Lakatta, Edward G.

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 4,290

Biological, clinical and population relevance of 95 loci for blood lipids

Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., et al. (2010) · Nature

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 3,487

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Lakatta, E. G., & Levy, D. (2003) · Circulation

Cardiovascular Health and Disease PreventionCardiovascular Function and Risk Factors

Cited by 2,244

Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction

Ben-Shlomo, Y., Spears, M., Boustred, C., May, M., Anderson, S. G., Benjamin, E. J., Boutouyrie, P., Cameron, J., Chen, C.-H., Cruickshank, J. K., et al. (2014) · Journal of the American College of Cardiology

Cardiovascular Health and Disease PreventionCardiovascular Function and Risk Factors

Cited by 1,835

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

Scuteri, A., Sanna, S., Chen, W.-M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrú, M., Usala, G., et al. (2007) · PLoS Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 1,724

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

Willer, C. J., Sanna, S., Jackson, A. U., Scuteri, A., Bonnycastle, L. L., Clarke, R., Heath, S. C., Timpson, N. J., Najjar, S. S., Stringham, H. M., et al. (2008) · Nature Genetics

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 1,585

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Program, T. M. V., Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,381

Common variants at 30 loci contribute to polygenic dyslipidemia

Kathiresan, S., Willer, C. J., Peloso, G. M., Demissie, S., Musunuru, K., Schadt, E. E., Kaplan, L., Bennett, D., Li, Y., Tanaka, T., et al. (2009) · Nature Genetics

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 1,364

Genome-wide association study identifies eight loci associated with blood pressure

Wellcome Trust Case Control Consortium, Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Zhao, J. H., Heath, S. C., et al. (2009) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,215

Accelerated longitudinal decline of aerobic capacity in healthy older adults

Fleg, J. L., Morrell, C. H., Bos, A. G., Brant, L. J., Talbot, L. A., Wright, J. G., & Lakatta, E. G. (2005) · Circulation

Cardiovascular and exercise physiologyPhysical Activity and Health

Cited by 970

Superoxide flashes in single mitochondria

Wang, W., Fang, H., Groom, L., Cheng, A., Zhang, W., Liu, J., Wang, X., Li, K., Han, P., Zheng, M., et al. (2008) · Cell

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 715

Arterial Aging: Is It an Immutable Cardiovascular Risk Factor?

Najjar, S. S., Scuteri, A., & Lakatta, E. G. (2005) · Hypertension

Cardiovascular Health and Disease PreventionElasticity and Material Modeling

Cited by 640

Impact of age on the cardiovascular response to dynamic upright exercise in healthy men and women

Fleg, J. L., O'Connor, F., Gerstenblith, G., Becker, L. C., Clulow, J., Schulman, S. P., & Lakatta, E. G. (1995) · Journal of Applied Physiology

Cardiovascular and exercise physiologyCardiovascular Function and Risk Factors

Cited by 506

Age-associated Cardiovascular Changes in Health: Impact on Cardiovascular Disease in Older Persons

Lakatta, E. G. (2002) · Heart Failure Reviews

Cardiovascular Function and Risk FactorsCardiovascular Health and Disease Prevention

Cited by 445

Inflammation and endothelial dysfunction during aging: role of NF-κB

Csiszar, A., Wang, M., Lakatta, E. G., & Ungvari, Z. (2008) · Journal of Applied Physiology

Nitric Oxide and Endothelin EffectsNF-κB Signaling Pathways

Cited by 441

AGEMAP: A Gene Expression Database for Aging in Mice

Zahn, J. M., Poosala, S., Owen, A. B., Ingram, D. K., Lustig, A., Carter, A., Weeraratna, A. T., Taub, D. D., Gorospe, M., Mazan-Mamczarz, K., et al. (2007) · PLoS Genetics

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 431

Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes

Josephson, R. A., Silverman, H. S., Lakatta, E. G., Stern, M. D., & Zweier, J. L. (1991) · Journal of Biological Chemistry

Cardiac Ischemia and ReperfusionCardiac electrophysiology and arrhythmias

Cited by 272

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyCardiovascular Health and Disease Prevention

Cited by 212

Matrix metalloproteinases promote arterial remodeling in aging, hypertension, and atherosclerosis

Wang, M., Kim, S. H., Monticone, R. E., & Lakatta, E. G. (2015) · Hypertension

Protease and Inhibitor MechanismsRenin-Angiotensin System Studies

Cited by 207

Pulse wave velocity is associated with muscle mass decline: Health ABC study

study, F. T. H. A., Abbatecola, A. M., Chiodini, P., Gallo, C., Lakatta, E., Sutton-Tyrrell, K., Tylavsky, F. A., Goodpaster, B., de Rekeneire, N., Schwartz, A. V., et al. (2012) · AGE

Cardiovascular Health and Disease PreventionNutrition and Health in Aging

Cited by 114

Cholesterol, triglycerides, and the Five-Factor Model of personality

Sutin, A. R., Terracciano, A., Deiana, B., Uda, M., Schlessinger, D., Lakatta, E. G., & Costa Jr., P. T. (2010) · Biological Psychology

Personality Traits and PsychologyLipoproteins and Cardiovascular Health

Cited by 109

COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan

Tarasov, K. V., Sanna, S., Scuteri, A., Strait, J. B., Orrù, M., Parsa, A., Lin, P.-I., Maschio, A., Lai, S., Piras, M. G., et al. (2009) · Circulation: Cardiovascular Genetics

Cardiovascular Health and Disease PreventionGenetic Associations and Epidemiology

Cited by 104

Disulfiram Treatment Normalizes Body Weight in Obese Mice

Bernier, M., Mitchell, S. J., Wahl, D., Diaz, A., Singh, A., Seo, W., Wang, M., Ali, A., Kaiser, T., Price, N. L., et al. (2020) · Cell Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 85

Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy

Sanbe, A., James, J., Tuzcu, V., Nas, S., Martin, L., Gulick, J., Osinska, H., Sakthivel, S., Klevitsky, R., Ginsburg, K. S., et al. (2005) · Circulation

Cardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmias

Cited by 74