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Exosome engineering in cell therapy and drug delivery
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“Therefore, developing cost-effective and scalable production methods is essential for advancing the clinical application of exosome-based therapies [6].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [6]
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“One of the most significant benefits is the high biocompatibility and low immunogenicity of exosomes, which originate from the body’s own cells. This minimizes the risk of immune reactions, making them an ideal carrier for delivering treatments to cancer patients, who often have weakened immune systems [6].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [6]
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The biology , function , and biomedical applications of exosomes
Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770
Principles of nanoparticle design for overcoming biological barriers to drug delivery
Blanco, E., Shen, H., & Ferrari, M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3330 · Cited by 7,002 · cited 2×
“Therefor, by optimizing the surface charge, the targeting efficiency of exosome could be controled toward the desired organs (Blanco et al. 2015).”
BackgroundExosomes: biogenesis, biologic function and clinical potential
Zhang, Y., Liu, Y., Liu, H., & Tang, W. H. (2019) · Cell & Bioscience · doi:10.1186/s13578-019-0282-2 · Cited by 2,119
Engineering exosomes for targeted drug delivery
Liang, Y., Duan, L., Lu, J., & Xia, J. (2021) · Theranostics · doi:10.7150/thno.52570 · Cited by 1,547
Ha, D., Yang, N., & Nadithe, V. (2016) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2016.02.001 · Cited by 1,346
Zhang, Y., Bi, J., Huang, J., Tang, Y., Du, S., & Li, P. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s264498 · Cited by 1,323
Surface Functionalization of Exosomes Using Click Chemistry
Smyth, T., Petrova, K., Payton, N. M., Persaud, I., Redzic, J. S., Graner, M. W., Smith-Jones, P., & Anchordoquy, T. J. (2014) · Bioconjugate Chemistry · doi:10.1021/bc500291r · Cited by 532
Exosome engineering: Current progress in cargo loading and targeted delivery
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Liang, Y., Xu, X., Li, X., Xiong, J., Li, B., Duan, L., Wang, D., & Xia, J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c10458 · Cited by 391
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Cited by
Sorted by citations
Emerging role of exosomes in cancer therapy: progress and challenges
Li, J., Wang, J., & Chen, Z. (2025) · Molecular Cancer · doi:10.1186/s12943-024-02215-4 · Cited by 297
Metadata
- Authors
- Sadeghi, S., Tehrani, F. R., Tahmasebi, S., Shafiee, A., & Hashemi, S. M.
- Venue
- Inflammopharmacology
- Published
- 2023-01-07
- Volume
- 31
- Issue
- 1
- Pages
- 145-169
- ISSN
- 0925-4692
- 1568-5608
- PMC
- PMC9823267
- Cited by
- 351
- References
- 13
- Language
- en
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