Cited by 91Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeural and Behavioral Psychology StudiesPsychosomatic Disorders and Their Treatments

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Diminished medial prefrontal cortex activity in blood-injection-injury phobia

Abstract

We examined the effects of symptom induction on neural activation in blood-injection-injury (BII) phobia. Nine phobic and 10 non-phobic subjects participated in an fMRI study in which they were presented with disorder-relevant, generally disgust-inducing, generally fear-evoking and neutral pictures. We observed diminished medial prefrontal cortex (MPFC) activity in patients compared to controls for phobia-relevant and disgust-inducing pictures. The MPFC has been shown to be critically involved in the automatic and effortful cognitive regulation of emotions. Therefore, the results might reflect reduced cognitive control of emotions in BII phobics during the experience of phobic symptoms as well as during states of disgust. The latter response component might be a result of the elevated disgust sensitivity of BII phobics.

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Crossref · 10.1016/j.biopsycho.2007.01.002

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  • BII-phobia patients show a reduction in inhibitory control by the medial prefrontal cortex compared to controls exposed to blood and wound pictures.

    “Findings of Hermann et al. (2007) that suggest a reduction in inhibitory control by the medial prefrontal cortex in BII-phobia patients compared to controls exposed to blood and wound pictures may be additionally instructive in this context.”

Citations

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Research works printed but not linked: 18

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Metadata

Authors
Hermann, A., Schäfer, A., Walter, B., Stark, R., Vaitl, D., & Schienle, A.
Affiliations
  • Justus-Liebig-Universität Gießen (DE)
  • University of Graz (AT)
Corresponding author
Hermann, Andrea
Venue
Biological Psychology
Publisher
Elsevier BV
Published
2007-05
Volume
75
Issue
2
Pages
124-130
ISSN
0301-0511 (ISSN-L)
OpenAlex
W2047143432
Cited by
91
References
7
Citations by year
2025: 1 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 7 · 2017: 5 · 2016: 3 · 2015: 2 · 2014: 7 · 2013: 12 · 2012: 5
FWCI
6.14
Type
journal article
Language
en
Open access
closed
Locations
  • Biological Psychology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
blood-injection-injury phobia, medial prefrontal cortex, symptom induction, disgust, cognitive emotion regulation, emotion regulation, fear, neuronal activation, phobia
MeSH terms
Adolescent, Adult, Amygdala, Arousal, Blood, Brain Mapping, Cerebral Cortex, Dominance, Cerebral, Emotions, Fear, Female, Gyrus Cinguli, Hippocampus, Humans, Image Processing, Computer-Assisted, Injections, Magnetic Resonance Imaging, Pattern Recognition, Visual, Personality Inventory, Phobic Disorders, Thalamus, Echo-Planar Imaging, Prefrontal Cortex, Syncope, Vasovagal

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