Watkins, Linda R.

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000) · Nature

Vagus Nerve Stimulation ResearchImmune Response and Inflammation

Cited by 4,211

Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

Maier, S. F., & Watkins, L. R. (1998) · Psychological Review

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 1,130

Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

Amat, J., Baratta, M. V., Paul, E., Bland, S. T., Watkins, L. R., & Maier, S. F. (2005) · Nature Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 931

Organization of endogenous opiate and nonopiate pain control systems

Watkins, L. R., & Mayer, D. J. (1982) · Science

Pain Mechanisms and TreatmentsNeuropeptides and Animal Physiology

Cited by 791

Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor.

Maier, S. F., & Watkins, L. R. (2005) · Neuroscience & Biobehavioral Reviews

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 737

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

Ledeboer, A., Sloane, E. M., Milligan, E. D., Frank, M. G., Mahony, J. H., Maier, S. F., & Watkins, L. R. (2005) · Pain

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 677

Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states

Watkins, L. R., Maier, S. F., & Goehler, L. E. (1995) · Pain

Pain Mechanisms and TreatmentsTryptophan and brain disorders

Cited by 659

Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses

Frank, M. G., Baratta, M. V., Sprunger, D. B., Watkins, L. R., & Maier, S. F. (2007) · Brain Behavior and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 578

Vagal immune-to-brain communication: a visceral chemosensory pathway

Goehler, L. E., Gaykema, R. P. A., Hansen, M. K., Anderson, K., Maier, S. F., & Watkins, L. R. (2000) · Autonomic Neuroscience

Vagus Nerve Stimulation ResearchHeart Rate Variability and Autonomic Control

Cited by 525

Exposure to Acute Stress Induces Brain Interleukin-1β Protein in the Rat

Nguyen, K. T., Deak, T., Owens, S. M., Kohno, T., Fleshner, M., Watkins, L. R., & Maier, S. F. (1998) · The Journal of Neuroscience

Stress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms

Cited by 460

The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia

Watkins, L. R., Hutchinson, M. R., Rice, K. C., & Maier, S. F. (2009) · Trends in Pharmacological Sciences

Pain Mechanisms and TreatmentsPain Management and Opioid Use

Cited by 438

The Pain of Being Sick: Implications of Immune-to-Brain Communication for Understanding Pain

Watkins, L. R., & Maier, S. F. (2000) · Annual Review of Psychology

Pain Mechanisms and TreatmentsTryptophan and brain disorders

Cited by 388

Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward

Hutchinson, M. R., Bland, S. T., Johnson, K. W., Rice, K. C., Maier, S. F., & Watkins, L. R. (2007) · The Scientific World JOURNAL

Pain Mechanisms and TreatmentsNeuropeptides and Animal Physiology

Cited by 359

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

Frank, M. G., Barrientos, R. M., Biedenkapp, J. C., Rudy, J. W., Watkins, L. R., & Maier, S. F. (2006) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 327

Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses

Frank, M. G., Thompson, B. M., Watkins, L. R., & Maier, S. F. (2012) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 310

A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats

Chacur, M., Milligan, E. D., Gazda, L. S., Armstrong, C., Wang, H., Tracey, K. J., Maier, S. F., & Watkins, L. R. (2001) · Pain

Pain Mechanisms and TreatmentsPain Management and Treatment

Cited by 309

Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide

Frank, M. G., Miguel, Z. D., Watkins, L. R., & Maier, S. F. (2010) · Brain, Behavior, and Immunity

Stress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms

Cited by 303

Role of the medial prefrontal cortex in coping and resilience

Maier, S. F., & Watkins, L. R. (2010) · Brain Research

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 292

Selective Effects of Peripheral Lipopolysaccharide Administration on Contextual and Auditory-Cue Fear Conditioning

Pugh, C. R., Kumagawa, K., Fleshner, M., Watkins, L. R., Maier, S. F., & Rudy, J. W. (1998) · Brain, Behavior, and Immunity

Memory and Neural MechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 286

Prior Stressor Exposure Sensitizes LPS-Induced Cytokine Production

Johnson, J. D., O'Connor, K. A., Deak, T., Stark, M., Watkins, L. R., & Maier, S. F. (2002) · Brain, Behavior, and Immunity

Stress Responses and CortisolTryptophan and brain disorders

Cited by 270

Brain-Derived Neurotrophic Factor MRNA Downregulation Produced by Social Isolation Is Blocked by Intrahippocampal Interleukin-1 Receptor Antagonist

Barrientos, R. M., Sprunger, D. B., Campeau, S., Higgins, E. A., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2003) · Neuroscience

Memory and Neural MechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 251

Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition

Bilbo, S. D., Biedenkapp, J. C., Der-Avakian, A., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2005) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 251

Previous Experience with Behavioral Control over Stress Blocks the Behavioral and Dorsal Raphe Nucleus Activating Effects of Later Uncontrollable Stress: Role of the Ventral Medial Prefrontal Cortex

Amat, J., Paul, E., Zarza, C., Watkins, L. R., & Maier, S. F. (2006) · The Journal of Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 249

Peripheral and central proinflammatory cytokine response to a severe acute stressor

O'Connor, K. A., Johnson, J. D., Hansen, M. K., Wieseler Frank, J. L., Maksimova, E., Watkins, L. R., & Maier, S. F. (2003) · Brain Research

Stress Responses and CortisolTryptophan and brain disorders

Cited by 247