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Diminished medial prefrontal cortex activity in blood-injection-injury phobia
Abstract
We examined the effects of symptom induction on neural activation in blood-injection-injury (BII) phobia. Nine phobic and 10 non-phobic subjects participated in an fMRI study in which they were presented with disorder-relevant, generally disgust-inducing, generally fear-evoking and neutral pictures. We observed diminished medial prefrontal cortex (MPFC) activity in patients compared to controls for phobia-relevant and disgust-inducing pictures. The MPFC has been shown to be critically involved in the automatic and effortful cognitive regulation of emotions. Therefore, the results might reflect reduced cognitive control of emotions in BII phobics during the experience of phobic symptoms as well as during states of disgust. The latter response component might be a result of the elevated disgust sensitivity of BII phobics.
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BII-phobia patients show a reduction in inhibitory control by the medial prefrontal cortex compared to controls exposed to blood and wound pictures.
“Findings of Hermann et al. (2007) that suggest a reduction in inhibitory control by the medial prefrontal cortex in BII-phobia patients compared to controls exposed to blood and wound pictures may be additionally instructive in this context.”
From The psychophysiology of blood-injection-injury phobia: Looking beyond the diphasic response paradigm (2010) · cites this paper as Hermann et al. (2007)
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Cites
Measuring emotion: The self-assessment manikin and the semantic differential
Bradley, M. M., & Lang, P. J. (1994) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(94)90063-9 · Cited by 9,538
The cognitive control of emotion
OCHSNER, K., & GROSS, J. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.03.010 · Cited by 4,495
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977
Emotion and Cognition: Insights from Studies of the Human Amygdala
Phelps, E. A. (2006) · Annual Review of Psychology · doi:10.1146/annurev.psych.56.091103.070234 · Cited by 1,798
Shin, L. M., Wright, C. I., Cannistraro, P. A., Wedig, M. M., McMullin, K., Martis, B., Macklin, M. L., Lasko, N. B., Cavanagh, S. R., Krangel, T. S., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.273 · Cited by 960
Functional neuroimaging studies of human emotions
Phan, K. L., Wager, T. D., Taylor, S. F., & Liberzon, I. (2004) · CNS Spectrums · doi:10.1017/s1092852900009196 · Cited by 433
Flagged first, then by citations
Research works printed but not linked: 18
- Behrmann, 2004, Parietal cortex and attention, Current Opinion in Neurobiology, 14, 212, 10.1016/j.conb.2004.03.012 · DOI · Paper page
- deJong, 1998, Blood-injection-injury phobia and fear of spiders: domain specific individual differences in disgust sensitivity, Personality and Individual Differences, 24, 153, 10.1016/S0191-8869(97)00178-5 · DOI · Paper page
- Fredrikson, 1995, Functional neuroanatomy of visually elicited simple phobic fear: additional data and theoretical analysis, Psychophysiology, 32, 43, 10.1111/j.1469-8986.1995.tb03404.x · DOI
- Johanson, 1998, Brain function in spider phobia, Psychiatry Research Neuroimaging, 84, 101, 10.1016/S0925-4927(98)00051-1 · DOI
- Keedwell, 2005, A double dissociation of ventromedial prefrontal cortical responses to sad and happy stimuli in depressed and healthy individuals, Biological Psychiatry, 58, 495, 10.1016/j.biopsych.2005.04.035 · DOI · Paper page
- Kim, 2005, The psychobiology of anxiety, Clinical Neuroscience Research, 4, 335, 10.1016/j.cnr.2005.03.008 · DOI
- Klorman, 1974, Psychometric description of some fear-specific questionnaires, Behaviour Research, 5, 401
- Lorberbaum, 2004, Neural correlates of speech anticipatory anxiety in generalized social phobia, NeuroReport, 15, 2701
- Page, 1994, Blood-injury phobia, Clinical Psychology Review, 14, 443, 10.1016/0272-7358(94)90036-1 · DOI
- Page, 1997, The Blood-Injection Symptom Scale (BISS): assessing a structure of phobic symptoms elicited by blood and injections, Behaviour Research and Therapy, 5, 457, 10.1016/S0005-7967(96)00120-9 · DOI
- Schienle, 2002, The insula is not specifically involved in disgust processing: an fMRI study, NeuroReport, 13, 2023, 10.1097/00001756-200211150-00006 · DOI
- Schienle, 2002, A questionnaire for the assessment of disgust sensitivity, Zeitschrift für Klinische Psychologie und Psychotherapie, 31, 110, 10.1026/0084-5345.31.2.110 · DOI
- Schienle, 2003, Disgust processing in phobia of blood-injection injury, Journal of Psychophysiology, 17, 87, 10.1027//0269-8803.17.2.87 · DOI
- Schienle, 2005, Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures, Neuroscience Letters, 388, 1, 10.1016/j.neulet.2005.06.025 · DOI
- Schienle, 2006, FMRI responses to pictures of mutilation and contamination, Neuroscience Letters, 393, 174, 10.1016/j.neulet.2005.09.072 · DOI
- Tolin, 1997, Disgust and disgust sensitivity in blood-injection-injury and spider phobia, Behaviour Research and Therapy, 35, 949, 10.1016/S0005-7967(97)00048-X · DOI · Paper page
- Tzourio-Mazoyer, 2002, Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain, Neurolmage, 15, 273, 10.1006/nimg.2001.0978 · DOI · Paper page
- Wright, 2004, Disgust and the insula: fMRI responses to pictures of mutilation and contamination, NeuroReport, 15, 2347, 10.1097/00001756-200410250-00009 · DOI
Cited by
Sorted by citations
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.83 · Cited by 2,083
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Milad, M. R., & Rauch, S. L. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.003 · Cited by 847
Hahn, A., Stein, P., Windischberger, C., Weissenbacher, A., Spindelegger, C., Moser, E., Kasper, S., & Lanzenberger, R. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.064 · Cited by 385
Disgust, fear, and the anxiety disorders: a critical review
Cisler, J. M., Olatunji, B. O., & Lohr, J. M. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2008.09.007 · Cited by 307
Neural systems underlying approach and avoidance in anxiety disorders
Robin L., A., & Martin, P. P. (2010) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2010.12.4/raupperle · Cited by 227
Neurobiology of fear and specific phobias
Garcia, R. (2017) · Learning & Memory · doi:10.1101/lm.044115.116 · Cited by 239
Meta-analysis of functional brain imaging in specific phobia
Ipser, J. C., Singh, L., & Stein, D. J. (2013) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12055 · Cited by 142
Lueken, U., Kruschwitz, J. D., Muehlhan, M., Siegert, J., Hoyer, J., & Wittchen, H.-U. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.015 · Cited by 99
Functional neuroimaging in specific phobia
Del Casale, A., Ferracuti, S., Rapinesi, C., Serata, D., Piccirilli, M., Savoja, V., Kotzalidis, G. D., Manfredi, G., Angeletti, G., Tatarelli, R., et al. (2012) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2011.10.009 · Cited by 90
The psychophysiology of blood-injection-injury phobia: Looking beyond the diphasic response paradigm
Ritz, T., Meuret, A. E., & Ayala, E. S. (2010) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2010.05.007 · Cited by 74
“Findings of Hermann et al. (2007) that suggest a reduction in inhibitory control by the medial prefrontal cortex in BII-phobia patients compared to controls exposed to blood and wound pictures may be additionally instructive in this context.”
BackgroundCaseras, X., Giampietro, V., Lamas, A., Brammer, M., Vilarroya, O., Carmona, S., Rovira, M., Torrubia, R., & Mataix-Cols, D. (2010) · Psychological Medicine · doi:10.1017/s0033291709005972 · Cited by 69
Neurostructural Correlates of Two Subtypes of Specific Phobia: A Voxel-Based Morphometry Study
Hilbert, K., Evens, R., Isabel Maslowski, N., Wittchen, H.-U., & Lueken, U. (2015) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2014.12.003 · Cited by 40
Ritz, T., Meuret, A. E., & Simon, E. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2013.03.011 · Cited by 15
Metadata
- Authors
- Hermann, A., Schäfer, A., Walter, B., Stark, R., Vaitl, D., & Schienle, A.
- Affiliations
- Justus-Liebig-Universität Gießen (DE)
- University of Graz (AT)
- Corresponding author
- Hermann, Andrea
- Venue
- Biological Psychology
- Publisher
- Elsevier BV
- Published
- 2007-05
- Volume
- 75
- Issue
- 2
- Pages
- 124-130
- ISSN
- 0301-0511 (ISSN-L)
- OpenAlex
- W2047143432
- Cited by
- 91
- References
- 7
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 7 · 2017: 5 · 2016: 3 · 2015: 2 · 2014: 7 · 2013: 12 · 2012: 5
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- blood-injection-injury phobia, medial prefrontal cortex, symptom induction, disgust, cognitive emotion regulation, emotion regulation, fear, neuronal activation, phobia
- MeSH terms
- Adolescent, Adult, Amygdala, Arousal, Blood, Brain Mapping, Cerebral Cortex, Dominance, Cerebral, Emotions, Fear, Female, Gyrus Cinguli, Hippocampus, Humans, Image Processing, Computer-Assisted, Injections, Magnetic Resonance Imaging, Pattern Recognition, Visual, Personality Inventory, Phobic Disorders, Thalamus, Echo-Planar Imaging, Prefrontal Cortex, Syncope, Vasovagal
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