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Altered function and connectivity of the medial frontal cortex in pediatric obsessive compulsive disorder
Open accessAbstract
Background Exaggerated concern for correct performance has been linked to hyperactivity of the medial frontal cortex (MFC) in adult obsessive-compulsive disorder (OCD), but the role of the MFC during the early course of illness remains poorly understood. We tested whether hyperactive MFC-based performance monitoring function relates to altered MFC connectivity within task control and default mode networks in pediatric patients.Methods Eighteen pairs of OCD and matched healthy youth underwent functional magnetic resonance imaging during performance monitoring and at rest. Task-related hyperactivations in the posterior and ventral MFC were used as seeds for connectivity analyses during task and resting state.Results In posterior MFC, patients showed greater activation of dorsal anterior cingulate cortex (dACC) than control subjects, with greater activation predicting worse performance. In ventral MFC, control subjects exhibited deactivation, whereas patients activated this region. Compared with control subjects, patients showed increased dACC-ventral MFC connectivity during task and decreased dACC-right anterior operculum and ventral MFC-posterior cingulate connectivity during rest.Conclusions Excessive activation and increased interactions of posterior and ventral MFC during performance monitoring may combine with reduced resting state connectivity of these regions within networks for task control and default mode to reflect early markers of OCD. Alteration of reciprocal interactions between these networks could potentiate the intrusion of ventral MFC-based affectively laden, self-referential thoughts, while disrupting posterior MFC-based performance-monitoring function in young patients.
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“regions of the “default-mode” network (DMN) including VMPFC and posterior cingulate cortex deactivate with increases in externally-directed cognition (31-33) including that associated with error detection (34, 35).”
From Hyperactive error responses and altered connectivity in ventromedial and frontoinsular cortices in obsessive-compulsive disorder (2011) · cites this paper as [34]
In the citing paper
“In OCD, enlarged volume and hyperactive function of the ACC associate with deficits of cognitive control2,3,9, while vMFC alterations – especially hyperactivity in the orbitofrontal cortex – has been linked to excessive valuation of consequences from actions3.”
From Developmental alterations of frontal-striatal-thalamic connectivity in obsessive-compulsive disorder (2011) · cites this paper as [9]
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“Alteration of ACC recruitment by these functions has been repeatedly demonstrated in neuroimaging studies of OCD3, including in child patients9.”
From Developmental alterations of frontal-striatal-thalamic connectivity in obsessive-compulsive disorder (2011) · cites this paper as [9]
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“However, the development of ACC cognitive control function depends not only on the maturation of its connections within FSTC, but also on its role within other brain networks (e.g., cingulopercular network for task control13) implicated in both pediatric9 and adult28 OCD.”
From Developmental alterations of frontal-striatal-thalamic connectivity in obsessive-compulsive disorder (2011) · cites this paper as [9]
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Citations
Cites
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002) · NeuroImage · doi:10.1006/nimg.2002.1132 · Cited by 11,888
KAUFMAN, J., BIRMAHER, B., BRENT, D., RAO, U., FLYNN, C., MORECI, P., WILLIAMSON, D., & RYAN, N. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199707000-00021 · Cited by 10,148
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923
Psychophysiological and Modulatory Interactions in Neuroimaging
Friston, K. J., Buechel, C., Fink, G. R., Morris, J., Rolls, E., & Dolan, R. J. (1997) · NeuroImage · doi:10.1006/nimg.1997.0291 · Cited by 3,097
Gusnard, D. A., Akbudak, E., Shulman, G. L., & Raichle, M. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.071043098 · Cited by 2,997
The role of the medial frontal cortex in cognitive control
Ridderinkhof, K. R., Ullsperger, M., Crone, E. A., & Nieuwenhuis, S. (2004) · Science · doi:10.1126/science.1100301 · Cited by 2,974
Sridharan, D., Levitin, D. J., & Menon, V. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800005105 · Cited by 2,892
Anterior Cingulate Conflict Monitoring and Adjustments in Control
Kerns, J. G., Cohen, J. D., MacDonald, A. W., Cho, R. Y., Stenger, V. A., & Carter, C. S. (2004) · Science · doi:10.1126/science.1089910 · Cited by 2,891
Buckner, R. L., & Carroll, D. C. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.11.004 · Cited by 2,691
Distinct brain networks for adaptive and stable task control in humans
Dosenbach, N. U. F., Fair, D. A., Miezin, F. M., Cohen, A. L., Wenger, K. K., Dosenbach, R. A. T., Fox, M. D., Snyder, A. Z., Vincent, J. L., Raichle, M. E., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704320104 · Cited by 2,632
The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.
Kim, S.-W., Dysken, M., Pheley, A., & Hoover, K. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90039-6 · Cited by 2,333
The Multidimensional Anxiety Scale for Children (MASC): factor structure, reliability, and validity
MARCH, J. S., PARKER, J. D. A., SULLIVAN, K., STALLINGS, P., & CONNERS, C. K. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199704000-00019 · Cited by 2,236
Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214
Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D. E., & Gross, J. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.06.030 · Cited by 2,113
Self-Control in Decision-Making Involves Modulation of the vmPFC Valuation System
Hare, T. A., Camerer, C. F., & Rangel, A. (2009) · Science · doi:10.1126/science.1168450 · Cited by 1,928
Default-mode brain dysfunction in mental disorders: A systematic review
Broyd, S. J., Demanuele, C., Debener, S., Helps, S. K., James, C. J., & Sonuga-Barke, E. J. S. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.09.002 · Cited by 1,675
The neural bases of momentary lapses in attention
Weissman, D. H., Roberts, K. C., Visscher, K. M., & Woldorff, M. G. (2006) · Nature Neuroscience · doi:10.1038/nn1727 · Cited by 1,566
Etkin, A., Egner, T., Peraza, D. M., Kandel, E. R., & Hirsch, J. (2006) · Neuron · doi:10.1016/j.neuron.2006.07.029 · Cited by 1,360
The maturing architecture of the brain's default network
Fair, D. A., Cohen, A. L., Dosenbach, N. U. F., Church, J. A., Miezin, F. M., Barch, D. M., Raichle, M. E., Petersen, S. E., & Schlaggar, B. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800376105 · Cited by 1,314
Development of distinct control networks through segregation and integration
Fair, D. A., Dosenbach, N. U. F., Church, J. A., Cohen, A. L., Brahmbhatt, S., Miezin, F. M., Barch, D. M., Raichle, M. E., Petersen, S. E., & Schlaggar, B. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705843104 · Cited by 1,244
Multisubject fMRI Studies and Conjunction Analyses
Friston, K. J., Holmes, A. P., Price, C. J., Büchel, C., & Worsley, K. J. (1999) · NeuroImage · doi:10.1006/nimg.1999.0484 · Cited by 1,090
Mazoyer, B., Zago, L., Mellet, E., Bricogne, S., Etard, O., Houdé, O., Crivello, F., Joliot, M., Petit, L., & Tzourio-Mazoyer, N. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00437-8 · Cited by 906
Bush, G., Frazier, J. A., Rauch, S. L., Seidman, L. J., Whalen, P. J., Jenike, M. A., Rosen, B. R., & Biederman, J. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00083-9 · Cited by 866
Castellanos, F. X., Margulies, D. S., Kelly, C., Uddin, L. Q., Ghaffari, M., Kirsch, A., Shaw, D., Shehzad, Z., Di Martino, A., Biswal, B., et al. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.025 · Cited by 854
Development of large-scale functional brain networks in children
Supekar, K., Musen, M., & Menon, V. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000157 · Cited by 807
Action-Monitoring Dysfunction in Obsessive-Compulsive Disorder
Gehring, W. J., Himle, J., & Nisenson, L. G. (2000) · Psychological Science · doi:10.1111/1467-9280.00206 · Cited by 670
O'Doherty, J., Critchley, H., Deichmann, R., & Dolan, R. J. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-21-07931.2003 · Cited by 611
Failing to deactivate: Resting functional abnormalities in autism
Kennedy, D. P., Redcay, E., & Courchesne, E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600674103 · Cited by 543
The intrinsic functional organization of the brain is altered in autism
Kennedy, D. P., & Courchesne, E. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.10.052 · Cited by 515
The Neural Basis of the Psychomotor Vigilance Task
Drummond, S. P. A., Bischoff‐Grethe, A., Dinges, D. F., Ayalon, L., Mednick, S. C., & Meloy, M. J. (2005) · SLEEP · doi:10.1093/sleep/28.9.1059 · Cited by 504
Abnormal and normal obsessions—A replication
Salkovskis, P. M., & Harrison, J. (1984) · Behaviour Research and Therapy · doi:10.1016/0005-7967(84)90057-3 · Cited by 483
Empirical Analyses of BOLD fMRI Statistics
Aguirre, G. K., Zarahn, E., & D’Esposito, M. (1997) · NeuroImage · doi:10.1006/nimg.1997.0264 · Cited by 474
Functional disintegration in paranoid schizophrenia using resting-state fMRI
Zhou, Y., Liang, M., Tian, L., Wang, K., Hao, Y., Liu, H., Liu, Z., & Jiang, T. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.05.029 · Cited by 444
Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder
Fitzgerald, K. D., Welsh, R. C., Gehring, W. J., Abelson, J. L., Himle, J. A., Liberzon, I., & Taylor, S. F. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.038 · Cited by 378
Self-citationObsessive-Compulsive Disorder as a Disturbance of Security Motivation.
Szechtman, H., & Woody, E. Z. (2004) · Psychological Review · doi:10.1037/0033-295x.111.1.111 · Cited by 374
Neural Systems for Error Monitoring: Recent Findings and Theoretical Perspectives
Taylor, S. F., Stern, E. R., & Gehring, W. J. (2007) · The Neuroscientist · doi:10.1177/1073858406298184 · Cited by 368
Self-citationThakkar, K. N., Polli, F. E., Joseph, R. M., Tuch, D. S., Hadjikhani, N., Barton, J. J. S., & Manoach, D. S. (2008) · Brain · doi:10.1093/brain/awn099 · Cited by 367
Ursu, S., Stenger, V. A., Shear, M. K., Jones, M. R., & Carter, C. S. (2003) · Psychological Science · doi:10.1111/1467-9280.24411 · Cited by 341
Maltby, N., Tolin, D. F., Worhunsky, P., O'Keefe, T. M., & Kiehl, K. A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.041 · Cited by 331
GELLER, D. A., BIEDERMAN, J., FARAONE, S., AGRANAT, A., CRADOCK, K., HAGERMOSER, L., KIM, G., FRAZIER, J., & COFFEY, B. J. (2001) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200107000-00009 · Cited by 325
Multiple neuronal networks mediate sustained attention
Lawrence, N. S., Ross, T. J., Hoffmann, R., Garavan, H., & Stein, E. A. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903770007416 · Cited by 310
Bush, G., & Shin, L. M. (2006) · Nature Protocols · doi:10.1038/nprot.2006.48 · Cited by 309 · cited 6×
“Task Participants performed the MSIT (16) which requires identification of the ordinal value of the unique number among three digits, “1”, “2”, or “3” (e.g., for “311,” the target is “3”) by pressing a key with one of three fingers (“1” for index finger, “2” for middle finger, “3”for ring finger).”
MethodInfluentialSmith, A. B., Taylor, E., Brammer, M., Toone, B., & Rubia, K. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.6.1044 · Cited by 300
The Multi-Source Interference Task: validation study with fMRI in individual subjects
Bush, G., Shin, L. M., Holmes, J., Rosen, B. R., & Vogt, B. A. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001217 · Cited by 298
Wagner, G., Sinsel, E., Sobanski, T., Köhler, S., Marinou, V., Mentzel, H.-J., Sauer, H., & Schlösser, R. G. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.025 · Cited by 278
Functional and Biochemical Alterations of the Medial Frontal Cortex in Obsessive-Compulsive Disorder
Yücel, M., Harrison, B. J., Wood, S. J., Fornito, A., Wellard, R. M., Pujol, J., Clarke, K., Phillips, M. L., Kyrios, M., Velakoulis, D., et al. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.8.946 · Cited by 263
Characterizing the Response of PET and fMRI Data Using Multivariate Linear Models
Worsley, K. J., Poline, J., Friston, K. J., & Evans, A. C. (1997) · NeuroImage · doi:10.1006/nimg.1997.0294 · Cited by 258
Hajcak, G., Franklin, M. E., Foa, E. B., & Simons, R. F. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07010143 · Cited by 253
A cybernetic model of obsessive-compulsive psychopathology
Pitman, R. K. (1987) · Comprehensive Psychiatry · doi:10.1016/0010-440x(87)90070-8 · Cited by 229
Roberts, K. L., & Hall, D. A. (2008) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2008.20074 · Cited by 218
Polli, F. E., Barton, J. J. S., Cain, M. S., Thakkar, K. N., Rauch, S. L., & Manoach, D. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503657102 · Cited by 207
Bush, G., Spencer, T. J., Holmes, J., Shin, L. M., Valera, E. M., Seidman, L. J., Makris, N., Surman, C., Aleardi, M., Mick, E., et al. (2008) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2007.16 · Cited by 201
Rubia, K., Cubillo, A., Smith, A. B., Woolley, J., Heyman, I., & Brammer, M. J. (2010) · Human Brain Mapping · doi:10.1002/hbm.20864 · Cited by 192
Effects of antipsychotic and antidepressant drugs on action monitoring in healthy volunteers
de Bruijn, E. R. A., Sabbe, B. G. C., Hulstijn, W., Ruigt, G. S. F., & Verkes, R. J. (2006) · Brain Research · doi:10.1016/j.brainres.2006.01.006 · Cited by 164
Medial frontal cortex activity and loss-related responses to errors
Taylor, S. F., Martis, B., Fitzgerald, K. D., Welsh, R. C., Abelson, J. L., Liberzon, I., Himle, J. A., & Gehring, W. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4709-05.2006 · Cited by 160
Self-citationRubia, K., Halari, R., Cubillo, A., Mohammad, A., Scott, S., & Brammer, M. (2010) · Human Brain Mapping · doi:10.1002/hbm.20975 · Cited by 153
Functional MRI in attention-deficit hyperactivity disorder: Evidence for hypofrontality
Zang, Y., Jin, Z. H., Weng, X., Zhang, L., Zeng, Y., Yang, L., Wang, Y., Seidman, L. J., & Faraone, S. V. (2005) · Brain and Development · doi:10.1016/j.braindev.2004.11.009 · Cited by 149
Baxter, L. R., Saxena, S., Brody, A., Ackermann, R., Colgan, M., Schwartz, Allen-Martinez, Z., Fuster, J. M., & Me, P. (1996) · PubMed · doi:10.1053/scnp00100032 · Cited by 134
Obsessive-Compulsive Characteristics: From Symptoms to Syndrome
Apter, A. S., Fallon, T., King, R. A., RATZONI, G., Zohar, A. H., BINDER, M., Weizman, A., Leckman, J. F., Pauls, D. L., Kron, S., et al. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199607000-00016 · Cited by 112
Schwartz, J. M. (1999) · PhilPapers (PhilPapers Foundation) · Cited by 73
The development of performance-monitoring function in the posterior medial frontal cortex
Fitzgerald, K. D., Perkins, S. C., Angstadt, M., Johnson, T. D., Stern, E. R., Welsh, R. C., & Taylor, S. F. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.004 · Cited by 69
Self-citationMultishot 3D slice‐select tailored RF pulses for MRI
Stenger, V. A., Boada, F. E., & Noll, D. C. (2002) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10194 · Cited by 60
Kang, E., Lee, D. S., Kang, H., Lee, J. S., Oh, S. H., Lee, M. C., & Kim, C. S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.04.010 · Cited by 46
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Metadata
- Authors
- Fitzgerald, K. D., Stern, E. R., Angstadt, M., Nicholson-Muth, K. C., Maynor, M. R., Welsh, R. C., Hanna, G. L., & Taylor, S. F.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Fitzgerald, Kate Dimond
- ORCID
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2010-12
- Volume
- 68
- Issue
- 11
- Pages
- 1039-1047
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC2988474
- OpenAlex
- W2069603286
- Cited by
- 152
- References
- 68
- Citations by year
- 2026: 7 · 2025: 2 · 2024: 7 · 2023: 7 · 2022: 6 · 2021: 9 · 2020: 5 · 2019: 8 · 2018: 8 · 2017: 21 · 2016: 9 · 2015: 18 · 2014: 12 · 2013: 16 · 2012: 11
- FWCI
- 11.57
- Type
- journal article
- Language
- en
- Update notices
- erratum (2012-03-15)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Dana Foundation
- National Alliance for Research on Schizophrenia and Depression
- Todd Ouida Clinical Scholars Award
- National Institute of Mental Health (K23-MH082176, R01-MH071821)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- pediatric obsessive-compulsive disorder, medial frontal cortex, performance monitoring, dorsal anterior cingulate cortex, ventromedial prefrontal cortex, default mode network, resting-state functional connectivity, posterior cingulate cortex, self-referential processing
- MeSH terms
- Adolescent, Brain Mapping, Child, Female, Frontal Lobe, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Nerve Net, Neural Pathways, Obsessive-Compulsive Disorder, Psychiatric Status Rating Scales, Psychomotor Performance, Reaction Time, Cluster Analysis
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