Cited by 109Personality Traits and PsychologyLipoproteins and Cardiovascular HealthCardiac Health and Mental Health

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Cholesterol, triglycerides, and the Five-Factor Model of personality

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Sutin, Angelina R., Terracciano, Antonio, Deiana, Barbara, Uda, Manuela, Schlessinger, David, Lakatta, Edward G., Costa Jr., Paul T.·2010·Biological Psychology

DOI 10.1016/j.biopsycho.2010.01.012PMC PMC2933037

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Abstract

Unhealthy lipid levels are among the leading controllable risk factors for coronary heart disease. To identify the psychological factors associated with dyslipidemia, this study investigates the personality correlates of cholesterol (total, LDL, and HDL) and triglycerides. A community-based sample (N=5532) from Sardinia, Italy, had their cholesterol and triglyceride levels assessed and completed a comprehensive personality questionnaire, the NEO-PI-R. All analyses controlled for age, sex, BMI, smoking, drinking, hypertension, and diabetes. Low Conscientiousness and traits related to impulsivity were associated with lower HDL cholesterol and higher triglycerides. Compared to the lowest 10%, those who scored in top 10% on Impulsivity had a 2.5 times greater risk of exceeding the clinical threshold for elevated triglycerides (OR=2.51, CI=1.56-4.07). In addition, sex moderated the association between trait depression (a component of Neuroticism) and HDL cholesterol, such that trait depression was associated with lower levels of HDL cholesterol in women but not men. When considering the connection between personality and health, unhealthy lipid profiles may be one intermediate biomarker between personality and morbidity and mortality.

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Authors: Sutin, A. R., Terracciano, A., Deiana, B., Uda, M., Schlessinger, D., Lakatta, E. G., & Costa Jr., P. T.
Affiliations: National Institutes of Health (US)
Institute of Genetic and Biomedical Research (IT)
Corresponding author: Sutin, Angelina R.
ORCID: Sutin, Angelina R.
Terracciano, Antonio
Uda, Manuela
Schlessinger, David
Lakatta, Edward G.
Venue: Biological Psychology
Publisher: Elsevier BV
Published: 2010-05
Volume: 84
Issue: 2
Pages: 186-191
ISSN: 0301-0511 (ISSN-L)
DOI: 10.1016/j.biopsycho.2010.01.012
PMC: PMC2933037
OpenAlex: W2070292687
Cited by: 109
References: 61
Citations by year: 2026: 1 · 2025: 4 · 2024: 7 · 2023: 5 · 2022: 6 · 2021: 4 · 2020: 7 · 2019: 7 · 2018: 8 · 2017: 7 · 2016: 4 · 2015: 7 · 2014: 9 · 2013: 8 · 2012: 10
FWCI: 11.63
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biological Psychology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (Z99 AG999999)
National Institute on Aging (ZIAAG000180, ZIAAG000197, ZIAAG000183)
Topics: Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords: dyslipidemia, cholesterol, triglycerides, Big Five personality traits, personality traits, impulsivity, conscientiousness, trait depression, neuroticism, HDL cholesterol, LDL cholesterol, coronary heart disease risk, sex differences, Sardinia
MeSH terms: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Blood Chemical Analysis, Cholesterol, Female, Humans, Italy, Male, Middle Aged, Personality, Personality Inventory, Residence Characteristics, Sex Factors, Triglycerides, Logistic Models, Young Adult

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Cholesterol, triglycerides, and the Five-Factor Model of personality

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