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Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid

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Fatty acids regulation of inflammatory and metabolic genes

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Decreased Fatty Acid β-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice

Nakajima, T., Yang, Y., Lu, Y., Kamijo, Y., Yamada, Y., Nakamura, K., Koyama, M., Yamaguchi, S., Sugiyama, E., Tanaka, N., et al. (2017) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.242.229 · Cited by 26 · see citing works

n-3 Dietary supplementation and lipid metabolism: Differences between vegetable- and fish-derived oils

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Omega-3 fatty acids and metabolic partitioning of fatty acids within the liver in the context of nonalcoholic fatty liver disease

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Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation

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Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials

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Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice

Kimura, T., Nakajima, T., Kamijo, Y., Tanaka, N., Wang, L., Hara, A., Sugiyama, E., Tanaka, E., Gonzalez, F. J., & Aoyama, T. (2012) · PPAR Research · doi:10.1155/2012/174932 · Cited by 23 · see citing works

The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model

Jia, X., Naito, H., Yetti, H., Tamada, H., Kitamori, K., Hayashi, Y., Yamagishi, N., Wang, D., Yanagiba, Y., Ito, Y., et al. (2012) · Life Sciences · doi:10.1016/j.lfs.2012.04.029 · Cited by 21 · see citing works

Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact form

Nanthirudjanar, T., Furumoto, H., Hirata, T., & Sugawara, T. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-73 · Cited by 21 · see citing works

CAT‐2003: A novel sterol regulatory element‐binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3‐Leiden mice

Zimmer, M., Bista, P., Benson, E. L., Lee, D. W., Liu, F., Picarella, D., Vega, R. B., Vu, C. B., Yeager, M., Ding, M., et al. (2017) · Hepatology Communications · doi:10.1002/hep4.1042 · Cited by 20 · see citing works

Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function

Rijjal, D. A., Liu, Y., Lai, M., Song, Y., Danaei, Z., Wu, A., Mohan, H., Li, W., Schopfer, F. J., Dai, F. F., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102909 · Cited by 19 · see citing works

Small-molecule inhibitors of SREBP activation – potential for new treatment of metabolic disorders

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Controversies in the Use of Omega-3 Fatty Acids to Prevent Atherosclerosis

Quispe, R., Alfaddagh, A., Kazzi, B., Zghyer, F., Marvel, F. A., Blumenthal, R. S., Sharma, G., & Martin, S. S. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01031-9 · Cited by 17 · see citing works

Chronic ethanol consumption decreases serum sulfatide levels by suppressing hepatic cerebroside sulfotransferase expression in mice

Kanbe, H., Kamijo, Y., Nakajima, T., Tanaka, N., Sugiyama, E., Wang, L., Fang, Z., Hara, A., Gonzalez, F. J., & Aoyama, T. (2013) · Archives of Toxicology · doi:10.1007/s00204-013-1132-3 · Cited by 16 · see citing works

NUTRIGENÓMICA: REVELANDO LOS ASPECTOS MOLECULARES DE UNA NUTRICIÓN PERSONALIZADA

Julio Sanhueza, C., & Alfonso Valenzuela, B. (2012) · Revista chilena de nutrición · doi:10.4067/s0717-75182012000100008 · Cited by 16 · see citing works

Adipose-targeted SWELL1 deletion exacerbates obesity- and age-related nonalcoholic fatty liver disease

Gunasekar, S. K., Heebink, J., Carpenter, D. H., Kumar, A., Xie, L., Zhang, H., Schilling, J. D., & Sah, R. (2023) · JCI Insight · doi:10.1172/jci.insight.154940 · Cited by 14 · see citing works

SREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementation

Bouchard‐Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Përusse, L., & Vohl, M. (2014) · Lipids in Health and Disease · doi:10.1186/1476-511x-13-152 · Cited by 14 · see citing works

Anti-Inflammatory Activity of the Constituents from the Leaves of Perilla frutescens var. acuta

Youn, I. P., Han, S.-J., Jung, H. J., Noh, S. G., Chung, H. Y., Koo, Y. K., Shin, S., & Seo, E. K. (2023) · Pharmaceuticals · doi:10.3390/ph16121655 · Cited by 13 · see citing works

Dietary n-6:n-3 PUFA Ratio Modulates Inflammation-Related Gene Expression and Influences Improvements in Biochemical Parameters in a Murine Model of Diet-Induced Obesity

Gutierrez-Guerra, A., Cambrón-Mora, D., Rodriguez‐Echevarría, R., Hernández‐Bello, J., Campos-Perez, W. Y., Canales-Aguirre, A. A., Pérez-Robles, M., & Martínez‐López, E. (2025) · Nutrients · doi:10.3390/nu17121996 · Cited by 12 · see citing works

APOC3 rs2070667 Associates with Serum Triglyceride Profile and Hepatic Inflammation in Nonalcoholic Fatty Liver Disease

Xu, Q.-Y., Li, H., Cao, H., Pan, Q., & Fan, J. (2020) · BioMed Research International · doi:10.1155/2020/8869674 · Cited by 12 · see citing works

SREBP inhibitors: an updated patent review for 2008-present

Peng, Z., Chen, L., Wang, M., Yue, X., Wei, H., Xu, F., Hou, W., & Li, Y. (2023) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2023.2291393 · Cited by 12 · see citing works

Newly Identified Mechanisms of Total Parenteral Nutrition Related Liver Injury

Jain, A. K., & Teckman, J. H. (2014) · Advances in Hepatology · doi:10.1155/2014/621380 · Cited by 12 · see citing works

PPARα is down-regulated following liver transplantation in mice

Nakagawa, K., Tanaka, N., Morita, M., Sugioka, A., Miyagawa, S.-I., Gonzalez, F. J., & Aoyama, T. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2011.08.021 · Cited by 12 · see citing works

Black adzuki bean ( Vigna angularis ) extract exerts phenotypic effects on white adipose tissue and reverses liver steatosis in diet-induced obese mice

Kim, M. K., Pichiah, P. B. T., Kim, D. K., & Cha, Y. (2016) · Journal of Food Biochemistry · doi:10.1111/jfbc.12333 · Cited by 11 · see citing works

Attenuation of Kidney Injuries Maintains Serum Sulfatide Levels Dependent on Hepatic Synthetic Ability: A Possible Involvement of Oxidative Stress

Sheng, X., Nakajima, T., Wang, L., Zhang, X., Kamijo, Y., Takahashi, K., Tanaka, N., Sugiyama, E., Kyogashima, M., Aoyama, T., et al. (2012) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.227.1 · Cited by 9 · see citing works

A combination of dietary N-3 fatty acids and a cyclooxygenase-1 inhibitor attenuates nonalcoholic fatty liver disease in mice

Saraswathi, V., Perriotte‐Olson, C., Ganesan, M., Desouza, C. V., Alnouti, Y., Duryee, M. J., Thiele, G. M., Nordgren, T. M., & Clemens, D. L. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.01.011 · Cited by 9 · see citing works

Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet

Watanabe, S., & Tsuneyama, K. (2013) · The Journal of Toxicological Sciences · doi:10.2131/jts.38.379 · Cited by 7 · see citing works

Fish oil prevents excessive hepatic lipid accumulation without inducing oxidative stress

Hirako, S., Kim, H. J., Iizuka, Y., Nakasatomi, M., & Matsumoto, A. (2013) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2013.02.003 · Cited by 7 · see citing works

The Dietary Replacement of Soybean Oil by Canola Oil Does Not Prevent Liver Fatty Acid Accumulation and Liver Inflammation in Mice

Antunes, M. M., Godoy, G., Fernandes, I. D. L., Manin, L. P., Zappielo, C., Masi, L. N., de Oliveira, V. A. B., Visentainer, J. V., Curi, R., & Bazotte, R. B. (2020) · Nutrients · doi:10.3390/nu12123667 · Cited by 7 · see citing works

Dietary Omega-3 Fatty Acids from Fish and Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease in a Mediterranean Population: Findings from the NUTRIHEP Cohort

Tatoli, R., Bonfiglio, C., Donghia, R., Pesole, P. L., Fontana, L., & Giannelli, G. (2025) · Nutrients · doi:10.3390/nu17213372 · Cited by 5 · see citing works

Identification of Phenotypic Lipidomic Signatures in Response to Long Chain n‐3 Polyunsaturated Fatty Acid Supplementation in Humans

Picklo, M. J., Marcotte, B. V., Bukowski, M. R., de Toro‐Martín, J., RUST, B. M., Guénard, F., & Vohl, M. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.018126 · Cited by 5 · see citing works

Eryptosis in Liver Diseases: Contribution to Anemia and Hypercoagulation

Kurmangaliyeva, S. S., Baktikulova, K., Tkachenko, A. S., Seitkhanova, B., Tryfonyuk, L., Rakhimzhanova, F. S., Yussupov, R., & Kurmangaliyev, K. B. (2025) · Medical Sciences · doi:10.3390/medsci13030125 · Cited by 4 · see citing works

Supplementation with Fish Oil as a Source of n–3 Fatty Acids Does Not Downregulate Mammary Lipogenesis in Lactating Mice

Mahmoud, H., Harvatine, K. J., Boisclair Yves, R., & Bauman Dale, E. (2013) · Journal of Nutrition · doi:10.3945/jn.113.181149 · Cited by 4 · see citing works

Pharmacological and Toxicological Advances in PPAR-Related Medicines

Kamijo, Y., Nicol, C. J. B., & Alexson, S. E. H. (2012) · PPAR Research · doi:10.1155/2012/940964 · Cited by 4 · see citing works

Study protocol of a randomized controlled clinical trial investigating the effects of omega-3 supplementation on endothelial function, vascular structure, and metabolic parameters in adolescents with type 1 diabetes

Khorshidi, M., Sayyari, A., Olang, B., Alaei, M. R., Shab‐Bidar, S., Khalili, M., ‎Salehi, M., & Aryaeian, N. (2021) · Trials · doi:10.1186/s13063-021-05930-1 · Cited by 3 · see citing works

Lipids, Low-Grade Chronic Inflammation and NAFLD

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Ações do óleo de peixe e triglicerídeos de cadeia média na esteatose hepática e estresse oxidativo induzidos pela dieta hiperlipídica em ratos

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Hepatocyte PPARα Is Essential for Triglyceride-Lowering Effect of Pemafibrate

Zhang, Z., Zhang, X., Qian, C., Diao, P., Nakajima, T., Kimura, T., Gonzalez, F. J., & Tanaka, N. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27073308 · Cited by 1 · see citing works

The effects of different types of dietary fats in the liver

Sim, P. Y. (2012) · UPT. Syiah Kuala University Library (Syiah Kuala University) · Cited by 1 · see citing works

Mo1531 Hepatic Cerebroside Sulfotransferase is Induced by PPARα Activation in Mice

Kimura, T., Nakajima, T., Tanaka, N., Komatsu, M., Kamijo, Y., Tanaka, E. I., & Aoyama, T. (2012) · Gastroenterology · doi:10.1016/s0016-5085(12)63831-1

Génétique, acides gras oméga-3 et facteurs de risque des maladies cardiovasculaires

Bouchard‐Mercier, A. (2015) · Corpus Université Laval (Université Laval)

Nutritional Approach to Hepatobiliary Diseases

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El papel de los factores de transcripción en la regulación genética

Cabrera, G. B., Téllez-Delgadillo, J. E., & Fabela‐Illescas, H. E. (2023) · Inventio, la génesis de la cultura universitaria en Morelos · doi:10.30973/inventio/2022.18.46/4

BindingDB Entry 50047309: Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid.

BindingDB (2017) · UC San Diego · doi:10.7270/q2g162qt

Parâmetros do estresse oxidativo no soro de cães alimentados com rações suplementadas com óleo de caju, óleo de mamona e óleo de peixe

Ferreira, C. S. (2012) · Americanae (AECID Library)

Dietary Effects of Oxidized Eicosapentaenoic Acid (EPA) and Intact EPA on Hepatic Steatosis Induced by a High-sucrose Diet and Liver-X-receptor α Agonist in Mice

Furumoto, H., Nanthirudjanar, T., Hirata, T., & Sugawara, T. (2016) · Journal of Oleo Science · doi:10.5650/jos.ess15227

Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice

Kajikawa, S., Harada, T., Kawashima, A., Imada, K., & Mizuguchi, K. (2009) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2009.02.004 · Cited by 73 · see citing works

Mechanisms Mediating Effects of Eicosapentaenoic Acid in Hepatic Steatosis in High Fat Fed Mice and in HepG2 Hepatoma Cells

Gonzalez, S., Albracht‐Schulte, K., Ramalingam, L., Kalupahana, N. S., & Moustaïd‐Moussa, N. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.646.53 · Cited by 2 · see citing works

エイコサペンタエン酸は非アルコール性脂肪性肝炎を改善する

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Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice

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