., & Bajo, M. (2017) · Handbook of experimental pharmacology · doi:10.1007/164_2017_77 · Cited by 71 · see citing works

Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice

Warden, A. S., Azzam, M. M., DaCosta, A., Mason, S., Blednov, Y. A., Messing, R. O., Mayfield, R. D., & Harris, R. A. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.12.004 · Cited by 61 · see citing works

Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure

Rivera, P., Fernández‐Arjona, M. D. M., Silva‐Peña, D., Blanco, E., Vargas, A., López-Ávalos, M. D., Grondona, J. M., Serrano, A., Pavón, F. J., de Fonseca, F. R., et al. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.08.005 · Cited by 51 · see citing works

Chronic inflammatory pain drives alcohol drinking in a sex-dependent manner for C57BL/6J mice

Yu, W., Hwa, L. S., Makhijani, V. H., Besheer, J., & Kash, T. L. (2018) · Alcohol · doi:10.1016/j.alcohol.2018.10.002 · Cited by 55 · see citing works

Genes and Alcohol Consumption

Mayfield, J., Arends, M. A., Harris, R. A., & Blednov, Y. A. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.02.014 · Cited by 54 · see citing works

Addiction, Adolescence, and Innate Immune Gene Induction

Crews, F. T., & Vetreno, R. P. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00019 · Cited by 52 · see citing works

Immune function genes, genetics, and the neurobiology of addiction

Crews, F. T. (2012) · Alcohol research · doi:10.35946/arcr.v34.3.11 · Cited by 52 · see citing works

Inflammatory responses to alcohol in the CNS: nuclear receptors as potential therapeutics for alcohol-induced neuropathologies

Kane, C. J. M., & Drew, P. D. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.3mr0416-171r · Cited by 52 · see citing works

Increased Toll‐like Receptor‐MyD88‐NFκB‐Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder

Vetreno, R. P., Qin, L., Coleman, L. G., & Crews, F. T. (2021) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14669 · Cited by 50 · see citing works

Microglia depletion and alcohol: Transcriptome and behavioral profiles

Warden, A. S., Triplett, T., Lyu, A., Grantham, E. K., Azzam, M. M., DaCosta, A., Mason, S., Blednov, Y. A., Ehrlich, L. I. R., Mayfield, R. D., et al. (2020) · Addiction Biology · doi:10.1111/adb.12889 · Cited by 50 · see citing works

Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer’s disease

Kurata, T., Miyazaki, K., Kozuki, M., Morimoto, N., Ohta, Y., Ikeda, Y., & Abe, K. (2012) · Neurological Research · doi:10.1179/1743132812y.0000000054 · Cited by 49 · see citing works

Alcohol-related neurodegeneration and recovery: mechanisms from animal models.

Crews, F. T. (2008) · Europe PMC (PubMed Central) · Cited by 49 · see citing works

Probiotics-Based Treatment as an Integral Approach for Alcohol Use Disorder in Alcoholic Liver Disease

Fuenzalida, C., Dufeu, M. S., Poníachik, J., Roblero, J. P., Valenzuela-Pérez, L., & Beltrán, C. J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.729950 · Cited by 48 · see citing works

Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression

Nelson, T. E., Hao, C., Manos, J. C., Ransohoff, R. M., & Gruol, D. L. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.02.013 · Cited by 47 · see citing works

Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking

Ezquer, F. E., Morales, P., Quintanilla, M. E., Santapau, D., Lespay‐Rebolledo, C., Ezquer, M., Herrera‐Marschitz, M., & Israel, Y. (2018) · Scientific Reports · doi:10.1038/s41598-018-22750-7 · Cited by 46 · see citing works

Cerebrospinal Fluid Monocyte Chemoattractant Protein‐1 in Alcoholics: Support for a Neuroinflammatory Model of Chronic Alcoholism

Umhau, J. C., Schwandt, M. L., Solomon, M. G., Yuan, P., Nugent, A. C., Zarate, C. A., Drevets, W. C., Hall, S. D., George, D. T., & Heilig, M. A. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12367 · Cited by 45 · see citing works

Nalmefene Prevents Alcohol‐Induced Neuroinflammation and Alcohol Drinking Preference in Adolescent Female Mice: Role of TLR4

Montesinos, J., Gil, A., & Guerri, C. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13416 · Cited by 45 · see citing works

Minocycline blocks traumatic brain injury-induced alcohol consumption and nucleus accumbens inflammation in adolescent male mice

Karelina, K., Nicholson, S., & Weil, Z. M. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.01.012 · Cited by 44 · see citing works

Stress and Withdrawal from Chronic Ethanol Induce Selective Changes in Neuroimmune mRNAs in Differing Brain Sites

Knapp, D. J., Harper, K. M., Whitman, B. A., Zimomra, Z. R., & Breese, G. R. (2016) · Brain Sciences · doi:10.3390/brainsci6030025 · Cited by 43 · see citing works

Bioinformatics Analyses Reveal Age-Specific Neuroimmune Modulation as a Target for Treatment of High Ethanol Drinking

Agrawal, R. G., Owen, J. A., Levin, P. S., Hewetson, A., Berman, A., Franklin, S. R., Hogue, R. J., Chen, Y., Walz, C., Colvard, B. D., et al. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12288 · Cited by 42 · see citing works

Role of astrocytic glutamate transporter in alcohol use disorder

Ayers-Ringler, J. R., Jia, Y., Qiu, Y., & Choi, D. (2016) · World Journal of Psychiatry · doi:10.5498/wjp.v6.i1.31 · Cited by 43 · see citing works

Neuroinflammation as a neurotoxic mechanism in alcoholism: Commentary on “Increased MCP-1 and microglia in various regions of human alcoholic brain”

Sullivan, E. V., & Zahr, N. M. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.05.016 · Cited by 40 · see citing works

Effects of ethanol on immune response in the brain: region-specific changes in aged mice

Kane, C. J. M., Phelan, K. D., Douglas, J. C., Wagoner, G., Johnson, J. W., Xu, J., & Drew, P. D. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-66 · Cited by 39 · see citing works

Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice

Truitt, J., Blednov, Y. A., Benavidez, J. M., Black, M., Ponomareva, O. Y., Law, J., Merriman, M., Horani, S., Jameson, K. G., Lasek, A. W., et al. (2016) · eNeuro · doi:10.1523/eneuro.0256-16.2016 · Cited by 39 · see citing works

Toll-like receptor 3 dynamics in female C57BL/6J mice: Regulation of alcohol intake

Warden, A. S., Azzam, M. M., DaCosta, A., Mason, S., Blednov, Y. A., Messing, R. O., Mayfield, R. D., & Harris, R. A. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.12.006 · Cited by 39 · see citing works

Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data

Blednov, Y. A., Mayfield, R. D., Belknap, J. K., & Harris, R. A. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00780.x · Cited by 38 · see citing works

Prenatal exposure to ethanol stimulates hypothalamic CCR2 chemokine receptor system: Possible relation to increased density of orexigenic peptide neurons and ethanol drinking in adolescent offspring

Chang, G., Karatayev, O., & LEIBOWITZ, S. F. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.020 · Cited by 37 · see citing works

Chronic Intracerebroventricular Infusion of Monocyte Chemoattractant Protein‐1 Leads to a Persistent Increase in Sweetened Ethanol Consumption During Operant Self‐Administration But Does Not Influence Sucrose Consumption in Long‐Evans Rats

Valenta, J. P., & Gonzales, R. A. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12928 · Cited by 36 · see citing works

Atorvastatin and pitavastatin protect cerebellar Purkinje cells in AD model mice and preserve the cytokines MCP-1 and TNF-α

Kozuki, M., Kurata, T., Miyazaki, K., Morimoto, N., Ohta, Y., Ikeda, Y., & Abe, K. (2011) · Brain Research · doi:10.1016/j.brainres.2011.03.024 · Cited by 34 · see citing works

Chemokines, cytokines and substance use disorders

Ahearn, O., Watson, M. N., & Rawls, S. M. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108511 · Cited by 34 · see citing works

Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression

Bray, J. G., Reyes, K. C., Roberts, A. J., Ransohoff, R. M., & Gruol, D. L. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.11.007 · Cited by 34 · see citing works

Glial abnormalities in substance use disorders and depression: Does shared glutamatergic dysfunction contribute to comorbidity?

Niciu, M. J., Henter, I. D., Sanacora, G., & Zarate, C. A. (2013) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2013.829585 · Cited by 34 · see citing works

Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review

Vena, A. A., Zandy, S. L., Cofresí, R. U., & Gonzales, R. A. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107573 · Cited by 32 · see citing works

Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function

Hernandez, R. V., Puro, A., Manos, J. C., Huitrón‐Reséndiz, S., Reyes, K. C., Liu, K., Vo, K., Roberts, A. J., & Gruol, D. L. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.12.015 · Cited by 29 · see citing works

Alcohol vapor exposure differentially impacts mesocorticolimbic cytokine expression in a sex-, region-, and duration-specific manner

Baxter-Potter, L. N., Henricks, A. M., Berger, A. L., Bieniasz, K. V., Lugo, J. M., & McLaughlin, R. J. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.01.015 · Cited by 29 · see citing works

Hypothalamic CCL2/CCR2 Chemokine System: Role in Sexually Dimorphic Effects of Maternal Ethanol Exposure on Melanin-Concentrating Hormone and Behavior in Adolescent Offspring

Chang, G., Karatayev, O., Halkina, V., Edelstien, J., Ramirez, E. B. D., & LEIBOWITZ, S. F. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0637-18.2018 · Cited by 27 · see citing works

Assessment of Extracellular Cytokines in the Hippocampus of the Awake Behaving Rat Using Large‐Molecule Microdialysis Combined with Multiplex Arrays After Acute and Chronic Ethanol Exposure

Gano, A., Vore, A. S., Sammakia, M. N., & Terrence Deak, B. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13963 · Cited by 27 · see citing works

Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice

Lowe, P., Cho, Y., Tornai, D., Çoban, Ş., Catalano, D. E., & Szabó, G. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14272 · Cited by 27 · see citing works

The Neuroimmune Transcriptome and Alcohol Dependence: Potential for Targeted Therapies

Warden, A. S., Erickson, E. K., Robinson, G., Harris, R. A., & Mayfield, R. D. (2016) · Pharmacogenomics · doi:10.2217/pgs-2016-0062 · Cited by 26 · see citing works

Tigecycline Reduces Ethanol Intake in Dependent and Nondependent Male and Female C57 BL /6J Mice

Bergeson, S. E., Nipper, M. A., Jensen, J. P., Helms, M. L., & Finn, D. A. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13251 · Cited by 25 · see citing works

Quantitative Trait Locus Mapping for Acute Functional Tolerance to Ethanol in the L × S Recombinant Inbred Panel

Bennett, B., Downing, C., Carosone‐Link, P., Ponicsan, H., Ruf, C., & Johnson, T. E. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00296.x · Cited by 24 · see citing works

The effects of lipopolysaccharide exposure on social interaction, cytokine expression, and alcohol consumption in male and female mice

Ramirez, E. B. D., Arnold, M. E., McConnell, K. T., Solomon, M. G., Amico, K. N., & Schank, J. R. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114159 · Cited by 23 · see citing works

Effective Reduction in High Ethanol Drinking by Semisynthetic Tetracycline Derivatives

Syapin, P. J., Martinez, J. M., Curtis, D. C., Marquardt, P. C., Allison, C. L., Groot, J. A., Baby, C., Al-Hasan, Y. M., Segura‐Ulate, I., Scheible, M., et al. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13253 · Cited by 23 · see citing works

Identifying Quantitative Trait Loci (QTLs) and Genes (QTGs) for Alcohol-Related Phenotypes in Mice

Milner, L. C., & Buck, K. J. (2010) · International review of neurobiology · doi:10.1016/s0074-7742(10)91006-4 · Cited by 22 · see citing works

Stress- and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders

Smiley, C. E., & Wood, S. K. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108212 · Cited by 23 · see citing works

Conditioned effects of ethanol on the immune system

Gano, A., Pautassi, R. M., Doremus‐Fitzwater, T. L., & Terrence Deak, B. (2017) · Experimental Biology and Medicine · doi:10.1177/1535370217694097 · Cited by 22 · see citing works

TLR4‐MyD88 signalling: a molecular target for alcohol actions

Pandey, S. C. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01695.x · Cited by 22 · see citing works

Ethanol Induction of Innate Immune Signals Across BV2 Microglia and SH-SY5Y Neuroblastoma Involves Induction of IL-4 and IL-13

Lawrimore, C. J., Coleman, L. G., Zou, J., & Crews, F. T. (2019) · Brain Sciences · doi:10.3390/brainsci9090228 · Cited by 21 · see citing works

CCL2/CCR2 Chemokine System in Embryonic Hypothalamus: Involvement in Sexually Dimorphic Stimulatory Effects of Prenatal Ethanol Exposure on Peptide-Expressing Neurons

Chang, G., Karatayev, O., Boorgu, D. S. S. K., & LEIBOWITZ, S. F. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.10.013 · Cited by 20 · see citing works

Neuroimmune Genes and Alcohol Drinking Behavior

Harris, R. A., & Blednov, Y. A. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4729-0_13 · Cited by 20 · see citing works

Vascular Endothelial Growth Factor as a Potential Biomarker of Neuroinflammation and Frontal Cognitive Impairment in Patients with Alcohol Use Disorder

Requena-Ocaña, N., Flores-López, M., Papaseit, E., García‐Marchena, N., Ruiz, J. J., Ortega-Pinazo, J., Serrano, A., Pavón, F. J., Farré, M., Suárez, J., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10050947 · Cited by 18 · see citing works

Gene expression profiling reveals a lingering effect of prenatal alcohol exposure on inflammatory-related genes during adolescence and adulthood

Gano, A., Prestia, L., Middleton, F. A., Youngentob, S. L., Ignacio, C., & Terrence Deak, B. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155126 · Cited by 18 · see citing works

Treatment- and Population-Dependent Activity Patterns of Behavioral and Expression QTLs

Ziebarth, J., Cook, M., Wang, X.-S., Williams, R. W., Lu, L., & Cui, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031805 · Cited by 17 · see citing works

Midkine in the mouse ventral tegmental area limits ethanol intake and Ccl2 gene expression

Chen, H., He, D., & Lasek, A. W. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12384 · Cited by 16 · see citing works

Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRF

Breese, G. R., & Knapp, D. J. (2016) · Alcohol · doi:10.1016/j.alcohol.2016.01.005 · Cited by 15 · see citing works

GPCR and Alcohol-Related Behaviors in Genetically Modified Mice

Neasta, J., Darcq, E., Jeanblanc, J., Carnicella, S., & Hamida, S. B. (2020) · Neurotherapeutics · doi:10.1007/s13311-019-00828-y · Cited by 16 · see citing works

Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation

Niedzwiedz‐Massey, V. M., Douglas, J. C., Rafferty, T. M., Johnson, J. W., Holloway, K. N., Berquist, M. D., Kane, C. J. M., & Drew, P. D. (2022) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2022.2128361 · Cited by 17 · see citing works

Phenotyping CCL2 Containing Central Amygdala Neurons Controlling Alcohol Withdrawal-Induced Anxiety

Harper, K. M., Knapp, D. J., Todd, C. A., Balan, I. S., Aurelian, L., Criswell, H. E., & Breese, G. R. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.580583 · Cited by 15 · see citing works

Adolescent neuroimmune function and its interaction with alcohol

Doremus‐Fitzwater, T. L., & Deak, T. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2021.08.006 · Cited by 15 · see citing works

Transgenic mice with increased astrocyte expression of CCL2 show altered behavioral effects of alcohol

Bray, J. G., Roberts, A. J., & Gruol, D. L. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.04.009 · Cited by 15 · see citing works

Cyanidin prevents MDPV withdrawal-induced anxiety-like effects and dysregulation of cytokine systems in rats

Inan, S., Meissler, J. J., Shekarabi, A., Foss, J., Wiah, S., Eisenstein, T. K., & Rawls, S. M. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148310 · Cited by 14 · see citing works

Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset

Holloway, K. N., Douglas, J. C., Rafferty, T. M., Majewska, A. K., Kane, C. J. M., & Drew, P. D. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1154637 · Cited by 12 · see citing works

Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies

Blednov, Y. A., Ponomarev, I., Geil, C., Bergeson, S., Koob, G. F., & Harris, R. A. (2012) · Addiction Biology · doi:10.1111/j.1369-1600.2010.00284.x · Cited by 251 · see citing works

Altered behavioural effects of ethanol in mice lacking CCK-2 receptors

Abramov, U., Kõks, S., & Vasar, E. (2006) · Murdoch University Research Portal

Mice Deficient in Corticotropin-Releasing Factor Receptor Type 2 Exhibit Normal Ethanol-Associated Behaviors

Sharpe, A. L., Coste, S. C., Burkhart‐Kasch, S., Li, N., Stenzel‐Poore, M. P., & Phillips, T. J. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000179371.46716.5e · Cited by 27 · see citing works

Chloride intracellular channels modulate acute ethanol behaviors inDrosophila, Caenorhabditis elegansand mice

Bhandari, P., Hill, J. S., Farris, S. P., Costin, B. N., Martin, I., Chan, C. ‐., Alaimo, J. T., Bettinger, J. C., Davies, A. G., Miles, M. F., et al. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00765.x · Cited by 51 · see citing works

Altered behavioural effects of ethanol and increased voluntary ethanol comsumption in mice lacking CCK2 receptors

Abramov, U., Vasar, E., & Kõks, S. (2005) · Murdoch University Research Portal