Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
Bayne, Lauren J., Beatty, Gregory L., Jhala, Nirag, Clark, Carolyn E., Rhim, Andrew D., Stanger, Ben Z., Vonderheide, Robert H.·2012·Cancer Cell
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- Inflammatory networks and immune surveillance of pancreatic carcinomaRobert H. Vonderheide, Lauren J. Bayne · 2013 · Current Opinion in Immunology
- T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal AdenocarcinomaIngunn M. Stromnes, Ayaka Hulbert, Robert Hamilton Pierce, Philip D. Greenberg, Sunil R. Hingorani · 2017 · Cancer Immunology Research
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- Interleukin-6 in inflammatory and malignant diseases of the pancreasMarina Lesina, Sonja M. Wörmann, Patrick Neuhöfer, Liang Song, Hana Algül · 2014 · Seminars in Immunology
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