Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

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Burden of major musculoskeletal conditions.

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Osteoarthritis: an update with relevance for clinical practice

Bijlsma, J. W. J., Berenbaum, F., & Lafeber, F. P. J. G. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60243-2 · Cited by 2,301

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

Tian, Y., Li, S., Song, J., Ji, T., Zhu, M., Anderson, G. J., Wei, J., & Nie, G. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.083 · Cited by 1,841

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

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Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges

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A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

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Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

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Engineering exosomes for targeted drug delivery

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Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

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Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

Duan, L., Ouyang, K., Xu, X., Xu, L., Wen, C., Zhou, X., Qin, Z., Xu, Z., Sun, W., & Liang, Y. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.673286 · Cited by 377

Exosome engineering in cell therapy and drug delivery

Sadeghi, S., Tehrani, F. R., Tahmasebi, S., Shafiee, A., & Hashemi, S. M. (2023) · Inflammopharmacology · doi:10.1007/s10787-022-01115-7 · Cited by 351

VH298-loaded extracellular vesicles released from gelatin methacryloyl hydrogel facilitate diabetic wound healing by HIF-1α-mediated enhancement of angiogenesis

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Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment

Liang, Y., Xu, X., Xu, L., Iqbal, Z., Ouyang, K., Zhang, H., Wen, C., Duan, L., & Xia, J. (2022) · Theranostics · doi:10.7150/thno.69368 · Cited by 217

Targeted therapy using engineered extracellular vesicles: principles and strategies for membrane modification

Liu, Q., Li, D., Pan, X., & Liang, Y. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02081-0 · Cited by 201

Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome‐Conjugated Magnetic Nanoparticles for Glioblastoma Therapy

Li, B., Chen, X., Qiu, W., Zhao, R., Duan, J., Zhang, S., Pan, Z., Zhao, S., Guo, Q., Qi, Y., et al. (2022) · Advanced Science · doi:10.1002/advs.202105451 · Cited by 204

Nucleic acid drugs: recent progress and future perspectives

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Ultra-durable cell-free bioactive hydrogel with fast shape memory and on-demand drug release for cartilage regeneration

Yang, Y., Zhao, X., Wang, S., Zhang, Y., Yang, A., Cheng, Y., & Chen, X. (2023) · Nature Communications · doi:10.1038/s41467-023-43334-8 · Cited by 182

Harnessing Tissue-derived Extracellular Vesicles for Osteoarthritis Theranostics

Yin, B., Ni, J., Witherel, C. E., Yang, M., Burdick, J. A., Wen, C., & Wong, S. H. D. (2021) · Theranostics · doi:10.7150/thno.62708 · Cited by 168

Targeting strategies for bone diseases: signaling pathways and clinical studies

Xu, H., Wang, W., Liu, X., Huang, W. H., Chen, Z., Xu, Y., Yang, H., Bai, J., & Geng, D. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01467-8 · Cited by 177

Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis

Xiang, X.-N., Zhu, S., He, H., Yu, X. Y., Xu, Y. Y., & He, C. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02689-9 · Cited by 168

Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage

Zhou, H., Shen, X., Chen, Y., Wu, X., Ma, Z., Tan, Z., Wang, J., Li, Y., Liu, J., Duan, A., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03005-9 · Cited by 170

Cell-free exosome-laden scaffolds for tissue repair

Huang, J., Xiong, J., Yang, L., Zhang, J., Sun, S., & Liang, Y. (2021) · Nanoscale · doi:10.1039/d1nr01314a · Cited by 152

Research progress in the use of mesenchymal stem cells and their derived exosomes in the treatment of osteoarthritis

Yu, H., Huang, Y., & Yang, L. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101684 · Cited by 151

Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2

Liu, W., Tang, P., Wang, J., Wu, Y., Ge, X., Rong, Y., Ji, C., Wang, Z., Bai, J., Fan, J., et al. (2021) · Journal of Pineal Research · doi:10.1111/jpi.12769 · Cited by 148

Exosome for mRNA delivery: Strategies and therapeutic applications

Iqbal, Z., Rehman, K., Mahmood, A., Shabbir, M., Liang, Y., Duan, L., & Zeng, H. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02634-x · Cited by 144

Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke

Zhu, Z.-H., Jia, F., Ahmed, W., Zhang, G.-L., Wang, H., Lin, C.-Q., Chen, W.-H., & Chen, L.-K. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.346466 · Cited by 132

Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy

Wan, J., He, Z., Peng, R., Wu, X., Zhu, Z., Cui, J., Hao, X., Chen, A., Zhang, J., & Cheng, P. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02050-7 · Cited by 138

Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment

Wen, C., Xu, L., Xu, X. G., Wang, D., Liang, Y., & Duan, L. (2021) · Arthritis Research & Therapy · doi:10.1186/s13075-021-02662-0 · Cited by 130

Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy

Lin, Y., Yan, M., Bai, Z., Xie, Y., Ren, L., Wei, J., Zhu, D., Wang, H., Liu, Y., Luo, J., et al. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01636-x · Cited by 125

Targeted treatment for osteoarthritis: drugs and delivery system

Mao, L., Wu, W., Wang, M., Guo, J., Li, H., Zhang, S., Xu, J., & Zou, J. (2021) · Drug Delivery · doi:10.1080/10717544.2021.1971798 · Cited by 123

Thermosensitive Hydrogel Loaded with Primary Chondrocyte-Derived Exosomes Promotes Cartilage Repair by Regulating Macrophage Polarization in Osteoarthritis

Sang, X., Zhao, X., Yan, L., Jin, X. Y., Wang, X., Wang, J., Yin, Z., Zhang, Y., & Meng, Z. (2022) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-022-00437-5 · Cited by 111

The Therapeutic Potential and Clinical Significance of Exosomes as Carriers of Drug Delivery System

Li, T., Li, X., Han, G., Liang, M., Yang, Z., Zhang, C., Huang, S., Tai, S., & Yu, S. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010021 · Cited by 110

Regeneration of articular cartilage defects: Therapeutic strategies and perspectives

Guo, X., Xi, L., Yu, M., Fan, Z., Wang, W., Ju, A., Liang, Z., Zhou, G., & Ren, W. (2023) · Journal of Tissue Engineering · doi:10.1177/20417314231164765 · Cited by 110

Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in osteoarthritis

Zhao, S., Xiu, G., Wang, J., Wen, Y., Lu, J., Wu, B., Wang, G., Yang, D., Ling, B., Du, D., et al. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02086-9 · Cited by 109

Nanoarchitectonics of Cartilage-Targeting Hydrogel Microspheres with Reactive Oxygen Species Responsiveness for the Repair of Osteoarthritis

Han, Y., Huang, C., Kong, X., Ma, J., Ren, P., Chen, J., Zhang, X., Luo, H., & Chen, G. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c12703 · Cited by 109

Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy

Liu, W., Liu, A., Li, X., Sun, Z., Sun, Z., Liu, Y., Wang, G., Huang, D., Xiong, H., Yu, S., et al. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.06.012 · Cited by 107

Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy

Li, F., Wu, J., Li, D., Hao, L., Li, Y., Yi, D., Yeung, K. W. K., Chen, D., Lu, W. W., Pan, H., et al. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01347-3 · Cited by 99

Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Liu, Z., Zhuang, Y., Fang, L., Yuan, C., Wang, X., & Lin, K. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.10.012 · Cited by 103

Immunomodulatory Mechanisms and Therapeutic Potential of Mesenchymal Stem Cells

Yang, G., Fan, X., Liu, Y., Jie, P., Mazhar, M., Liu, Y., Dechsupa, N., & Wang, L. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10539-9 · Cited by 113

3D Bioprinting of Hydrogels for Cartilage Tissue Engineering

Huang, J., Xiong, J., Wang, D., Zhang, J., Yang, L., Sun, S., & Liang, Y. (2021) · Gels · doi:10.3390/gels7030144 · Cited by 98

Self‐Reinforced MOF‐Based Nanogel Alleviates Osteoarthritis by Long‐Acting Drug Release

Sun, Y., Ding, S., Zhao, X., Sun, D., Yang, Y., Chen, M., Zhu, C., Jiang, B., Gu, Q., Liu, H., et al. (2024) · Advanced Materials · doi:10.1002/adma.202401094 · Cited by 96

Nanoengineering facilitating the target mission: targeted extracellular vesicles delivery systems design

Song, H., Chen, X., Hao, Y., Wang, J., Xie, Q., & Wang, X. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01638-9 · Cited by 98

Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy

Liu, H., Geng, Z., & Su, J. (2022) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2022.04 · Cited by 95

Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases

Wang, C., Xu, M., Fan, Q., Li, C., & Zhou, X. (2022) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2022.100772 · Cited by 91

Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration

Luo, L., Gong, J., Wang, Z., Liu, Y., Cao, J., Qin, J., Zuo, R. M., Zhang, H., Wang, S., Zhao, P., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.12.007 · Cited by 91

Knee Osteoarthritis Therapy: Recent Advances in Intra-Articular Drug Delivery Systems

Ma, L., Zheng, X., Lin, R., Sun, A. R., Song, J., Ye, Z., Liang, D., Zhang, M., Tian, J. H., Zhou, X., et al. (2022) · Drug Design Development and Therapy · doi:10.2147/dddt.s357386 · Cited by 86

Dapagliflozin‐Loaded Exosome Mimetics Facilitate Diabetic Wound Healing by HIF‐1 α ‐Mediated Enhancement of Angiogenesis

Zhang, W., Wang, L., Guo, H., Chen, L., & Huang, X. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202202751 · Cited by 84

Kartogenin‐Conjugated Double‐Network Hydrogel Combined with Stem Cell Transplantation and Tracing for Cartilage Repair

Chen, Y., Yan, X., Yuan, F., Lin, L., Wang, S., Ye, J., Zhang, J., Yang, M., Wu, D., Wang, X., et al. (2022) · Advanced Science · doi:10.1002/advs.202105571 · Cited by 82

Engineering exosomes and exosome-like nanovesicles for improving tissue targeting and retention

Li, L., Wang, F., Zhu, D., Hu, S., Cheng, K., & Li, Z. (2024) · Fundamental Research · doi:10.1016/j.fmre.2024.03.025 · Cited by 87

Exosomes Derived From Kartogenin-Preconditioned Mesenchymal Stem Cells Promote Cartilage Formation and Collagen Maturation for Enthesis Regeneration in a Rat Model of Chronic Rotator Cuff Tear

Cai, J., Xu, J., Ye, Z., Wang, L., Zheng, T., Zhang, T., Li, Y., Jiang, J., & Zhao, J. (2023) · The American Journal of Sports Medicine · doi:10.1177/03635465231155927 · Cited by 81

Functional Extracellular Vesicles for Regenerative Medicine

Kim, H. Y., Kwon, S., Um, W., Shin, S., Kim, C. H., Park, J. H., & Kim, B. (2022) · Small · doi:10.1002/smll.202106569 · Cited by 81

Engineered bacterial extracellular vesicles for osteoporosis therapy

Liu, H., Li, M., Zhang, T., Liu, X., Zhang, H., Geng, Z., & Su, J. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.138309 · Cited by 78

Bone-targeted bioengineered bacterial extracellular vesicles delivering siRNA to ameliorate osteoporosis

Liu, H., Zhang, H., Wang, S., Cui, J., Weng, W., Liu, X., Tang, H., Hu, Y., Li, X., Zhang, K., et al. (2023) · Composites Part B Engineering · doi:10.1016/j.compositesb.2023.110610 · Cited by 78

Relieving Macrophage Dysfunction by Inhibiting SREBP2 Activity: A Hypoxic Mesenchymal Stem Cells‐Derived Exosomes Loaded Multifunctional Hydrogel for Accelerated Diabetic Wound Healing

Shi, Y., Wang, S., Wang, K., Yang, R., Liu, D., Liao, H., Qi, Y., Qiu, K., Hu, Y., Wen, H., et al. (2024) · Small · doi:10.1002/smll.202309276 · Cited by 76

Plant-derived exosomal nanoparticles: potential therapeutic for inflammatory bowel disease

Li, D., Tang, Q., Yang, M., Xu, H., Zhu, M., Zhang, Y., Tian, C., Nie, Y., Wang, J., Liang, Y., et al. (2023) · Nanoscale Advances · doi:10.1039/d3na00093a · Cited by 81

Cell-derived extracellular vesicles for CRISPR/Cas9 delivery: engineering strategies for cargo packaging and loading

Liang, Y., Iqbal, Z., Wang, J., Xu, L., Xu, X., Ouyang, K., Zhang, H., Lu, J., Duan, L., & Xia, J. (2022) · Biomaterials Science · doi:10.1039/d2bm00480a · Cited by 72

Curcumin primed ADMSCs derived small extracellular vesicle exert enhanced protective effects on osteoarthritis by inhibiting oxidative stress and chondrocyte apoptosis

Xu, C., Zhai, Z., Ying, H., Lü, L., Zhang, J., & Zeng, Y. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01339-3 · Cited by 72

Nanomaterials for mRNA ‐based therapeutics: Challenges and opportunities

Li, D., Liu, Q., Yang, M., Xu, H., Zhu, M., Zhang, Y., Xu, J., Tian, C., Yao, J., Wang, L., et al. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10492 · Cited by 74

Exosomes as Rheumatoid Arthritis Diagnostic Biomarkers and Therapeutic Agents

Heydari, R., Koohi, F., Rasouli, M., Rezaei, K., Abbasgholinejad, E., Bekeschus, S., & Doroudian, M. (2023) · Vaccines · doi:10.3390/vaccines11030687 · Cited by 71

Engineered Extracellular Vesicles as a Targeted Delivery Platform for Precision Therapy

Sun, Y., Sun, F., Xu, W., & Qian, H. (2023) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-022-00503-y · Cited by 73

Current strategies in tailoring methods for engineered exosomes and future avenues in biomedical applications

Mishra, A., Singh, P., Qayoom, I., Prasad, A., & Kumar, A. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb01088c · Cited by 70

Engineering of MSC-Derived Exosomes: A Promising Cell-Free Therapy for Osteoarthritis

Cheng, J., Sun, Y., Ma, Y., Ao, Y., Hu, X., & Meng, Q. (2022) · Membranes · doi:10.3390/membranes12080739 · Cited by 69

Mesenchymal Stem Cell Exosomes Encapsulated Oral Microcapsules for Acute Colitis Treatment

Gan, J., Sun, L., Chen, G., Ma, W., Zhao, Y., & Sun, L. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202201105 · Cited by 68

Recent development in multizonal scaffolds for osteochondral regeneration

Yu, L., Cavelier, S., Hannon, B., & Wei, M. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.01.012 · Cited by 66

Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation Strategies

Jiang, X., Li, W., Ge, L., & Lü, M. (2023) · Aging and Disease · doi:10.14336/ad.2023.0208 · Cited by 70

Osteoclast-targeted delivery of anti-miRNA oligonucleotides by red blood cell extracellular vesicles

Xu, L., Xu, X., Liang, Y., Wen, C., Ouyang, K., Huang, J., Xiao, Y., Deng, X., Xia, J., & Duan, L. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.04.043 · Cited by 65

Exosomes in osteoarthritis: Updated insights on pathogenesis, diagnosis, and treatment

Fan, W.-J., Liu, D., Pan, L., Wang, W., Ding, Y., Zhang, Y.-Y., Ye, R., Zhou, Y., An, S., & Xiao, W. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.949690 · Cited by 67

Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis

Luo, D., Zhu, H., Li, S., Wang, Z., & Xiao, J. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1309946 · Cited by 69

Preparation of epigallocatechin gallate decorated Au-Ag nano-heterostructures as NIR-sensitive nano-enzymes for the treatment of osteoarthritis through mitochondrial repair and cartilage protection

Xu, S., Chang, L., Zhao, X., Hu, Y., Lin, Y., Chen, Z., Ren, X., & Mei, X. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.03.038 · Cited by 63

Emerging role of bacterial outer membrane vesicle in gastrointestinal tract

Tian, C., Yang, M., Xu, H., Zhu, M., Zhang, Y., Yao, J., Wang, L., Liang, Y.-J., & Li, D. (2023) · Gut Pathogens · doi:10.1186/s13099-023-00543-2 · Cited by 63

Advances in Extracellular-Vesicles-Based Diagnostic and Therapeutic Approaches for Ocular Diseases

Su, Y., Chen, M., Xu, W., Gu, P., & Fan, X. (2024) · ACS Nano · doi:10.1021/acsnano.4c08486 · Cited by 61

Retuning Mitochondrial Apoptosis/Mitophagy Balance via SIRT3‐Energized and Microenvironment‐Modulated Hydrogel Microspheres to Impede Osteoarthritis

Xia, X., Liu, Y., Lu, Y., Liu, J., Deng, Y., Wu, Y., Hou, M., He, F., Yang, H., Xu, Y. X., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202302475 · Cited by 59

Advanced Nanocomposite Hydrogels for Cartilage Tissue Engineering

Huang, J., Liu, F., Su, H., Xiong, J., Yang, L., Xia, J., & Liang, Y. (2022) · Gels · doi:10.3390/gels8020138 · Cited by 58

Synergistic chondrogenesis promotion and arthroscopic articular cartilage restoration via injectable dual-drug-loaded sulfated hyaluronic acid hydrogel for stem cell therapy

Gao, W. L., Chen, K., He, W., Zhao, S., Cui, D., Tao, C., Xu, Y., Xiao, X., Feng, Q., & Xia, H. (2023) · Composites Part B Engineering · doi:10.1016/j.compositesb.2023.110857 · Cited by 58

Charge‐Reversed Exosomes for Targeted Gene Delivery to Cartilage for Osteoarthritis Treatment

Zhang, C., Pathrikar, T. V., Baby, H. M., Li, J., Zhang, H., Selvadoss, A., Ovchinnikova, A., Ionescu, A. M., Chubinskaya, S., Miller, R. E., et al. (2024) · Small Methods · doi:10.1002/smtd.202301443 · Cited by 59

Tissue Engineering and Regenerative Medicine: Perspectives and Challenges

Hoang, V. T., Nguyen, Q. T., Phan, T. T. K., Pham, T. H., Dinh, N. T. H., Anh, L. P. H., Dao, L. T. M., Bui, V. D., Dao, H., Le, D. S., et al. (2025) · MedComm · doi:10.1002/mco2.70192 · Cited by 67

Optimization of exosome-based cell-free strategies to enhance endogenous cell functions in tissue regeneration

Deng, S., Cao, H., Cui, X., Fan, Y., Wang, Q., & Zhang, X. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.09.023 · Cited by 60

Bone Targeting Nanoparticles for the Treatment of Osteoporosis

Wen, C., Xu, X. M., Zhang, Y., Xia, J., Liang, Y., & Xu, L. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s444347 · Cited by 58

Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications

Liang, Y.-J., Xu, X., Xu, L., Prasadam, I., Duan, L., Xiao, Y., & Xia, J. (2020) · Journal of drug targeting (Print) · doi:10.1080/1061186x.2020.1870231 · Cited by 46

Engineering Approaches for Exosome Cargo Loading and Targeted Delivery: Biological versus Chemical Perspectives

Ahmed, W., Mushtaq, A., Ali, S., Khan, N., Liang, Y., & Duan, L. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c00856 · Cited by 56

Spatiotemporal regulation of endogenous MSCs using a functional injectable hydrogel system for cartilage regeneration

Dong, Y., Liu, Y., Chen, Y., Sun, X., Zhang, L., Zhang, Z., Wang, Y., Qi, C., Wang, S., & Yang, Q. (2021) · NPG Asia Materials · doi:10.1038/s41427-021-00339-3 · Cited by 53

Engineered Extracellular Vesicles: A potential treatment for regeneration

Cheng, W., Xu, C., Su, Y., Shen, Y., Yang, Q., Zhao, Y., Zhao, Y., & Liu, Y. (2023) · iScience · doi:10.1016/j.isci.2023.108282 · Cited by 56

Engineering preparation and sustained delivery of bone functional exosomes-laden biodegradable hydrogel for in situ bone regeneration

Sun, J., Li, G., Wu, S., Zou, Y., Weng, W., Gai, T., Chen, X., Zhang, K., Zhou, F., Wang, X., et al. (2023) · Composites Part B Engineering · doi:10.1016/j.compositesb.2023.110803 · Cited by 53

Extracellular vesicles-loaded DNA hydrogels: A promising candidate for cartilage organoids engineering

Ma, Z., Wu, Y., Li, G., Liu, J., Geng, Z., & Su, J. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.147146 · Cited by 51

Nanomedicines Promote Cartilage Regeneration in Osteoarthritis by Synergistically Enhancing Chondrogenesis of Mesenchymal Stem Cells and Regulating Inflammatory Environment

Cui, S.-H., Yan, Y., Lu, A., Dou, Y., Li, Z.-X., Zhu, Z.-H., Du, M.-Z., Zhu, Y., Chen, X., Wang, X., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c11848 · Cited by 51

Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy

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