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Biosynthesis of agar in red seaweeds: A review
Abstract
Agar is a jelly-like biopolymer synthesized by many red seaweeds as their major cell wall component. Due to its excellent rheological properties, it has been exploited commercially for applications in food, cosmetic, pharmaceutical, biomedical and biotechnology industries. Despite its multiple uses, the biosynthesis of this phycocolloid is not fully understood. The current knowledge on agar biosynthesis is inferred from plant biochemistry and putative pathways for ulvan and alginate biosynthesis in green and brown seaweeds, respectively. In this review, the gaps in our current knowledge on agar biosynthetic pathway are discussed, focusing on the biosynthesis of agar precursors, elongation of agar polysaccharide chain and side chain modification. The development of molecular markers for the screening of desired seaweeds for industrial exploitation is also discussed.
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“However, the use of agar in the R&D industry, as well as in microbiological and analytical laboratories, is really widespread, mainly for the preparation of culture media compatible with a wide variety of cell lines [105].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [105]
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Metadata
- Authors
- Lee, W.-K., Lim, Y.-Y., Leow, A. T.-C., Namasivayam, P., Ong Abdullah, J., & Ho, C.-L.
- Affiliations
- Universiti Putra Malaysia (MY)
- Corresponding author
- Ho, Chai-Ling
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 164
- Pages
- 23-30
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2580382502
- Cited by
- 236
- References
- 110
- Citations by year
- 2026: 19 · 2025: 22 · 2024: 39 · 2023: 43 · 2022: 35 · 2021: 26 · 2020: 23 · 2019: 12 · 2018: 13 · 2017: 4
- FWCI
- 1.47
- Type
- journal article
- Language
- en
- Update notices
- erratum (2017-08-01)
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- PubMed (publishedVersion)
- Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) (acceptedVersion)
- Funders
- Kementerian Sains, Teknologi dan Inovasi (02-01-04-SF1282)
- Universiti Putra Malaysia (GP-IPS/2016/9487700)
- Kementerian Pendidikan Malaysia
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Keywords
- red seaweed, phycocolloids, side chain modification, alginate biosynthesis, seaweed cell wall, molecular markers
- MeSH terms
- Agar, Seaweed, Biosynthetic Pathways
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