Toll-Like Receptor 4 Regulates Chronic Stress-Induced Visceral Pain in Mice

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Low back pain and disc degeneration are decreased following chronic toll-like receptor 4 inhibition in a mouse model

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Mechanisms of Stress‐Induced Visceral Pain: Implications in Irritable Bowel Syndrome

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Blockade of TLR4 Within the Paraventricular Nucleus Attenuates Blood Pressure by Regulating ROS and Inflammatory Cytokines in Prehypertensive Rats

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A Fatal Alliance between Microglia, Inflammasomes, and Central Pain

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The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress

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Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress

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Toll-like receptor 4 methylation grade is linked to depressive symptom severity

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Microglial type I interferon signaling mediates chronic stress-induced synapse loss and social behavior deficits

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Spinal alarmin HMGB1 and the activation of TLR4 lead to chronic stress-induced nociceptive hypersensitivity in rodents

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The Roles of Periaqueductal Gray and Dorsal Raphe Nucleus Dopaminergic Systems in the Mechanisms of Thermal Hypersensitivity and Depression in Mice

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Nociplastic pain mechanisms and toll-like receptors as promising targets for its management

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Involvement of toll-like receptor 5 on mouse model of colonic hypersensitivity induced by neonatal maternal separation

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Toll-like receptor 5 knock-out mice exhibit a specific low level of anxiety

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Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord

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Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain’s pain circuitry

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Infusions of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produce antidepressant-like effects on learned helplessness rats through BDNF-TrkB signaling and AMPA receptor activation, and strengthen learning ability

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Toll-Like Receptor 4 in the Rat Caudal Medulla Mediates Tooth Pulp Inflammatory Pain

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Evaluation of the Impact of Some Single-Nucleotide Gene Polymorphisms on the Development of Adenomatous Polyps of the Colon in Patients with Irritable Bowel Syndrome

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Effects of Single and Long-Term Treatment with Caffeine on the Chronic Unpredictable Stress-Induced Changes in Nociception in Rodents

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Avaliação das consequências comportamentais da administração de um inibidor da via do TLR4 no córtex pré-frontal medial após exposição ao estresse e possível envolvimento do sistema endocanabinoide

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Additional file 2 of Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

Xu, M., Zhai, W., Zhang, Y., Pan, J., Li, J., & Huang, S. (2024) · Figshare · doi:10.6084/m9.figshare.26589171

Additional file 3 of Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

Xu, M., Zhai, W., Zhang, Y., Pan, J., Li, J., & Huang, S. (2024) · Figshare · doi:10.6084/m9.figshare.26589174

Additional file 1 of Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

Xu, M., Zhai, W., Zhang, Y., Pan, J., Li, J., & Huang, S. (2024) · Figshare · doi:10.6084/m9.figshare.26589168

Rescuing anxiety by targeting the neuronal-astrocytic iron signaling axis in male mice

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Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity

Tramullas, M., Finger, B. C., Dinan, T. G., & Cryan, J. F. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155367 · Cited by 61 · see citing works

Obesity Takes Its Toll on Visceral Pain:\n\t\t\t\t High-Fat Diet Induces Toll-Like Receptor 4- Dependent Visceral Hypersensitivity

Tramullas Fernández, M., Finger, B. C., Dinan, T. G., & Cryan, J. F. (2016) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation

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Activation of corticotropin-releasing factor neurons and microglia in paraventricular nucleus precipitates visceral hypersensitivity induced by colorectal distension in rats

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TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity

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