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Cited by 469

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy

Open access
Li, Jingchao, Rao, Jianghong, Pu, Kanyi·2018·Biomaterials

Abstract

As a new class of organic optical nanomaterials, semiconducting polymer nanoparticles (SPNs) have the advantages of excellent optical properties, high photostability and facile surface functionalization, and are considered to possess good biocompatibility for biomedical applications. This review surveys recent progress made on the design and synthesis of SPNs for molecular imaging and cancer phototherapy. A variety of novel polymer design, chemical modification and nanoengineering strategies have been developed to precisely tune up optoelectronic properties of SPNs to enable fluorescence, chemiluminescence and photoacoustic (PA) imaging in living animals. With these imaging modalities, SPNs have been demonstrated not only to image tissues such as lymph nodes, vascular structure and tumors, but also to detect disease biomarkers such as reactive oxygen species (ROS) and protein sulfenic acid as well as physiological indexes such as pH and blood glucose concentration. The potentials of SPNs in cancer phototherapy including photodynamic and photothermal therapy are also highlighted with recent examples. Future efforts should further expand the use of SPNs in biomedical research and may even move them beyond pre-clinical studies.

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Metadata

Authors
Li, J., Rao, J., & Pu, K.
Venue
Biomaterials
Publisher
Elsevier BV
Published
2018-02
Volume
155
Pages
217-235
ISSN
0142-9612 (ISSN-L)
OpenAlex
W2769897287
Cited by
469
References
9
FWCI
26.31
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy. https://app.cochat.ai/papers/10.1016/j.biomaterials.2017.11.025
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Li, J., Rao, J., & Pu, K. (2018). Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy. Biomaterials. https://doi.org/10.1016/j.biomaterials.2017.11.025

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.