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Antitumoral effects of pharmacological ascorbate on gastric cancer cells: GLUT1 expression may not tell the whole story

Corti, A., Belcastro, E., & Alfonso Pompella, C. (2018) · Theranostics · doi:10.7150/thno.29864 · Cited by 12

Auranofin and Pharmacologic Ascorbate as Radiomodulators in the Treatment of Pancreatic Cancer

Steers, G. J., Chen, G. Y., O’Leary, B. R., Du, J., Beek, H. V., & Cullen, J. J. (2022) · Antioxidants · doi:10.3390/antiox11050971 · Cited by 12

A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

Hoshi, K., Messina, M. S., Ohata, J., Chung, C. Y., & Chang, C. J. (2022) · Nature Protocols · doi:10.1038/s41596-022-00694-7 · Cited by 12

Nanomedicine alleviates doxorubicin-induced cardiotoxicity and enhances chemotherapy synergistic chemodynamic therapy

He, Y., Liu, X., Xu, Z., Gao, J., Luo, Q., He, Y., Zhang, X., Gao, D., & Wang, D. (2024) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2024.03.013 · Cited by 11

Iron oxide nanozymes enhanced by ascorbic acid for macrophage-based cancer therapy

Yi, Z., Yang, X., Liang, Y., & Tong, S. (2024) · Nanoscale · doi:10.1039/d4nr01208a · Cited by 11

L-ascorbic acid and the evolution of multicellular eukaryotes

Edgar, J. A. (2019) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2019.06.001 · Cited by 11

Clinical Targeting of Altered Metabolism in High-Grade Glioma

Scott, A. J., Lyssiotis, C. A., & Wahl, D. R. (2021) · The Cancer Journal · doi:10.1097/ppo.0000000000000550 · Cited by 11

Distinct functions between ferrous and ferric iron in lung cancer cell growth

Hinokuma, H., Kanamori, Y., Ikeda, K., Li, H., Maruno, M., Yamane, T., Maeda, A., Nita, A., Shimoda, M., Niimura, M., et al. (2023) · Cancer Science · doi:10.1111/cas.15949 · Cited by 12

Determination of intracellular ascorbic acid using tandem mass spectrometry

Abe, C., Higuchi, O., Matsumoto, A., & Miyazawa, T. (2022) · The Analyst · doi:10.1039/d1an02160e · Cited by 11

Iron-based biomarkers for personalizing pharmacological ascorbate therapy in glioblastoma: insights from a phase 2 clinical trial

Petronek, M. S., Bodeker, K. L., Lee, C., Teferi, N., Eschbacher, K. L., Jones, K. A., Loeffler, B. T., Smith, B. J., Buatti, J. M., Magnotta, V. A., et al. (2024) · Journal of Neuro-Oncology · doi:10.1007/s11060-024-04571-z · Cited by 10

Microbial metabolites for cancer immunotherapy: Current evidence and future directions

Wang, X., Liang, J.-J., Duan, X., & Chen, G. (2025) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2025.10.005 · Cited by 12

Ascorbic acid analogue 6-Deoxy-6-[18F] fluoro-L-ascorbic acid as a tracer for identifying human colorectal cancer with SVCT2 overexpression

He, P., Zhang, B., Zou, Y., Zhang, Y., Zha, Z., Long, Y., Qiu, J., Shen, W., Lin, X., Li, Z., et al. (2021) · Translational Oncology · doi:10.1016/j.tranon.2021.101055 · Cited by 10

Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer

Tesfay, L., Paul, B. T., Hegde, P., BREWER, M. A., Habbani, S. F., Jellison, E. R., Moore, T. M., Wu, H., Torti, S. V., & Torti, F. M. (2022) · Scientific Reports · doi:10.1038/s41598-022-24391-3 · Cited by 10

A promising redox cycle-based strategy for designing a catechol-type diphenylbutadiene as a potent prooxidative anti-melanoma agent

Dai, F., Du, Y., Zheng, Y.-L., & Zhou, B. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.11.018 · Cited by 10

Quantum chemical insight into the effects of the local electron environment on T2*-based MRI

Petronek, M. S., St‐Aubin, J., Lee, C., Spitz, D. R., Gillan, E. G., Allen, B. G., & Magnotta, V. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-00305-7 · Cited by 10

Fe-doped mesoporous silica catalyzes ascorbic acid oxidation for tumor-specific therapy in scaffold

Shuai, C., Chen, X., He, C., Chen, M., Peng, S., & Yang, W. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113251 · Cited by 10

Repurposing Clemastine to Target Glioblastoma Cell Stemness

Sun, M. A., Yang, R. R., Liu, H., Wang, W., Song, X., Hu, B., Reynolds, N., Roso, K., Chen, L. H., Greer, P. K., et al. (2023) · Cancers · doi:10.3390/cancers15184619 · Cited by 9

Activatable near-infrared fluorescence and chemical exchange saturation transfer MRI multimodal imaging probe for tumor detection in vitro and in vivo

Karan, S., Cho, J., Tran, C. T. N., Cho, M. Y., Lee, H., Naskar, R., Hwang, I., Pradhan, S., Park, H. S., Han, E. H., et al. (2024) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2024.135839 · Cited by 9

CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer

Ma, X., Zhang, B., Yin, X., Yang, S., Lin, Z., Yang, Y., & Zhou, X. (2025) · Breast Cancer Research · doi:10.1186/s13058-025-02039-0 · Cited by 9

Effect of Physiological Concentrations of Vitamin C on the Inhibitation of Hydroxyl Radical Induced Light Emission from Fe2+-EGTA-H2O2 and Fe3+-EGTA-H2O2 Systems In Vitro

Nowak, M. S., Tryniszewski, W., Sarniak, A., Włodarczyk, A., Nowak, P. J., & Nowak, D. (2021) · Molecules · doi:10.3390/molecules26071993 · Cited by 9

Therapeutic Efficacy of Pharmacological Ascorbate on Braf Inhibitor Resistant Melanoma Cells In Vitro and In Vivo

Niessner, H., Burkard, M., Leischner, C., Renner, O., Plöger, S., Meraz-Torres, F., Böcker, M., Hirn, C., Lauer, U. M., Venturelli, S., et al. (2022) · Cells · doi:10.3390/cells11071229 · Cited by 9

Mitochondrial respiration inhibitor enhances the anti-tumor effect of high-dose ascorbic acid in castration-resistant prostate cancer

Qiu, J., Yang, T., Long, Y., He, P., Shen, W., Zhang, B., Shi, X., Peng, L., Li, Z., & Zhang, X. (2022) · Journal of Molecular Medicine · doi:10.1007/s00109-022-02273-5 · Cited by 9

Copper( ii )-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H 2 O 2 self-supply and glutathione depletion

Zhang, M., Xue, H., Yang, J., Zhao, X., Mei, X., Sun, W., Qiu, J., & Zhu, Z. (2024) · Biomaterials Science · doi:10.1039/d3bm01922e · Cited by 9

Highly Sensitive Sensor Based on Pt@MnO 2 /rGO Nanosheets as a Platform for Real-time Monitoring Cellular ROS and its Application in Diverse Cancers

Jiao, J., Wen, L., Wang, Z., Han, B., Zhao, L., & Chen, Q. (2020) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/ab8367 · Cited by 9

Pretreatment serum vitamin level predicts severity of radiation‐induced oral mucositis in patients with nasopharyngeal carcinoma

Chen, G., Jiang, H., Jiang, D., Wu, Q., Li, Z., Hua, X., Hu, X., Zhao, H., Wang, X., Yu, H., et al. (2020) · Head & Neck · doi:10.1002/hed.26576 · Cited by 9

[18F]KS1, a novel ascorbate-based ligand images ROS in tumor models of rodents and nonhuman primates

Damuka, N., Bashetti, N., Mintz, A., Bansode, A. H., Miller, M. D., Krizan, I. M., Furdui, C. M., Bhoopal, B., Gollapelli, K. K., Kumar, J. V. S., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113937 · Cited by 9

Three-Dimensional Regulation of Ferroptosis at the Intersection of Iron, Sulfur, and Oxygen Executing Scrap and Build Toward Evolution

Toyokuni, S., Kong, Y., Zheng, H., Maeda, Y. K., Katabuchi, M., & Motooka, Y. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0142 · Cited by 9

Ascorbate Alters Iron Metabolism to Drive Anticancer Toxicity

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The role of redox-active iron metabolism in the selective toxicity of pharmacological ascorbate in cancer therapy

Schoenfeld, J. D., Spitz, D. R., Allen, B. G., Buettner, G. R., Cullen, J. J., Domann, F. E., & Weiner, G. J. (2018) · doi:10.17077/etd.yahmbqfe

Pharmacologic Ascorbate Influences Multiple Cellular Pathways Preferentially in Cancer Cells

Chen, Q., Polireddy, K., Chen, P., Balusu, R., Wang, T., & Dong, R. (2020) · CRC Press eBooks · doi:10.1201/9781003017493-3

Pharmacological Ascorbate Enhances the Response of Non-Small Cell Lung Cancer (NSCLC) to Radiation and Chemotherapy Via Disruptions of Redox Active Iron Leading to Increased H2O2

Allen, B. G., Schoenfeld, J. D., Sibenaller, Z. A., Mapuskar, K. A., Furqan, M., Hejleh, T. A., Wagner, B. A., Cullen, J. J., Buettner, G. R., Buatti, J. M., et al. (2016) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2016.06.594 · Cited by 1

H2O2-mediated Cytotoxicity of Pharmacologic Ascorbate Concentrations to Neuroblastoma Cells: Potential Role of Lactate and Ferritin

Deubzer, B., Mayer, F. B., Kuçi, Z., Niewisch, M. R., Merkel, G., Handgretinger, R., & Bruchelt, G. (2010) · Cellular Physiology and Biochemistry · doi:10.1159/000315098 · Cited by 63