Cited by 371Seaweed-derived Bioactive CompoundsPolysaccharides Composition and ApplicationsMarine and coastal plant biology

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Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity

Yuan, Yuan, Macquarrie, Duncan·2015·Carbohydrate Polymers

DOI 10.1016/j.carbpol.2015.04.057

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Abstract

Sulfated polysaccharides (fucoidan) from brown seaweed Ascophyllum nodosum were extracted by microwave assisted extraction (MAE) technology. Different conditions of temperature (90-150°C), extraction time (5-30 min) were evaluated and optimal fucoidan yield was 16.08%, obtained from 120°C for 15 min's extraction. Compositional analysis, GPC, HPAEC and IR analysis were employed for characterization of extracted sulfated polysaccharides. Fucose was the main monosaccharide of fucoidan extracted at 90°C while glucuronic acid was the main monosaccharide of fucoidan extracted at 150°C. Both the molecular weight and sulfate content of extracted fucoidan increased with decreasing extraction temperature. All fucoidans exhibited antioxidant activities as measured by DPPH scavenging and reducing power, among which fucoidan extracted at 90°C was highest. This study shows that MAE is an efficient technology to extract sulfated polysaccharides from seaweed and Ascophyllum nodosum could potentially be a resource for natural antioxidants.

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Authors: Yuan, Y., & Macquarrie, D.
Affiliations: University of York (GB)
Corresponding author: Macquarrie, Duncan
ORCID: Yuan, Yuan
Macquarrie, Duncan
Venue: Carbohydrate Polymers
Publisher: Elsevier BV
Published: 2015-09
Volume: 129
Pages: 101-107
ISSN: 0144-8617 (ISSN-L)
DOI: 10.1016/j.carbpol.2015.04.057
OpenAlex: W317714569
Semantic Scholar: fe72b2f1446aba29dd8e23236f0f0027211ea81a
Cited by: 371
References: 50
Citations by year: 2026: 23 · 2025: 45 · 2024: 39 · 2023: 43 · 2022: 35 · 2021: 44 · 2020: 36 · 2019: 31 · 2018: 25 · 2017: 25 · 2016: 16 · 2015: 9
FWCI: 38.85
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Carbohydrate Polymers (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
Keywords: fucoidan, sulfated polysaccharides, Ascophyllum nodosum, brown algae, microwave-assisted extraction, extraction temperature, extraction time, fucose, glucuronic acid, sulfate content, molecular weight, antioxidant activity, DPPH radical scavenging, reducing power, natural antioxidants
MeSH terms: Antioxidants, Biphenyl Compounds, Carbohydrates, Microwaves, Oxidation-Reduction, Picrates, Polysaccharides, Temperature, Time Factors, Uronic Acids, Free Radical Scavengers, Ascophyllum

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Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity

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