Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection

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Ongoing Use of SSRIs Does Not Alter Outcome in Hospitalized COVID-19 Patients: A Retrospective Analysis

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A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.

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Periodontal and peri-implant status and whole salivary interleukin 1-beta levels among individuals using selective serotonin reuptake inhibitors: an observational study

ALHarthi, S. S., BinShabaib, M. S., Alwahibi, A., Gamal, S., Elashiry, E., Almershed, S. E., Alkhamis, H. A., & Anweigi, L. M. (2023) · BMC Oral Health · doi:10.1186/s12903-023-02908-0 · Cited by 9 · see citing works

Selective serotonin reuptake inhibitors: New hope in the fight against COVID-19

Anar, M. A., Foroughi, E., Sohrabi, E., Peiravi, S., Tavakoli, Y., Khouzani, M. K., Behshood, P., Shamshiri, M., Faridzadeh, A., Keylani, K., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1036093 · Cited by 11 · see citing works

COVID-19 and its clinical severity are associated with alterations of plasma sphingolipids and enzyme activities of sphingomyelinase and ceramidasePreprint

Mühle, C., Kremer, A. E., Vetter, M., Schmid, J., Achenbach, S., Schumacher, F., Lenz, B., Cougoule, C., Hoertel, N., Carpinteiro, A., et al. (2022) · medRxiv · doi:10.1101/2022.01.19.22269391 · Cited by 8 · see citing works

Antidepressants and the Risk of Psoriasis Induction: A Case–Control Study

Sadatmadani, S.-F., Siadat, A. H., Iraji, F., & Alsahebfosoul, F. (2023) · Advanced Biomedical Research · doi:10.4103/abr.abr_88_21 · Cited by 7 · see citing works

Effect of mechanical instrumentation with adjunct photodynamic therapy on salivary TNFα levels and clinical periodontal and peri‑implant status in patients with depression: A randomized controlled trial

ALHarthi, S. S., Divakar, D. D., Alwahibi, A., & BinShabaib, M. S. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103042 · Cited by 6 · see citing works

Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons

Huang, Y., Michalski, C., Zhou, Y., Xu, C., Niu, W., Lucido, M. J., Wang, J., Feng, Y., Miller, A. H., & Wen, Z. (2026) · Neuropsychopharmacology · doi:10.1038/s41386-025-02320-y · Cited by 5 · see citing works

Association of serotonin reuptake inhibitors with asthma control

Gajewski, A. J., Palka, J. M., Raitt, J. M., Agarwal, C. D., Khan, D. A., kao, C. H.-Y., & Brown, E. S. (2023) · Allergy and Asthma Proceedings · doi:10.2500/aap.2023.44.230043 · Cited by 5 · see citing works

A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.

McKernan, K. J., Kane, L. T., Helbert, Y., Zhang, L., Houde, N., & McLaughlin, S. (2021) · F1000Research · doi:10.12688/f1000research.55301.2 · Cited by 4 · see citing works

SHP-1 alleviates acute liver injury caused by Escherichia coli sepsis through negatively regulating the canonical and non-canonical NFκB signaling pathways

Wang, N., Tan, S., Liu, H., Wang, M., Xia, J., Zhang, W., Wang, M., Liu, H., & Sha, Z. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113371 · Cited by 4 · see citing works

Fluoxetine and Molnupiravir: A Synergistic Combination for COVID-19 Treatment?

Pashaei, Y. (2022) · Hospital Pharmacy · doi:10.1177/00185787211073465 · Cited by 3 · see citing works

Prevalence of COVID-19 and Psychotropic Drug Treatment in Psychiatric In-patients in Germany in 2020: Results from a Nationwide Pilot Survey

Mueller, J. K., Ahrens, K. F., Bauer, M., Baune, B. T., Borgwardt, S., Deckert, J., Domschke, K., Ellwanger, R., Fallgatter, A. J., Frodl, T., et al. (2023) · Pharmacopsychiatry · doi:10.1055/a-2177-3056 · Cited by 4 · see citing works

In silico analysis of the antidepressant fluoxetine and similar drugs as inhibitors of the human protein acid sphingomyelinase: a related SARS-CoV-2 inhibition pathway

Pauletto, P. J. T., Bortoli, M., Omage, F. B., Delgado, C. P., Nogara, P. A., Orian, L., & da Rocha, J. B. T. (2022) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2022.2148124 · Cited by 3 · see citing works

ANTI-DEPRESSANTS AND COVID-19: A NEW RAY OF HOPE

Khan, E. I., Jani, I., Bardhan, M., & Hasan, M. M. (2022) · Psychiatria Danubina · doi:10.24869/psyd.2022.171 · Cited by 2 · see citing works

Pharmacotherapeutic approach toward urological medications and vaccination during COVID-19: a narrative review

Shafiekhani, M., Dehghani, A., Shahisavandi, M., Nabavizadeh, S. A., Kabiri, M., Hassani, A. H., & Haghpanah, A. (2021) · Therapeutic Advances in Urology · doi:10.1177/17562872211046794 · Cited by 2 · see citing works

SSRIs in the course of COVID‐19 pneumonia: Evidence of effectiveness of antidepressants on acute inflammation. A retrospective study

Fei, L., Bozza, B., Melani, G., Righi, L., Santarelli, G., Boy, O. B., Benedetti, D., Falone, A., Flaccomio, D., Giuranno, G., et al. (2023) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.2887 · Cited by 2 · see citing works

Fluoxetine Reshapes Macrophage Membrane Sphingolipids and Inflammatory Response Without Affecting Extracellular Vesicle Biogenesis upon Inactivated SARS-CoV-2 Stimulation

de Carvalho, J. C. S., Nobre-Azevedo, P., Silva-Neto, P. V. D., Oliveira, B. T. M., Tavares, L. A., Toro, D. M., Borges, A. O., Nascimento, M. A. V., Arruda, E., Júnior, R. B. M., et al. (2026) · Membranes · doi:10.3390/membranes16030098 · Cited by 1 · see citing works

Screening of the FDA-approved drug library identifies CCL17 inhibitors that block arthritic pain

Eivazitork, M., Lupancu, T. J., Lim, K. K. T., Huang, Y., Hamilton, J. A., Lee, M.-C., & Achuthan, A. A. (2025) · Scientific Reports · doi:10.1038/s41598-025-12191-4 · Cited by 1 · see citing works

A Hybrid AI-driven Algorithm to Uncover Potential Therapeutic Targets for COVID-19 Using Network-based Drug RepurposingPreprint

Marchi, C., & Martins, D. (2022) · Preprints.org · doi:10.20944/preprints202207.0004.v1

Post-Traumatic Stress Disorder after Cardiomyopathy as an Adverse Effect of BNT162b2 mRNA Vaccine in Young Male

Imren, K. U. R. T. (2022) · Journal of Clinical Case Studies Reviews & Reports · doi:10.47363/jccsr/2021(4)204

Fluvoxamine and fluoxetine in the treatment of patients with the novel coronavirus infection

Artamonov, N. M., Maksimov, M. L., & Zvegintseva, A. A. (2022) · Glavvrač (Chief Medical Officer) · doi:10.33920/med-03-2206-09

Post-Traumatic Stress Disorder after Cardiomyopathy as an Adverse Effect of BNT162b2 mRNA Vaccine in Young Male

Imren, K. U. R. T. (2022) · Journal of Clinical Case Studies Reviews & Reports · doi:10.47363/jccsr/2022(4)204

Efeito do pré-tratamento com fluoxetina sobre a hipotermia induzida por endotoxemia

Trajano, I. P. (2024) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2024.tde-10062024-092642

Exploring early add-on celecoxib treatment in OCD: Results from a preliminary randomized, double-blind, placebo-controlled trial

Singh, S., Nischal, A., Nischal, A., Singh, S. K., Singh, V., & Tripathi, A. (2025) · Journal of Psychopharmacology · doi:10.1177/02698811251389556

Eleutheroside B alleviates LPS-induced depressive-like behaviors by suppressing the TLR4/MyD88/NF-κB signaling pathway in the dentate gyrus

Wu, S., Jiang, Y., Zhai, C., Li, P., Yang, H., Xu, C., Wang, Y., Liu, J.-G., & Zhang, L. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116727

Study on the network pharmacology of scorpion in the treatment of viral pneumonia

Xiong, L. (2023) · Integrate Medicine · doi:10.61958/imdr2428

Computational toxicology analysis of candidate drivers and pathways in HRZE-associated drug-induced liver injury

Lai, Y., Yang, X., Tian, H., Zhou, Y., & Liu, F. (2026) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2026.2670504

Could Fluoxetine Confer a Favourable Immuno‐Inflammatory Profile in a Murine Model of Acute Toxoplasmosis?

ELGENDY, W. M. A., Othman, A. A., Khalifa, B. N., Soliman, N. A., Mohamed, D. A., & Younis, S. S. (2026) · Parasite Immunology · doi:10.1111/pim.70093

Repurposing Selective Serotonin Reuptake Inhibitors as Immunomodulators: Effects on Macrophage Activation and Polarization

Aldweik, M. H., Aydemir, E., & Ayaz, F. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06160-9

Psychotropic Drugs: A Promising Non‐Antibiotic Agent to Combat Multi‐Drug‐Resistant Microorganisms

Singh, I. P., Singh, H., Sharma, D., Keshri, A., Gaurav, N., Dhakad, M. S., & Beg, M. M. A. (2026) · Drug Development Research · doi:10.1002/ddr.70380

Fluoxetine as an Anti-Inflammatory Therapy in SARS-CoV-2 Infection - Protocol v1.1 v1Preprint

Creeden, J. F., Imami, A. S., Eby, H., Gillman, C. E., Becker, K. N., Reigle, J., Andari, E., Pan, Z. K., O'Donovan, S. M., McCullumsmith, R. E., et al. (2021) · doi:10.17504/protocols.io.bscjnaun

Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model

Péricat, D., Leon‐Icaza, S. A., Rico, M. S., Mühle, C., Zoicas, I., Schumacher, F., Planès, R., Mazars, R., Gros, G., Carpinteiro, A., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113623 · Cited by 26 · see citing works

Profiling Differential Effects of 5 Selective Serotonin Reuptake Inhibitors on TLRs-Dependent and -Independent IL-6 Production in Immune Cells Identifies Fluoxetine as Preferred Anti-Inflammatory Drug Candidate

Takenaka, Y., Tanaka, R., Kitabatake, K., Kuramochi, K., Aoki, S., & Tsukimoto, M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.874375 · Cited by 20 · see citing works

Inhibitory effect of selective serotonin reuptake inhibitors (SSRIs) on Toll like receptor-dependent and -independent production of IL-6

Takenaka, Y., Tanaka, R., Kitabatake, K., Kuramochi, K., Aoki, S., & Tsukimoto, M. (2022) · Proceedings for Annual Meeting of The Japanese Pharmacological Society · doi:10.1254/jpssuppl.96.0_2-b-ss11-4

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

Gasparello, J., D’Aversa, E., Papi, C., Gambari, L., Grigolo, B., Borgatti, M., Finotti, A., & Gambari, R. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153583 · Cited by 49 · see citing works