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Human Bed Nucleus of the Stria Terminalis Indexes Hypervigilant Threat Monitoring
Open accessAbstract
Background Though a key symptom underlying many anxiety disorders is hypervigilant threat monitoring, its biological bases in humans remain poorly understood. Animal models suggest that anxious processes such as hypervigilant threat monitoring are distinct from cued fear-like responses and mediated by the bed nucleus of the stria terminalis (BNST). Here, we applied psychophysiological and neuroimaging methodologies sensitive to sustained arousal-based responses to test the role of the human BNST in mediating environmental threat monitoring, a potential experimental model for sustained anxiety symptoms.Methods Healthy participants (n = 50) with varying trait anxiety performed an environmental threat-monitoring task during functional magnetic resonance imaging where a stimulus line continuously fluctuated in height, providing information relevant to subsequent risk for electric shocks. Skin conductance was collected in a separate cohort (n = 47) to validate task-evoked modulation of physiological arousal.Results A forebrain region consistent with the BNST showed greater overall recruitment and exaggerated tracking of threat proximity in individuals with greater anxiety. The insular cortex tracked threat proximity across all participants, showed exaggerated threat proximity responding with greater anxiety, and showed enhanced recruitment when threat proximity was ostensibly controllable.Conclusions Activity in the BNST and insula continuously monitored changes in environmental threat level and also subserved hypervigilant threat-monitoring processes in more highly trait anxious individuals. These findings bridge human and animal research informing the role of the BNST in anxious-related processes. In addition, these findings suggest that continuous functional magnetic resonance imaging paradigms offer promise in further elucidating the neural circuitries supporting sustained anticipatory features of anxiety.
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In the citing paper
“BNST activation also tracks sustained anxiety in humans [182]”
From Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory (2015) · cites this paper as [182]
In the citing paper
“Also, it appears to be involved in anticipatory anxiety and threat monitoring.[32][33][34]”
From Electrical stimulation in the bed nucleus of the stria terminalis alleviates severe obsessive-compulsive disorder (2016) · cites this paper as [33]
In the citing paper
“However, Somerville et al. (2010) recently examined the role of the BNST in anxious-related vigilance.”
From Phasic and sustained fear in humans elicits distinct patterns of brain activity (2011) · cites this paper as Somerville et al. (2010)
In the citing paper
“A comparable area of the BNST has been associated with hypervigilant threat monitoring (Somerville et al., 2010).”
From Phasic and sustained fear in humans elicits distinct patterns of brain activity (2011) · cites this paper as Somerville et al., 2010
In the citing paper
“BNST activity tracked with shock risk and was greatest during the high-risk periods.”
From The human BNST: functional role in anxiety and addiction (2016) · cites this paper as Somerville et al (2010)
In the citing paper
“In addition, although Somerville et al (2010) found increased amygdala ROI activity in a simple contrast of threat4safe, amygdala activity did not show a linear increase with increased risk of shock, was not significant in the wholebrain analysis, and did not show a relationship with trait anxiety-findings that were all observed for the BNST.”
From The human BNST: functional role in anxiety and addiction (2016) · cites this paper as Somerville et al (2010)
In the citing paper
“We have reviewed evidence that the BNST is engaged by anxiogenic tasks in healthy adults, with two studies showing individual differences in normative anxiety are associated with greater BNST activation (Somerville et al, 2010) and functional connectivity (McMenamin et al, 2014)”
From The human BNST: functional role in anxiety and addiction (2016) · cites this paper as Somerville et al, 2010
In the citing paper
“No amygdala ROI findings”
From The human BNST: functional role in anxiety and addiction (2016) · cites this paper as Somerville et al (2010)
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Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
(1970) · Cited by 24,983
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Applied Multivariate Statistics for the Social Sciences
Stevens, J. P. (2012) · Routledge eBooks · doi:10.4324/9780203843130 · Cited by 10,652
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
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Lezak, K. R., Roelke, E., Harris, O. M., Choi, I., Edwards, S. H. A., Gick, N., Cocchiaro, G. F., Missig, G., Roman, C. W., Braas, K. M., et al. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.03.007 · Cited by 51
Personality in cross-cultural perspective
Dragūns, J. G. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9780511596544.035 · Cited by 51
Neuromodulation for the treatment of eating disorders and obesity
Lee, D. J., Elias, G. J. B., & Lozano, A. M. (2017) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125317743435 · Cited by 50
Phasic and Sustained Fear are Pharmacologically Dissociable in Rats
Miles, L., Davis, M., & Walker, D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.29 · Cited by 47
Hammack, S. E., Todd, T. P., Kocho-Schellenberg, M., & Bouton, M. E. (2015) · Behavioral Neuroscience · doi:10.1037/bne0000088 · Cited by 50
Inhalation of 7.5% carbon dioxide increases alerting and orienting attention network function
Garner, M., Attwood, A., Baldwin, D., & Munafo, M. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2690-4 · Cited by 51
Brinkmann, L., Buff, C., Feldker, K., Neumeister, P., Heitmann, C. Y., Hofmann, D., Bruchmann, M., Herrmann, M. J., & Straube, T. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.10.054 · Cited by 49
Motzkin, J. C., Philippi, C. L., Oler, J. A., Kalin, N. H., Başkaya, M. K., & Koenigs, M. R. (2014) · Cortex · doi:10.1016/j.cortex.2014.11.013 · Cited by 50
deCampo, D. M., & Fudge, J. L. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23340 · Cited by 48
Extended amygdala connectivity changes during sustained shock anticipation
Torrisi, S., Gorka, A. X., González-Castillo, J., O’Connell, K., Balderston, N. L., Grillon, C., & Ernst, M. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0074-6 · Cited by 49
The antidepressant effect of light therapy from retinal projections.
Li, X., & Li, X. (2018) · Neuroscience Bulletin · doi:10.1007/s12264-018-0210-1 · Cited by 47
Haaker, J., Lonsdorf, T. B., & Kalisch, R. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.07.016 · Cited by 47
Context conditioning in humans using commercially available immersive Virtual Reality
Kroes, M. C. W., Dunsmoor, J. E., Mackey, W. E., McClay, M., & Phelps, E. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-08184-7 · Cited by 54
Naaz, F., Knight, L. K., & Depue, B. E. (2019) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01369 · Cited by 49
Reduced White Matter Integrity in Antisocial Personality Disorder: A Diffusion Tensor Imaging Study
Jiang, W., Shi, F., Liu, H., Li, G., Ding, Z., Shen, H., Shen, C., Lee, S., Hu, D., Wang, W., et al. (2017) · Scientific Reports · doi:10.1038/srep43002 · Cited by 46
Kasten, C. R., Carzoli, K. L., Sharfman, N. M., Henderson, T., Holmgren, E. B., Lerner, M. R., Miller, M. C., & Wills, T. A. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0670-7 · Cited by 43
Awasthi, S., Pan, H., LeDoux, J. E., Cloître, M., Altemus, M. M., McEwen, B. S., Silbersweig, D., & Stern, E. R. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102442 · Cited by 42
Trait Anxiety Modulates Brain Activity during Performance of Verbal Fluency Tasks
Gawda, B., & Szepietowska, E. M. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00010 · Cited by 46
Shackman, A. J., Fox, A. S., Oler, J. A., Shelton, S. E., Oakes, T. R., Davidson, R. J., & Kalin, N. H. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.132 · Cited by 40
Parsafar, P., & Davis, E. L. (2018) · Springer eBooks · doi:10.1007/978-3-319-77619-4_2 · Cited by 44
Zheng, H., Reiner, D. J., Hayes, M. R., & Rinaman, L. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2180-18.2019 · Cited by 42
Martinon, D., Lis, P., Roman, A. N., Tornesi, P., Applebey, S. V., Buechner, G., Olivera, V., & Dabrowska, J. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0474-x · Cited by 41
Personality Neuroscience and the Five Factor Model
Allen, T. A., & DeYoung, C. G. (2016) · Oxford Handbooks Online · doi:10.1093/oxfordhb/9780199352487.013.26 · Cited by 143
Gorka, S. M., Kreutzer, K. A., Petrey, K., Radoman, M., & Phan, K. L. (2019) · Addiction Biology · doi:10.1111/adb.12774 · Cited by 43
Anxiogenic effects of CGRP within the BNST may be mediated by CRF acting at BNST CRFR1 receptors
Sink, K. S., Chung, A., Ressler, K. J., Davis, M., & Walker, D. L. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.01.024 · Cited by 41
Luyten, L., Casteels, C., Vansteenwegen, D., van Kuyck, K., Koole, M., Van Laere, K., & Nuttin, B. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3701-11.2012 · Cited by 39
Transitional and translational studies of risk for anxiety
Casey, B. J., Ruberry, E. J., Libby, V., Glatt, C. E., Hare, T. A., Soliman, F., Duhoux, S., Frielingsdorf, H., & Tottenham, N. (2011) · Depression and Anxiety · doi:10.1002/da.20783 · Cited by 40
Pedersen, W. S., Muftuler, L. T., & Larson, C. L. (2017) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsx133 · Cited by 38
Badea, A., Kamnaksh, A., Anderson, R. J., Calabrese, E., Long, J. B., & Agoston, D. V. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.01.007 · Cited by 38
Knight, L. K., & Depue, B. E. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00510 · Cited by 43
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Ramsay, I., Yzer, M. C., Luciana, M., Vohs, K., & MacDonald, A. W. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00391 · Cited by 37
Contreras‐Rodríguez, O., Vilar‐López, R., Andrews, Z. B., Navas, J. F., Soriano‐Mas, C., & Verdejo‐García, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-09874-y · Cited by 36
Bruzsik, B., Bíró, L., Sarosdi, K. R., Zelena, D., Sipos, E., Szebik, H., Török, B., Mikics, É., & Tóth, M. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100415 · Cited by 34
Nikolaou, K., Field, M., Critchley, H., & Duka, T. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.34 · Cited by 32
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King, S. B., Lezak, K. R., O’Reilly, M. L., Toufexis, D. J., Falls, W. A., Braas, K. M., May, V., & Hammack, S. E. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.16 · Cited by 33
Ben‐Eliyahu, A., & Zeidner, M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.041 · Cited by 33
Sympathetic pain? A role of poor parasympathetic nervous system engagement in vicarious pain states
Nazarewicz, J., Verdejo‐García, A., & Giummarra, M. J. (2015) · Psychophysiology · doi:10.1111/psyp.12516 · Cited by 32
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Markota, M., Sin, J. M., Pantazopoulos, H., Jonilionis, R., & Berretta, S. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu084 · Cited by 31
Daniel, S., Guo, J., & Rainnie, D. G. (2017) · The Journal of Comparative Neurology · doi:10.1002/cne.24202 · Cited by 31
Kaye, J. T., Bradford, D. E., Magruder, K. P., & Curtin, J. J. (2017) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2017.78.353 · Cited by 29
Neural substrates of human fear generalization: A 7T-fMRI investigation
Huggins, A. A., Tomas, C. W., Parisi, E. A., Bennett, K. P., Miskovic, V., & Larson, C. L. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118308 · Cited by 31
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Casey, B. J., Pattwell, S. S., Glatt, C. E., & Lee, F. S. (2012) · Annual Review of Medicine · doi:10.1146/annurev-med-052611-130408 · Cited by 33
Threat and Reward Imminence Processing in the Human Brain
Murty, D. V. P. S., Song, S., Surampudi, S. G., & Pessoa, L. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1778-22.2023 · Cited by 33
DeYoung, C. G., & Blain, S. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.026 · Cited by 34
Long-term behavioral consequences of stress exposure in adolescent versus young adult rats
Saul, M. L., Tylee, D. S., Becoats, K., Guerrero, B. G., Sweeney, P. R., Helmreich, D. L., & Fudge, J. L. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.01.022 · Cited by 28
Air Hunger: A Primal Sensation and a Primary Element of Dyspnea
Banzett, R. B., Lansing, R., & Binks, A. P. (2021) · Comprehensive physiology · doi:10.1002/j.2040-4603.2021.tb00156.x · Cited by 27
Demertzis, K. H., & Craske, M. G. (2006) · Springer eBooks · doi:10.1007/978-0-387-28370-8_30 · Cited by 27
Rossi, V., & Pourtois, G. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.04.064 · Cited by 27
Smith, C. D., Piasecki, C. C., Weera, M. M., Olszewicz, J., & Lonstein, J. S. (2013) · Behavioral Neuroscience · doi:10.1037/a0032776 · Cited by 27
Goode, T. D., Kim, J., & Maren, S. (2015) · eNeuro · doi:10.1523/eneuro.0037-15.2015 · Cited by 28
Roles of the bed nucleus of the stria terminalis and amygdala in fear reactions
Hulsman, A. M., Terburg, D., Roelofs, K., & Klumpers, F. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00027-3 · Cited by 29
Yu, W., Caira, C. M., del R. Rivera Sanchez, N., Moseley, G. A., & Kash, T. L. (2021) · Scientific Reports · doi:10.1038/s41598-021-91672-8 · Cited by 25
Rehbein, M., Wessing, I., Zwitserlood, P., Steinberg, C., Eden, A., Dobel, C., & Junghöfer, M. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00155 · Cited by 25
Neural Mechanisms of Emotions and Affect
Aday, J. S., Rizer, W., & Carlson, J. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801851-4.00002-1 · Cited by 27
Altered Neural Processing of Threat in Alcohol-Dependent Men
Yang, H., Devous, M. D., Briggs, R. W., Spence, J. S., Xiao, H., Kreyling, N., & Adinoff, B. H. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12187 · Cited by 27
Greenberg, G. D., van Westerhuyzen, J. A., Bales, K. L., & Trainor, B. C. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.04.063 · Cited by 24
Dynamics of Intersubject Brain Networks during Anxious Anticipation
Najafi, M., Kinnison, J., & Pessoa, L. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00552 · Cited by 25
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Karim, H. T., Tudorascu, D., Aizenstein, H. J., Walker, S. E., Good, R., & Andreescu, C. (2016) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.07.015 · Cited by 29
Pedersen, W. S., Balderston, N. L., Miskovich, T. A., Belleau, E. L., Helmstetter, F. J., & Larson, C. L. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw178 · Cited by 26
Electrical stimulation of the bed nucleus of the stria terminalis reduces anxiety in a rat model
Luyck, K., Tambuyzer, T., Deprez, M., Rangarajan, J. R., Nuttin, B., & Luyten, L. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.2 · Cited by 24
Dzafic, I., Oestreich, L., Martin, A. K., Mowry, B. J., & Burianová, H. (2019) · Human Brain Mapping · doi:10.1002/hbm.24779 · Cited by 23
Makinson, R. A., Lundgren, K. H., Seroogy, K. B., & Herman, J. P. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.04.025 · Cited by 22
Pedersen, W. S., Muftuler, L. T., & Larson, C. L. (2019) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsz095 · Cited by 20
Maita, I., Bazer, A. S., Blackford, J. U., & Samuels, B. A. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00026-1 · Cited by 23
Reisenzein, R., Hildebrandt, A., & Weber, H. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.009 · Cited by 26
Depue, R. A., & Fu, Y. (2011) · International Review of Psychiatry · doi:10.3109/09540261.2011.599315 · Cited by 24
The role of the anteriolateral bed nucleus of the stria terminalis in stress-induced nociception
Tran, L., Wiskur, B. J., & Meerveld, B. G. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00501.2011 · Cited by 22
Duka, T., & Stephens, D. (2014) · Current Addiction Reports · doi:10.1007/s40429-013-0009-0 · Cited by 22
Jenks, S. K., Zhang, S., Li, C.-S. R., & Hu, S. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.12.017 · Cited by 22
Sink, K. S., Davis, M., & Walker, D. L. (2013) · Learning & Memory · doi:10.1101/lm.032482.113 · Cited by 23
Chen, X., Yue, J.-H., Luo, Y., Huang, L.-Y., Li, B.-X., & Wen, S.-L. (2021) · Behavioral and Brain Functions · doi:10.1186/s12993-021-00177-x · Cited by 19
FKBP51 in the Oval Bed Nucleus of the Stria Terminalis Regulates Anxiety-Like Behavior
Engelhardt, C., Tang, F., Elkhateib, R., Bordes, J., Brix, L., van Doeselaar, L., Häusl, A., Pöhlmann, M., Schraut, K.-G., Yang, H.-Q., et al. (2021) · eNeuro · doi:10.1523/eneuro.0425-21.2021 · Cited by 20
Threat vigilance and intrinsic amygdala connectivity
Kirk, P. A., Holmes, A. J., & Robinson, O. J. (2022) · Human Brain Mapping · doi:10.1002/hbm.25851 · Cited by 42
Pedersen, W. S., Muftuler, L. T., & Larson, C. L. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.05.009 · Cited by 20
Clauss, J. A. (2019) · General Psychiatry · doi:10.1136/gpsych-2019-100137 · Cited by 21
Activation in bed nucleus of the stria terminalis (BNST) corresponds to everyday helping
Vekaria, K. M., O’Connell, K., Rhoads, S. A., Brethel-Haurwitz, K. M., Cardinale, E. M., Robertson, E., Walitt, B. T., VanMeter, J. W., & Marsh, A. A. (2020) · Cortex · doi:10.1016/j.cortex.2020.02.001 · Cited by 22
The Effects of Prenatal Bisphenol a Exposure on Brain Volume of Children and Young MicePreprint
Zheng, J., Reynolds, J. E., Long, M., Ostertag, C., Pollock, T., Hamilton, M., Dunn, J. F., Liu, J., Martin, J. W., Grohs, M. N., et al. (2022) · SSRN Electronic Journal · doi:10.1016/j.envres.2022.114040 · Cited by 24
Castagna, P. J., Roye, S., Calamia, M. R., Owens-French, J., Davis, T. E., & Greening, S. G. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9772-1 · Cited by 21
Grogans, S. E., Hur, J., Barstead, M. G., Anderson, A. S., Islam, S., Kim, H. C., Kuhn, M., Tillman, R. M., Fox, A. S., Smith, J. F., et al. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1868-23.2024 · Cited by 22
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Taghva, A. S., Oluigbo, C. O., Corrigan, J. D., & Rezai, A. R. (2013) · Stereotactic and Functional Neurosurgery · doi:10.1159/000343148 · Cited by 20
Cano, M., Alonso, P., Martínez‐Zalacaín, I., Subirà, M., Real, E., Segalàs, C., Pujol, J., Cardoner, N., Menchón, J. M., & Soriano‐Mas, C. (2017) · Psychological Medicine · doi:10.1017/s0033291717002288 · Cited by 21
Hofmann, D., & Straube, T. (2019) · Human Brain Mapping · doi:10.1002/hbm.24555 · Cited by 19
Banihashemi, L., Peng, C. W., Rangarajan, A., Karim, H. T., Wallace, M. L., Sibbach, B. M., Singh, J., Stinley, M. M., Germain, A., & Aizenstein, H. J. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.805049 · Cited by 19
Striatal–limbic activation is associated with intensity of anticipatory anxiety
Yang, H., Spence, J. S., Devous, M. D., Briggs, R. W., Goyal, A., Xiao, H., Yadav, H. C., & Adinoff, B. H. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2012.10.001 · Cited by 20
Ressler, R. L., Goode, T. D., Evemy, C. G., & Maren, S. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107281 · Cited by 20
Bortolini, T., Laport, M. C., Latgé-Tovar, S., Fischer, R. D., Zahn, R., de Oliveira‐Souza, R., & Moll, J. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105584 · Cited by 22
Discovering networks altered by potential threat (“anxiety”) using quadratic discriminant analysis
McMenamin, B. W., & Pessoa, L. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.05.002 · Cited by 19
Geng, F., Zhang, J., Wu, J., Zou, W.-J., Liang, Z.-P., Bi, L., Liu, J., Kong, Y., Huang, C.-Q., Li, X., et al. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.05.018 · Cited by 19
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Metadata
- Authors
- Somerville, L. H., Whalen, P. J., & Kelley, W. M.
- Affiliations
- Dartmouth College (US)
- Corresponding author
- Somerville, Leah H.
- ORCID
- Somerville, Leah H.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 68
- Issue
- 5
- Pages
- 416-424
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC2921460
- OpenAlex
- W1972368693
- Cited by
- 351
- References
- 97
- Citations by year
- 2026: 5 · 2025: 18 · 2024: 14 · 2023: 16 · 2022: 10 · 2021: 21 · 2020: 54 · 2019: 27 · 2018: 15 · 2017: 31 · 2016: 25 · 2015: 26 · 2014: 22 · 2013: 20 · 2012: 29
- FWCI
- 27.46
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Science Foundation Graduate Research Fellowship (DA007274, NSF0746220, MH080716)
- Dartmouth Brain Imaging Center
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- bed nucleus of the stria terminalis, trait anxiety, environmental hazards, insula, anticipatory anxiety, skin conductance, anxiety disorders
- MeSH terms
- Animals, Anxiety, Anxiety Disorders, Arousal, Behavior, Animal, Fear, Humans, Magnetic Resonance Imaging, Psychological Techniques, Septal Nuclei, Reflex, Startle, Models, Animal
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