O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate

Cited by (442)

Items 401–442 of 442

1. Hyaluronic acid optimizes therapeutic effects of Hydrogen peroxide-induced oxidative stress on breast cancer
   Ardeshir Abbasi, Nafiseh Pakravan, Zuhair M Hassan · 2020
2. Modulation of antioxidant enzyme B166 isoforms 1 and 5 expressions by SREBP1-a links ROS elimination to lipid metabolism in glioblastoma cells
   Cindy Cheung, Fanhua Kong, Bing‐Wu Wang · 2023 · Research Square
3. Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
   Michiko Miyakawa, Songbai Zhang, Jinan Behnan, Claudia Morganti, Keisuke Ito, Pauline Isaksn, Ayako Miyakawa, Per Uhlén · 2023 · Preprints.org
4. Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent
   Andrea Vallés‐Martí, Franziska Böttger, Elysia Yau, Khadija Tejjani, Loes A. M. Meijs, Sugandhi Sharma, Madiha Mumtaz, Tessa Y. S. Le Large, Leyla Ayse Erozenci, Daniëlle Dekker et al. · 2024 · eLife
5. In vivo anti-tumor activity of high-dose parenteral ascorbic acid is mediated primarily via cofactor activity, not via oxidative stress
   Talia Akram, Rebecca A. Luchtel, Vinay Dubey, Soma Seal, Ritesh Kumar Aggarwal, Hiroaki Sai, Niraj Konchady Shenoy · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
6. Examining the markers of vitamin C cytotoxicity in pancreatic ductal adenocarcinoma
   Cassia Warren · 2019 · cIRcle (University of British Columbia)
7. A systems pharmacology model to improve clinical outcomes in non-small cell lung cancer
   Benjamin Karl Schneider · 2020 · Iowa State University Digital Repository (Iowa State University)
8. Introduction
   Wang Jae Lee · 2019 · Springer eBooks
9. Cancer
   Wang Jae Lee · 2019 · Springer eBooks
10. Anti-Cancer and Stress Response Pathway Effects of Nanosilver and Sodium Ascorbate
    Shana J. Cameron · 2022 · Carleton University's Institutional Repository (MacOdrum Library, Carleton University)
11. Vitamin C: is there a place in anticancer treatment?
    Ivan Gerk, V. M. Moiseenko · 2022 · Practical oncology
12. A Vitamin C Renal Leak in Fabry Disease: The Rare Informs the Common
    Daniel Monti · 2023 · Journal of Nutrition
13. EVOLUTION OF IDEAS ABOUT THE ROLE OF VITAMINS AND SUPPLEMENTS IN THE DIET OF PATIENTS WITH CANCER
    V.I. Vdovychenko, V.V. Kulchytsky, T.V. Ostroglyad · 2021 · Україна Здоров’я нації
14. Iron Metabolism and Ferroptosis
    Hao Zheng, Shinya Toyokuni · 2023 · Springer eBooks
15. Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent
    Andrea Vallés‐Martí, Franziska Böttger, Elysia Yau, Khadija Tejjani, Loes A. M. Meijs, Sugandhi Sharma, Madiha Mumtaz, Tessa Y. S. Le Large, Leyla Ayse Erozenci, Daniëlle Dekker et al. · 2024 · eLife
16. DNA methylation in T cell leukaemia
    Maike Bensberg · 2024 · Linköping University medical dissertations
17. Author Response: Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent
    Andrea Vallés‐Martí, Franziska Böttger, Elysia Yau, Khadija Tejjani, Loes A. M. Meijs, Sugandhi Sharma, Madiha Mumtaz, Tessa Y. S. Le Large, Leyla Ayse Erozenci, Daniëlle Dekker et al. · 2024 · eLife
18. Combination Therapy with Pharmacological Ascorbate and Rucosopasem Selectively Radiosensitizes Colorectal Tumors to Clinically Relevant Radiation Doses
    Benjamin N. George, Casey F. Pulliam, Michael S. Petronek, Sarah A. King, Krishna Awasthi, Melissa A. Fath, Brianne R. O’Leary, Bradley T. Loeffler, Douglas R. Spitz, Michelle E. Howard et al. · 2026 · Radiation Research
19. Nutraceuticals
    Nancy Scanlan · 2025 · Veterinary Clinics of North America Small Animal Practice
20. Radical TTM-DMODPA for Ascorbic Acid Non-Catalytic Visual Detection
    Qingmei Zhong, Huijuan Zong, Xiaohui Xie, Xiaomei Rong, Chuan Yan · 2025 · Chemosensors
21. Application of biomaterials in long-circulating nanomicelles for anticancer therapy
    Najwa Mohamad, Kai Bin Liew, Muhammad Redza Fahmi Mod Razif, Ahmad Rashidi Mohamed Tahir, Fashli Syafiq Abd Razak · 2025 · Elsevier eBooks
22. Vitamin C Selectively Inhibits Kidney Renal Clear Cell Carcinoma Cell Growth by Suppressing the HIF-1 Pathway
    Che Wang, Yaoyang Zhou, Yulong Liang, Jue Pan, Jinyu Qiao, Lingbo Chen, Silin Liu, Jie Chen, Jin Wang, Xiao Sun et al. · 2025 · OncoTargets and Therapy
23. Polyphenols in Combination with Redox Active Nanoparticles as Enhancers of Ascorbic Acid Suppressive Effect in Fibrosarcoma L929 Cells
    Nataliya S. Kavok, Galyna Dudetskaya, Vladyslav V. Seminko, Pavel O. Maksimchuk, Yurii G. Kot, Vladimir Klochkov, Olga Sedyh · 2025 · IEEE International Conference Nanomaterials: Applications & Properties (NAP)
24. Small molecular weight polyfluoroalkyl phosphonates induce ROS-mediated cytotoxicity in glioblastoma cells: a molecular mechanism study
    Patryk Wołodkiewicz, Michał Juszczak, Paweł Tokarz, Katarzyna Woźniak, Paulina Tokarz · 2025 · Scientific Reports
25. Exploiting vitamin C as a prooxidant to activate ROS-responsive prodrugs for potent and selective tumor killing
    Taufeeque Ali, Thilini Nimasha Fernando Ponnamperumage, Cody Joshua Miller, Daniel Li, Wasiu Olaniyi Awoyera, Alexis Kimberly Peterson, Hanlun Gao, Jatin Pandey, Julia Anna Rose Jakusz, Heli Fan et al. · 2026 · Redox Biology
26. Additional file 1 of Alternative medicine: therapeutic effects on gastric original signet ring carcinoma via ascorbate and combination with sodium alpha lipoate
    Weiyu Chen, Lingyun Xu, Edwin Chang, Gayatri Gowrishankar, Katherine W. Ferrara, Sanjiv Sam Gambhir · 2022 · Figshare
27. Additional file 1 of All-in-one approaches for triple-negative breast cancer therapy: metal-phenolic nanoplatform for MR imaging-guided combinational therapy
    Xie, Qi, Li, Shichao, Feng, Xingxing, Shi, Jingyu, Li, Yang, Yuan, Guanjie, Yang, Conglian, Shen, Yaqi, Kong, Li, Zhang, Zhiping · 2022 · Figshare
28. Pharmacological Vitamin C Plus Oncolytic Adenoviruses Orchestrate Immunogenic Tumor Ferroptosis
    Yong Zhang, Hong Yang, Miao Chen, Bin Zhao, Haitao Zhang, Xu Gao, Peidong Chen, Zhi‐Wu Wang, Li Feng · 2026 · Journal of Medical Virology
29. Targeted Cancer Therapy Has Been Defined at a Narrow Biological Level—A Hierarchical and Semi-Quantitative Reassessment of Genomic, Redox, and Metabolic Targeting
    Richard Z. Cheng · 2026 · Preprints.org
30. Harnessing Oxidative Stress to Kill Hepatocellular Carcinoma Cancer Cells: The Power of Methylselenic Acid and/or Pharmacological Ascorbate Combination—An In Vitro Study
    Aseel O. Rataan, Amjad Z. Alrosan, Haneen A. Amawi, Lana K Rababah, Osama Abo Alrob, Ayman T. Fazaa · 2026 · Advances in Pharmacological and Pharmaceutical Sciences
31. Generation of oxidative stress as an anticancer therapeutic strategy : Investigating the mechanism of action of vitamin C, auranofin and their combination
    Nadine El Banna · 2019 · theses.fr (ABES)
32. Pharmacological Ascorbate Restrains Epithelial–Mesenchymal Transition and Invasion in Glioblastoma Cells via Extracellular H2O2 Generation
    Onsurang Wattanathamsan, Naphat Chantaravisoot, Rungnapa Bootsri, Nuttiya Kalpongnukul, Napatsakon Youngsanbhu, Claudia R. Oliva, Corinne E. Griguer, Visarut Buranasudja · 2026 · International Journal of Molecular Sciences
33. Vitamins as radiosensitizers exploring mechanisms and preliminary cancer treatment prospects
    Yuying Zhou, Baixue Wu, Yu Liang, Xin Cao, Wenbo Zhang, Linjie Zhang, Meng Zhao, Yiwen Zhang, Anqi Zhao, Wenlu Chen et al. · 2026 · Radiation Medicine and Protection
34. Unlocking the epigenetic potential of ascorbic acid (Vitamin C) in cancer therapy
    Shahin Vahora, Vishal Shah, Avani Farasrami, Bhavesh Patel · 2026 · Indian Journal of Clinical Biochemistry
35. Spatially restricted iron-metabolism-associated stress programs prime invasive mesenchymal glioblastoma states in human tissue-context models
    Christophe Petry, Ambra-Stella Boecke, Aso Omer Mohammed, Nishitha S Ghariwala, Vatsal D. Jariwala, Mohammad A. Al Shhab, Oliver Buchholz, Ioannis Vasilikos, Julia M. Nakagawa, Andreas Vlachos et al. · 2026 · Neuro-Oncology
36. Beyond redox: vitamin C in signaling, epigenetic regulation and protein modification—relevance to cancer therapy
    Amisha S. H, Sandra Nixon, Hanumappa Ananda, Manasa Nune, Vinay Kumar Rao · 2026 · Clinical Epigenetics
37. Magnetically Activatable Solid Lipid Nanocomposites for Chemodynamic–Hyperthermia Combination Cancer Therapy
    Mohammadreza Esmaeili, Samaneh Abbasian, Reza Saber, Mohammad Moeini · 2026 · ACS Applied Nano Materials
38. Crosslink Between Neuroinflammation and Oxidative/Nitrosative Status in the Glioblastoma Tumor Microenvironment: Prognostic and Theranostic Impact
    Narimene Beder, Mourad Belkhelfa, Lynda Hassani, Yamina Yousfi, Amina Adel, Toufik Selmane, Souhil Tliba · 2026 · Journal of Neuroimmune Pharmacology
39. Combined Molecular Hydrogen and Vitamin C Treatment in Irradiated Normal and Cancer Cell Models: An Exploratory In Vitro Study and Case Reports
    Michiko Miyakawa, Songbai Zhang, Jinan Behnan, Yu Ivy Zhang, Claudia Morganti, Keisuke Ito, Pauline Isakson, Per Uhlén, Ayako Miyakawa · 2026 · Medical Sciences
40. IV Vitamin C with Chemotherapy for Cisplatin-Ineligible Bladder Cancer Patients: A Forgotten Group
    John Arthur Taylor, Rahul Atul Parikh, Qi Chen, Benjamin Leeland Woolbright, Ping Chen, Junqiang Dai, Mihaela Sardiu, Joya He, Jeanne Drisko · 2026 · Antioxidants
41. Endothelial Redox Dysregulation in Pulmonary Arterial Hypertension: Compartmentalized Mechanisms and Therapeutic Implications
    Santiago Moreno-Caceres, David P. Marciano · 2026 · International Journal of Molecular Sciences
42. Nano-vitamin C and Iron-Loaded Polymeric Nanocarriers Cooperatively Amplify Oxidative Cancer Cell Death
    Rajkumar Sahoo, Suman Mandal, Nayana Mukherjee, Santanu Shaw, Nikhil Ranjan Jana · 2026 · ACS Applied Bio Materials