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Cited by 292

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing

Open access
Liu, Yunhang, Xu, Bolong, Lu, Mingzhu, Li, Shanshan, Guo, Juan, Chen, Fangzhou, Xiong, Xiaolu, Yin, Zhe, Liu, Huiyu, Zhou, Dongsheng·2022·Bioactive Materials

Abstract

Pathogenic bacteria pose a devastating threat to public health. However, because of the growing bacterial antibiotic resistance, there is an urgent need to develop alternative antibacterial strategies to the established antibiotics. Herein, iron-doped carbon dots (Fe-CDs, ∼3 nm) nanozymes with excellent photothermal conversion and photoenhanced enzyme-like properties are developed through a facile one-pot pyrolysis approach for synergistic efficient antibacterial therapy and wound healing. In particular, Fe doping endows CDs with photoenhanced peroxidase (POD)-like activity, which lead to the generation of heat and reactive oxygen species (ROS) for Gram-positive and Gram-negative bacteria killing. This study demonstrates Fe-CDs have significant wound healing efficiency of Fe-CDs by preventing infection, promoting fibroblast proliferation, angiogenesis, and collagen deposition. Furthermore, the ultrasmall size of Fe-CDs possesses good biocompatibility favoring clinical translation. We believe that the nanozyme-mediated therapeutic platform presented here is expected to show promising applications in antibacterial.

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Metadata

Authors
Liu, Y., Xu, B., Lu, M., Li, S., Guo, J., Chen, F., Xiong, X., Yin, Z., Liu, H., & Zhou, D.
Venue
Bioactive Materials
Publisher
Elsevier BV
Published
2022-06
Volume
12
Pages
246-256
ISSN
  • 2097-1192 (ISSN-L)
  • 2452-199X
OpenAlex
W3209913821
Cited by
292
References
49
FWCI
12.44
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing. https://app.cochat.ai/papers/10.1016/j.bioactmat.2021.10.023
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Liu, Y., Xu, B., Lu, M., Li, S., Guo, J., Chen, F., Xiong, X., Yin, Z., Liu, H., & Zhou, D. (2022). Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing. Bioactive Materials. https://doi.org/10.1016/j.bioactmat.2021.10.023

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