Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

D'AMOUR, F. E., & Smith, D. L. (1941) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)03823-6 · Cited by 3,238 · see citing works

Interleukin-1 and interleukin-1 antagonism

Dinarello, C. A. (1991) · Blood · doi:10.1182/blood.v77.8.1627.1627 · Cited by 2,303 · see citing works

Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

Coderre, T. J., Katz, J., Vaccarino, A. L., & Melzack, R. (1993) · Pain · doi:10.1016/0304-3959(93)90161-h · Cited by 1,966 · see citing works

Biology of interleukin 1

Dinarello, C. A. (1988) · The FASEB Journal · doi:10.1096/fasebj.2.2.3277884 · Cited by 1,532 · see citing works

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

Eisenberg, S. P., Evans, R. J., Arend, W. P., Verderber, E. L., Brewer, M. T., Hannum, C. H., & Thompson, R. C. (1990) · Nature · doi:10.1038/343341a0 · Cited by 1,088 · see citing works

Sickness behavior as a new target for drug development

Kent, S., Bluthé, R.-M., Kelley, K. W., & Dantzer, R. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90012-u · Cited by 863 · see citing works

Brainstem Control of Spinal Pain-Transmission Neurons

Fields, H. L., & Basbaum, A. I. (1978) · Annual Review of Physiology · doi:10.1146/annurev.ph.40.030178.001245 · Cited by 834 · see citing works

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

Dinarello, C. A., & Thompson, R. C. (1991) · Immunology Today · doi:10.1016/0167-5699(91)90142-g · Cited by 729 · see citing works

Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue

Ferreira, S. H., Lorenzetti, B. B., Bristow, A. F., & Poole, S. (1988) · Nature · doi:10.1038/334698a0 · Cited by 624 · see citing works

Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.

Beasley, D., Schwartz, J. H., & Brenner, B. M. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115036 · Cited by 398 · see citing works

Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: a pathway for the induction of non-specific symptoms of sickness?

van Dam, A.-M., Brouns, M., Louisse, S., & Berkenbosch, F. (1992) · Brain Research · doi:10.1016/0006-8993(92)91588-6 · Cited by 333 · see citing works

Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1.

Kent, S., Bluthé, R.-M., Dantzer, R., Hardwick, A. J., KELLEY, K. W., Rothwell, N. J., & Vannice, J. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.19.9117 · Cited by 322 · see citing works

Functions and mechanisms of interleukin 1 in the brain

Rothwell, N. J. (1991) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(91)90623-z · Cited by 321 · see citing works

Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1.

Dunn, A. J. (1992) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)11171-3 · Cited by 302 · see citing works

Brain macrophages synthesize interleukin‐1 and interleukin‐1 mRNAs in vitro

Hetier, E., Ayala‐Sanmartín, J., Denèfle, P., Bousseau, A., Rouget, P., Mallat, M., & Prochiantz, A. (1988) · Journal of Neuroscience Research · doi:10.1002/jnr.490210230 · Cited by 287 · see citing works

The interleukins 1

Mizel, S. B. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.12.2676681 · Cited by 286 · see citing works

The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats

Ren, K., Williams, G. M., Hylden, J. L. K., Ruda, M. A., & Dubner, R. A. (1992) · European Journal of Pharmacology · doi:10.1016/0014-2999(92)90301-j · Cited by 238 · see citing works

An IL-1 inhibitor from human monocytes. Production and characterization of biologic properties.

Arend, W. P., Joslin, F. G., Thompson, R. C., & Hannum, C. H. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.143.6.1851 · Cited by 206 · see citing works

Contribution of protein kinase C to central sensitization and persistent pain following tissue injury

Coderre, T. J. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90097-q · Cited by 176 · see citing works

Convulsants induce interleukin-1β messenger RNA in rat brain

Minami, M., Kuraishi, Y., Yamaguchi, T., Nakai, S., Hirai, Y., & Satoh, M. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91221-d · Cited by 158 · see citing works

Arachidonic Acid Increases Inositol Phospholipid Metabolism and Glutamate Release in Synaptosomes Prepared from Hippocampal Tissue

Lynch, M. A., & Voss, K. L. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb08841.x · Cited by 133 · see citing works

Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat

Dickenson, A. H., & Aydar, E. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90700-4 · Cited by 124 · see citing works

Is there a facilitating component to central pain modulation?

Fields, H. L. (1992) · APS Journal · doi:10.1016/1058-9139(92)90030-g · Cited by 100 · see citing works

Interleukin-1 induces analgesia in mice by a central action

Nakamura, H., Nakanishi, K., Kita, A., & Kadokawa, T. (1988) · European Journal of Pharmacology · doi:10.1016/0014-2999(88)90040-4 · Cited by 96 · see citing works

Involvement of spinal opioid systems in footshock-induced analgesia: Antagonism by naloxone is possible only before induction of analgesia

Watkins, L. R., & Mayer, D. J. (1982) · Brain Research · doi:10.1016/0006-8993(82)90314-6 · Cited by 61 · see citing works

Parallel activation of multiple spinal opiate systems appears to mediate ‘non-opiate’ stress-induced analgesias

Watkins, L. R., Wiertelak, E. P., Grisel, J. E., Silbert, L. H., & Maier, S. F. (1992) · Brain Research · doi:10.1016/0006-8993(92)91033-b · Cited by 58 · see citing works

Autoradiographic analysis of 125I-substance P binding in rat spinal cord following chronic constriction injury of the sciatic nerve

Aanonsen, L. M., Kajander, K. C., Bennett, G. J., et al. (1992) · Brain Research · doi:10.1016/0006-8993(92)91556-t · Cited by 52 · see citing works

Role of Symbol and opiate receptors in nociception during and after ischaemia in rats

Sher, G. D., Cartmell, S. M., Gelgor, L., et al. (1992) · Pain · doi:10.1016/0304-3959(92)90148-5 · Cited by 49 · see citing works

Vagal modulation of nociception

Gebhart, G. F., & Randich, A. (1992) · APS Journal · doi:10.1016/s1058-9139(06)80007-0 · Cited by 47 · see citing works

Interleukin-1 potentiates bradykinin- and TNFα-induced PGE2 release

O'Neill, L. A. J., & Lewis, G. P. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90052-6 · Cited by 36 · see citing works

Endogenous pain facilitory systems Antianalgesia and hyperalgesia

Maier, S. F., Wiertelak, E. P., & Watkins, L. R. (1992) · APS Journal · doi:10.1016/1058-9139(92)90009-2 · Cited by 28 · see citing works

The induction of pain: an integrative review

Millan, M. J. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00048-3 · Cited by 1,774 · see citing works

Twenty years of research on cytokine-induced sickness behavior

Dantzer, R., & Kelley, K. W. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.09.006 · Cited by 1,420 · see citing works

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

Leonard, B., & Maes, M. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.005 · Cited by 805 · see citing works

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

Maes, M., Berk, M., Goehler, L., Song, C., Anderson, G., Gałecki, P., & Leonard, B. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-66 · Cited by 629 · see citing works

Vagal immune-to-brain communication: a visceral chemosensory pathway

Goehler, L. E., Gaykema, R. P. A., Hansen, M. K., Anderson, K., Maier, S. F., & Watkins, L. R. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00219-8 · Cited by 525 · see citing works

Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication

Watkins, L. R., Goehler, L. E., Relton, J. K., Tartaglia, N., Silbert, L., Martin, D., & Maier, S. F. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(94)11105-r · Cited by 516 · see citing works

Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications

Stratton, P., & Berkley, K. J. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq050 · Cited by 442 · see citing works

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.08.026 · Cited by 443 · see citing works

The Pain of Being Sick: Implications of Immune-to-Brain Communication for Understanding Pain

Watkins, L. R., & Maier, S. F. (2000) · Annual Review of Psychology · doi:10.1146/annurev.psych.51.1.29 · Cited by 388 · see citing works

Bi-directional immune–brain communication: implications for understanding stress, pain, and cognition

Maier, S. F. (2003) · Brain Behavior and Immunity · doi:10.1016/s0889-1591(03)00032-1 · Cited by 300 · see citing works

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress**This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder.

Deak, T., Nguyen, K. T., Ehrlich, A. L., Watkins, L. R., Spencer, R. L., Maier, S. F., Licinio, J., Wong, M.-L., Chrousos, G. P., Webster, E., et al. (1999) · Endocrinology · doi:10.1210/endo.140.1.6415 · Cited by 242 · see citing works

Central Proinflammatory Cytokines and Pain Enhancement

Wieseler-Frank, J., Maier, S. F., & Watkins, L. R. (2005) · Neurosignals · doi:10.1159/000087655 · Cited by 198 · see citing works

Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol

BLEDNOV, Y., BERGESON, S., WALKER, D., FERREIRA, V, KUZIEL, W., & HARRIS, R. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.06.026 · Cited by 149 · see citing works

Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats

Wang, X. (2002) · World Journal of Gastroenterology · doi:10.3748/wjg.v8.i3.540 · Cited by 143 · see citing works

A Functional riboSNitch in the 3′ Untranslated Region of<i>FKBP5</i>Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain

Linnstaedt, S. D., Riker, K. D., Rueckeis, C. A., Kutchko, K. M., Lackey, L., McCarthy, K. R., Tsai, Y.-H., Parker, J. S., Kurz, M. C., Hendry, P. L., et al. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.3458-17.2018 · Cited by 66 · see citing works

Systemic lipopolysaccharide influences rectal sensitivity in rats: role of mast cells, cytokines, and vagus nerve

Coelho, A.-M., Fioramonti, J., & Buéno, L. (2000) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2000.279.4.g781 · Cited by 63 · see citing works

Chronic fatigue syndrome from vagus nerve infection: a psychoneuroimmunological hypothesis

VanElzakker, M. B. (2013) · Medical Hypotheses · doi:10.1016/j.mehy.2013.05.034 · Cited by 58 · see citing works

Lifetime modulation of the pain system via neuroimmune and neuroendocrine interactions

Zouikr, I., & Karshikoff, B. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00276 · Cited by 45 · see citing works

The dose‐related effects of paracetamol on hyperalgesia and nociception in the rat

Bianchi, M., & Panerai, A. E. (1996) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1996.tb15164.x · Cited by 41 · see citing works

Environmentally induced antinociception and hyperalgesia in rats and mice

Cornélio, A. M., Mendes-Gomes, J., Fugimoto, J. S., Morgan, M. M., & Nunes‐de‐Souza, R. L. (2011) · Brain Research · doi:10.1016/j.brainres.2011.07.058 · Cited by 15 · see citing works

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Hargreaves, K., Dubner, R. A., Brown, F. J., Flores, C., & Joris, J. L. (1988) · Pain · doi:10.1016/0304-3959(88)90026-7 · Cited by 5,155 · see citing works

Neural Mechanisms of Cutaneous Nociceptive Pain

Koltzenburg, M. (2000) · Clinical Journal of Pain · doi:10.1097/00002508-200009001-00004 · Cited by 82 · see citing works

Neonatal capsaicin attenuates mechanical nociception in the rat

Khasar, S. G., & Levine, J. D. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12394-6 · Cited by 12 · see citing works