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Cited by 1,862

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

The Microenvironmental Landscape of Brain Tumors

Open access
Quail, Daniela F., Joyce, Johanna A.·2017·Cancer Cell

Abstract

The brain tumor microenvironment (TME) is emerging as a critical regulator of cancer progression in primary and metastatic brain malignancies. The unique properties of this organ require a specific framework for designing TME-targeted interventions. Here we discuss a number of these distinct features, including brain-resident cell types, the blood-brain barrier, and various aspects of the immune-suppressive environment. We also highlight recent advances in therapeutically targeting the brain TME in cancer. By developing a comprehensive understanding of the complex and interconnected microenvironmental landscape of brain malignancies we will greatly expand the range of therapeutic strategies available to target these deadly diseases.

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Crossref · 10.1016/j.ccell.2017.02.009

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Metadata

Authors
Quail, D. F., & Joyce, J. A.
Venue
Cancer Cell
Publisher
Elsevier BV
Published
2017-03
Volume
31
Issue
3
Pages
326-341
ISSN
1535-6108 (ISSN-L)
OpenAlex
W2595863515
Cited by
1,862
References
43
FWCI
56.47
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Microenvironmental Landscape of Brain Tumors. https://app.cochat.ai/papers/10.1016/j.ccell.2017.02.009
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Quail, D. F., & Joyce, J. A. (2017). The Microenvironmental Landscape of Brain Tumors. Cancer Cell. https://doi.org/10.1016/j.ccell.2017.02.009

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.