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A critical evaluation of neuroprotective and neurodegenerative MicroRNAs in Alzheimer's disease

Reddy, P. Hemachandra, Tonk, Sahil, Kumar, Subodh, Vijayan, Murali, Kandimalla, Ramesh, Kuruva, Chandra Sekhar, Reddy, Arubala P.·2017·Biochemical and Biophysical Research Communications
DOI 10.1016/j.bbrc.2016.08.067PMC PMC5343756
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  1. [1]Selkoe DJ Alzheimer’s Disease: Genes, Proteins, and Therapy Physiol Rev 81 2001 741 766 11274343
  2. [2]Mattson MP Pathways towards and away from Alzheimer’s disease Nature 5 2004 631 639 PMC3091392 15295589
  3. [4]Reddy PH Manczaka M Maoa P Calkinsa MJ Reddy AP Shirendeba U Amyloid-β and mitochondria in aging and Alzheimer’s disease: Implications for synaptic damage and cognitive decline J Alz Dis 20 2010 S499 S512 PMC3059092 20413847
  4. [6]Reddy PH Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer’s disease Brain Res 1415 2011 136 148 21872849 PMC3176990
  5. [7]Reddy PH McWeeney S Mapping cellular transcriptosomes in autopsied Alzheimer’s disease subjects and relevant animal models Neurobiol Aging 27 2006 1060 1077 16157420
  6. [8]Mao P Reddy PH Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer’s disease: implications for early intervention and therapeutics Biochim Biophys Acta 1812 2011 1359 1370 21871956 PMC3185172
  7. [9]Nicolas FE Lopez-Martinez AF MicroRNAs in human diseases Recent Pat DNA Gene Seq 4 2010 142 154 21288192
  8. [10]Bao B Ali S Kong D Sarkar SH Wang Z Banerjee S Aboukameel A Padhye S Philip PA Sarkar FH Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer PLoS One 6 2011 e17850 21408027 PMC3052388
  9. [11]Quiat D Olson EN MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment J Clin Invest 123 2013 11 18 23281405 PMC3533276
  10. [12]Wei C Henderson H Spradley C Li L Kim IK Kumar S Hong N Arroliga AC Gupta S Circulating miRNAs as potential marker for pulmonary hypertension PLoS One 8 2013 e64396 23717609 PMC3662705
  11. [13]Papagregoriou G Erguler K Dweep H Voskarides K Koupepidou P Athanasiou Y Pierides A Gretz N Felekkis KN Deltas C A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy PLoS One 7 2012 e31021 22319602 PMC3271095
  12. [14]Koutsis G Siasos G Spengos K The emerging role of microRNA in stroke Curr Top Med Chem 13 2013 1573 1588 23745809
  13. [15]Beveridgea NJ Cairnsa MJ MicroRNA dysregulation in schizophrenia Neurobiology of Disease 46 2012 263 271 22207190
  14. [16]Kocerha J Liu Y Willoughby D Chidamparam K Benito J Nelson K Xu Y Chi T Engelhardt H Moran S Yang SH Li SH Li XJ Larkin K Neumann A Banta H Yang JJ Chan AW Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys BMC Neurosci 14 2013 88 23957861 PMC3751855
  15. [17]Mouradian MM MicroRNAs in Parkinson’s disease Neurobiol Dis 46 2012 279 284 22245218
  16. [18]Delay C Hebert SS MicroRNAs and Alzheimer’s disease mouse models: Current Insights and Future Research Avenues Int J Alz Dis 2011 2011 894938 PMC3150778 21826259
  17. [19]Nicolas G Wallon D Goupil C Richard AC Pottier C Dorval V Sarov-Rivière M Riant F Hervé D Amouyel P Guerchet M Ndamba-Bandzouzi B Mbelesso P Dartigues JF Lambert JC Preux PM Frebourg T Campion D Hannequin D Tournier-Lasserve E Hébert SS Rovelet-Lecrux A Mutation in the 3′untranslated region of APP as a genetic determinant of cerebral amyloid angiopathy Eur J Hum Genet 24 2016 92 98 25828868 PMC4795229
  18. [20]Kumar S Reddy PH Are circulating microRNAs peripheral biomarkers for Alzheimer’s disease? Biochim Biophys Acta 1862 2016 1617 1627 27264337 PMC5343750
  19. [21]Karch CM Goate AM Alzheimer’s disease risk genes and mechanisms of disease pathogenesis Biol Psychiatry 77 2015 43 51 24951455 PMC4234692
  20. [22]Long JM Lahiri DK Current drug targets for modulating Alzheimer’s amyloid precursor protein: role of specific micro-RNA species Curr Med Chem 18 2011 3314 3321 21728971
  21. [23]Maffioletti E Tardito D Gennarelli M Bocchio-Chiavetto L Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders Front Cell Neurosci 8 2014 75 24653674 PMC3949217
  22. [24]Peters L Meister G Argonaute proteins: mediators of RNA silencing Mol Cell 26 2007 611 623 17560368
  23. [25]Eulalio A Huntzinger E Nishihara T Rehwinkel J Fauser M Izaurralde E Deadenylation is a widespread effect of miRNA regulation RNA 15 2009 21 32 19029310 PMC2612776
  24. [27]Bartel DP MicroRNAs: Genomics, Biogenesis, Mechanism and Function Cell 116 2004 281 297 14744438
  25. [28]Hooten NN Fitzpatrick M Wood WH De S Ejiogu N Zhang Y Mattison JA Becker KG Zonderman AB Evans MK Age-related changes in microRNA levels in serum Aging 5 2013 725 740 24088671 PMC3838776
  26. [30]Shao NY Hu HY Yan Z Xu Y Hu H Menzel C Li N Chen W Khaitovich P Comprehensive survey of human brain microRNA by deep sequencing BMC Genomics 11 2010 4 20591156 PMC2996937
  27. [32]Davis TH Cuellar TL Koch SM Barker AJ Harfe BD McManus MT Ullian EM Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus J Neurosci 28 2008 4322 4330 18434510 PMC3844796
  28. [33]Kawase-Koga Y Low R Otaegi G Pollock A Deng H Eisenhaber F Maurer-Stroh S Sun T RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells J Cell Sci 123 2010 586 594 20103535 PMC2818196
  29. [34]Junn E Mouradian MM MicroRNAs in neurodegenerative diseases and their therapeutic potential Pharmacol Ther 133 2012 142 150 22008259 PMC3268953
  30. [35]Nunez-Iglesias J Liu CC Morgan TE Finch CE Zhou XJ Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer’s disease cortex reveals altered miRNA regulation PLoS One 5 2010 e8898 20126538 PMC2813862
  31. [36]Schonrock N Gotz J Decoding the non-coding RNAs in Alzheimer’s disease Cell Mol Life Sci 69 2012 3543 3559 22955374 PMC11114718
  32. [37]Wang WX Huang Q Hu Y Stromberg AJ Nelson PT Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter Acta Neuropathol 121 2011 193 205 20936480 PMC3073518
  33. [39]Patel N Hoang D Miller N Ansaloni S Huang Q Rogers JT Lee JC Saunders AJ MicroRNAs can regulate human APP levels Mol Neurodegener 3 2008 10 18684319 PMC2529281
  34. [40]Delay C Calon F Mathews P Hébert SS Alzheimer-specific variants in the 3′UTR of Amyloid precursor protein affect microRNA function Mol Neurodegener 6 2011 70 21982160 PMC3195754
  35. [41]Smith P Hashimi AA Girard J Delay C Hébert SS In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs J Neurochem 116 2011 240 247 21062284
  36. [42]Fang M Wang J Zhang X Geng Y Hu Z Rudd JA Ling S Chen W Han S The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer’s disease Toxicology Letters 209 2012 94 105 22178568
  37. [43]Schonrock N Humphreys DT Preiss T Götz J Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β J Mol Neurosci 46 2012 324 335 21720722
  38. [44]Boissonneault V Plante I Rivest S Provost P MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1 J Biol Chem 284 2009 1971 1981 18986979 PMC2908704
  39. [45]Wang H Liu J Zong Y Xu Y Deng W Zhu H Liu Y Ma C Huang L Zhang L Qin C miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer’s disease targets TGF-β type II receptor Brain Res 1357 2010 166 1674 20709030
  40. [46]Schonrock N Ke YD Humphreys D Staufenbiel M Ittner LM Preiss T Götz J Neuronal microRNA deregulation in response to Alzheimer’s disease amyloid-beta PLoS One 5 2010 e11070 20552018 PMC2884018
  41. [47]Kim W Lee Y McKenna ND Yi M Simunovic F Wang Y Kong B Rooney RJ Seo H Stephens RM Sonntag KC miR-126 contributes to Parkinson’s disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling Neurobiol Aging 35 2014 1712 1721 24559646 PMC3991567
  42. [48]Yang G Song Y Zhou X Deng Y Liu T Weng G Yu D Pan S MicroRNA-29c targets βsite amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo Mol Med Rep 12 2015 3081 3088 25955795
  43. [49]Zhang J Hu M Teng Z Tang YP Chen C Synaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer’s disease J Neurosci 34 2014 14919 14933 25378159 PMC4220026
  44. [50]Long JM Ray B Lahiri DK MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects J Biol Chem 289 2014 5184 5198 24352696 PMC3931075
  45. [52]Alexandrov PN Zhao Y Jones BM Bhattacharjee S Lukiw WJ Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line J Inorg Biochem 128 2013 267 269 23778113 PMC3797872
  46. [53]Alexandrov PN Dua P Hill JM Bhattacharjee S Zhao Y Lukiw WJ microRNA (miRNA) speciation in Alzheimer’s disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF) Int J Biochem Mol Biol 3 2012 365 373 23301201 PMC3533883
  47. [54]Liu W Liu C Zhu J Shu P Yin B Gong Y Qiang B Yuan J Peng X MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer’s-associated pathogenesis in SAMP8 mice Neurobiol Aging 33 2012 522 534 20619502
  48. [55]Pogue AI Li YY Cui JG Zhao Y Kruck TP Percy ME Tarr MA Lukiw WJ Characterization of an NF-kappaB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells J Inorg Biochem 103 2009 1591 1595 19540598
  49. [56]Augustin R Endres K Reinhardt S Kuhn PH Lichtenthaler SF Hansen J Wurst W Trümbach D Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10 BMC Med Genet 17 2012 13 35 PMC3459808 22594617
  50. [60]Jing L Jya Y Lu J Han R Li J Wang S Peng T Jia Y MicroRNA-9 promotes differentiation of mouse bone mesenchymal stem cells into neurons by Notch signaling Neuro Report 22 2011 206 211 21346646
  51. [61]Bonev B Pisco A Papalopulu N MicroRNA-9 reveals regional diversity of neural progenitors along the anteriorposterior axis Developmental Cell 20 2011 19 32 21238922 PMC3361082
  52. [62]Hébert SS Papadopoulou AS Smith P Galas MC Planel E Silahtaroglu AN Sergeant N Buée L Strooper BD Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration Hum Mol Genet 19 2010 3959 3969 20660113
  53. [63]Carrettiero DC Hernandez I Neveu P Papagiannakopoulos T Kosik KS The cochaperone BAG2 sweeps paired helical filament-insoluble tau from the microtubule J Neurosci 29 2009 2151 2161 19228967 PMC2768429
  54. [65]Lee ST Chu K Jung KH Kim JH Huh JY Yoon H Park DK Lim JY Kim JM Jeon D Ryu H Lee SK Kim M Roh JK miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model Ann Neurol 72 2012 269 277 22926857
  55. [66]Li YY Cui JG Hill JM Bhattacharjee S Zhao Y Lukiw WJ Increased expression of miRNA-146a in Alzheimer’s disease transgenic mouse models Neurosci Lett 487 2011 94 98 20934487 PMC5382794
  56. [68]Song J Lee JE miR-155 is involved in Alzheimer’s disease by regulating T lymphocyte function Front Aging Neurosci 7 2015 61 25983691 PMC4415416
  57. [69]Li Z Gu X Fang Y Xiang J Chen Z microRNA expression profiles in human colorectal cancers with brain metastases Oncol Lett 2 2012 346 350 PMC3464086 22740910
  58. [70]Lukiw WJ Alexandrov PN Regulation of complement factor H (CFH) by multiple miRNAs in Alzheimer’s disease (AD) brain Mol Neurobiol 46 2012 11 19 22302353 PMC3703615
  59. [71]Redis RS Calin S Yang Y You MJ Calin GA Cell-to-cell miRNA transfer: from body homeostasis to therapy Pharmacol Ther 136 2012 169 174 22903157 PMC3855335
  60. [72]Lehmann SM Krüger C Park B Derkow K Rosenberger K Baumgart J Trimbuch T Eom G Hinz M Kaul D Habbel P Kälin R Franzoni E Rybak A Nguyen D Veh R Ninnemann O Peters O Nitsch R Heppner FL Golenbock D Schott E Ploegh HL Wulczyn FG Lehnardt S An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration Nat Neurosci 15 2012 827 835 22610069
  61. [73]Shioya M Obayashi S Tabunoki H Arima K Saito Y Ishida T Satoh J Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3 Neuropathol Appl Neurobiol 36 2010 320 330 20202123
  62. [75]Bian Z Li L-M Tang R Hou DX Chen X Zhang CY Zen K Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions Cell Research 20 2010 1076 1078 20733615
  63. [76]Huang L Mollet S Souquere S Roy FL Ernoult-Lange M Pierron G Dautry F Weil D Mitochondria associate with P-bodies and modulate microRNA-mediated RNA interference J Bio Chem 286 2011 24219 24230 21576251 PMC3129203
  64. [78]Kren BT Wong PY Sarver A Zhang X Zeng Y Steer CJ MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis RNA Bio 6 2009 65 72 19106625 PMC3972804
  65. [79]Chen Z Li Y Zhang H Huang P Luthra R Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression Oncogene 29 2010 4362 4368 20498629
  66. [80]Lung B Zemann A Madej MJ Schuelke M Techritz S Ruf S Bock R Hüttenhofer A Identification of small non-coding RNAs from mitochondria and chloroplasts Nucleic Acids Research 34 2006 3842 3852 16899451 PMC1557801
  67. [81]Barrey E Saint-Auret G Bonnamy B Damas D Boyer O Gidrol X Pre-microRNA and mature microRNA in human mitochondria PLoS One 6 2011 e20220 21637849 PMC3102686
  68. [82]Shinde S Bhadra U A Complex Genome-MicroRNA Interplay in Human Mitochondria BioMed Research International 2015 2015 206382 25695052 PMC4324738
  69. [83]Long B Wang K Li N Murtaza I Xiao J-Y Fan Y-Y Liu C-Y Li W-H Cheng Z Li P miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor Free Radic Biol Med 65 2013 371 379 23867156 PMC4397917
  70. [85]Li J Donath S Li Y Qin D Prabhakar BS Li P miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway PLoS Genet 6 2010 e1000795 20062521 PMC2793031
  71. [86]Wang JX Jiao JQ Li Q Long B Wang K Liu JP Li YR Li PF miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1 Nat Med 17 2011 71 78 21186368
  72. [87]Kandimalla R Reddy PH Multiple faces of dynamin-related protein 1 and its role in Alzheimer’s disease pathogenesis Biochim Biophy Acta 1862 2016 814 828 PMC5343673 26708942
  73. [88]Harries LW MicroRNAs as Mediators of the Ageing Process Genes 5 2014 656 670 25140888 PMC4198923
  74. [89]Hebert SS Horre K Nicolaï L Papadopoulou AS Mandemakers W Silahtaroglu AN Kauppinen S Delacourte A Strooper BD Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer’s disease correlates with increased BACE1/β-secretase expression PNAS 105 2008 6415 6420 18434550 PMC2359789
  75. [90]Vilardo E Barbato C Ciotti M Cogoni C Ruberti F MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons J Biol Chem 285 2010 18344 18351 20395292 PMC2881760
  76. [91]Wong HA Veremeyko T Patel N Lemere CA Walsh DM Esau C Vanderburg C Krichevsky AM De-repression of FOXO3a death axis by microRNA-132 and −212 causes neuronal apoptosis in Alzheimer’s disease Human Molecular Genetics 22 2013 3077 3092 23585551 PMC13387022
  77. [92]Dickson JR Kruse C Montagna DR Finsen B Wolfe MS Alternative polyadenylation and miR-34 family members regulate tau expression J Neurochem 127 2013 739 749 24032460 PMC3859707
  78. [93]Liu CG Song J Zhang YQ Wang PC MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer’s disease Mol Med Report 10 2014 2395 2400 25119742
  79. [94]Weinberg RB Mufson EJ Counts SE Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment Front Neurosci 9 2015 430 26594146 PMC4633499
  80. [95]Santa-Maria I Alaniz ME Renwick N Cela C Fulga TA Vactor DV Tuschl T Clark LN Shelanski ML McCabe BD Crary JF Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau J Clin Invest 125 2015 681 686 25574843 PMC4319412
  81. [96]Zhang B Chen CF Wang AH Lin QF MiR-16 regulates cell death in Alzheimer’s disease by targeting amyloid precursor protein Eur Rev Med Pharmacol Sci 19 2015 4020 4027 26592823
  82. [97]Zhang Y Xing H Guo S Zheng Z Wang H Xu D MicroRNA-135b has a neuroprotective role via targeting of β-site APP-cleaving enzyme 1 Exp Therap Med 12 2016 809 814 27446280 PMC4950157
  83. [98]Ghanbari M Ikram MA de Looper HW Hofman A Erkeland SJ Franco OH Dehghan A Genome-wide identification of microRNA-related variants associated with risk of Alzheimer’s disease Sci Rep 6 2016 28387 27328823 PMC4916596
  84. [99]Moncini S Lunghi M Valmadre A Grasso M Vescovo VD Riva P Denti MA Venturin M The miR-15/107 family of microRNA genes regulates CDK5R1/p35 with implications for Alzheimer’s disease pathogenesis Mol Neurobiol 2016 10.1007/s12035-016-0002-4 27343180 · DOI
  85. [100]Zhang C Lu J Liu B Cui Q Wang Y Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer’s disease Aging 8 2016 272 290 26856603 PMC4789582
  86. [101]Pereira PA Tomás JF Queiroz JA Figueiras AR Sousa F Recombinant pre-miR-29b for Alzheimer’s disease therapeutics Sci Rep 6 2016 19946 26818210 PMC4730146
  87. [102]Absalon S Kochanek DM Raghavan V Krichevsky AM MiR-26b, upregulated in Alzheimer’s disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons J Neurosci 33 2013 14645 14659 24027266 PMC3810537
  88. [103]Croce N Gelfo F Ciotti MT Federici G Caltagirone C Bernardini S Angelucci F NPY modulates miR-30a-5p and BDNF in opposite direction in an in vitro model of Alzheimer disease: a possible role in neuroprotection? Mol Cell Biochem 376 2013 189 195 23358924
  89. [104]Tian N Cao Z Zhang Y MiR-206 decreases brain-derived neurotrophic factor levels in a transgenic mouse model of Alzheimer’s disease Neurosci Bull 30 2014 191 197 24604632 PMC5562663
  90. [105]Banzhaf-Strathmann J Benito E May S Arzberger T Tahirovic S Kretzschmar H Fischer A Edbauer D MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer’s disease EMBO J 33 2014 1667 1680 25001178 PMC4194100
  91. [106]Sarkar S Jun S Rellick S Quintana DD Cavendish JZ Simpkins JW Expression of microRNA-34a in Alzheimer’s disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state Network activity Brain Research 1646 2016 139 151 27235866 PMC4975975
  92. [107]Kim W Noh H Lee Y Jeon J Shanmugavadivu A McPhie DL Kim KS Cohen BM Seo H Sonntag KC MiR-126 regulates growth factor activities and vulnerability to toxic insult in neurons Mol Neurobiol 53 2016 95 108 25407931 PMC4437970

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Sorted by citations

Authors
Reddy, P. H., Tonk, S., Kumar, S., Vijayan, M., Kandimalla, R., Kuruva, C. S., & Reddy, A. P.
Venue
Biochemical and Biophysical Research Communications
Publisher
Elsevier BV
Published
2017-02
Volume
483
Issue
4
Pages
1156-1165
ISSN
0006-291X
DOI
10.1016/j.bbrc.2016.08.067
PMC
PMC5343756
Cited by
119
References
14
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • NIH (AG042178, AG47812)
  • Garrison Family Foundation
  • Alzheimer's Association New Investigator Research Grant (2016-NIRG-39787)
  • Center of Excellence For Translational Neuroscience and Therapeutics grant number (PN-CTNT20115-AR)

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