The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors
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“Amyloid aggregates caused by TP53 mutations have been found in biopsy specimens from ovarian and breast cancers.484,485”
From Targeting p53 pathways: mechanisms, structures, and advances in therapy (2023) · cites this paper as [484]
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Citations
Cites
Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607
TP53 mutations in human cancers: origins, consequences, and clinical use.
Olivier, M., Hollstein, M., & Hainaut, P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001008 · Cited by 2,199 · cited 3×
“Around 90% of the mutations are located at the central DNA-binding domain (Petitjean et al., 2007; Olivier et al., 2010).”
BackgroundTP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes
Petitjean, A., Achatz, M. I. W., Borresen-Dale, A. L., Hainaut, P., & Olivier, M. (2007) · Oncogene · doi:10.1038/sj.onc.1210302 · Cited by 884
p53 isoforms can regulate p53 transcriptional activity
Bourdon, J.-C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K., & Lane, D. P. (2005) · Genes & Development · doi:10.1101/gad.1339905 · Cited by 810
Structural Classification of Toxic Amyloid Oligomers
Glabe, C. G. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r800016200 · Cited by 783
The complexity of p53 stabilization and activation
Lavin, M. F., & Gueven, N. (2006) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4401925 · Cited by 701
Research works printed but not linked: 17
- Ano Bom, 2009, The p53 core domain is a molten globule at low pH: functional implications of an intrinsically partially unfolded structure, J Biol Chem, 285, 2857, 10.1074/jbc.M109.075861 · DOI
- Courtois, 2004, P53 protein variants: structural and functional similarities with p63 and p73 isoforms, Oncogene, 23, 631, 10.1038/sj.onc.1206929 · DOI
- Elston, 1991, Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up, Histopathology, 19, 403, 10.1111/j.1365-2559.1991.tb00229.x · DOI · Paper page
- Glabe, 2004, Conformation-dependent antibodies target diseases of protein misfolding, Trends Biochem Sci, 29, 542, 10.1016/j.tibs.2004.08.009 · DOI
- Higashimoto, 2006, Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer, Biochemistry, 45, 1608, 10.1021/bi051192j · DOI · Paper page
- Ishimaru, 2003, Fibrillar aggregates of the tumor suppressor p53 core domain, Biochemistry, 42, 9022, 10.1021/bi034218k · DOI · Paper page
- Ishimaru, 2004, Reversible aggregation plays a crucial role on the folding landscape of p53 core domain, Biophys J, 87, 2691, 10.1529/biophysj.104.044685 · DOI
- Ishimaru, 2009, Cognate DNA stabilizes the tumor suppressor p53 and prevents misfolding and aggregation, Biochemistry, 48, 6126, 10.1021/bi9003028 · DOI
- Langer⊘d, 2007, TP53 mutation status and gene expression profiles are powerful prognostic markers of breast, Breast Cancer Res, 9, R30, 10.1186/bcr1675 · DOI · Paper page
- Lee, 2003, Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant, J Mol Biol, 327, 699, 10.1016/S0022-2836(03)00175-X · DOI
- Oren, 2010, Mutant p53 gain-of-function in cancer, Cold Spring Harb Perspect Biol, 2, a001107, 10.1101/cshperspect.a001107 · DOI · Paper page
- Olivier, 2006, The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer, Clin Cancer Res, 12, 1157, 10.1158/1078-0432.CCR-05-1029 · DOI · Paper page
- Rigacci, 2008, The (1–63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies, Biophys J, 94, 3635, 10.1529/biophysj.107.122283 · DOI
- Sanchez-Ruiz, 2010, Protein kinetic stability, Biophys Chem, 148, 1, 10.1016/j.bpc.2010.02.004 · DOI · Paper page
- Silva, 2010, Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor protein, Acc Chem Res, 43, 271, 10.1021/ar900179t · DOI
- Simao, 2002, TP53 mutations in breast cancer tumors of patients from Rio de Janeiro Brazil: association with risk factors and tumor characteristics, Int J Cancer, 101, 69, 10.1002/ijc.10567 · DOI
- Uversky, 2010, Mysterious oligomerization of the amyloidogenic proteins, FEBS J, 2940, 10.1111/j.1742-4658.2010.07721.x · DOI · Paper page
Cited by
Targeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
Targeting mutant p53 for efficient cancer therapy
Bykov, V. J. N., Eriksson, S. E., Bianchi, J., & Wiman, K. G. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.109 · Cited by 889
A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas
Soragni, A., Janzen, D. M., Johnson, L. M., Lindgren, A. G., Thai-Quynh Nguyen, A., Tiourin, E., Soriaga, A. B., Lu, J., Jiang, L., Faull, K. F., et al. (2016) · Cancer Cell · doi:10.1016/j.ccell.2015.12.002 · Cited by 341
(2019) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2019.08.002 · Cited by 78
Self-citation
Metadata
- Authors
- Levy, C. B., Stumbo, A. C., Ano Bom, A. P. D., Portari, E. A., Carneiro, Y., Silva, J. L., & De Moura-Gallo, C. V.
- Venue
- The International Journal of Biochemistry & Cell Biology
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 43
- Issue
- 1
- Pages
- 60-64
- ISSN
- 1357-2725
- Cited by
- 144
- References
- 6
- Language
- en
- Update notices
- erratum (2011-06-01)
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
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- CoChat. (2026). Citation check: Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors. https://app.cochat.ai/papers/10.1016/j.biocel.2010.10.017
- The paper
- Levy, C. B., Stumbo, A. C., Ano Bom, A. P. D., Portari, E. A., Carneiro, Y., Silva, J. L., & De Moura-Gallo, C. V. (2011). Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors. The International Journal of Biochemistry & Cell Biology. https://doi.org/10.1016/j.biocel.2010.10.017
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
