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Social deficits, stereotypy and early emergence of repetitive behavior in the C58/J inbred mouse strain
Open accessAbstract
Mouse lines with behavioral phenotypes relevant to symptoms in neurodevelopmental disorders may provide models to test hypotheses about disease etiology and to evaluate potential treatments. The present studies were designed to confirm and expand earlier work on the intriguing behavioral profile of the C58/J inbred strain, including low social approach and aberrant repetitive movements. Additional tests were selected to reflect aspects of autism, a severe neurodevelopmental disorder characterized by emergence of symptoms early in life, higher prevalence in males, social deficits and abnormal repetitive behavior. Mice from the C57BL/6J inbred strain, which has a similar genetic lineage and physical appearance to C58/J, served as a comparison group. Our results revealed that C58/J mice display elevated activity levels by postnatal day 6, which persist into adulthood. Despite normal olfactory ability, young adult male C58/J mice showed deficits in social approach in the three-chambered choice assay and failed to demonstrate social transmission of food preference. In contrast, female C58/J mice performed similarly to female C57BL/6J mice in both social tests. C58/J mice of both sexes demonstrated abnormal repetitive behaviors, displaying excessive jumping and back flipping in both social and non-social situations. These stereotypies were clearly evident in C58/J pups by postnatal days 20-21, and were also observed in C58/J dams during a test for maternal behavior. Overall, the strain profile for C58/J, including spontaneously developing motor stereotypies emerging early in the developmental trajectory, and social deficits primarily in males, models multiple components of the autism phenotype.
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“Several naturally occurring inbred strains of mice display behavioral features that recapitulate diagnostic symptoms of neurodevelopmental disorders (59–70).”
From Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism (2012) · cites this paper as [67]
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“C58/J (C58) is another commercially available inbred strain of mouse that displays high levels of stereotyped vertical jumping behaviors, relevant to the motor stereotypies of the third diagnostic symptom category of autism (65, 67).”
From Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism (2012) · cites this paper as [67]
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Cites
Castelli, F. (2002) · Brain · doi:10.1093/brain/awf189 · Cited by 1,377
The Epidemiology of Autism Spectrum Disorders
Newschaffer, C. J., Croen, L. A., Daniels, J., Giarelli, E., Grether, J. K., Levy, S. E., Mandell, D. S., Miller, L. A., Pinto-Martin, J., Reaven, J., et al. (2007) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.28.021406.144007 · Cited by 1,228
Autism‐like behavioral phenotypes in BTBR T+tf/J mice
McFarlane, H. G., Kusek, G. K., Yang, M., Phoenix, J. L., Bolivar, V. J., & Crawley, J. N. (2008) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2007.00330.x · Cited by 812
Self-citationMouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
MOY, S., NADLER, J., YOUNG, N., PEREZ, A., HOLLOWAY, L., BARBARO, R., BARBARO, J., WILSON, L., THREADGILL, D., & LAUDER, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.07.030 · Cited by 776
Self-citationAutomated apparatus for quantitation of social approach behaviors in mice
Nadler, J. J., Moy, S. S., Dold, G., Trang, D., Simmons, N., Perez, A., Young, N. B., Barbaro, R. P., Piven, J., Magnuson, T. R., et al. (2004) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2004.00071.x · Cited by 775
Self-citationExploratory behavior models of anxiety in mice
Crawley, J. N. (1985) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(85)90030-2 · Cited by 756
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Leypold, B. G., Yu, C., Leinders‐Zufall, T., Kim, M. M., Zufall, F., & Axel, R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082127599 · Cited by 572
Lord, C., Cook, E. H., Leventhal, B. L., & Amaral, D. G. (2000) · Neuron · doi:10.1016/s0896-6273(00)00115-x · Cited by 555
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Kennedy, D. P., & Courchesne, E. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.10.052 · Cited by 515
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Silverman, J. L., Pride, M. C., Hayes, J. E., Puhger, K. R., Butler-Struben, H. M., Baker, S., & Crawley, J. N. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.66 · Cited by 215
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Molenhuis, R. T., de Visser, L., Bruining, H., & Kas, M. J. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.01.013 · Cited by 71
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Canal, C. E., Felsing, D. E., Liu, Y., Zhu, W., Wood, J. T., Perry, C. K., Vemula, R., & Booth, R. G. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00099 · Cited by 43
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Self-citationChen, Y., Liu, S., Xu, H., Zheng, H., Bai, C., Pan, W., Zhou, H., Liao, M., Huang, C., & Dong, Q. (2019) · Toxicology · doi:10.1016/j.tox.2019.02.016 · Cited by 41
Pobbe, R. L. H., Pearson, B. L., Blanchard, D. C., & Blanchard, R. J. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.02.024 · Cited by 40
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Self-citationLim, C., Kim, M. J., Choi, J. E., Islam, M. A., Lee, Y.-K., Xiong, Y., Shim, K.-W., Yang, J.-E., Lee, R. U., Lee, J., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01216-9 · Cited by 34
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Yang, L., Faraone, S. V., & Zhang‐James, Y. (2016) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32415 · Cited by 25
Shorter, K. R., Owen, A., Anderson, V., Hall-South, A. C., Hayford, S., Cakora, P., Crossland, J. P., Georgi, V. R. M., Perkins, A. E., Kelly, S. J., et al. (2014) · Behavior Genetics · doi:10.1007/s10519-013-9640-8 · Cited by 22
Rigby, M. J., Orefice, N. S., Lawton, A. J., Ma, M., Shapiro, S. L., Yi, S. Y., Dieterich, I. A., Frelka, A., Miles, H. N., Pearce, R. A., et al. (2022) · Brain Communications · doi:10.1093/braincomms/fcac002 · Cited by 21
Wilkes, B. J., Bass, C., Korah, H. E., Febo, M., & Lewis, M. H. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00158-9 · Cited by 24
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Self-citationOlexová, L., Talarovičová, A., Lewis-Evans, B., Borbélyová, V., & Kršková, L. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.10.004 · Cited by 13
Muehlmann, A. M., Bliznyuk, N., Duerr, I., Yang, T. P., & Lewis, M. H. (2019) · Developmental Psychobiology · doi:10.1002/dev.21914 · Cited by 15
Murta, V., Seiffe, A., & Depino, A. M. (2023) · Sexes · doi:10.3390/sexes4030024 · Cited by 13
Dudas, A., Nakahara, T. S., Pellissier, L. P., & Chamero, P. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105686 · Cited by 11
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Rizzo, S. J. S. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3661-8_17 · Cited by 7
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Bauman, M. D., Crawley, J. N., & Berman, R. F. (2010) · Wiley eBooks · doi:10.1002/9780470015902.a0022368 · Cited by 5
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Berg, E. L., & Silverman, J. L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-816393-1.00010-5 · Cited by 4
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Choudhary, A., Geuther, B. Q., Sproule, T. J., Beane, G., Kohar, V., Trapszo, J., & Kumar, V. (2025) · eLife · doi:10.7554/elife.107259 · Cited by 5
Balagangadharan, K., Lu, H., Steenhagen, A., Dong, Q., Gray, M., Rigby, M. J., Endresen, A., Chang, Q., Li, L., & Puglielli, L. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03228-1 · Cited by 2
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Metadata
- Authors
- Ryan, B. C., Young, N. B., Crawley, J. N., Bodfish, J. W., & Moy, S. S.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Ryan, Bryce C.
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 208
- Issue
- 1
- Pages
- 178-188
- ISSN
- 0166-4328 (ISSN-L)
- PMC
- PMC2822076
- OpenAlex
- W1998109533
- Cited by
- 135
- References
- 63
- Citations by year
- 2026: 8 · 2025: 9 · 2024: 6 · 2023: 7 · 2022: 8 · 2021: 10 · 2020: 4 · 2019: 9 · 2018: 5 · 2017: 3 · 2016: 12 · 2015: 9 · 2014: 10 · 2013: 8 · 2012: 16
- FWCI
- 4.36
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- InSPIRe@Redlands (University of Redlands) (submittedVersion)
- UNC Libraries
- Funders
- National Institutes of Health
- National Institute of Mental Health (HD40127, R21MH084132, R01 MH73402, MH73402, R21MH085254, R01MH073402, MH084132)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (T32-HD-40127, P30-HD03110, P30HD003110, T32HD040127)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- autism model, social dysfunction, social approach, repetitive behavior, motor stereotypies, social transmission of food preference, sex differences, maternal behavior, neurodevelopmental disorders, behavioral phenotypes
- MeSH terms
- Age Factors, Analysis of Variance, Animals, Animals, Newborn, Behavior, Animal, Body Weight, Choice Behavior, Female, Habituation, Psychophysiologic, Interpersonal Relations, Locomotion, Male, Maternal Behavior, Mice, Inbred Strains, Olfactory Pathways, Social Behavior Disorders, Stereotyped Behavior, Statistics, Nonparametric, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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