Cited by 292Stress Responses and CortisolMemory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Role of the medial prefrontal cortex in coping and resilience

Open access

Maier, Steven F., Watkins, Linda R.·2010·Brain Research

DOI 10.1016/j.brainres.2010.08.039PMC PMC2967290

Open this paper in CoChat — free account

Abstract

The degree of behavioral control that an organism has over an aversive event is well known to modulate the behavioral and neurochemical consequences of exposure to the event. Here we review recent research that suggests that the experience of control over a potent stressor alters how the organism responds to future aversive events as well as to the stressor being controlled. More specifically, subjects that have experienced control show blunted behavioral and neurochemical responses to subsequent stressors occurring days to months later. Indeed, these subjects respond as if a later uncontrollable stressor is actually controllable. Further, we review research indicating that the stress resistance induced by control depends on control-induced activation of ventral medial prefrontal cortical (vmPFC) inhibitory control over brainstem and limbic structures. Furthermore, there appears to be plasticity in these circuits such that the experience of control alters the vmPFC in such a way that later uncontrollable stressors now activate the vmPFC circuitry, leading to inhibition of stress-responsive limbic and brainstem structures, i.e., stressor resistance. This controllability-induced proactive stressor resistance generalizes across very different stressors and may be involved in determining individual difference in reactions to traumatic events.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.brainres.2010.08.039

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

An Integrative Theory of Prefrontal Cortex Function
Miller, E. K., & Cohen, J. D. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.167 · Cited by 12,803
Coping styles in animals: current status in behavior and stress-physiology
Koolhaas, J. M., Korte, S. M., De Boer, S. F., Van Der Vegt, B. J., Van Reenen, C. G., Hopster, H., De Jong, I. C., Ruis, M. A. W., & Blokhuis, H. J. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00026-3 · Cited by 2,875 · cited 1×
“At the animal level investigators have generally distinguished between active and passive coping styles (Koolhaas et al., 1999).”
Learned helplessness: Theory and evidence
Maier, S. F., & Seligman, M. E. (1976) · Journal of Experimental Psychology: General · doi:10.1037/0096-3445.105.1.3 · Cited by 2,494
Self-citation
Failure to escape traumatic shock.
Seligman, M. E., & Maier, S. F. (1967) · Journal of Experimental Psychology · doi:10.1037/h0024514 · Cited by 1,981 · cited 1×
“…our laboratory directed at these questions derives from older reports indicating that a session of ES prevented a later exposure to IS from producing shuttle box escape deficits (Seligman and Maier, 1967), even if the two experiences occurred in different environments (Williams and Maier, 1977).”
Self-citation
Differential projections of the infralimbic and prelimbic cortex in the rat
Vertes, R. P. (2004) · Synapse · doi:10.1002/syn.10279 · Cited by 1,550
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541
The amygdala
LeDoux, J. (2007) · Current Biology · doi:10.1016/j.cub.2007.08.005 · Cited by 1,281
The Psychobiology of Depression and Resilience to Stress: Implications for Prevention and Treatment
Southwick, S. M., Vythilingam, M., & Charney, D. S. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143948 · Cited by 1,160
Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults
Urry, H. L., van Reekum, C. M., Johnstone, T., Kalin, N. H., Thurow, M. E., Schaefer, H. S., Jackson, C. A., Frye, C. J., Greischar, L. L., Alexander, A. L., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3215-05.2006 · Cited by 1,056
A Functional Magnetic Resonance Imaging Study of Amygdala and Medial Prefrontal Cortex Responses to Overtly Presented Fearful Faces in Posttraumatic Stress Disorder
Shin, L. M., Wright, C. I., Cannistraro, P. A., Wedig, M. M., McMullin, K., Martis, B., Macklin, M. L., Lasko, N. B., Cavanagh, S. R., Krangel, T. S., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.273 · Cited by 960

Flagged first, then by citations

Show all 49 references

Sorted by citations

Items 101–200 of 291

Behavioral training and predisposed coping strategies interact to influence resilience in male Long-Evans rats: Implications for depression
Bardi, M., Rhone, A. P., Franssen, C. L., Hampton, J. E., Shea, E. A., Hyer, M. M., Huber, J., & Lambert, K. G. (2012) · Stress · doi:10.3109/10253890.2011.623739 · Cited by 38
Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test
Pereira, V. S., Suavinha, A. C. D. R., Wegener, G., & Joca, S. R. L. (2015) · Psychopharmacology · doi:10.1007/s00213-014-3853-2 · Cited by 37
Perceived life stress exposure modulates reward-related medial prefrontal cortex responses to acute stress in depression
Kumar, P., Slavich, G. M., Berghorst, L. H., Treadway, M. T., Brooks, N. H., Dutra, S. J., Greve, D. N., O’Donovan, A., Bleil, M. E., Maninger, N., et al. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.03.035 · Cited by 41
Resistance to antidepressant drugs
Willner, P., Scheel‐Krüger, J., & Belzung, C. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000066 · Cited by 36
Prefrontal mechanisms of comorbidity from a transdiagnostic and ontogenic perspective
MacDonald, A. N., Goines, K., Novacek, D. M., & Walker, E. F. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000742 · Cited by 40
Reduced adaptation of glutamatergic stress response is associated with pessimistic expectations in depression
Cooper, J. A., Nuutinen, M. R., Lawlor, V. M., DeVries, B. A. M., Barrick, E. M., Hossein, S., Cole, D. J., Leonard, C. V., Hahn, E. C., Teer, A. P., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23284-9 · Cited by 36
Functional lateralization of the medial prefrontal cortex in the modulation of anxiety in mice: Left or right?
Santos-Costa, N., Vicente, M. A., Cipriano, A. C., Miguel, T. T., & Nunes‐de‐Souza, R. L. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.04.011 · Cited by 35
Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABAergic Parvalbumin Interneurons Attenuates the Impact of Chronic Stress in Male Mice
Nawreen, N., Cotella, E. M., Morano, R. L., Mahbod, P., Dalal, K. S., Fitzgerald, M. E., Martelle, S. E., Packard, B. A., Franco, A. C. G., Moloney, R. D., et al. (2020) · eNeuro · doi:10.1523/eneuro.0423-19.2020 · Cited by 35
Interactions of the dorsal hippocampus, medial prefrontal cortex and nucleus accumbens in formation of fear memory: Difference in inhibitory avoidance learning and contextual fear conditioning
Yang, F., & Liang, K. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.07.017 · Cited by 33
Vesicular Glutamate Transporter 1 Knockdown in Infralimbic Prefrontal Cortex Augments Neuroendocrine Responses to Chronic Stress in Male Rats
Myers, B., McKlveen, J. M., Morano, R. L., Ulrich‐Lai, Y. M., Solomon, M. B., Wilson, S. P., & Herman, J. P. (2017) · Endocrinology · doi:10.1210/en.2017-00426 · Cited by 33
Integrative Brain Dynamics in Childhood Bullying Victimization: Cognitive and Emotional Convergence Associated With Stress Psychopathology
Palamarchuk, I. S., & Vaillancourt, T. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.782154 · Cited by 38
Activity in a prefrontal-periaqueductal gray circuit overcomes behavioral and endocrine features of the passive coping stress response
Johnson, S. B., Lingg, R. T., Skog, T. D., Hinz, D. C., Romig‐Martin, S. A., Viau, V., Narayanan, N. S., & Radley, J. J. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2210783119 · Cited by 35
Drunken Environments: A Survey of Bartenders Working in Pubs, Bars and Nightclubs
Tutenges, S., Bøgkjær, T., Witte, M., & Hesse, M. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10104896 · Cited by 30
Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence
Gee, D. G., Sisk, L. M., Cohodes, E. M., & Bryce, N. V. (2022) · Nature Communications · doi:10.1038/s41467-022-33416-4 · Cited by 36
Goal-Driven Cognition in the Brain: A Computational FrameworkPreprint
O’Reilly, R. C., Hazy, T. E., Mollick, J., Mackie, P., & Herd, S. A. (2014) · arXiv (Cornell University) · doi:10.48550/arxiv.1404.7591 · Cited by 54
Prediction of Learned Resistance or Helplessness by Hippocampal-Prefrontal Cortical Network Activity during Stress
Marques, D. B., Ruggiero, R. N., Bueno-Júnior, L. S., Rossignoli, M. T., & Leite, J. P. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0128-21.2021 · Cited by 31
Activation of Infralimbic to Nucleus Accumbens Shell Pathway Suppresses Conditioned Aversion in Male But Not Female Rats
Hurley, S. W., & Carelli, R. M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0137-20.2020 · Cited by 29
Stress-induced impairments in prefrontal-mediated behaviors and the role of the N-methyl-d-aspartate receptor
Graybeal, C., Kiselycznyk, C., & Holmes, A. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.02.042 · Cited by 30
Psychoneuroendocrinology of Stress
Gunnar, M. R., Doom, J. R., & Esposito, E. A. (2015) · Wiley eBooks · doi:10.1002/9781118963418.childpsy304 · Cited by 29
Strain-Dependent Variations in Stress Coping Behavior Are Mediated by a 5-HT/GABA Interaction within the Prefrontal Corticolimbic System
Andolina, D., Maran, D., Viscomi, M. T., & Puglisi‐Allegra, S. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyu074 · Cited by 30
Effects of Stressor Predictability on Escape Learning and Sleep in Mice
Machida, M., Yang, L., Wellman, L. L., & Sanford, L. D. (2013) · SLEEP · doi:10.5665/sleep.2464 · Cited by 28
Interpersonal dysfunction in borderline personality: a decision neuroscience perspective
Hallquist, M. N., Hall, N. T., Schreiber, A., & Dombrovski, A. Y. (2017) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2017.09.011 · Cited by 28
Experiential learning as preparation for leadership
Waller, L., Reitz, M., Poole, E., RIDDELL, P. M., & Muir, A. J. (2017) · Leadership & Organization Development Journal · doi:10.1108/lodj-03-2015-0057 · Cited by 28
Stress-Induced Reduction of Dorsal Striatal D2 Dopamine Receptors Prevents Retention of a Newly Acquired Adaptive Coping Strategy
Campus, P., Canterini, S., Orsini, C., Fiorenza, M. T., Puglisi‐Allegra, S., & Cabib, S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00621 · Cited by 28
Sex- and Stress-Dependent Effects on Dendritic Morphology and Spine Densities in Putative Orexin Neurons
Grafe, L. A., Geng, E., Corbett, B., Urban, K., & Bhatnagar, S. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.08.026 · Cited by 25
Trophic Mechanisms for Exercise-Induced Stress Resilience: Potential Role of Interactions between BDNF and Galanin
Holmes, P. V. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00090 · Cited by 29
Detecting emotion in others: increased insula and decreased medial prefrontal cortex activation during emotion processing in elite adventure racers
Thom, N. J., Johnson, D. C., Flagan, T., Simmons, A. N., Kotturi, S., Orden, K. F. V., Potterat, E. G., Swain, J. L., & Paulus, M. P. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nss127 · Cited by 26
A systems-neuroscience model of phasic dopamine.
Mollick, J., Hazy, T. E., Krueger, K. A., Nair, A., Mackie, P., Herd, S. A., & O’Reilly, R. C. (2020) · Psychological Review · doi:10.1037/rev0000199 · Cited by 23
Social belonging: brain structure and function is linked to membership in sports teams, religious groups, and social clubs
Kieckhäfer, C., Schilbach, L., & Bzdok, D. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac351 · Cited by 29
Resilience in shock and swim stress models of depression
Drugan, R. C., Christianson, J. P., Warner, T. A., & Kent, S. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00014 · Cited by 24
Meeting the Psychological Health & Growth Needs of Black College Students: Culture, Resonance and Resilience
Helling, J., & Chandler, G. E. (2019) · Journal of College Student Psychotherapy · doi:10.1080/87568225.2019.1660291 · Cited by 23
Functional neuroimaging of resilience to trauma: convergent evidence and challenges for future research
Norbury, A., Seeley, S. H., Pérez-Rodríguez, M. M., & Feder, A. (2023) · Psychological Medicine · doi:10.1017/s0033291723001162 · Cited by 28
Long-term effects of intermittent early life stress on primate prefrontal–subcortical functional connectivity
Yuan, R., Nechvatal, J. M., Buckmaster, C. L., Ayash, S., Parker, K. J., Schatzberg, A. F., Lyons, D. M., & Menon, V. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-00956-0 · Cited by 22
The Protective Effects of Perceived Control During Repeated Exposure to Aversive Stimuli
Wang, K. S., & Delgado, M. R. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.625816 · Cited by 25
Dopamine/noradrenaline reuptake inhibition in women improves endurance exercise performance in the heat
Cordery, P., Peirce, N. S., Maughan, R. J., & Watson, P. (2016) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12753 · Cited by 24
Development and validation of the Dimensional Inventory of Stress and Trauma Across the Lifespan (DISTAL): A novel assessment tool to facilitate the dimensional study of psychobiological sequelae of exposure to adversity
Cohodes, E. M., McCauley, S., Pierre, J. C., Hodges, H. R., Haberman, J. T., Santiuste, I., Rogers, M. K., Wang, J., Mandell, J. D., & Gee, D. G. (2023) · Developmental Psychobiology · doi:10.1002/dev.22372 · Cited by 21
Taking the Perspective that a Depressive State Reflects Inflammation: Implications for the Use of Antidepressants
Littrell, J. L. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00297 · Cited by 22
Corticolimbic catecholamines in stress: a computational model of the appraisal of controllability
Fiore, V. G., Mannella, F., Mirolli, M., Latagliata, E. C., Valzania, A., Cabib, S., Dolan, R. J., Puglisi‐Allegra, S., & Baldassarre, G. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0727-7 · Cited by 21
Enhanced stimulus sequence-dependent repeated learning in male offspring after prenatal stress alone or in conjunction with lead exposure
Cory‐Slechta, D. A., Virgolini, M. B., Liu, S., & Weston, D. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.06.013 · Cited by 21
Naltrexone Acutely Enhances Connectivity Between the Ventromedial Prefrontal Cortex and a Left Frontoparietal Network
Elton, A., Dove, S., Spencer, C. N., Robinson, D. L., & Boettiger, C. A. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13999 · Cited by 20
Defeat-induced activation of the ventral medial prefrontal cortex is necessary for resistance to conditioned defeat
Morrison, K. E., Bader, L. R., McLaughlin, C. N., & Cooper, M. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.01.006 · Cited by 24
Autophagy status as a gateway for stress-induced catecholamine interplay in neurodegeneration
Fornai, F., & Puglisi‐Allegra, S. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.01.015 · Cited by 20
Effort-Based Reward (EBR) training enhances neurobiological efficiency in a problem-solving task: Insights for depression therapies
Bardi, M., True, M., Franssen, C. L., Kaufman, C., Rzucidlo, A., & Lambert, K. G. (2012) · Brain Research · doi:10.1016/j.brainres.2012.10.027 · Cited by 20
Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress
McGovern, D. J., Ly, A., Ecton, K. L., Huynh, D. T., Prévost, E. D., Gonzalez, S. C., McNulty, C. J., Rau, A. R., Hentges, S. T., Daigle, T. L., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01858-3 · Cited by 20
Neural habituation during acute stress signals a blunted endocrine response and poor resilience
Liu, Y., Zhao, X., Hu, W., Ren, Y., Wei, Z., Ren, X., Tang, Z., Wang, N., Chen, H., Yi-zhuo, L., et al. (2023) · Psychological Medicine · doi:10.1017/s0033291723001666 · Cited by 21
Risk for anxiety and implications for treatment: developmental, environmental, and genetic factors governing fear regulation
Hartley, C. A., & Casey, B. J. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12287 · Cited by 21
Don't stress, it's under control: Neural correlates of stressor controllability in humans
Meine, L. E., Meier, J., Meyer, B., & Wessa, M. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118701 · Cited by 21
Insula-cortico-subcortical networks predict interoceptive awareness and stress resilience
Fermin, A. S. R., Sasaoka, T., Maekawa, T., Ono, K., Chan, H.-L., & Yamawaki, S. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.103991 · Cited by 20
Distinct behavioral consequences of stress models of depression in the elevated T-maze
Soares-Rachetti, V. D. P., Vicente, M. A., Biojone, C., Zangrossi, H., Guimarães, F. S., & Joca, S. R. L. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.08.032 · Cited by 18
Characterizing experiential elements of early-life stress to inform resilience: Buffering effects of controllability and predictability and the importance of their timing
Cohodes, E. M., Sisk, L. M., Keding, T. J., Mandell, J. D., Notti, M. E., & Gee, D. G. (2023) · Development and Psychopathology · doi:10.1017/s0954579423000822 · Cited by 21
Sleep and subjective well-being among chinese adolescents
An, Y., Ji, X., Zhou, L., & Liu, J. (2023) · Asian Journal of Social Health and Behavior · doi:10.4103/shb.shb_238_23 · Cited by 18
Development of social play in hamsters: Sex differences and their possible functions
Kyle, S. C., Burghardt, G. M., & Cooper, M. A. (2019) · Brain Research · doi:10.1016/j.brainres.2019.02.012 · Cited by 17
Modulation of neuroplasticity-related targets following stress-induced acute escape deficit
Benatti, C., Radighieri, G., Alboni, S., Blom, J. M. C., Brunello, N., & Tascedda, F. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.02.023 · Cited by 18
Loss of control over mild aversive events produces significant helplessness in mice
Yao, L., Li, Y., Qian, Z., Wu, M., Yang, H., Chen, N., Qiao, Y., Wei, C., Zheng, Q., Han, J., et al. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112173 · Cited by 18
Functional networks activated by controllable and uncontrollable stress in male and female rats
Worley, N. B., Everett, S., Foilb, A. R., & Christianson, J. P. (2020) · Neurobiology of Stress · doi:10.1016/j.ynstr.2020.100233 · Cited by 17
Sex moderates family history of alcohol use disorder and childhood maltreatment effects on an fMRI stop‐signal task
Elton, A., Allen, J. M., Yorke, M., Khan, F. A., Xu, P., & Boettiger, C. A. (2023) · Human Brain Mapping · doi:10.1002/hbm.26221 · Cited by 16
Susceptibility and Resilience to PTSD-Like Symptoms in Mice Are Associated with Opposite Dendritic Changes in the Prelimbic and Infralimbic Cortices Following Trauma
Lguensat, A., Bentefour, Y., Bennis, M., Ba-M’hamed, S., & Garcia, R. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.08.018 · Cited by 16
‘Give-up-itis’ revisited: Neuropathology of extremis
Leach, J. (2018) · Medical Hypotheses · doi:10.1016/j.mehy.2018.08.009 · Cited by 16
Acute coronary syndrome-associated depression: The salience of a sickness response analogy?
Smith, I. G., Parker, G. B., Cvejic, E., & Vollmer-Conna, U. S. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.02.025 · Cited by 15
Neurocognitive improvements after best-practice intervention for chronic fatigue syndrome: Preliminary evidence of divergence between objective indices and subjective perceptions
Cvejic, E., Lloyd, A. R., & Vollmer-Conna, U. S. (2016) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2016.02.002 · Cited by 15
Psychotic-Like Experiences and Suicidal Ideation Among Adolescents: The Chain Mediating Role of Insomnia Symptoms and Resilience
Luo, X., Yu, T., Yang, Z., & Wang, D. (2023) · Psychology Research and Behavior Management · doi:10.2147/prbm.s426363 · Cited by 15
Acute coronary syndrome and depression: A review of shared pathophysiological pathways
Smith, I. G., Parker, G. B., Rourke, P., Cvejic, E., & Vollmer-Conna, U. S. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415597304 · Cited by 16
Coping strategies within a personality space
Gárriz, M., Gutiérrez, F., Peri, J. M., Baillés, E., & Torrúbia, R. (2015) · Personality and Individual Differences · doi:10.1016/j.paid.2015.02.024 · Cited by 18
Resilience to fear: The role of individual factors in amygdala response to stressors
Fonseca, R., Madeira, N., & Simões, C. R. B. (2020) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2020.103582 · Cited by 17
Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?
McCormick, C. M. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_245 · Cited by 14
Kappa opioid receptor antagonism protects working memory performance from mild stress exposure in Rhesus macaques
Wallace, T. L., Martin, W. J., & Arnsten, A. F. T. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100493 · Cited by 14
Inhibitory control and mood in relation to psychological resilience: an ecological momentary assessment study
Nahum, M., Sinvani, R.-T., Afek, A., Ben-Avraham, R., Jordan, J. T., Ben‐Shachar, M. S., Yehuda, A. B., Cohen, N., Davidov, A., & Gilboa, Y. (2023) · Scientific Reports · doi:10.1038/s41598-023-40242-1 · Cited by 16
Coping with the multifaceted and multifunctional role of cortisol in the brain
de Kloet, E. R. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104047 · Cited by 18
The Cambridge Handbook of the Development of Coping
Skinner, E. A., Zimmer‐Gembeck, M. J., Aldwin, C. M., Kurth, M., Brockmann, A., Lee, H. S., Magro, S. W., VanMeter, F., Roisman, G. I., Raftery-Helmer, J. N., et al. (2023) · Cambridge University Press eBooks · doi:10.1017/9781108917230 · Cited by 14
Self-citation
Seven Guideposts to the Study of Perceived Control Across the Lifespan
Skinner, E. A. (2016) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780190257040.003.0013 · Cited by 15
Strong interactions between learned helplessness and risky decision-making in a rat gambling model
Nóbrega, J. N., Hedayatmofidi, P. S., & Lobo, D. S. S. (2016) · Scientific Reports · doi:10.1038/srep37304 · Cited by 14
Stress: Influences and Determinants of Psychopathology
Pereira-Figueiredo, I., & Umeoka, E. H. L. (2024) · Encyclopedia · doi:10.3390/encyclopedia4020066 · Cited by 14
Resilience to chronic mild stress-induced anhedonia preserves the ability of the ventral hippocampus to respond to an acute challenge
Brivio, P., Gallo, M. T., Gruca, P., Łasoń, M., Litwa, E., Fumagalli, F., Papp, M., & Calabrese, F. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01470-0 · Cited by 13
Oxytocin modulation in the medial prefrontal cortex of pair-exposed rats during fear conditioning
Jang, M., Jung, T., Jeong, Y., Byun, Y., & Noh, J. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105752 · Cited by 13
Central vasopressin V1A receptor blockade alters patterns of cellular activation and prevents glucocorticoid habituation to repeated restraint stress exposure
Gray, M. E., Innala, L., & Viau, V. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000935 · Cited by 12
Learned helplessness and learned controllability: from neurobiology to cognitive, emotional and behavioral neurosciences
Tafet, G. E., & Alonso, T. O. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1600165 · Cited by 22
Resilience, sleep quality and sleepiness in Peruvian medical students: a multicenter study
Zila-Velasque, J. P., Grados‐Espinoza, P., Caira‐Chuquineyra, B., Díaz-Vargas, M., Calderón, G. S. S., Choquegonza, S., Temoche-Rivas, M. S., Peixoto, K. S., Valladares-Garrido, M. J., & Failoc‐Rojas, V. E. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1284716 · Cited by 11
Neurophysiological response to social feedback in stressful situations
Balconi, M., Angioletti, L., & Rovelli, K. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16528 · Cited by 12
Dominance status alters restraint-induced neural activity in brain regions controlling stress vulnerability
Cooper, M. A., Seddighi, S., Barnes, A., Grizzell, J. A., Dulka, B. N., & Clinard, C. T. (2017) · Physiology & Behavior · doi:10.1016/j.physbeh.2017.06.003 · Cited by 12
Effects of Ethanol Exposure and Withdrawal on Neuronal Morphology in the Agranular Insular and Prelimbic Cortices: Relationship with Withdrawal-Related Structural Plasticity in the Nucleus Accumbens
Frost, M. E., Peterson, V. L., Bird, C. W., McCool, B. A., & Hamilton, D. A. (2019) · Brain Sciences · doi:10.3390/brainsci9080180 · Cited by 11
Interactions Between Experience, Genotype and Sex in the Development of Individual Coping Strategies
Ventura, R., Cabib, S., Babicola, L., Andolina, D., Segni, M. D., & Orsini, C. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.785739 · Cited by 11
Role of Stress-Related Dopamine Transmission in Building and Maintaining a Protective Cognitive Reserve
Cabib, S., Latagliata, E. C., & Orsini, C. (2022) · Brain Sciences · doi:10.3390/brainsci12020246 · Cited by 12
Effects of inescapable versus escapable social stress in Syrian hamsters: The importance of stressor duration versus escapability
McCann, K. E., Bicknese, C. N., Norvelle, A., & Huhman, K. L. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.02.039 · Cited by 12
Neural effects of controllability as a key dimension of stress exposure
Cohodes, E. M., Odriozola, P., Mandell, J. D., Caballero, C., McCauley, S., Zacharek, S. J., Hodges, H. R., Haberman, J. T., Smith, M., Thomas, J., et al. (2022) · Development and Psychopathology · doi:10.1017/s0954579421001498 · Cited by 11
Chronic stress and anticipatory event-related potentials: the moderating role of resilience
Shi, X., & Wu, J. (2020) · Stress · doi:10.1080/10253890.2020.1766019 · Cited by 12
A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response
Bambico, F. R., Li, Z., Creed, M. C., Gregorio, D. D., Diwan, M., Li, J. L., McNeill, S., Gobbi, G., Raymond, R., & Nóbrega, J. N. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz187 · Cited by 12
Monoacylglycerol lipase alpha inhibition alters prefrontal cortex excitability and blunts the consequences of traumatic stress in rat
Worley, N. B., Varela, J. A., Gaillardetz, G. P., Hill, M. N., & Christianson, J. P. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.107964 · Cited by 11
Prefrontal 5α-reductase 2 mediates male-specific acute stress response
Cadeddu, R., Braccagni, G., Floris, G., Branca, C., Corridori, E., Salviati, S., Sánchez, P., Santovito, L. S., Torres, J. M., Ortega, E., et al. (2025) · Science Advances · doi:10.1126/sciadv.adr0563 · Cited by 9
Cognitive performance improvement in Canadian Armed Forces personnel during deployment
Makhani, A., Akbaryan, F., & Černak, I. (2015) · Journal of Military Veteran and Family Health · doi:10.3138/jmvfh.2014-04 · Cited by 11
Spaced sessions of avoidance extinction reduce spontaneous recovery and promote infralimbic cortex activation
Tapias-Espinosa, C., Kádár, E., & Segura-Torres, P. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.08.025 · Cited by 11
Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3
Nashed, M. G., Waye, S., Hasan, S. M. N., Nguyen, D., Wiseman, M., Zhang, J., Lau, H., Dinesh, O. C., Raymond, R., Greig, I. R., et al. (2022) · Psychopharmacology · doi:10.1007/s00213-021-06045-w · Cited by 9
Incident experience predicts freezing-like responses in firefighters
Ly, V., Roijendijk, L., Hazebroek, H., Tonnaer, C., & Hagenaars, M. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186648 · Cited by 13
Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic
Perellón‐Alfonso, R., Redondo‐Camós, M., Abellaneda‐Pérez, K., Cattaneo, G., Delgado‐Gallén, S., España‐Irla, G., Sánchez, J. S., Tormos, J. M., Pascual‐Leone, Á., & Bartrés‐Faz, D. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e10208 · Cited by 10
Low mindfulness is related to poor sleep quality from middle adolescents to emerging adults: a process model involving resilience and emotional dysfunction
Zhou, H., Zhu, Z., Feng, X., & Zhang, R. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05092-1 · Cited by 10
Making and breaking habits: Revisiting the definitions and behavioral factors that influence habits in animals
Handel, S. N., & Smith, R. J. (2023) · Journal of the Experimental Analysis of Behavior · doi:10.1002/jeab.889 · Cited by 10
Brief stress impairs recognition memory through amygdalar activation in animals with medial prefrontal cortex lesions
Park, J.-C., Jeon, Y.-J., Kim, J. J., Cho, J., Choi, D.-H., & Han, J. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135245 · Cited by 8
Neurophysiologic Reactions during Heart Rate Variability Biofeedback Session in Adolescents with Different Risk of Internet Addiction
Demin, D. B., & Poskotinova, L. V. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19052759 · Cited by 8
Involvement of P2X2 receptor in the medial prefrontal cortex in ATP modulation of the passive coping response to behavioral challenge
Kong, Y., Wang, Q., Wu, D., Hu, J., Zang, W., Li, X., Yang, J., & Gao, T. (2020) · Genes Brain & Behavior · doi:10.1111/gbb.12691 · Cited by 7
Extracurricular activity participation in early adolescence predicts coping efficacy one year later
Heaslip, G. P., Davis, H. L., & Barber, B. L. (2021) · Australian Journal of Psychology · doi:10.1080/00049530.2021.1884000 · Cited by 7
Neural correlates linking trauma and physical symptoms
Choi, J. J., Martins, J. S., Hwang, S., Sinha, R., & Seo, D. (2022) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2022.111560 · Cited by 7

Authors: Maier, S. F., & Watkins, L. R.
Affiliations: University of Colorado Boulder (US)
Corresponding author: Maier, Steven F.
ORCID: Maier, Steven F.
Watkins, Linda R.
Venue: Brain Research
Publisher: Elsevier BV
Published: 2010-10
Volume: 1355
Pages: 52-60
ISSN: 0006-8993 (ISSN-L)
DOI: 10.1016/j.brainres.2010.08.039
PMC: PMC2967290
OpenAlex: W1999655743
Cited by: 292
References: 49
Citations by year: 2026: 12 · 2025: 14 · 2024: 15 · 2023: 20 · 2022: 21 · 2021: 15 · 2020: 23 · 2019: 20 · 2018: 7 · 2017: 19 · 2016: 23 · 2015: 22 · 2014: 23 · 2013: 24 · 2012: 22
FWCI: 7.79
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Brain Research (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (MH50479)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: medial prefrontal cortex, stress resilience, perceived control, coping, ventromedial prefrontal cortex, inhibitory control, brainstem, limbic system, neuroplasticity, individual differences, trauma, aversive events
MeSH terms: Adaptation, Psychological, Animals, Brain Stem, Humans, Limbic System, Neural Inhibition, Neural Pathways, Neuronal Plasticity, Stress, Psychological, Prefrontal Cortex, Resilience, Psychological

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Role of the medial prefrontal cortex in coping and resilience

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks