Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
Bayne, Lauren J., Beatty, Gregory L., Jhala, Nirag, Clark, Carolyn E., Rhim, Andrew D., Stanger, Ben Z., Vonderheide, Robert H.·2012·Cancer Cell
Cited by (952)
Items 201–300 of 952
- Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous NeuroblastomaYumeng Mao, Nina Eißler, Katarina Le Blanc, John Inge Johnsen, Per Kogner, Rolf W. Kiessling · 2016 · Clinical Cancer Research
- Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic CancerShintaro Takeuchi, Muhammad Baghdadi, Takahiro Tsuchikawa, Haruka Wada, Toru Nakamura, Hirotake Abe, Sayaka Nakanishi, Yuu Usui, Kohtaro Higuchi, Mizuna Takahashi et al. · 2015 · Cancer Research
- Spatiotemporally Controllable Distribution of Combination Therapeutics in Solid Tumors by Dually Modified BacteriaLu Wang, Zhenping Cao, Mengmeng Zhang, Sisi Lin, Jinyao Liu · 2021 · Advanced Materials
- Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacyHaixia Long, Qingzhu Jia, Liuyang Wang, Wen‐Feng Fang, Zhongyu Wang, Tao Jiang, Fei Zhou, Jin Zheng, Jiani Huang, Li Zhou et al. · 2022 · Cancer Cell
- Complex role for the immune system in initiation and progression of pancreatic cancerKristin S. Inman · 2014 · World Journal of Gastroenterology
- Metastatic progression is associated with dynamic changes in the local microenvironmentNicole M. Aiello, David Lawrence Bajor, Robert J. Norgard, Amine Sahmoud, Neha Bhagwat, Minh N. Pham, Toby C. Cornish, Christine A. Iacobuzio–Donahue, Robert H. Vonderheide, Ben Z. Stanger · 2016 · Nature Communications
- The biological underpinnings of therapeutic resistance in pancreatic cancerGregory Lawrence Beatty, Gregor Werba, Costas Andreas Lyssiotis, Diane M. Simeone · 2021 · Genes & Development
- Role of immune cells in pancreatic cancer from bench to clinical applicationJae Hyuck Chang, Yongjian Jiang, Venu Gopal Pillarisetty · 2016 · Medicine
- GEMMs as preclinical models for testing pancreatic cancer therapiesAarthi Gopinathan, Jennifer P. Morton, Duncan Ian Jodrell, Owen James Sansom · 2015 · Disease Models & Mechanisms
- Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancerDelphine Goehrig, Jérémy Nigri, Rémi Samain, Zhichong Wu, Paola Cappello, Gaëlle Gabiane, Xinyi Zhang, Yajie Zhao, In-San Kim, Marie Chanal et al. · 2018 · Gut
- Epigenetic and Transcriptional Control of the Epidermal Growth Factor Receptor Regulates the Tumor Immune Microenvironment in Pancreatic CancerJinyang Li, Salina Yuan, Robert J. Norgard, Fangxue Yan, Yu Huining Sun, Il‐Kyu Kim, Allyson J. Merrell, Yogev Sela, Yanqing Jiang, Natarajan V. Bhanu et al. · 2020 · Cancer Discovery
- Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modelingPriyanshu Shukla, Sriya Yeleswarapu, Marcel Alexander Heinrich, Jai Prakash, Falguni Pati · 2022 · Biofabrication
- An Immunosuppressive Dendritic Cell Subset Accumulates at Secondary Sites and Promotes Metastasis in Pancreatic CancerJustin A. Kenkel, William W. Tseng, Matthew G. Davidson, Lorna L. Tolentino, Okmi Choi, Nupur Bhattacharya, E. Scott Seeley, Daniel A. Winer, Nathan Edward Reticker-Flynn, Edgar G. Engleman · 2017 · Cancer Research
- Systemic Reprogramming of Monocytes in CancerMáté Kiss, Aarushi Audhut Caro, Geert Raes, Damya Laoui · 2020 · Frontiers in Oncology
- Chimeric antigen receptor-modified T cells for the treatment of solid tumors: Defining the challenges and next stepsGregory Lawrence Beatty, Mark H. O’Hara · 2016 · Pharmacology & Therapeutics
- Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancerHeidi Griesmann, Christof Drexel, Nada Milosevic, Bence Sipos, Jonas Rosendahl, Thomas Mathias Gress, Patrick Michl · 2016 · Gut
- Therapeutic options for the management of pancreatic cancerMaria L Rossi · 2014 · World Journal of Gastroenterology
- Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironmentК.-С. Н. Атретханы, Marina S. Drutskaya, Sergei A. Nedospasov, Sergei I. Grivennikov, Dmitry V. Kuprash · 2016 · Pharmacology & Therapeutics
- Patients with pancreatic adenocarcinoma exhibit elevated levels of myeloid-derived suppressor cells upon progression of diseaseJoseph Markowitz, Taylor Brooks, Megan Christina Duggan, Bonnie K. Paul, Xueliang Jeff Pan, Lai Wei, Zachary B. Abrams, Eric A. Luedke, Gregory B. Lesinski, Bethany L. Mundy-Bosse et al. · 2014 · Cancer Immunology Immunotherapy
- A mathematical model for pancreatic cancer growth and treatmentsYoram Louzoun, Chuan Xue, Gregory B. Lesinski, Avner Friedman · 2014 · Journal of Theoretical Biology
- Regulation of ROS in myeloid-derived suppressor cells through targeting fatty acid transport protein 2 enhanced anti-PD-L1 tumor immunotherapyAdeleye Oluwatosin Adeshakin, Wan Liu, Funmilayo Oladunni Adeshakin, Lukman Olalekan Afolabi, Mengqi Zhang, Guizhong Zhang, Lulu Wang, Zhihuan Li, Lilong Lin, Qin Cao et al. · 2021 · Cellular Immunology
- Pancreatic cancer and its stroma: A conspiracy theoryZhihong Xu · 2014 · World Journal of Gastroenterology
- Deciphering the role of stroma in pancreatic cancerMeghna Waghray, Malica Yalamanchili, Marina Pasca di Magliano, Diane M. Simeone · 2013 · Current Opinion in Gastroenterology
- Chemotherapy and tumor microenvironment of pancreatic cancerLiu, Qiaofei, Liao, Quan, Zhao, Yupei · 2017 · Cancer Cell International
- Inflammation-Induced NFATc1–STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by Kras G12DSandra Baumgart, NM Chen, Jens Thomas Siveke, Alexander Otto König, Jin‐San Zhang, Shiv K. Singh, Elmar Wolf, Marek Bartkuhn, Iréne Esposito, Elisabeth Heßmann et al. · 2014 · Cancer Discovery
- Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic CancerTulasigeri M. Totiger, Supriya Srinivasan, Venkatakrishna Rao Jala, Purushottam Lamichhane, Austin R. Dosch, Alexander A. Gaidarski, Chandrashekhar G. Joshi, Shobith Rangappa, Jason A. Castellanos, Praveen Kumar Vemula et al. · 2018 · Molecular Cancer Therapeutics
- Tuning the Tumor Myeloid Microenvironment to Fight CancerNadine S. Jahchan, Adriana M. Mujal, Joshua L. Pollack, Mikhail Binnewies, Venkataraman Sriram, Leonard M. Reyno, Matthew F. Krummel · 2019 · Frontiers in Immunology
- IL-17-Producing Cells in Tumor Immunity: Friends or Foes?Da‐Sol Kuen, Byung‐Seok Kim, Yeonseok Chung · 2020 · Immune Network
- Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCsMastio, Jérôme, Condamine, Thomas, Dominguez, George, Kossenkov, Andrew V., Donthireddy, Laxminarasimha, Veglia, Filippo, Lin, Cindy, Wang, Fang, Fu, Shuyu, Zhou, Jie et al. · 2019 · Journal of Experimental Medicine
- Tumor-induced myeloid dysfunction and its implications for cancer immunotherapyMichelle Nicole Messmer, Colleen S. Netherby, Debarati Banik, Scott I. Abrams · 2014 · Cancer Immunology Immunotherapy
- Stromal reengineering to treat pancreas cancerIngunn M. Stromnes, Kathleen E. DelGiorno, Philip D. Greenberg, Sunil R. Hingorani · 2014 · Carcinogenesis
- The complex landscape of pancreatic cancer metabolismC. M. Sousa, Alec C. Kimmelman · 2014 · Carcinogenesis
- Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant TreatmentKendall C. Shibuya, Vikas Goel, Wei Xiong, Jonathan G. Sham, Seth M. Pollack, Allison M. Leahy, Samuel H. Whiting, Matthew M. Yeh, Cassian Yee, Stanley R. Riddell et al. · 2014 · PLoS ONE
- Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockadeSebastian Rune Nielsen, Jan E. Strøbech, Edward R. Horton, René Jackstadt, Anu Laitala, Marina Crespo Bravo, Giorgia Maltese, Adina R. D. Jensen, Raphael Reuten, Maria Rafaeva et al. · 2021 · Nature Communications
- B cell–Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic CancerBhalchandra Mirlekar, Daniel E. Michaud, Samuel J. Lee, Nancy Porterfield Kren, Cameron Harris, Kevin G. Greene, Emily C. Goldman, Gaorav P. Gupta, Ryan Courtney Fields, William G. Hawkins et al. · 2020 · Cancer Immunology Research
- Macropinocytosis in cancer-associated fibroblasts is dependent on CaMKK2/ARHGEF2 signaling and functions to support tumor and stromal cell fitnessZhang, Yijuan, Recouvreux, M. Victoria, Jung, Michael, Galenkamp, Koen M.O., Li, Yunbo, Zagnitko, Olga, Scott, David A., Lowy, Andrew M., Commisso, Cosimo · 2021 · Cancer Discovery
- Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitmentVernon T. Phan, Xiumin Wu, Jason H. Cheng, Rebecca X. Sheng, Alicia S. Chung, Guanglei Zhuang, Christopher Tran, Qinghua Song, Marcin Kowanetz, Amy Sambrone et al. · 2013 · Proceedings of the National Academy of Sciences
- Immunotherapy in Pancreatic Cancer: Why Do We Keep Failing? A Focus on Tumor Immune Microenvironment, Predictive Biomarkers and Treatment OutcomesAlessandro Di Federico, Mirta Mosca, Rachele Pagani, Riccardo Carloni, Giorgio Frega, Andrea De Giglio, Alessandro Rizzo, Dalia Ricci, Simona Tavolari, Mariacristina Di Marco et al. · 2022 · Cancers
- Radiotherapy and CD40 Activation Separately Augment Immunity to Checkpoint Blockade in CancerAndrew J. Rech, Hannah Dada, Jonathan J. Kotzin, Jorge Henao‐Mejia, Andy J. Minn, Christina Twyman-Saint Victor, Robert H. Vonderheide · 2018 · Cancer Research
- CD40 immunotherapy for pancreatic cancerRobert H. Vonderheide, David Lawrence Bajor, Rafael Winograd, Rebecca A. Evans, Lauren J. Bayne, Gregory Lawrence Beatty · 2013 · Cancer Immunology Immunotherapy
- Epithelial and stromal co-evolution and complicity in pancreatic cancerHingorani, Sunil R. · 2023 · Nature Reviews Cancer
- Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cellsPeng Xiao, Xiaopeng Wan, Bijun Cui, Yang Liu, Chenyang Qiu, Jiabing Rong, Mingzhu Zheng, Yinjing Song, Luoquan Chen, Jia He et al. · 2015 · OncoImmunology
- Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancerGuoliang Yang, Wenyan Shen, Yan Zhang, Mengyao Liu, Lianhua Zhang, Qiang Liu, Hui Hui Lu, Juanjie Bo · 2017 · Oncotarget
- Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastasesMitchell Thorn, Prajna Guha, Marissa Cunetta, N. Joseph Espat, George Miller, Richard Paul Junghans, Steven C. Katz · 2016 · Cancer Gene Therapy
- S100A9 Regulates MDSCs-Mediated Immune Suppression via the RAGE and TLR4 Signaling Pathways in Colorectal CarcinomaMao Huang, Rui Wu, Lu Chen, Qi Peng, Shue Li, Yan Zhang, Lan Zhou, Liang Duan · 2019 · Frontiers in Immunology
- IL6 Receptor Blockade Enhances Chemotherapy Efficacy in Pancreatic Ductal AdenocarcinomaKristen B. Long, Graham M. Tooker, Evan Tooker, Santiago Lombo Luque, Jae Woo Lee, Xiaoqing Pan, Gregory Lawrence Beatty · 2017 · Molecular Cancer Therapeutics
- The Interplay among miRNAs, Major Cytokines, and Cancer-Related InflammationChiranjib Chakraborty, Ashish Ranjan Sharma, Garima Sharma, Sang‐Soo Lee · 2020 · Molecular Therapy — Nucleic Acids
- Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasisBrian Yong Lee, Elizabeth K. J. Hogg, Christopher Below, Alexander Kononov, Adrián Blanco‐Gómez, Felix Heider, Jingshu Xu, Colin Hutton, Xiaohong Mary Zhang, Tamara Scheidt et al. · 2021 · Nature Communications
- Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinomaW-Q Wang, L. Liu, H-X Xu, C-T Wu, J-F Xiang, Jiejie Xu, C. Liu, J Long, Q-X Ni, Xianjun Yu · 2016 · British journal of surgery
- Breast cancer–derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironmentXinming Su, Yalin Xu, Gregory C. Fox, Jingyu Xiang, Kristin A. Kwakwa, Jennifer L. Davis, Jad I. Belle, Wen‐Chih Lee, Winghing Wong, Francesca Fontana et al. · 2021 · Journal of Clinical Investigation
- CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in miceZhang, Yaqing, Yan, Wei, Mathew, Esha, Bednar, Filip, Wan, Shanshan, Collins, Meredith A., Evans, Rebecca A., Welling, Theodore H., Vonderheide, Robert H., di Magliano, Marina Pasca · 2014 · Cancer Immunology Research
- CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinomaXiaomeng Liu, Rong Tang, Jin Xu, Zhen Tan, Chen Liang, Qingcai Meng, Yubin Lei, Jie Hua, Yiyin Zhang, Jiang Liu et al. · 2023 · Gut
- Cancer cell-intrinsic mechanisms driving acquired immune toleranceEhsan Ghorani, Charles Swanton, Sergio A. Quezada · 2023 · Immunity
- Pancreatic Cancer Microenvironment and Cellular Composition: Current Understandings and Therapeutic ApproachesTruong, Linh-Huyen, Pauklin, Siim · 2021 · Cancers
- The prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesisReichert, Maximilian, Takano, Shigetsugu, von Burstin, Johannes, Kim, Sang-Bae, Lee, Ju-Seog, Ihida-Stansbury, Kaori, Hahn, Christopher, Heeg, Steffen, Schneider, Günter, Rhim, Andrew D. et al. · 2013 · Genes & Development
- Myeloid-derived suppressor cells and their role in pancreatic cancerMatthew Pergamo, George Miller · 2016 · Cancer Gene Therapy
- Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progressionJeremy S. Wilson, Romano C. Pirola, Minoti Vivek Apte · 2014 · Frontiers in Physiology
- Immunotherapy in pancreatic ductal adenocarcinoma: an emerging entity?İbrahim Halil Şahin, Gokce Askan, Zhengming Hu, Eileen Mary O'Reilly · 2017 · Annals of Oncology
- The hepatic pre-metastatic niche in pancreatic ductal adenocarcinomaDemi S. Houg, Maarten F. Bijlsma · 2018 · Molecular Cancer
- Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axisGaia Bellomo, Carolyn Rainer, Valeria Quaranta, Yuliana Astuti, Meirion Raymant, Elzbieta Boyd, Ruth Stafferton, Fiona Campbell, Paula Ghaneh, Christopher Michael Halloran et al. · 2022 · Gut
- Macrophages: Gatekeepers of Tissue IntegrityYonit Lavin, Miriam Mérad · 2013 · Cancer Immunology Research
- Impact of tumour associated macrophages in pancreatic cancerAinhoa Mielgo, Michael C. Schmid · 2013 · BMB Reports
- G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancersWenbin Li, Xinghua Zhang, Yongkang Chen, Yibin Xie, Jiancheng Liu, Qiang Feng, Yi Wang, Wei Yuan, Jie Ma · 2016 · Protein & Cell
- Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic reviewRexiati Ruze, Jianlu Song, Xinpeng Yin, Yuan Chen, Ruiyuan Xu, Chengcheng Wang, Yupei Zhao · 2023 · Signal Transduction and Targeted Therapy
- Convergent inducers and effectors of T cell paralysis in the tumour microenvironmentDouglas Hanahan, Olivier Alain Michielin, Mikaël J. Pittet · 2024 · Nature reviews. Cancer
- Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patientsErin E. Talbert, Heather L. Lewis, Matthew R. Farren, Mitchell L. Ramsey, Jeffery M. Chakedis, Priyani V. Rajasekera, Ericka N. Haverick, Angela Sarna, Mark Bloomston, Timothy Michael Pawlik et al. · 2018 · Journal of Cachexia Sarcopenia and Muscle
- High-salt diet inhibits tumour growth in mice via regulating myeloid-derived suppressor cell differentiationWei He, Jinzhi Xu, Ruoyu Mu, Qiu Li, Dalun Lv, Zhen Dong Huang, Junfeng Zhang, Chunming Wang, Lei Dong · 2020 · Nature Communications
- Targeting tumor-associated macrophages to combat pancreatic cancerRan Cui, Wen Yue, Edmund C. Lattime, Mark N. Stein, Qing Xu, Xiang‐Lin Tan · 2016 · Oncotarget
- Myeloid‐derived suppressor cells as effectors of immune suppression in cancerAthalia Rachel Pyzer, Leandra Cole, Jacalyn M. Rosenblatt, David Avigan · 2016 · International Journal of Cancer
- Anti-VEGF therapy resistance in ovarian cancer is caused by GM-CSF-induced myeloid-derived suppressor cell recruitmentNaoki Horikawa, Kaoru Abiko, Noriomi Matsumura, Tsukasa Baba, Junzo Hamanishi, Ken D Yamaguchi, Ryusuke Murakami, Mana Taki, Masayo Ukita, Yuko Hosoe et al. · 2020 · British Journal of Cancer
- Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor PhenotypeLéa Paolini, Clément Adam, Céline Beauvillain, Laurence Preisser, Simon Blanchard, Pascale Pignon, Valérie Seegers, Louise-Marie Chevalier, Mario Campone, Romuald Wernert et al. · 2020 · Cancer Immunology Research
- Alternative RNA splicing and cancerSali Liu, Chonghui Cheng · 2013 · Wiley Interdisciplinary Reviews - RNA
- Current Limitations and Novel Perspectives in Pancreatic Cancer TreatmentSteve Robatel, Mirjam Schenk · 2022 · Cancers
- Genetically engineered mouse models of cancer reveal new insights about the antitumor immune responseMichel J.P. DuPage, Tyler Jacks · 2013 · Current Opinion in Immunology
- The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancerNicola E. Annels, Victoria E. Shaw, Rachel F. Gabitass, Lucinda Jane Billingham, Pippa G. Corrie, Martin McKinlay Eatock, Juan W. Valle, David B. Smith, Jonathan Wadsley, David Cunningham et al. · 2013 · Cancer Immunology Immunotherapy
- Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 SecretionFengkai Li, Shunsuke Kitajima, Susumu Kohno, Akiyo Yoshida, Shoichiro Tange, Soichiro Sasaki, Nobuhiro Okada, Yuuki Nishimoto, Hayato Muranaka, Naoko Nagatani et al. · 2019 · Cancer Research
- Myeloid‐Derived Suppressor Cells and Therapeutic Strategies in CancerHiroshi Katoh, Masahiko Watanabe · 2015 · Mediators of Inflammation
- The interplay between innate and adaptive immunity in cancer shapes the productivity of cancer immunosurveillanceRenee B. Chang, Gregory Lawrence Beatty · 2020 · Journal of Leukocyte Biology
- Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in miceBenson Chellakkan Selvanesan, Dinesh Chandra, Wilber Quispe‐Tintaya, Arthee Jahangir, Ankur S. Patel, Kiran Meena, Rodrigo Alberto Alves da Silva, Madeline Friedman, Lisa R. Gabor, Olivia R Khouri et al. · 2022 · Science Translational Medicine
- Pancreatic cancer: The microenvironment needs attention too!Minoti Vivek Apte, Zhihong Xu, Srinivasa P. Pothula, David Goldstein, Romano C. Pirola, Jeremy S. Wilson · 2015 · Pancreatology
- Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer CellsEngin Gürlevik, Bettina Fleischmann-Mundt, Jennifer Brooks, İhsan Ekin Demir, Katja Steiger, Silvia Ribback, Tetyana Yevsa, Norman Woller, Arnold Kloos, Dmitrij Ostroumov et al. · 2016 · Gastroenterology
- Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammationTim D.D. Somerville, Giulia Biffi, Juliane Daßler‐Plenker, Stella K. Hur, Xue‐Yan He, Krysten E. Vance, Koji Miyabayashi, Yali Xu, Diogo Maia-Silva, Olaf Klingbeil et al. · 2020 · eLife
- Kras and tumor immunity: friend or foe?Cullis, Jane, Das, Shipra, Bar-Sagi, Dafna · 2018 · Cold Spring Harbor Perspectives in Medicine
- Cellular determinants and therapeutic implications of inflammation in pancreatic cancerMeredith L. Stone, Gregory Lawrence Beatty · 2019 · Pharmacology & Therapeutics
- The Pleiotropic Effects of the GM-CSF Rheostat on Myeloid Cell Differentiation and Function: More Than a Numbers GameYifan Zhan, Andrew M. Lew, Michaël Chopin · 2019 · Frontiers in Immunology
- Generation of Myeloid Cells in Cancer: The Spleen MattersChong Wu, Qiaomin Hua, Limin Zheng · 2020 · Frontiers in Immunology
- Roles of Neutrophils in Glioma and Brain MetastasesYa-Jui Lin, Kuo‐Chen Wei, Pin‐Yuan Chen, Michael K. Lim, Tsong‐Long Hwang · 2021 · Frontiers in Immunology
- Fas and TRAIL ‘death receptors’ as initiators of inflammation: Implications for cancerSean P. Cullen, Séamus J. Martin · 2015 · Seminars in Cell and Developmental Biology
- The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltrationJennifer Watt, Hemant Mahendrakumar Kocher · 2013 · OncoImmunology
- Recent Advances of Colony-Stimulating Factor-1 Receptor (CSF-1R) Kinase and Its InhibitorsMohammed I. El–Gamal, Shahad K. Al-Ameen, Dania M. Al-Koumi, Mawadda G. Hamad, Nouran A. Jalal, Chang‐Hyun Oh · 2018 · Journal of Medicinal Chemistry
- Biology and therapeutic targeting of tumour‐associated macrophagesTim Beltraminelli, Michele De Palma · 2020 · The Journal of Pathology
- Radiation and Local Anti-CD40 Generate an Effective in situ Vaccine in Preclinical Models of Pancreatic CancerSayeda Yasmin‐Karim, Patrick T. Bruck, Michèle Moreau, Sijumon Kunjachan, Gui Zhen Chen, Rajiv Kumar, Stephanie Grabow, Stephanie K. Dougan, Wilfred F. Ngwa · 2018 · Frontiers in Immunology
- Emerging concepts in pancreatic cancer medicine: targeting the tumor stromaAlbrecht Neeße, Thomas Mathias Gress, David A. Tuveson, Patrick Michl, Sebastian Krug · 2013 · OncoTargets and Therapy
- Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironmentCara C. Schafer, Yong Wang, Kenneth P. Hough, Anandi Sawant, Stefan C. Grant, Victor John Thannickal, Jaroslaw W. Zmijewski, Selvarangan Ponnazhagan, Jessy S. Deshane · 2016 · Oncotarget
- Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1–Specific VHHsMichael Lawrence Dougan, Jessica R. Ingram, Hee‐Jin Jeong, Munir M. Mosaheb, Patrick T. Bruck, Lestat R. Ali, Novalia Pishesha, Olga S. Blomberg, Paul M. Tyler, Mariah M. Servos et al. · 2018 · Cancer Immunology Research
- Using chemo-drugs or irradiation to break immune tolerance and facilitate immunotherapy in solid cancerYawen Zheng, Yan Dou, Lili Duan, Changsheng Cong, Aiqin Gao, Qinghua Lai, Yuping Sun · 2015 · Cellular Immunology
- Chemokine (C‐X‐C motif) ligand 1 and CXCL 2 produced by tumor promote the generation of monocytic myeloid‐derived suppressor cellsHuifang Shi, Xiaoqing Han, Yingying Sun, Chao Shang, Min Wei, Xueqing Ba, Xianlu Zeng · 2018 · Cancer Science
- Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapyDespina Siolas, Emily Vucic, Emma Kurz, Cristina H Hajdu, Dafna Bar‐Sagi · 2020 · Cell Reports
- Stress Granules Determine the Development of Obesity-Associated Pancreatic CancerGuillaume Fonteneau, Alexandra Redding, Hannah Hoag-Lee, Edward S. Sim, Stefan Heinrich, Matthias M. Gaida, Elda Grabocka · 2022 · Cancer Discovery
- Pro-tumorigenic functions of macrophages at the primary, invasive and metastatic tumor siteElaheh Nasrollahzadeh, Sepideh Razi, Mahsa Keshavarz‐Fathi, Massimiliano Mazzone, Nima Rezaei · 2020 · Cancer Immunology Immunotherapy